Shortened engineered human antibody CH2 domains: Increased stability and binding to the human neonatal Fc receptor

Journal of Biological Chemistry

Volumn 286, Issue 31, 2011, Pages 27288-27293

  Gong, Rui ^a   Wang, Yanping ^a   Feng, Yang ^a   Zhao, Qi ^a   Dimitrov, Dimiter S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BINDERS; COVALENT BONDS; CRYSTAL STRUCTURE; EPITOPES; SULFUR COMPOUNDS;

CONFORMATIONAL EPITOPES; DISULFIDE BONDS; HUMAN ANTIBODIES; N-TERMINALS; NEONATAL FC RECEPTORS; PROTEASE DIGESTION; RANDOM COIL; THERMALLY INDUCED;

STABILITY;

CH 2 ANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIBODY AFFINITY; ANTIBODY ENGINEERING; ANTIBODY ISOLATION; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; MELTING POINT; MOLECULAR RECOGNITION; MOLECULAR STABILITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; RECEPTOR BINDING; TEMPERATURE SENSITIVITY;

EID: 79960992429     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.254219     Document Type: Article

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