Human trophoblast in trisomy 21: A model for cell-cell fusion dynamic investigation

Advances in Experimental Medicine and Biology

Volumn 950, Issue , 2011, Pages 103-112

  Malassiné, André ^a   Pidoux, Guillaume ^a   Gerbaud, Pascale ^a   Frendo, Jean Louis ^a   Evain Brion, Danièle ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43; COPPER ZINC SUPEROXIDE DISMUTASE; PROTEIN ZO1; SYNCYTIN 1 PROTEIN; SYNCYTIN 2 PROTEIN; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; PLACENTA PROTEIN; SYNCYTIN; SYNCYTIN 2 PROTEIN, HUMAN; VIRUS ENVELOPE PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELL FUSION; CHROMOSOME 21; FRD GENE; GENE; HERV W GENE; HUMAN; IN VITRO STUDY; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNCYTIOTROPHOBLAST; TRISOMY 21; TROPHOBLAST; VIRUS ENVELOPE; DOWN SYNDROME; PATHOLOGY; PHYSIOLOGY; REVIEW;

HUMAN ENDOGENOUS RETROVIRUS W;

CELL DIFFERENTIATION; CELL FUSION; DOWN SYNDROME; GENE PRODUCTS, ENV; HUMANS; PREGNANCY PROTEINS; TROPHOBLASTS;

EID: 79960900304     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-94-007-0782-5_4     Document Type: Article

References (41)

1. Benirschke K, Kaufmann P (2000) Pathology of the placenta. Springer, New York, NY
2. Malassine A, Frendo JL, Evain-Brion D (2003) A comparison of placental development and endocrine functions between the human and mouse model. Hum Reprod Update 9:531-539 (Pubitemid 38072146)
3. Evain-Brion D, Malassine A (2003) Human placenta as an endocrine organ. Growth Horm IGF Res 13(Suppl A):S34-S37 (Pubitemid 37161655)
4. Alsat E, Mirlesse V, Fondacci C, et al. (1991) Parathyroid hormone increases epidermal growth factor receptors in cultured human trophoblastic cells from early and term placenta. J Clin Endocrinol Metab 73:288-295 (Pubitemid 21921871)
5. Kliman HJ, Nestler JE, Sermasi E, et al. (1986) Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology 118:1567-1582 (Pubitemid 16078536)
6. Getsios S, MacCalman CD (2003) Cadherin-11 modulates the terminal differentiation and fusion of human trophoblastic cells in vitro. Dev Biol 257:41-54 (Pubitemid 36438643)
7. Dalton P, Christian HC, Redman CW, et al. (2007) Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells - implication for placental cell fusion. FEBS J 274:2715-2727 (Pubitemid 46800542)
8. Huppertz B, Bartz C, Kokozidou M (2006) Trophoblast fusion: fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion. Micron 37:509-517 (Pubitemid 44037407)
9. Frendo JL, Cronier L, Bertin G, et al. (2003) Involvement of connexin 43 in human trophoblast cell fusion and differentiation. J Cell Sci 116:3413-3421 (Pubitemid 37038988)
10. Pidoux G, Gerbaud P, Gnidehou S, et al. (2010) ZO-1 is involved in trophoblastic cell differentiation in human placenta. Am J Physiol Cell Physiol 298:C1517-C1526
11. Frendo JL, Olivier D, Cheynet V, et al. (2003) Direct involvement of HERV-W Env glycoprotein in human trophoblast cell fusion and differentiation. Mol Cell Biol 23:3566-3574 (Pubitemid 36539189)
12. Blaise S, de Parseval N, Benit L, et al. (2003) Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution. Proc Natl Acad Sci USA 100:13013-13018 (Pubitemid 37340017)
13. Blond JL, Lavillette D, Cheynet V, et al. (2000) An envelope glycoprotein of the human endogenous retrovirus HERV-W is expressed in the human placenta and fuses cells expressing the type D mammalian retrovirus receptor. J Virol 74:3321-3329 (Pubitemid 30143757)
14. Mi S, Lee X, Li X, et al. (2000) Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis. Nature 403:785-789 (Pubitemid 30111841)
15. de Parseval N, Heidmann T (2005) Human endogenous retroviruses: from infectious elements to human genes. Cytogen Genome Res 110:318-332 (Pubitemid 41159909)
16. Mallet F, Bouton O, Prudhomme S, et al. (2004) The endogenous retroviral locus ERVWE1 is a bona fide gene involved in hominoid placental physiology. Proc Natl Acad Sci USA 101:1731-1736 (Pubitemid 38234222)
17. Gimenez J, Montgiraud C, Oriol G, et al. (2009) Comparative methylation of ERVWE1/syncytin-1 and other human endogenous retrovirus LTRs in placenta tissues. DNA Res 16:195-211
18. Liang CY,Wang LJ, Chen CP, et al. (2010) GCM1 regulation of the expression of Syncytin 2 and its cognate receptor MFSD2A in human placenta. Biol Reprod 83:387-395
19. Blaise S, de Parseval N, Heidmann T (2005) Functional characterization of two newly identified Human Endogenous Retrovirus coding envelope genes. Retrovirology 2:19
20. Kjeldbjerg AL, Villesen P, Aagaard L, et al. (2008) Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution. BMC Evol Biol 8:266
21. Muir A, Lever AM, Moffett A (2006) Human endogenous retrovirus-W envelope (syncytin) is expressed in both villous and extravillous trophoblast populations. J Gen Virol 87:2067-2071 (Pubitemid 43985891)
22. Malassine A, Lavialle C, Frendo JL, et al. (2010) Syncytins in normal and pathological placentas. In: Lever AML, Jeang KT, Berkhout B (eds.) Recent advances in Human Retroviruses. World Scientific, pp. 243-270
23. Malassine A, Handschuh K, Tsatsaris V, et al. (2005) Expression of HERV-W Env glycoprotein (syncytin) in the extravillous trophoblast of first trimester human placenta. Placenta 26:556-562 (Pubitemid 40916308)
24. Malassine A, Frendo JL, Blaise S, et al. (2008) Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta. Retrovirology 5:6
25. Malassine A, Frendo JL, Evain-Brion D (2010) Trisomy 21- affected placentas highlight prerequisite factors for human trophoblast fusion and differentiation. Int J Dev Biol 54:475-482
26. Esnault C, Priet S, Ribet D, et al. (2008) A placenta-specific receptor for the fusogenic, endogenous retrovirusderived, human syncytin-2. Proc Natl Acad Sci USA 105:17532-17537
27. Kudaka W, Oda T, Jinno Y, et al. (2008) Cellular localization of placenta-specific human endogenous retrovirus (HERV) transcripts and their possible implication in pregnancy-induced hypertension. Placenta 29:282-289
28. Vargas A, Moreau J, Landry S, et al. (2009) Syncytin-2 plays an important role in the fusion of human trophoblast cells. J Mol Biol 392:301-318
29. Qureshi F, Jacques SM, Johnson MP, et al. (1997) Trisomy 21 placentas: histopathological and immunohistochemical findings using proliferating cell nuclear antigen. Fetal Diagn Ther 12:210-215 (Pubitemid 27420426)
30. Oberweis D, Gillerot Y, Koulischer L, et al. (1983) The placenta in trisomy in the last trimester of pregnancy. J Gynecol Obstet Biol Reprod (Paris) 12:345-349 (Pubitemid 13052053)
31. Roberts L, Sebire NJ, Fowler D, et al. (2000) Histomorphological features of chorionic villi at 10-14 weeks of gestation in trisomic and chromosomally normal pregnancies. Placenta 21:678-683
32. Forbes K, Westwood M, Baker PN, et al. (2008) Insulin-like growth factor I and II regulate the life cycle of trophoblast in the developing human placenta. Am J Physiol Cell Physiol 294:C1313-C1322
33. Massin N, Frendo JL, Guibourdenche J, et al. (2001) Defect of syncytiotrophoblast formation and human chorionic gonadotropin expression in Downs syndrome. Placenta 22(Suppl A):S93-S97 (Pubitemid 33712466)
34. Pidoux G, Guibourdenche J, Frendo JL, et al. (2004) Impact of trisomy 21 on human trophoblast behaviour and hormonal function. Placenta 25(Suppl A):S79-S84 (Pubitemid 38514961)
35. Frendo JL, Guibourdenche J, Pidoux G, et al. (2004) Trophoblast production of a weakly bioactive human chorionic gonadotropin in trisomy 21-affected pregnancy. J Clin Endocrinol Metab 89:727-732 (Pubitemid 38269884)
36. Frendo JL, Therond P, Bird T, et al. (2001) Overexpression of copper zinc superoxide dismutase impairs human trophoblast cell fusion and differentiation. Endocrinology 142:3638-3648 (Pubitemid 32681775)
37. Frendo JL, Therond P, Guibourdenche J, et al. (2002) Implication of copper zinc superoxide dismutase (SOD-1) in human placenta development. Ann NY Acad Sci 973:297-301 (Pubitemid 36125025)
38. Pidoux G, Gerbaud P, Marpeau O, et al. (2007) Human placental development is impaired by abnormal human chorionic gonadotropin signaling in trisomy 21 pregnancies. Endocrinology 148:5403-5413 (Pubitemid 350012653)
39. Dimon-Gadal S, Gerbaud P, Keryer G, et al. (1998) In vitro effects of oxygen-derived free radicals on type I and type II cAMP-dependent protein kinases. J Biol Chem 273:22833-22840 (Pubitemid 28399859)
40. Pidoux G, Tasken K (2010) Specificity and spatial dynamics of protein kinase A signaling organized by A-kinaseanchoring proteins. J Mol Endocrinol 44:271-284
41. Hemberger M, Udayashankar R, Tesar P, et al. (2010) ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta. Hum Mol Genet 19:2456-2467