High-dose selenium reduces ventilator-associated pneumonia and illness severity in critically ill patients with systemic inflammation

Intensive Care Medicine

Volumn 37, Issue 7, 2011, Pages 1120-1127

  Manzanares, William ^a   Biestro, Alberto ^a   Torre, María H ^b   Galusso, Federico ^a   Facchin, Gianella ^b   Hardy, Gil ^c  

^a HOSPITAL DE CLÍNICAS   (Uruguay)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

Glutathione peroxidase; Hospital acquired pneumonia; Selenium; Systemic inflammation; Ventilator associated pneumonia

Indexed keywords

GLUTATHIONE PEROXIDASE 3; PLACEBO; SELENIOUS ACID; SELENITE;

ACUTE KIDNEY FAILURE; ADULT; AGED; ANEMIA; ARTICLE; BLOOD SAMPLING; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN ISCHEMIA; CLINICAL ARTICLE; CONTINUOUS INFUSION; CRITICALLY ILL PATIENT; DISEASE SEVERITY; DRUG EFFICACY; DRUG MEGADOSE; ENZYME ACTIVITY; FEMALE; HOSPITAL ACQUIRED PNEUMONIA; HOSPITAL DISCHARGE; HUMAN; INTENSIVE CARE; LIVER DYSFUNCTION; LOADING DRUG DOSE; MALE; NUTRITIONAL INTOLERANCE; PHARMACODYNAMICS; PHASE 2 CLINICAL TRIAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY FAILURE; SHOCK; SINGLE BLIND PROCEDURE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOCYTOPENIA; VENTILATOR ASSOCIATED PNEUMONIA;

ANALYSIS OF VARIANCE; APACHE; CHI-SQUARE DISTRIBUTION; CRITICAL ILLNESS; FEMALE; HUMANS; MALE; MIDDLE AGED; PLACEBOS; PNEUMONIA, VENTILATOR-ASSOCIATED; PROSPECTIVE STUDIES; SELENIUM; SEVERITY OF ILLNESS INDEX; SINGLE-BLIND METHOD; STATISTICS, NONPARAMETRIC; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TREATMENT OUTCOME;

EID: 79961028064     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-011-2212-6     Document Type: Article

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