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Volumn 31, Issue 8, 2011, Pages 1751-1759

Variants in the inflammatory IL6 and MPO genes modulate stroke susceptibility through main effects and gene-gene interactions

Author keywords

Cerebrovascular disease; genetics; inflammation; regeneration and recovery; risk factors

Indexed keywords

INTERLEUKIN 6; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR;

EID: 79961006752     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.27     Document Type: Review
Times cited : (18)

References (38)
  • 1
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • DOI 10.1093/bioinformatics/bth457
    • Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-5 (Pubitemid 40202029)
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 4
    • 33845903040 scopus 로고    scopus 로고
    • Odds ratio based multifactor-dimensionality reduction method for detecting gene - Gene interactions
    • DOI 10.1093/bioinformatics/btl557
    • Chung Y, Lee SY, Elston RC, Park T (2007) Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics 23: 71-6 (Pubitemid 46017858)
    • (2007) Bioinformatics , vol.23 , Issue.1 , pp. 71-76
    • Chung, Y.1    Lee, S.Y.2    Elston, R.C.3    Park, T.4
  • 6
    • 12744260011 scopus 로고    scopus 로고
    • The neuroprotective role of inflammation in nervous system injuries
    • Correale J, Villa A (2004) The neuroprotective role of inflammation in nervous system injuries. J Neurol 251: 1304-16
    • (2004) J Neurol , vol.251 , pp. 1304-1016
    • Correale, J.1    Villa, A.2
  • 7
    • 4744362285 scopus 로고    scopus 로고
    • Proinflammatory genetic profiles in subjects with history of ischemic stroke
    • DOI 10.1161/01.STR.0000140740.19421.fe
    • Flex A, Gaetani E, Papaleo P, Straface G, Proia AS, Pecorini G, Tondi P, Pola P, Pola R (2004) Proinflamma-tory genetic profiles in subjects with history of ischemic stroke. Stroke 35:2270-5 (Pubitemid 39311248)
    • (2004) Stroke , vol.35 , Issue.10 , pp. 2270-2275
    • Flex, A.1    Gaetani, E.2    Papaleo, P.3    Straface, G.4    Proia, A.S.5    Pecorini, G.6    Tondi, P.7    Pola, P.8    Pola, R.9
  • 9
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A double-edged sword
    • DOI 10.1038/nri1882, PII N1882
    • Hansson GK, Libby P (2006) The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 6:508-19 (Pubitemid 43980523)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.7 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 12
    • 0038464980 scopus 로고    scopus 로고
    • Myeloperoxidase polymorphisms in brain infarction. Association with infarct size and functional outcome
    • DOI 10.1016/S0021-9150(02)00041-2
    • Hoy A, Leininger-Muller B, Poirier O, Siest G, Gautier M, Elbaz A, Amarenco P, Visvikis S (2003) Myeloperox-idase polymorphisms in brain infarction. Association with infarct size and functional outcome. Atherosclerosis 167:223-30 (Pubitemid 36775336)
    • (2003) Atherosclerosis , vol.167 , Issue.2 , pp. 223-230
    • Hoy, A.1    Leininger-Muller, B.2    Poirier, O.3    Siest, G.4    Gautier, M.5    Elbaz, A.6    Amarenco, P.7    Visvikis, S.8
  • 15
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
    • Lakhan SE, Kirchgessner A, Hofer M (2009) Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med 7:97
    • (2009) J Transl Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 16
    • 77950221224 scopus 로고    scopus 로고
    • Advances in genomic analysis of stroke: What have we learned and where are we headed?
    • Lanktree MB, Dichgans M, Hegele RA (2010) Advances in genomic analysis of stroke: what have we learned and where are we headed? Stroke 41:825-32
    • (2010) Stroke , vol.41 , pp. 825-832
    • Lanktree, M.B.1    Dichgans, M.2    Hegele, R.A.3
  • 18
    • 67349256414 scopus 로고    scopus 로고
    • Association of three-gene interaction among MTHFR, ALOX5AP and NOTCH3 with thrombotic stroke: A multicenter case-control study
    • Liu J, Sun K, Bai Y, Zhang W, Wang X, Wang Y, Wang H, Chen J, Song X, Xin Y, Liu Z, Hui R (2009) Association of three-gene interaction among MTHFR, ALOX5AP and NOTCH3 with thrombotic stroke: a multicenter case-control study. Hum Genet 125:649-56
    • (2009) Hum Genet , vol.125 , pp. 649-656
    • Liu, J.1    Sun, K.2    Bai, Y.3    Zhang, W.4    Wang, X.5    Wang, Y.6    Wang, H.7    Chen, J.8    Song, X.9    Xin, Y.10    Liu, Z.11    Hui, R.12
  • 19
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • DOI 10.1038/sj.bjp.0706400, PII 0706400
    • Lucas SM, Rothwell NJ, Gibson RM (2006) The role of inflammation in CNS injury and disease. Br J Pharmacol 147(Suppl 1):S232-40 (Pubitemid 43077281)
    • (2006) British Journal of Pharmacology , vol.147 , Issue.SUPPL. 1
    • Lucas, S.-M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 21
    • 77949431495 scopus 로고    scopus 로고
    • Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloprotei-nase-9 genes significantly influence functional outcome after stroke
    • Manso H, Krug T, Sobral J, Albergaria I, Gaspar G, Ferro JM, Oliveira SA, Vicente AM (2010) Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloprotei-nase-9 genes significantly influence functional outcome after stroke. BMC Med Genet 11:40
    • (2010) BMC Med Genet , vol.11 , pp. 40
    • Manso, H.1    Krug, T.2    Sobral, J.3    Albergaria, I.4    Gaspar, G.5    Ferro, J.M.6    Oliveira, S.A.7    Vicente, A.M.8
  • 22
    • 0033202098 scopus 로고    scopus 로고
    • Intimal-medial thickness of the common carotid arteries and lower limbs atherosclerosis in the elderly
    • Mattace Raso F, Rosato M, Talerico A, Cotronei P, Mattace R (1999) Intimal-medial thickness of the common carotid arteries and lower limbs atherosclerosis in the elderly. Minerva Cardioangiol 47:321-7
    • (1999) Minerva Cardioangiol , vol.47 , pp. 321-327
    • Mattace Raso, F.1    Rosato, M.2    Talerico, A.3    Cotronei, P.4    Mattace, R.5
  • 23
    • 0345411335 scopus 로고    scopus 로고
    • The ubiquitous nature of epistasis in determining susceptibility to common human diseases
    • DOI 10.1159/000073735
    • Moore JH (2003) The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered 56:73-82 (Pubitemid 37465073)
    • (2003) Human Heredity , vol.56 , Issue.1-3 , pp. 73-82
    • Moore, J.H.1
  • 24
    • 33745599582 scopus 로고    scopus 로고
    • A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility
    • DOI 10.1016/j.jtbi.2005.11.036, PII S0022519305005217
    • Moore JH, Gilbert JC, Tsai CT, Chiang FT, Holden T, Barney N, White BC (2006) A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility. J Theor Biol 241:252-61 (Pubitemid 43993963)
    • (2006) Journal of Theoretical Biology , vol.241 , Issue.2 , pp. 252-261
    • Moore, J.H.1    Gilbert, J.C.2    Tsai, C.-T.3    Chiang, F.-T.4    Holden, T.5    Barney, N.6    White, B.C.7
  • 25
    • 34447638516 scopus 로고    scopus 로고
    • Low-grade inflammation in chronic infectious diseases: Paradigm of periodontal infections
    • DOI 10.1196/annals.1366.032, Neuroendocrine and Immune Crosstalk
    • Moutsopoulos NM, Madianos PN (2006) Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections. Ann NY Acad Sci 1088:251-64 (Pubitemid 47092053)
    • (2006) Annals of the New York Academy of Sciences , vol.1088 , pp. 251-264
    • Moutsopoulos, N.M.1    Madianos, P.N.2
  • 26
    • 78049232851 scopus 로고    scopus 로고
    • Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: A Go-DARTS study
    • Palmer CN, Kimber CH, Doney AS, Proia AS, Morris AD, Gaetani E, Quarta M, Smith RC, Pola R (2010) Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: a Go-DARTS study. Diabetes 59:2945-8
    • (2010) Diabetes , vol.59 , pp. 2945-2948
    • Palmer, C.N.1    Kimber, C.H.2    Doney, A.S.3    Proia, A.S.4    Morris, A.D.5    Gaetani, E.6    Quarta, M.7    Smith, R.C.8    Pola, R.9
  • 29
    • 0034973569 scopus 로고    scopus 로고
    • Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
    • DOI 10.1086/321276
    • Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Parl FF, Moore JH (2001) Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet 69:138-47 (Pubitemid 32614026)
    • (2001) American Journal of Human Genetics , vol.69 , Issue.1 , pp. 138-147
    • Ritchie, M.D.1    Hahn, L.W.2    Roodi, N.3    Bailey, L.R.4    Dupont, W.D.5    Parl, F.F.6    Moore, J.H.7
  • 30
    • 43249112515 scopus 로고    scopus 로고
    • Role of inflammatory markers in brain ischemia
    • DOI 10.1097/WCO.0b013e3282ffafbf, PII 0001905220080600000022
    • Rodŕguez-Yáñez M, Castillo J (2008) Role of inflammatory markers in brain ischemia. Curr Opin Neurol 21:353-7 (Pubitemid 351653988)
    • (2008) Current Opinion in Neurology , vol.21 , Issue.3 , pp. 353-357
    • Rodriguez-Yanez, M.1    Castillo, J.2
  • 31
    • 0034724305 scopus 로고    scopus 로고
    • Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: Potential implications for inflammation and plaque instability
    • Schieffer B, Schieffer E, Hilfiker-Kleiner D, Hilfiker A, Kovanen PT, Kaartinen M, Nussberger J, Harringer W, Drexler H (2000) Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability. Circulation 101:1372-8 (Pubitemid 30169857)
    • (2000) Circulation , vol.101 , Issue.12 , pp. 1372-1378
    • Schieffer, B.1    Schieffer, E.2    Hilfiker-Kleiner, D.3    Hilfiker, A.4    Kovanen, P.T.5    Kaartinen, M.6    Nussberger, J.7    Harringer, W.8    Drexler, H.9
  • 32
    • 68149168582 scopus 로고    scopus 로고
    • Myeloperoxidase: A useful biomarker for cardiovascular disease risk stratification?
    • Schindhelm RK, Van der Zwan LP, Teerlink T, Scheffer PG (2009) Myeloperoxidase: a useful biomarker for cardiovascular disease risk stratification? Clin Chem 55: 1462-70
    • (2009) Clin Chem , vol.55 , pp. 1462-1670
    • Schindhelm, R.K.1    Van Der Zwan, L.P.2    Teerlink, T.3    Scheffer, P.G.4
  • 35
    • 0035108136 scopus 로고    scopus 로고
    • Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
    • Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P (2001) Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol 158:879-91 (Pubitemid 32221781)
    • (2001) American Journal of Pathology , vol.158 , Issue.3 , pp. 879-891
    • Sugiyama, S.1    Okada, Y.2    Sukhova, G.K.3    Virmani, R.4    Heinecke, J.W.5    Libby, P.6
  • 36
    • 35648965192 scopus 로고    scopus 로고
    • Interleukin-6 -174G/C polymorphism and ischemic stroke: A systematic review
    • DOI 10.1161/STROKEAHA.107.492231, PII 0000767020071100000033
    • Tso AR, Merino JG, Warach S (2007) Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review. Stroke 38:3070-5 (Pubitemid 350035706)
    • (2007) Stroke , vol.38 , Issue.11 , pp. 3070-3075
    • Tso, A.R.1    Merino, J.G.2    Warach, S.3
  • 37
    • 33847644971 scopus 로고    scopus 로고
    • The inflammatory response in stroke
    • DOI 10.1016/j.jneuroim.2006.11.014, PII S0165572806004693, Inflammation, Neurodegeneration and Neuroprotection in the Central Nervous System
    • Wang Q, Tang XN, Yenari MA (2007) The inflammatory response in stroke. J Neuroimmunol 184:53-68 (Pubitemid 46365991)
    • (2007) Journal of Neuroimmunology , vol.184 , Issue.1-2 , pp. 53-68
    • Wang, Q.1    Tang, X.N.2    Yenari, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.