-
1
-
-
67249122712
-
Biological barriers to therapy with antisense and siRNA oligonucleotides
-
Juliano, R., Bauman, J., Kang, H., and Ming, X. (2009) Biological barriers to therapy with antisense and siRNA oligonucleotides. Mol Pharm. 6, 686–695.
-
(2009)
Mol Pharm
, vol.6
, pp. 686-695
-
-
Juliano, R.1
Bauman, J.2
Kang, H.3
Ming, X.4
-
2
-
-
0027364174
-
PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules
-
Egholm, M., Buchardt, O., Christensen, L., Behrens, C., Freier, S. M., Driver, D. A., Berg, R. H., Kim, S. K., Nordén, B., and Nielsen, P. E. (1993) PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature 365, 566–568.
-
(1993)
Nature
, vol.365
, pp. 566-568
-
-
Egholm, M.1
Buchardt, O.2
Christensen, L.3
Behrens, C.4
Freier, S.M.5
Driver, D.A.6
Berg, R.H.7
Kim, S.K.8
Nordén, B.9
Nielsen, P.E.10
-
3
-
-
0032699477
-
Morpholino antisense oligomers: The case for an RNase H-independent structural type
-
Summerton, J. (1999) Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim Biophys Acta 1489, 141–158.
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 141-158
-
-
Summerton, J.1
-
4
-
-
33645095226
-
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
-
Ng, E. W., Shima, D. T., Calias, P., Cunningham, E. T., Jr., Guyer, D. R., and Adamis, A. P. (2006) Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 5, 123–132.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 123-132
-
-
Ng, E.W.1
Shima, D.T.2
Calias, P.3
Cunningham, E.T.4
Guyer, D.R.5
Adamis, A.P.6
-
5
-
-
48549097394
-
Accessing the therapeutic potential of immunostimulatory nucleic acids
-
Barchet, W., Wimmenauer, V., Schlee, M., and Hartmann, G. (2008) Accessing the therapeutic potential of immunostimulatory nucleic acids. Curr Opin Immunol. 20, 389–395.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 389-395
-
-
Barchet, W.1
Wimmenauer, V.2
Schlee, M.3
Hartmann, G.4
-
6
-
-
61649097962
-
Theoretic applicability of antisense-mediated exon skipping for duchenne muscular dystrophy mutations
-
Aartsma-Rus, A., Fokkema, I., Verschuuren, J., Ginjaar, I., van Deutekom, J., van Ommen, G. J., and den Dunnen, J. T. (2009) Theoretic applicability of antisense-mediated exon skipping for duchenne muscular dystrophy mutations. Hum Mutat. 30, 293–299.
-
(2009)
Hum Mutat
, vol.30
, pp. 293-299
-
-
Aartsma-Rus, A.1
Fokkema, I.2
Verschuuren, J.3
Ginjaar, I.4
van Deutekom, J.5
van Ommen, G.J.6
Den Dunnen, J.T.7
-
7
-
-
47249138782
-
Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
-
Juliano, R., Alam, M. R., Dixit, V., and Kang, H. (2008) Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. Nucleic Acids Res. 36, 4158–4171.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4158-4171
-
-
Juliano, R.1
Alam, M.R.2
Dixit, V.3
Kang, H.4
-
8
-
-
0028239908
-
The third helix of the antennapedia homeodomain translocates through biological membranes
-
Derossi, D., Joliot, A. H., Chassaing, G., and Prochiantz, A. (1994) The third helix of the antennapedia homeodomain translocates through biological membranes. J Biol Chem. 269, 10444–10450.
-
(1994)
J Biol Chem
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.H.2
Chassaing, G.3
Prochiantz, A.4
-
9
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vivés, E., Brodin, P., and Lebleu, B. (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem. 272, 16010–16017.
-
(1997)
J Biol Chem
, vol.272
, pp. 16010-16017
-
-
Vivés, E.1
Brodin, P.2
Lebleu, B.3
-
10
-
-
75349114584
-
Chemically modified cell-penetrating peptides for the delivery of nucleic acids
-
Mäe, M., El-Andaloussi, S., Lehto, T., and Langel, Ü. (2009) Chemically modified cell-penetrating peptides for the delivery of nucleic acids. Expert Opin Drug Deliv. 6, 1195–1205.
-
(2009)
Expert Opin Drug Deliv
, vol.6
, pp. 1195-1205
-
-
Mäe, M.1
El-Andaloussi, S.2
Lehto, T.3
Langel, Ü.4
-
11
-
-
38949188925
-
Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides
-
Nakase, I., Takeuchi, T., Tanaka, G., and Futaki, S. (2008) Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides. Adv Drug Deliv Rev. 60, 598–607.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 598-607
-
-
Nakase, I.1
Takeuchi, T.2
Tanaka, G.3
Futaki, S.4
-
12
-
-
70349456654
-
Recent advances in the use of cell-penetrating peptides for medical and biological applications
-
Fonseca, S. B., Pereira, M. P., and Kelley, S. O. (2009) Recent advances in the use of cell-penetrating peptides for medical and biological applications. Adv Drug Deliv Rev. 61, 953–964.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 953-964
-
-
Fonseca, S.B.1
Pereira, M.P.2
Kelley, S.O.3
-
13
-
-
77949890248
-
Cell penetrating peptides and their applications: An overview
-
Said Hassane, F., Saleh, A., Abes, R., Gait, M. J., and Lebleu, B. (2010) Cell penetrating peptides and their applications: an overview. Cell Mol Life Sci. 67, 715–728.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 715-728
-
-
Said Hassane, F.1
Saleh, A.2
Abes, R.3
Gait, M.J.4
Lebleu, B.5
-
14
-
-
31544458695
-
Endo-some trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates
-
Abes, S., Williams, D., Prevot, P., Thierry, A., Gait, M. J., and Lebleu, B. (2006) Endo-some trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates. J Control Release 110, 595–604.
-
(2006)
J Control Release
, vol.110
, pp. 595-604
-
-
Abes, S.1
Williams, D.2
Prevot, P.3
Thierry, A.4
Gait, M.J.5
Lebleu, B.6
-
15
-
-
38949206876
-
Cell penetrating peptide conjugates of steric block oligonucleotides
-
Lebleu, B., Moulton, H. M., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J. (2008) Cell penetrating peptide conjugates of steric block oligonucleotides. Adv Drug Deliv Rev. 60, 517–529.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 517-529
-
-
Lebleu, B.1
Moulton, H.M.2
Abes, R.3
Ivanova, G.D.4
Abes, S.5
Stein, D.A.6
Iversen, P.L.7
Arzumanov, A.A.8
Gait, M.J.9
-
16
-
-
0032485884
-
Up-regulation of luciferase gene expression with antisense oligonucleotides: Implications and applications in functional assay development
-
Kang, S. H., Cho, M. J., and Kole, R. (1998) Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development. Biochemistry 37, 6235–6239.
-
(1998)
Biochemistry
, vol.37
, pp. 6235-6239
-
-
Kang, S.H.1
Cho, M.J.2
Kole, R.3
-
17
-
-
56649117680
-
Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: Structure-activity studies
-
Abes, R., Moulton, H. M., Clair, P., Yang, S. T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B. (2008) Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies. Nucleic Acids Res. 36, 6343– 6354.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 6343-6354
-
-
Abes, R.1
Moulton, H.M.2
Clair, P.3
Yang, S.T.4
Abes, S.5
Melikov, K.6
Prevot, P.7
Youngblood, D.S.8
Iversen, P.L.9
Chernomordik, L.V.10
Lebleu, B.11
-
18
-
-
50549093417
-
Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice
-
Jearawiriyapaisarn, N., Moulton, H. M., Buckley, B., Roberts, J., Sazani, P., Fucharoen, S., Iversen, P. L., and Kole, R. (2008) Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice. Mol Ther. 16, 1624–1629.
-
(2008)
Mol Ther
, vol.16
, pp. 1624-1629
-
-
Jearawiriyapaisarn, N.1
Moulton, H.M.2
Buckley, B.3
Roberts, J.4
Sazani, P.5
Fucharoen, S.6
Iversen, P.L.7
Kole, R.8
-
19
-
-
57049102809
-
Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function
-
Yin, H., Moulton, H. M., Seow, Y., Boyd, C., Boutilier, J., Iverson, P., and Wood, M. J. (2008) Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function. Hum Mol Genet. 17, 3909–3918.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3909-3918
-
-
Yin, H.1
Moulton, H.M.2
Seow, Y.3
Boyd, C.4
Boutilier, J.5
Iverson, P.6
Wood, M.J.7
-
20
-
-
70849111210
-
Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy
-
Lehto, T., Abes, R., Oskolkov, N., Suho-rutsenko, J., Copolovici, D. M., Mäger, I., Viola, J. R., Simonson, O., Guterstam, P., Eriste, E., Smith, C. I., Lebleu, B., El-Andaloussi, S., and Langel, Ü. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release 141, 42–51.
-
J Control Release
, vol.141
, pp. 42-51
-
-
Lehto, T.1
Abes, R.2
Oskolkov, N.3
Suho-Rutsenko, J.4
Copolovici, D.M.5
Mäger, I.6
Viola, J.R.7
Simonson, O.8
Guterstam, P.9
Eriste, E.10
Smith, C.I.11
Lebleu, B.12
El-Andaloussi, S.13
Langel, Ü.14
-
21
-
-
24644470131
-
Cellular delivery of peptide nucleic acid by cell-penetrating peptides
-
Kilk, K., and Langel, Ü. (2005) Cellular delivery of peptide nucleic acid by cell-penetrating peptides. Methods Mol Biol. 298, 131–141.
-
(2005)
Methods Mol Biol
, vol.298
, pp. 131-141
-
-
Kilk, K.1
Langel, Ü.2
-
22
-
-
0036368612
-
Synthesis of cell-penetrating peptide-PNA constructs
-
Pooga, M., Soomets, U., Bartfai, T., and Langel, Ü. (2002) Synthesis of cell-penetrating peptide-PNA constructs. Methods Mol Biol. 208, 225–236.
-
(2002)
Methods Mol Biol
, vol.208
, pp. 225-236
-
-
Pooga, M.1
Soomets, U.2
Bartfai, T.3
Langel, Ü.4
-
23
-
-
0022761041
-
Preparation of Boc-[S-(3-nitro-2-pyridinesulfenyl)]-cysteine and its use for unsymmetrical disulfide bond formation
-
Bernatowicz, M. S., Matsueda, R., and Matsueda, G. R. (1986) Preparation of Boc-[S-(3-nitro-2-pyridinesulfenyl)]-cysteine and its use for unsymmetrical disulfide bond formation. Int J Pept Protein Res. 28, 107–112.
-
(1986)
Int J Pept Protein Res
, vol.28
, pp. 107-112
-
-
Bernatowicz, M.S.1
Matsueda, R.2
Matsueda, G.R.3
|