In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription

Cellular Oncology

Volumn 34, Issue 2, 2011, Pages 131-140

  Puppin, Cinzia ^a   Passon, Nadia ^a   Frasca, Francesco ^a,b   Vigneri, Riccardo ^b   Tomay, Federica ^a   Tomaciello, Stefania ^a   Damante, Giuseppe ^a,c  

^a UNIVERSITY OF UDINE   (Italy)

^b GARIBALDI HOSPITAL   (Italy)

^c SANTA MARIA DELLA MISERICORDIA UNIVERSITY HOSPITAL   (Italy)

Author keywords

Gene expression; Histone acetylation; P73; Periostin; Thyroid tumours

Indexed keywords

HISTONE H3; LYSINE; MESSENGER RNA; PROTEIN P73; TRANSCRIPTION FACTOR RUNX2; TRICHOSTATIN A; VORINOSTAT; CELL ADHESION MOLECULE; DNA BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXE1 PROTEIN, HUMAN; HISTONE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; NUCLEAR PROTEIN; POSTN PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

ARTICLE; CANCER CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EPIGENETICS; GENE ACTIVATION; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROCESSING; THYROID CANCER; ACETYLATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HELA CELL; METABOLISM; MUTATION; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID TUMOR; TUMOR CELL LINE; WESTERN BLOTTING;

ACETYLATION; BLOTTING, WESTERN; CELL ADHESION MOLECULES; CELL LINE, TUMOR; DNA-BINDING PROTEINS; EPIGENOMICS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; HYDROXAMIC ACIDS; LYSINE; MUTATION; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYROID NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 79960902937     PISSN: 22113428     EISSN: 22113436     Source Type: Journal    
DOI: 10.1007/s13402-011-0009-9     Document Type: Article

References (49)

1. S. Takeshita, R. Kikuno, K. Tezuka, E. Amann, Osteoblast-specific factor 2: Cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I. Bioch. J. 294, 271-278 (1993) (Pubitemid 23251940)
2. K. Horiuchi, N. Amizuka, S. Takeshita, H. Takamatsu, M. Katsuura, H. Ozawa, Y. Toyama, L.F. Bonewald, A. Kudo, Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal l igament and increased expression by transforming growth factor beta. J. Bone Min. Res. 14, 1239-1249 (1999) (Pubitemid 29314070)
3. L. Gillan, D. Matei, D.A. Fishman, C.S. Gerbin, B.Y. Karlan, D. D. Chang, Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility. Cancer Res. 62, 5358-5364 (2002) (Pubitemid 35024613)
4. H. Rios, S.V. Koushik, H. Wang, J. Wang, H.M. Zhou, A. Lindsley, R. Rogers, Z. Chen, M. Maeda, A. Kruzynska-Frejtag, J. Q. Feng, S.J. Conway, Periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol. Cell. Biol. 25, 11131-11144 (2005) (Pubitemid 41747153)
5. S.J. Conway, J.D. Molkentin, Periostin as a heterofunctional regulator of cardiac development and disease. Current Genomics 9, 548-555 (2008)
6. Y. Kudo, B.S. Siriwardena, H. Hatano, I. Ogawa, T. Takata, Periostin: Novel diagnostic and therapeutic target for cancer. Hist. Histopath. 22, 1167-1174 (2007) (Pubitemid 47470310)
7. R.G. LeBaron, K.I. Bezverkov, M.P. Zimber, R. Pavelec, J. Skonier, A.F. Purchio, Beta IG-H3, a novel secretory protein inducible by transforming growth factor-beta, is present in normal skin and promotes the adhesion and spreading of dermal fibroblasts in vitro. J. Invest. Dermatol. 104, 844-849 (1995)
8. K. Ruan, S. Bao, G. Ouyang, The multifaceted role of periostin in tumourigenesis. Cell. Mol. Life Sci. 66, 2219-22130 (2009)
9. Y. Kudo, I. Ogawa, S. Kitajima, M. Kitagawa, H. Kawai, P.M. Gaffney, M. Miyauchi, T. Takata, Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer. Cancer Res. 66, 6928-6935 (2006) (Pubitemid 44197667)
10. B.S. Siriwardena, Y. Kudo, I. Ogawa, M. Kitagawa, S. Kitajima, H. Hatano, W.M. Tilakaratne, M. Miyauchi, T. Takata, Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer. Br. J. Cancer 95, 1396-1403 (2006) (Pubitemid 44760092)
11. P. Baril, R. Gangeswaran, P.C. Mahon, K. Caulee, H.M. Kocher, T. Harada, M. Zhu, H. Kalthoff, T. Crnogorac-Jurcevic, N.R. Lemoine, Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: Role of the beta4 integrin and the PI3k pathway. Oncogene 26, 2082-2094 (2007) (Pubitemid 46514745)
12. A. Soltermann, V. Tischler, S. Arbogast, J. Braun, N. Probst-Hensch, W. Weder, H. Moch, G. Kristiansen, Prognostic significance of epithelial- mesenchymal and mesenchymal-epithelial transition protein expression in non-small cell lung cancer. Clin. Cancer Res. 14, 7430-7437 (2008)
13. R. Kalluri, R.A. Weinberg, The basics of epithelial-mesenchymal transition. J. Clin. Invest. 119, 1420-1428 (2009)
14. W. Yan, R. Shao, Transduction of a mesenchyme-specific gene periostin into 293 T cells induces cell invasive activity through epithelial-mesenchymal transformation. J. Biol. Chem. 281, 19700-19708 (2006)
15. L.A. Akslen, A.O. Myking, H. Salvesen, J.E. Varhaug, Prognostic impact of EGF-receptor in papillary thyroid carcinoma. Br. J. Cancer 68, 808-812 (1993) (Pubitemid 23301291)
16. G. Riesco-Eizaguirre, P. Santisteban, New insights in thyroid follicular cell biology and its impact in thyroid cancer therapy. Endocrine-Related Cancer 14, 957-977 (2007) (Pubitemid 351252429)
17. J.A. Fagin, K. Matsuo, A. Karmakar, D.L. Chen, S.H. Tang, H.P. Koeffler, High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J. Clin. Invest. 91, 179-184 (1993) (Pubitemid 23037270)
18. R. Malaguarnera, V. Vella, R. Vigneri, F. Frasca, p53 family proteins in thyroid cancer. Endocrine-Related Cancer 14, 43-60 (2007) (Pubitemid 47521721)
19. C. Puppin, D. Fabbro, M. Dima, C. Di Loreto, E. Puxeddu, S. Filetti, D. Russo, G. Damante, High periostin expression correlates with aggressiveness in papillary thyroid carcinomas. J. Endocrinol. 197, 401-408 (2008) (Pubitemid 351696253)
20. A. Oshima, H. Tanabe, T. Yan, G.N. Lowe, C.A. Kudo, A novel mechanism for the regulation of osteoblast differentiation: Transcription of periostin, a member of the fasciclin I family, is regulated by the bHLH transcription factor, twist. J. Cell. Biochem. 86, 792-804 (2002) (Pubitemid 34839980)
21. R.E. Schweppe, J.P. Klopper, C. Korch, U. Pugazhenthi, M. Benezra, J.A. Knauf, J.A. Fagin, L.A. Marlow, J.A. Copland, R.C. Smallridge, B.R. Haugen, Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. J. Clin. Endocrinol. Metab. 93, 4331-4341 (2008) (Pubitemid 352789529)
22. G. Tell, L. Pellizzari, D. Cimarosti, C. Pucillo, G. Damante, Ref-1 controls pax-8 DNA-binding activity. Bioch. Bioph. Res. Comm. 252, 178-183 (1998) (Pubitemid 28534647)
23. V. Vella, C. Puppin, G. Damante, R. Vigneri, M. Sanfilippo, P. Vigneri, G. Tell, F. Frasca, DeltaNp73alpha inhibits PTEN expression in thyroid cancer cells. Int. J. Cancer 124, 2539-2548 (2009)
24. C. Puppin, F. D'Aurizio, A.V. D'Elia, L. Cesaratto, G. Tell, D. Russo, S. Filetti, E. Ferretti, E. Tosi, T. Mattei, A. Pianta, L. Pellizzari, G. Damante, Effects of histone acetylation on sodium iodide symporter promoter and expression of thyroid-specific transcription factors. J. Endocrinol. 146, 3967-3974 (2005) (Pubitemid 41175768)
25. E. Beillard, N. Pallisgaard, V.H. van der Velden,W. Bi, R. Dee, E. van der Schoot, E. Delabesse, E. Macintyre, E. Gottardi, G. Saglio, F. Watzinger,T. Lion, J.J. vanDongen, P. Hokland, J. Gabert, Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) -a Europe against cancer program. Leukemia 17, 2474-2486 (2003) (Pubitemid 38072587)
26. M.D. Shahbazian, M. Grunstein, Functions of site-specific histone acetylation and deacetylation. Annu. Rev. Bioch. 76, 75-100 (2007)
27. O.J. Rando, Global patterns of histone modifications. Curr. Opin. Genet. Dev. 17, 94-99 (2007) (Pubitemid 46551718)
28. S.J. Berger, The complex language of chromatin regulation during transcription. Nature 447, 407-412 (2007)
29. A. Rada-Iglesias, S. Enroth, A. Ameur, C.M. Koch, G.K. Clelland, P. Respuela-Alonso, S. Wilcox, O.M. Dovey, P.D. Ellis, C.F. Langford, I. Dunham, J. Komorowski, C. Wadelius, Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes. Genome Res. 17, 708-719 (2007) (Pubitemid 46919708)
30. H. Santos-Rosa, R. Schneider, A.J. Bannister, J. Sherriff, B.E. Bernstein,N.C.Emre, S.L. Schreiber, J. Mellor, T.Kouzarides, Active genes are tri-methylated at K4 of histone H3. Nature 419, 407-411 (2002)
31. D.K. Pokholok, C.T. Harbison, S. Levine, M. Cole, N.M. Hannett, T.I. Lee, G.W. Bell, K. Walker, P.A. Rolfe, E. Herbolsheimer, J. Zeitlinger, F. Lewitter, D.K. Gifford, R.A. Young, Genome-wide map of nucleosome acetylation and methylation in yeast. Cell 122, 517-527 (2005) (Pubitemid 41191151)
32. G. Damante, G. Tell, R. Di Lauro, A unique combination of transcription factors controls differentiation of thyroid cells. Progr. Nucl. Acid Res. Mol. Biol. 66, 307-356 (2001)
33. D. Fabbro, C. Di Loreto, C.A. Beltrami, A. Belfiore, R. Di Lauro, G. Damante, Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms. Cancer Res. 54, 4744-4749 (1994) (Pubitemid 24276506)
34. F. Frasca, V. Vella, A. Aloisi, A. Mandarino, E. Mazzon, R. Vigneri, P. Vigneri, p73 tumour-suppressor activity is impaired in human thyroid cancer. Cancer Res. 63, 5829-5837 (2003) (Pubitemid 37187481)
35. L. Perrone, M. Pasca di Magliano, M. Zannini, R. Di Lauro, The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNAbinding independent transcriptional repressor. Biochem Biophys Res Commun. 275, 203-208 (2000) (Pubitemid 30663652)
36. Ø. Fluge, O. Bruland, L.A. Akslen, J.R. Lillehaug, J.E. Varhaug, Gene expression in poorly differentiated papillary thyroid carcinomas. Thyroid 16, 161-175 (2006)
37. K.P. Nightingale, S. Gendreizig, D.A. White, C. Bradbury, F. Hollfelder, B.M. Turner, Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation. J. Biol. Chem. 282, 4408-4416 (2007) (Pubitemid 47100929)
38. Z. Marinova, Y. Leng, P. Leeds, D.M. Chuang, Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons, Neuropharmacology 2010 Oct 1. [Epub ahead of print]
39. W. Luo, A.R. Karpf, K.K. Deeb, J.R. Muindi, C.D. Morrison, C.S. Johnson, D.L. Trump, Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. Cancer Res. 70, 5953-5962 (2010)
40. X. Zeng, H. Lee, Q. Zhang, H. Lu, P300 does not require its acetylase activity to stimulate p73 function. J. Biol. Chem. 276, 48-52 (2001) (Pubitemid 32050287)
41. P. Finzer, A. Krueger, M. Stöhr, D. Brenner, U. Soto, C. Kuntzen, P.H. Krammer, F. Rösl, HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway. Oncogene 23, 4807-4817 (2004) (Pubitemid 38932153)
42. J. Zawacka-Pankau, A. Kostecka, A. Sznarkowska, E.A. Hedström Kawiak, p73 tumor suppressor protein: A close relative of p53 not only in structure but also in anti-cancer approach? Cell Cycle 9, 720- 728 (2010)
43. L. Roger, L. Jullien, V. Gire, P. Roux, Gain of oncogenic function of p53 mutants regulates E-cadherin expression uncoupled from cell invasion in colon cancer cells. J. Cell Science 123, 1295-1305 (2010)
44. S.P.Wang,W.L.Wang, Y.L. Chang, C.T.Wu, Y.C. Chao, S.H. Kao,A. Yuan, C.W. Lin, S.C. Yang, W.K. Chan, K.C. Li, T.M. Hong, P.C. Yang, p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat. Cell Biol. 11, 694-704 (2009)
45. S.O. Lim, H. Kim, G. Jung, p53 inhibits tumour cell invasion via the degradation of snail protein in hepatocellular carcinoma. FEBS Letters 584, 2231-2236 (2010)
46. M.J. Sequeira, J.M. Morga, D. Fuhrer, M.H.Wheeler, B. Jasani, M. Ludgate, Thyroid transcription factor-2 gene expression in benign and malignant thyroid lesions. Thyroid 11, 995-1001 (2001) (Pubitemid 33107910)
47. D. Nonaka, Y. Tang, L. Chiriboga, M. Rivera, R. Ghossein, Diagnostic utility of thyroid transcription factors Pax8 and TTF-2 (FoxE1) in thyroid epithelial neoplasms. Modern Pathology 21, 192-200 (2008) (Pubitemid 351172171)
48. I. Landa, S. Ruiz-Llorente, C. Montero-Conde, L. Inglada-Pérez, F. Schiavi et al., The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/ USF2 transcription factors. PLoS Genet. 5, 1000637 (2009)
49. T. Joyce, D. Cantarella, C. Isella, E. Medico, A. Pintzas, A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by largescale microarray analysis. Clin. Exp. Metastasis 26, 569-587 (2009)