Cytokines and Fever

International Archives of Allergy and Immunology

Volumn 109, Issue 4, 1996, Pages 301-307

  Luheshi, Giamal ^a   Rothwell, Nancy ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cytokines; Fever; IL 1; IL 6; Neuroimmunology; TNF

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

BRAIN; FEVER; HUMAN; IMMUNOPATHOGENESIS; NEUROENDOCRINE SYSTEM; NEUROIMMUNOLOGY; PRIORITY JOURNAL; REVIEW; TISSUE INJURY;

EID: 0029932804     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237256     Document Type: Article

References (30)

1. Hopkins SJ. Rothwell NJ: Cytokines and the nervous system. I. Expression and recognition. Trends Neurosei 1995:18:83-88.
2. Kluger MJ: Fever: Role of pyrogens and cryo-gens. Physiol Rev 1991;71:93-127.
3. Rothwell NJ: Funetions and mechanisms of interleukin I in the brain. Trends Pharmacol Sei 1991;12:430-436.
4. Widenmen BP. Reichardt P. Rath U. Thcilmann L. Schule B. Ho AD. Schlick E, Kempeni J, Hunstein W, Kommerel B: Phase-1 trial of intravenous continuous infusion of tumor necrosis factor in advanced metastatic carcinomas. J Cancer Res Clin Oncol 1989:115:189-192.
5. Cannon JG, Tompkins RG, Cielfand JA, Michic HR, Stanford GG, van der Meer JWM, Endres S, Lonneman G, Corsetti J, Chemow B, Wilmore DW, Wolff SM, Burke JF, Dinarello CA: Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. J Infect Dis 1990; 161:79-84.
6. Michie HR. Manogue KR. Spriggs DR. Revliaug A, O'Dwyer S, Dinarello CA, Cerami A, Wolff SM, Wilmore DW: Detection of circulating tumor necrosis factor after endotoxin administration, N Engl.1 Med 1988:318:1481-1486.
7. LcMay LG. Vander AJ. Kluger MJ: Role of interleukin 6 in fever in rats. Am J Physiol 1990: 258:R798-R803.
8. Cooper AL. Rothwell NJ: Mechanisms of early and late hypermetabolism and fever after localised tissue injury in rats. Am.1 Physiol 1991; 261:E698-E705.
9. Daseombe MJ: The pharmacology of fever. Prog Neurobiol 1985:25:327-373.
10. Rothwell NJ: Mechanisms of the pyrogehic actions of cytokines. Eur Cytokine Netw 1990; I: 211-213.
11. Rothwell NJ. Hopkins SJ: Cytokines and the nervous system. II: Actions and mechanisms of action. Trends Neurosei 1995:18:130-136.
12. Milton AS: Thermoregulatory actions of eieo-sanoids in the central nervous system with particular regard to the pathogenesis of lever. Ann NY Acad Sci 1989:539:392-410.
13. Bristow AF. Mosley K. Poole S: Interleukin-1β production in vitro and in vivo in rats and mice measured using specific immunoradiometric assays. J Mol Endocrinol 1991;7:1-7.
14. Long NC. Otterness I. Kunkcl SL. Vander AJ. Kluger MJ: The roles of interleukin-ip and tumour necrosis factor in lipopolysaccharidc fever in rats. Am J Physiol 1990;259:R724-R728.
15. Rothwell NJ. Busbridge NJ. I lumphray H. I lis-sey P: Central actions of interleukin-1β on fever and thermogenesis; in Dinarello CA. Kluger MJ. Powanda JJ. Oppcnhcim J.I (eds): The Physiological and Pathological Effects of Cytokines. New York. Wiley-Liss. 1990, pp 307-311.
16. Luhcshi G, Miller AJ, Brouwer S, Daseombe MJ, Rothwell NJ, Hokins SJ: Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat. Am J Physiol, in press.
17. Long NC, Kunkel SL, Vander AJ, Kluger MJ: Antiserum against TNF enhances LPS fever in the rat. Am J Physiol 1990:258:R332-R337.
18. Stefferl A, Hopkins SJ, Rothwell NJ, Luhcshi GN: The role of TNF-α in fever: Opposing actions of human and murine TNF-α and interactions with IL-lfl in the rat. Br J Pharmacol, in press.
19. Smith BK, Kluger M: Anti-TNF-α antibodies normalized body temperature and enhanced food intake in tumour-bearing rats. Am J Physiol 1993:265:R615-R619.
20. Cooper A. Brouwer S. Turnbul A. Luhcshi G. Hopkins S. Kunkel S. Rothwell NJ: Tumor necrosis factor- α (TNF-α) and fever following peripheral inflammation in the rat. Am J Physiol 1994:36:R1431-R1436.
21. Luhcshi GN. Gay J. Rothwell NJ: Circulating IL-6 is transported into the brain via a saturable transport mechanism in the rat. Br.1 Pharmacol 1994:111:146.
22. −.’ Neural versus humoral mediation. Eur Cytokine Nctw 1994:5:271-273.
23. Banks WA, Ortiz L, Plotkin SR, Kastin AJ: Human interleukin (IL): Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-I beta are transported from blood to brain in the mouse by a shared saturable mechanism. J Pharmacol Exp Titer 1991:259:988-996.
24. Watkins LR, Wieterlack EP, Goehler LE, Mooneyl Heilberger K, Martinez J, Furness L, Smith KP, Maier SF: Ncurocircuitry of stress-induced hyperalgesia. Brain Res 1994;639:283-289.
25. Layé S, Bluthé RM, Kent S, Combe C, Medina C, Pamct P, Kelley K, Dantzer R: Subdiaphrag-matic vagotomy blocks induction of IL-lfl mRNA in mice brain in response to peripheral LPS. AM J Physiol 1995:268:R1327-R1331.
26. Luhcshi G. Hopkins SJ. LcFcuvrc RA. Daseombe MJ. Ghiara P. Rothwell NJ: Importance of brain IL-I type II receptors in fever and ther-mogencsis in the rat. Am J Physiol 1993; 265:E585-E59I.
27. Sims JE. Gayle MA. Slack JL. Alderson MR. Bird TA. Giri JG. Collota F. Re F. Mantovani A. Shancbcck K. Grabstein Kl I. Dower SK: Interleukin-1 signalling occurs exclusively via the type I receptor. Proc Natl Acad Sci USA 1993: 90:6155-6159.
28. Gayle MA. Sims JE. Dower SK. Slack JL: Monoclonal antibody 1994-01 (also known as ALVA-42) reported recognise type II receptor is specific for HLA-DR alpha and beta chains. Cytokine 1994:6:83-86.
29. Grccnfcder SA. Nunes P. Kwee L. Labow M. Chizzonitc RA. Ju G: Molecular cloning and characterization of a second subunit of the interleukin I receptor complex. J Biol Client 1995:270:13757-13765.
30. Flower R.I. Rothwell NJ: Lipocortin-1: Cellular mechanisms and clinical relevance. Trends Pharmacol Sci 1994:15:71-76.