Synthesis and biological evaluation of piperamide analogues as HDAC inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 16, 2011, Pages 4844-4846

  Luo, Yu ^a   Liu, Hao Min ^a   Su, Ming Bo ^b   Sheng, Li ^b   Zhou, Yu Bo ^b   Li, Jia ^b   Lu, Wei ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

HDAC; Piperlonguminine; Refrofractamide A

Indexed keywords

AMIDE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; PIPERLONGUMININE; RECOMBINANT ENZYME; REFROFRACTAMIDE A; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

AMIDES; BENZODIOXOLES; DIOXOLANES; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; MOLECULAR STRUCTURE; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960896421     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.06.046     Document Type: Article

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