-
1
-
-
72249111162
-
Anti-FGF2 approaches as a strategy to compensate resistance to anti-VEGF therapy: Long-pentraxin 3 as a novel antiangiogenic FGF2-antagonist
-
ALESSI P, LEALI D, CAMOZZI M, CANTELMO A, ALBINI A, PRESTA M (2009). Anti-FGF2 approaches as a strategy to compensate resistance to anti-VEGF therapy: long-pentraxin 3 as a novel antiangiogenic FGF2-antagonist. Eur Cytokine Netw 20: 225-234.
-
(2009)
Eur Cytokine Netw
, vol.20
, pp. 225-234
-
-
Alessi, P.1
Leali, D.2
Camozzi, M.3
Cantelmo, A.4
Albini, A.5
Presta, M.6
-
2
-
-
0016207226
-
Differentiation of vascular endothelium in the chick chorioallantois: A structural and autoradiographic study
-
AUSPRUNK DH, KNIGHTON DR, FOLKMAN J (1974). Differentiation of vascular endothelium in the chick chorioallantois: a structural and autoradiographic study. Dev Biol 38: 237-248.
-
(1974)
Dev Biol
, vol.38
, pp. 237-248
-
-
Ausprunk, D.H.1
Knighton, D.R.2
Folkman, J.3
-
3
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
BATCHELOR TT, SORENSEN AG, DI TE, ZHANG WT, DUDA DG, COHEN KS, KOZAK KR, CAHILL DP, CHEN PJ, ZHU M, ANCUKIEWICZ M, MRUGALA MM, PLOTKIN S, DRAPPATZ J, LOUIS DN, IVY P, SCADDEN DT, BENNER T, LOEFFLER JS, WEN PY, JAIN RK (2007). AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11: 83-95.
-
(2007)
Cancer Cell
, vol.11
, pp. 83-95
-
-
Batchelor, T.T.1
Sorensen, A.G.2
Di, T.E.3
Zhang, W.T.4
Duda, D.G.5
Cohen, K.S.6
Kozak, K.R.7
Cahill, D.P.8
Chen, P.J.9
Zhu, M.10
Ancukiewicz, M.11
Mrugala, M.M.12
Plotkin, S.13
Drappatz, J.14
Louis, D.N.15
Ivy, P.16
Scadden, D.T.17
Benner, T.18
Loeffler, J.S.19
Wen, P.Y.20
Jain, R.K.21
more..
-
4
-
-
0036316243
-
Regulation of microvascular permeability by vascular endothelial growth factors
-
BATES DO, HILLMAN NJ, WILLIAMS B, NEAL CR, POCOCK TM (2002). Regulation of microvascular permeability by vascular endothelial growth factors. J Anat 200: 581-597.
-
(2002)
J Anat
, vol.200
, pp. 581-597
-
-
Bates, D.O.1
Hillman, N.J.2
Williams, B.3
Neal, C.R.4
Pocock, T.M.5
-
5
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
BERGERS G, HANAHAN D (2008). Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8: 592-603.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
6
-
-
0038713666
-
Resistance to cytotoxic and anti-angiogenic anticancer agents: Similarities and differences
-
BROXTERMAN HJ, LANKELMA J, HOEKMAN K (2003). Resistance to cytotoxic and anti-angiogenic anticancer agents: similarities and differences. Drug Resist Updat 6: 111-127.
-
(2003)
Drug Resist Updat
, vol.6
, pp. 111-127
-
-
Broxterman, H.J.1
Lankelma, J.2
Hoekman, K.3
-
7
-
-
0036948242
-
Intussusceptive angiogenesis--the alternative to capillary sprouting
-
BURRI PH, DJONOV V (2002). Intussusceptive angiogenesis--the alternative to capillary sprouting. Mol Aspects Med 23: S1-27.
-
(2002)
Mol Aspects Med
, vol.23
-
-
Burri, P.H.1
Djonov, V.2
-
8
-
-
6944234979
-
Intussusceptive angiogenesis: Its emergence, its characteristics, and its significance
-
BURRI PH, HLUSHCHUK R, DJONOV V (2004). Intussusceptive angiogenesis: its emergence, its characteristics, and its significance. Dev Dyn 231: 474-488.
-
(2004)
Dev Dyn
, vol.231
, pp. 474-488
-
-
Burri, P.H.1
Hlushchuk, R.2
Djonov, V.3
-
9
-
-
68549085490
-
Branching morphogenesis and antiangiogenesis candidates: Tip cells lead the way
-
CARMELIET P, DE SF, LOGES S, MAZZONE M (2009). Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way. Nat Rev Clin Oncol 6: 315-326.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 315-326
-
-
Carmeliet, P.1
De, S.F.2
Loges, S.3
Mazzone, M.4
-
10
-
-
26644471951
-
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
-
CASANOVAS O, HICKLIN DJ, BERGERS G, HANAHAN D (2005). Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8: 299-309.
-
(2005)
Cancer Cell
, vol.8
, pp. 299-309
-
-
Casanovas, O.1
Hicklin, D.J.2
Bergers, G.3
Hanahan, D.4
-
11
-
-
0242573142
-
Vascular remodeling by intussusceptive angiogenesis
-
DJONOV V, BAUM O, BURRI PH (2003). Vascular remodeling by intussusceptive angiogenesis. Cell Tissue Res 314: 107-117.
-
(2003)
Cell Tissue Res
, vol.314
, pp. 107-117
-
-
Djonov, V.1
Baum, O.2
Burri, P.H.3
-
12
-
-
33847048710
-
Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications
-
DOME B, HENDRIX MJ, PAKU S, TOVARI J, TIMAR J (2007). Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications. Am J Pathol 170: 1-15.
-
(2007)
Am J Pathol
, vol.170
, pp. 1-15
-
-
Dome, B.1
Hendrix, M.J.2
Paku, S.3
Tovari, J.4
Timar, J.5
-
13
-
-
0037099598
-
PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging
-
DREVS J, MULLER-DRIVER R, WITTIG C, FUXIUS S, ESSER N, HUGENSCHMIDT H, KONERDING MA, ALLEGRINI PR, WOOD J, HENNIG J, UNGER C, MARME D (2002). PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging. Cancer Res 62: 4015-4022.
-
(2002)
Cancer Res
, vol.62
, pp. 4015-4022
-
-
Drevs, J.1
Muller-Driver, R.2
Wittig, C.3
Fuxius, S.4
Esser, N.5
Hugenschmidt, H.6
Konerding, M.A.7
Allegrini, P.R.8
Wood, J.9
Hennig, J.10
Unger, C.11
Marme, D.12
-
14
-
-
58149190795
-
Pathways mediating resistance to vascular endothelial growth factor-targeted therapy
-
ELLIS LM, HICKLIN DJ (2008). Pathways mediating resistance to vascular endothelial growth factor-targeted therapy. Clin Cancer Res 14: 6371-6375.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6371-6375
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
15
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
FOLKMAN J (1971). Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
16
-
-
0032557564
-
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
-
GERBER HP, DIXIT V, FERRARA N (1998). Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 273: 13313-13316.
-
(1998)
J Biol Chem
, vol.273
, pp. 13313-13316
-
-
Gerber, H.P.1
Dixit, V.2
Ferrara, N.3
-
17
-
-
57649135172
-
A role for VEGF as a negative regulator of pericyte function and vessel maturation
-
GREENBERG JI, SHIELDS DJ, BARILLAS SG, ACEVEDO LM, MURPHY E, HUANG J, SCHEPPKE L, STOCKMANN C, JOHNSON RS, ANGLE N, CHERESH DA (2008). A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature 456: 809-813.
-
(2008)
Nature
, vol.456
, pp. 809-813
-
-
Greenberg, J.I.1
Shields, D.J.2
Barillas, S.G.3
Acevedo, L.M.4
Murphy, E.5
Huang, J.6
Scheppke, L.7
Stockmann, C.8
Johnson, R.S.9
Angle, N.10
Cheresh, D.A.11
-
18
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
HANAHAN D, FOLKMAN J (1996). Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
19
-
-
77949494504
-
Resistance to antiangiogenic therapy is directed by vascular phenotype, vessel stabilization, and maturation in malignant melanoma
-
HELFRICH I, SCHEFFRAHN I, BARTLING S, WEIS J, VON F, V, MIDDLETON M, KATO M, ERGUN S, SCHADENDORF D (2010). Resistance to antiangiogenic therapy is directed by vascular phenotype, vessel stabilization, and maturation in malignant melanoma. J Exp Med 207: 491-503.
-
(2010)
J Exp Med
, vol.207
, pp. 491-503
-
-
Helfrich, I.1
Scheffrahn, I.2
Bartling, S.3
Weis, J.4
Von, F.V.5
Middleton, M.6
Kato, M.7
Ergun, S.8
Schadendorf, D.9
-
20
-
-
36148937125
-
Tumour vascularization: Sprouting angiogenesis and beyond
-
HILLEN F, GRIFFIOEN AW (2007). Tumour vascularization: sprouting angiogenesis and beyond. Cancer Metastasis Rev 26: 489-502.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 489-502
-
-
Hillen, F.1
Griffioen, A.W.2
-
21
-
-
36249004373
-
The synergistic action of a VEGF-receptor tyrosine-kinase inhibitor and a sensitizing PDGF-receptor blocker depends upon the stage of vascular maturation
-
HLUSHCHUK R, BAUM O, GRUBER G, WOOD J, DJONOV V (2007). The synergistic action of a VEGF-receptor tyrosine-kinase inhibitor and a sensitizing PDGF-receptor blocker depends upon the stage of vascular maturation. Microcirculation 14: 813-825.
-
(2007)
Microcirculation
, vol.14
, pp. 813-825
-
-
Hlushchuk, R.1
Baum, O.2
Gruber, G.3
Wood, J.4
Djonov, V.5
-
22
-
-
53149098943
-
Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiation
-
HLUSHCHUK R, RIESTERER O, BAUM O, WOOD J, GRUBER G, PRUSCHY M, DJONOV V (2008). Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiation. Am J Pathol 173: 1173-1185.
-
(2008)
Am J Pathol
, vol.173
, pp. 1173-1185
-
-
Hlushchuk, R.1
Riesterer, O.2
Baum, O.3
Wood, J.4
Gruber, G.5
Pruschy, M.6
Djonov, V.7
-
23
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
JAIN RK (2005). Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307: 58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
24
-
-
41149138113
-
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer
-
JAIN RK (2008). Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer. Nat Rev Cancer 8: 309-316.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 309-316
-
-
Jain, R.K.1
-
26
-
-
33846834110
-
Bevacizumab, a humanized anti-angiogenic monoclonal antibody for the treatment of colorectal cancer
-
KRAMER I, LIPP HP (2007). Bevacizumab, a humanized anti-angiogenic monoclonal antibody for the treatment of colorectal cancer. J Clin Pharm Ther 32: 1-14.
-
(2007)
J Clin Pharm Ther
, vol.32
, pp. 1-14
-
-
Kramer, I.1
Lipp, H.P.2
-
27
-
-
0027217832
-
Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries
-
KU DD, ZALESKI JK, LIU S, BROCK TA (1993). Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries. Am J Physiol 265: H586-H592.
-
(1993)
Am J Physiol
, vol.265
-
-
Ku, D.D.1
Zaleski, J.K.2
Liu, S.3
Brock, T.A.4
-
28
-
-
57749092182
-
Combination of antiangiogenesis with chemotherapy for more effective cancer treatment
-
MA J, WAXMAN DJ (2008). Combination of antiangiogenesis with chemotherapy for more effective cancer treatment. Mol Cancer Ther 7: 3670-3684.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3670-3684
-
-
Ma, J.1
Waxman, D.J.2
-
29
-
-
67650733812
-
Intussusceptive angiogenesis and its role in vascular morphogenesis, patterning, and remodeling
-
MAKANYA AN, HLUSHCHUK R, DJONOV VG (2009). Intussusceptive angiogenesis and its role in vascular morphogenesis, patterning, and remodeling. Angiogenesis 12: 113-123.
-
(2009)
Angiogenesis
, vol.12
, pp. 113-123
-
-
Makanya, A.N.1
Hlushchuk, R.2
Djonov, V.G.3
-
30
-
-
0037246430
-
The Snark is a Boojum: The continuing problem of drug resistance in the antiangiogenic era
-
MILLER KD, SWEENEY CJ, SLEDGE GW, JR. (2003). The Snark is a Boojum: the continuing problem of drug resistance in the antiangiogenic era. Ann Oncol 14: 20-28.
-
(2003)
Ann Oncol
, vol.14
, pp. 20-28
-
-
Miller, K.D.1
Sweeney, C.J.2
Sledge Jr., G.W.3
-
31
-
-
16644394469
-
Can tumor angiogenesis be inhibited without resistance?
-
(Eds. M. Clauss, G. Breier). EXS. Birkhäuser, Basel
-
MILLER KD, SWEENEY CJ, SLEDGE GW, JR. (2005). Can tumor angiogenesis be inhibited without resistance?. In Mechanisms of Angiogenesis (Eds. M. Clauss, G. Breier). EXS. Birkhäuser, Basel, pp. 95-112.
-
(2005)
Mechanisms of Angiogenesis
, pp. 95-112
-
-
Miller, K.D.1
Sweeney, C.J.2
Sledge Jr., G.W.3
-
32
-
-
33749503264
-
KRN951, a highly potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, has antitumor activities and affects functional vascular properties
-
NAKAMURA K, TAGUCHI E, MIURA T, YAMAMOTO A, TAKAHASHI K, BICHAT F, GUILBAUD N, HASEGAWA K, KUBO K, FUJIWARA Y, SUZUKI R, KUBO K, SHIBUYA M, ISAE T (2006). KRN951, a highly potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, has antitumor activities and affects functional vascular properties. Cancer Res 66: 9134-9142.
-
(2006)
Cancer Res
, vol.66
, pp. 9134-9142
-
-
Nakamura, K.1
Taguchi, E.2
Miura, T.3
Yamamoto, A.4
Takahashi, K.5
Bichat, F.6
Guilbaud, N.7
Hasegawa, K.8
Kubo, K.9
Fujiwara, Y.10
Suzuki, R.11
Kubo, K.12
Shibuya, M.13
Isae, T.14
-
33
-
-
12344263868
-
KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth
-
NAKAMURA K, YAMAMOTO A, KAMISHOHARA M, TAKAHASHI K, TAGUCHI E, MIURA T, KUBO K, SHIBUYA M, ISOE T (2004). KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth. Mol Cancer Ther 3: 1639-1649.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1639-1649
-
-
Nakamura, K.1
Yamamoto, A.2
Kamishohara, M.3
Takahashi, K.4
Taguchi, E.5
Miura, T.6
Kubo, K.7
Shibuya, M.8
Isoe, T.9
-
34
-
-
23844516785
-
PTK787/ZK222584, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor, reduces uptake of the contrast agent GdDOTA by murine orthotopic B16/BL6 melanoma tumours and inhibits their growth in vivo
-
RUDIN M, MCSHEEHY PM, ALLEGRINI PR, RAUSCH M, BAUMANN D, BECQUET M, BRECHT K, BRUEGGEN J, FERRETTI S, SCHAEFFER F, SCHNELL C, WOOD J (2005). PTK787/ZK222584, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor, reduces uptake of the contrast agent GdDOTA by murine orthotopic B16/BL6 melanoma tumours and inhibits their growth in vivo. NMR Biomed 18: 308-321.
-
(2005)
NMR Biomed
, vol.18
, pp. 308-321
-
-
Rudin, M.1
McSheehy, P.M.2
Allegrini, P.R.3
Rausch, M.4
Baumann, D.5
Becquet, M.6
Brecht, K.7
Brueggen, J.8
Ferretti, S.9
Schaeffer, F.10
Schnell, C.11
Wood, J.12
-
35
-
-
0141842637
-
CEP-7055: A novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models
-
RUGGERI B, SINGH J, GINGRICH D, ANGELES T, ALBOM M, YANG S, CHANG H, ROBINSON C, HUNTER K, DOBRZANSKI P, JONES-BOLIN S, PRITCHARD S, AIMONE L, KLEIN-SZANTO A, HERBERT JM, BONO F, SCHAEFFER P, CASELLAS P, BOURIE B, PILI R, ISAACS J, ATOR M, HUDKINS R, VAUGHT J, MALLAMO J, DIONNE C (2003). CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models. Cancer Res 63: 5978-5991.
-
(2003)
Cancer Res
, vol.63
, pp. 5978-5991
-
-
Ruggeri, B.1
Singh, J.2
Gingrich, D.3
Angeles, T.4
Albom, M.5
Yang, S.6
Chang, H.7
Robinson, C.8
Hunter, K.9
Dobrzanski, P.10
Jones-Bolin, S.11
Pritchard, S.12
Aimone, L.13
Klein-Szanto, A.14
Herbert, J.M.15
Bono, F.16
Schaeffer, P.17
Casellas, P.18
Bourie, B.19
Pili, R.20
Isaacs, J.21
Ator, M.22
Hudkins, R.23
Vaught, J.24
Mallamo, J.25
Dionne, C.26
more..
-
36
-
-
66249101249
-
Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors
-
SENNINO B, KUHNERT F, TABRUYN SP, MANCUSO MR, HU-LOWE DD, KUO CJ, MCDONALD DM (2009). Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors. Cancer Res 69: 4527-4536.
-
(2009)
Cancer Res
, vol.69
, pp. 4527-4536
-
-
Sennino, B.1
Kuhnert, F.2
Tabruyn, S.P.3
Mancuso, M.R.4
Hu-Lowe, D.D.5
Kuo, C.J.6
McDonald, D.M.7
-
37
-
-
68149171591
-
Mode of action and clinical impact of VEGF signaling inhibitors
-
SOLTAU J, DREVS J (2009). Mode of action and clinical impact of VEGF signaling inhibitors. Expert Rev Anticancer Ther 9: 649-662.
-
(2009)
Expert Rev Anticancer Ther
, vol.9
, pp. 649-662
-
-
Soltau, J.1
Drevs, J.2
-
38
-
-
42349114587
-
Endothelial sprouting and angiogenesis: Matrix metalloproteinases in the lead
-
VAN HINSBERGH VW, KOOLWIJK P (2008). Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead. Cardiovasc Res 78: 203-212.
-
(2008)
Cardiovasc Res
, vol.78
, pp. 203-212
-
-
van Hinsbergh, V.W.1
Koolwijk, P.2
-
39
-
-
0030823968
-
Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells
-
YOSHIJI H, HARRIS SR, THORGEIRSSON UP (1997). Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells. Cancer Res 57: 3924-3928.
-
(1997)
Cancer Res
, vol.57
, pp. 3924-3928
-
-
Yoshiji, H.1
Harris, S.R.2
Thorgeirsson, U.P.3
|