HuR and myogenesis: Being in the right place at the right time

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1813, Issue 9, 2011, Pages 1663-1667

  Von Roretz, Christopher ^a   Beauchamp, Pascal ^a   Di Marco, Sergio ^a   Gallouzi, Imed Eddine ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Caspase; HuR; Myogenesis; Myogenic regulatory factor; Transportin 2

Indexed keywords

CASPASE; CASPASE 3; CASPASE 7; HUR PROTEIN; KARYOPHERIN; MEMBRANE PROTEIN; MESSENGER RNA; MYOD PROTEIN; MYOGENIC FACTOR; MYOGENIN; NUCLEAR PROTEIN; PROTEIN P21; TRANSPORTIN 1; TRANSPORTIN 2; UNCLASSIFIED DRUG;

APOPTOSIS; CELL CYCLE REGULATION; CELL DEATH; CELL DIFFERENTIATION; CELL FATE; CELL NUCLEUS; CYTOPLASM; FEMALE; HELA CELL; HUMAN; MUSCLE CELL; MUSCLE DEVELOPMENT; MYOBLAST; NONHUMAN; NUCLEAR EXPORT SIGNAL; NUCLEAR IMPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIGENS, SURFACE; CASPASES; CELL DIFFERENTIATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; KARYOPHERINS; MUSCLE CELLS; MUSCLE DEVELOPMENT; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 79960925346     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.01.036     Document Type: Review

References (47)

1. Charge S.B., Rudnicki M.A. Cellular and molecular regulation of muscle regeneration. Physiol Rev 2004, 84:209-238.
2. Braun T., Bober E., Rudnicki M.A., Jaenisch R., Arnold H.H. MyoD expression marks the onset of skeletal myogenesis in Myf-5 mutant mice. Development 1994, 120:3083-3092.
3. Buckingham M. Making muscle in mammals. Trends Genet 1992, 8:144-148.
4. Buckingham M. Skeletal muscle formation in vertebrates. Curr Opin Genet Dev 2001, 11:440-448.
5. Buckingham M., Cossu G. Myogenesis in the mouse embryo. Meth Cell Biol 1997, 52:29-52.
6. Aurade F., Pinset C., Chafey P., Gros F., Montarras D. Myf5, MyoD, myogenin and MRF4 myogenic derivatives of the embryonic mesenchymal cell line C3H10T1/2 exhibit the same adult muscle phenotype. Differentiation 1994, 55:185-192.
7. Carvajal J.J., Rigby P.W. Regulation of gene expression in vertebrate skeletal muscle. Exp Cell Res 2010, 316:3014-3018.
8. Lee J.E., Lee J.Y., Wilusz J., Tian B., Wilusz C.J. Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells. PLoS ONE 2010, 5:e11201.
9. Figueroa A., Cuadrado A., Fan J., Atasoy U., Muscat G.E., Munoz-Canoves P., Gorospe M., Munoz A. Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol 2003, 23:4991-5004.
10. van der Giessen K., Di-Marco S., Clair E., Gallouzi I.E. RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation. J Biol Chem 2003, 278:47119-47128.
11. van der Giessen K., Gallouzi I.E. Involvement of transportin 2-mediated HuR import in muscle cell differentiation. Mol Biol Cell 2007, 18:2619-2629.
12. Abdelmohsen K., Kuwano Y., Kim H.H., Gorospe M. Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem 2008, 389:243-255.
13. von Roretz C., Gallouzi I.E. Decoding ARE-mediated decay: is microRNA part of the equation?. J Cell Biol 2008, 181:189-194.
14. Doller A., Pfeilschifter J., Eberhardt W. Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR. Cell Signal 2008, 20:2165-2173.
15. Barreau C., Paillard L., Osborne H.B. AU-rich elements and associated factors: are there unifying principles?. Nucleic Acids Res 2005, 33:7138-7150.
16. Briata P., Forcales S.V., Ponassi M., Corte G., Chen C.Y., Karin M., Puri P.L., Gherzi R. p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts. Mol Cell 2005, 20:891-903.
17. Yamaguchi Y., Oohinata R., Naiki T., Irie K. Stau1 negatively regulates myogenic differentiation in C2C12 cells. Genes Cells 2008, 13:583-592.
18. Gong C., Kim Y.K., Woeller C.F., Tang Y., Maquat L.E. SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev 2009, 23:54-66.
19. Kim Y.K., Furic L., Desgroseillers L., Maquat L.E. Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. Cell 2005, 120:195-208.
20. Keene J.D. Why is Hu where? Shuttling of early-response-gene messenger RNA subsets. Proc Natl Acad Sci USA 1999, 96:5-7.
21. Brennan C.M., Steitz J.A. HuR and mRNA stability. CMLS 2001, 58:266-277.
22. Gallouzi I.E., Brennan C.M., Steitz J.A. Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. Rna 2001, 7:1348-1361.
23. Gallouzi I.E., Steitz J.A. Delineation of mRNA export pathways by the use of cell-permeable peptides. Science 2001, 294:1895-1901.
24. Gherzi R., Trabucchi M., Ponassi M., Gallouzi I.E., Rosenfeld M.G., Briata P. Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation. Cell Death Differ 2010, 17:975-983.
25. Beauchamp P., Nassif C., Hillock S., van der Giessen K., von Roretz C., Jasmin B.J., Gallouzi I.E. The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation. Cell Death Differ 2010, 17:1588-1599.
26. Cuneo A.A., Herrick D., Autieri M.V. Il-19 reduces VSMC activation by regulation of mRNA regulatory factor HuR and reduction of mRNA stability. J Mol Cell Cardiol 2010, 49:647-654.
27. Doller A., Huwiler A., Muller R., Radeke H.H., Pfeilschifter J., Eberhardt W. Protein kinase C{alpha}-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Mol Biol Cell 2007, 18:2137-2148.
28. Kim H.H., Abdelmohsen K., Lal A., Pullmann R., Yang X., Galban S., Srikantan S., Martindale J.L., Blethrow J., Shokat K.M., Gorospe M. Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev 2008, 22:1804-1815.
29. Brennan C.M., Gallouzi I.E., Steitz J.A. Protein ligands to HuR modulate its interaction with target mRNAs in vivo. J Cell Biol 2000, 151:1-14.
30. Rebane A., Aab A., Steitz J.A. Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR. Rna 2004, 10:590-599.
31. Guttinger S., Muhlhausser P., Koller-Eichhorn R., Brennecke J., Kutay U. Transportin2 functions as importin and mediates nuclear import of HuR. Proc Natl Acad Sci USA 2004, 101:2918-2923.
32. Murray T.V., McMahon J.M., Howley B.A., Stanley A., Ritter T., Mohr A., Zwacka R., Fearnhead H.O. A non-apoptotic role for caspase-9 in muscle differentiation. J Cell Sci 2008, 121:3786-3793.
33. Fernando P., Kelly J.F., Balazsi K., Slack R.S., Megeney L.A. Caspase 3 activity is required for skeletal muscle differentiation. Proc Natl Acad Sci USA 2002, 99:11025-11030.
34. Green D.R. Apoptotic pathways: ten minutes to dead. Cell 2005, 121:671-674.
35. Wang J., Lenardo M.J. Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies. J Cell Sci 2000, 113(Pt 5):753-757.
36. Mazroui R., Di Marco S., Clair E., von Roretz C., Tenenbaum S.A., Keene J.D., Saleh M., Gallouzi I.E. Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp 32/PHAP-I regulation of apoptosis. J Cell Biol 2008, 180:113-127.
37. von Roretz C., Gallouzi I.E. Protein kinase RNA/FADD/caspase-8 pathway mediates the proapoptotic activity of the RNA-binding protein human antigen R (HuR). J Biol Chem 2010, 285:16806-16813.
38. Jiang X., Kim H.E., Shu H., Zhao Y., Zhang H., Kofron J., Donnelly J., Burns D., Ng S.C., Rosenberg S., Wang X. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science 2003, 299:223-226.
39. Hill M.M., Adrain C., Duriez P.J., Creagh E.M., Martin S.J. Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes. EMBO J 2004, 23:2134-2145.
40. Kim H.E., Jiang X., Du F., Wang X. PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1. Mol Cell 2008, 30:239-247.
41. Santa-Coloma T.A. Anp32e (Cpd1) and related protein phosphatase 2 inhibitors. Cerebellum (London, England) 2003, 2:310-320.
42. Alisi A., Spaziani A., Anticoli S., Ghidinelli M., Balsano C. PKR is a novel functional direct player that coordinates skeletal muscle differentiation via p38MAPK/AKT pathways. Cell Signal 2008, 20:534-542.
43. Kronfeld-Kinar Y., Vilchik S., Hyman T., Leibkowicz F., Salzberg S. Involvement of PKR in the regulation of myogenesis. Cell Growth Differ 1999, 10:201-212.
44. Salzberg S., Vilchik S., Cohen S., Heller A., Kronfeld-Kinar Y. Expression of a PKR dominant-negative mutant in myogenic cells interferes with the myogenic process. Exp Cell Res 2000, 254:45-54.
45. Williams A.H., Liu N., van Rooij E., Olson E.N. MicroRNA control of muscle development and disease. Curr Opin Cell Biol 2009, 21:461-469.
46. Kang J.S., Krauss R.S. Muscle stem cells in developmental and regenerative myogenesis. Curr Opin Clin Nutr Metab Care 2010, 13:243-248.
47. Gallouzi I.E., Brennan C.M., Stenberg M.G., Swanson M.S., Eversole A., Maizels N., Steitz J.A. HuR binding to cytoplasmic mRNA is perturbed by heat shock. Proc Natl Acad Sci USA 2000, 97:3073-3078.