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Volumn 284, Issue 21, 2009, Pages 14203-14210
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Engineered human antibody constant domains with increased stability
a
CCRNP
(United States)
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Author keywords
[No Author keywords available]
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Indexed keywords
CIRCULAR DICHROISM;
CONCENTRATION OF;
DISULFIDE BONDS;
HIGHER TEMPERATURES;
HUMAN ANTIBODIES;
HUMAN DISEASE;
PHYSIOLOGICAL TEMPERATURE;
SECONDARY STRUCTURES;
STABLE MUTANTS;
THERMALLY INDUCED;
WILD TYPES;
ANTIBODIES;
DICHROISM;
DIFFERENTIAL SCANNING CALORIMETRY;
MAGNETIC RESONANCE;
MASS SPECTROMETRY;
METABOLISM;
NUCLEAR MAGNETIC RESONANCE;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
SCAFFOLDS;
UREA;
MAGNETIC DOMAINS;
CYSTEINE;
IMMUNOGLOBULIN ANTIBODY;
MUTANT PROTEIN;
DISULFIDE;
IMMUNOGLOBULIN G;
AMINO TERMINAL SEQUENCE;
ANTIBODY ENGINEERING;
ARTICLE;
CARBOXY TERMINAL SEQUENCE;
CONTROLLED STUDY;
DIFFERENTIAL SCANNING CALORIMETRY;
DISULFIDE BOND;
HEAVY CHAIN;
HUMAN;
IMMUNOGLOBULIN CONSTANT REGION;
MOUSE;
MUTANT;
NONHUMAN;
NUCLEOTIDE SEQUENCE;
PRIORITY JOURNAL;
PROTEIN DOMAIN;
PROTEIN FOLDING;
PROTEIN SECONDARY STRUCTURE;
PROTEIN STABILITY;
SEQUENCE ALIGNMENT;
THERMOSTABILITY;
AMINO ACID SEQUENCE;
CHEMISTRY;
CIRCULAR DICHROISM;
GLYCOSYLATION;
MASS SPECTROMETRY;
MOLECULAR GENETICS;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
PLIABILITY;
PROTEIN ENGINEERING;
PROTEIN TERTIARY STRUCTURE;
MURINAE;
AMINO ACID SEQUENCE;
CALORIMETRY, DIFFERENTIAL SCANNING;
CIRCULAR DICHROISM;
DISULFIDES;
GLYCOSYLATION;
HUMANS;
IMMUNOGLOBULIN CONSTANT REGIONS;
IMMUNOGLOBULIN G;
MAGNETIC RESONANCE SPECTROSCOPY;
MASS SPECTROMETRY;
MOLECULAR SEQUENCE DATA;
MUTANT PROTEINS;
PLIABILITY;
PROTEIN ENGINEERING;
PROTEIN STABILITY;
PROTEIN STRUCTURE, SECONDARY;
PROTEIN STRUCTURE, TERTIARY;
SEQUENCE ALIGNMENT;
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EID: 67649782189
PISSN: 00219258
EISSN: 1083351X
Source Type: Journal
DOI: 10.1074/jbc.M900769200 Document Type: Article |
Times cited : (90)
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References (29)
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