Expression of CD24 in cholangiocarcinoma cells is associated with disease progression and reduced patient survival

International Journal of Oncology

Volumn 39, Issue 4, 2011, Pages 873-881

  Keeratichamroen, Siriporn ^a,b   Leelawat, Kawin ^c,d   Thongtawee, Taweesak ^c   Narong, Siriluck ^c   Aegem, Umaad ^c   Tujinda, Supathip ^c   Praditphol, Niphon ^c   Tohtong, Rutaiwan ^a  

^a Mahidol University ^*  (Thailand)

^b Krung Thep Maha Nakhon   (Thailand)

^c RAJAVITHI HOSPITAL   (Thailand)

^d RANGSIT UNIVERSITY   (Thailand)

Author keywords

CD24; Cholangiocarcinoma; Invasion; Metastasis; Survival

Indexed keywords

CD24 ANTIGEN; MATRILYSIN; SMALL INTERFERING RNA;

ADULT; ANTIGEN EXPRESSION; ARTICLE; BILE DUCT CARCINOMA; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CANCER PATIENT; CANCER RESISTANCE; CANCER SURVIVAL; CELL FUNCTION; CELL ISOLATION; CELL MIGRATION; CELL MOTILITY; CELL SELECTION; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPH NODE METASTASIS; MAGNETIC ACTIVATED CELL SORTING; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS;

ANTIGENS, CD24; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CELL ADHESION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL MOVEMENT; CHOLANGIOCARCINOMA; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; HUMANS; LYMPHATIC METASTASIS; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASE 9; MULTIVARIATE ANALYSIS; NEOPLASM INVASIVENESS; PARAFFIN EMBEDDING; PROGNOSIS;

EID: 79960862974     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1088     Document Type: Article

References (28)

1. Sripa B and Pairojkul C: Cholangiocarcinoma: lessons from Thailand. Curr Opin Gastroenterol 24: 349-356, 2008. (Pubitemid 351535894)
2. Akoad M and Jenkins R: Proximal biliary malignancy. Surg Clin North Am 88: 1409-1428, x-xi, 2008.
3. Sano T, Shimada K, Sakamoto Y, Ojima H, Esaki M and Kosuge T: Prognosis of perihilar cholangiocarcinoma: hilar bile duct cancer versus intrahepatic cholangiocarcinoma involving the hepatic hilus. Ann Surg Oncol 15: 590-599, 2008.
4. Shimada K, Sano T, Sakamoto Y, Esaki M, Kosuge T and Ojima H: Clinical impact of the surgical margin status in hepatectomy for solitary mass-forming type intrahepatic cholangiocarcinoma without lymph node metastases. J Surg Oncol 96: 160-165, 2007. (Pubitemid 47264820)
5. Tucek S, Tomasek J, Halamkova J, et al: Bile duct malignancies. Klin Onkol 23: 231-241, 2010.
6. Kristiansen G, Sammar M and Altevogt P: Tumour biological aspects of CD24, a mucin-like adhesion molecule. J Mol Histol 35: 255-262, 2004. (Pubitemid 40585311)
7. Redondo P, Garcia-Foncillas J, Okroujnov I, De Felipe I and Quintanilla E: CD24 expression on human keratinocytes. Exp Dermatol 7: 175-178, 1998. (Pubitemid 28419407)
8. Lee HJ, Choe G, Jheon S, Sung SW, Lee CT and Chung JH: CD24, a novel cancer biomarker, predicting disease-free survival of non-small cell lung carcinomas: a retrospective study of prognostic factor analysis from the viewpoint of forthcoming (seventh) new TNM classification. J Thorac Oncol 5: 649-657, 2010.
9. Lee JH, Kim SH, Lee ES and Kim YS: CD24 overexpression in cancer development and progression: a meta-analysis. Oncol Rep 22: 1149-1156, 2009.
10. Agrawal S, Kuvshinoff BW, Khoury T, et al: CD24 expression is an independent prognostic marker in cholangiocarcinoma. J Gastrointest Surg 11: 445-451, 2007.
11. Su MC, Hsu C, Kao HL and Jeng YM: CD24 expression is a prognostic factor in intrahepatic cholangiocarcinoma. Cancer Lett 235: 34-39, 2006.
12. Rattanasinganchan P, Leelawat K, Treepongkaruna SA, et al: Establishment and characterization of a cholangiocarcinoma cell line (RMCCA-1) from a Thai patient. World J Gastroenterol 12: 6500-6506, 2006. (Pubitemid 44742585)
13. Baumann P, Cremers N, Kroese F, et al: CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis. Cancer Res 65: 10783-10793, 2005. (Pubitemid 41715227)
14. Senner V, Sturm A, Baur I, Schrell UH, Distel L and Paulus W: CD24 promotes invasion of glioma cells in vivo. J Neuropathol Exp Neurol 58: 795-802, 1999. (Pubitemid 29372834)
15. Egeblad M and Werb Z: New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2: 161-174, 2002. (Pubitemid 37328786)
16. Sternlicht MD and Werb Z: How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 17: 463-516, 2001. (Pubitemid 33096184)
17. Ikenaga N, Ohuchida K, Mizumoto K, et al: Characterization of CD24 expression in intraductal papillary mucinous neoplasms and ductal carcinoma of the pancreas. Hum Pathol 41: 1466-1474, 2010.
18. Yang XR, Xu Y, Yu B, et al: CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery. Clin Cancer Res 15: 5518-5527, 2009.
19. Sagiv E, Starr A, Rozovski U, et al: Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA. Cancer Res 68: 2803-2812, 2008. (Pubitemid 351556279)
20. Yilmaz M and Christofori G: Mechanisms of motility in metastasizing cells. Mol Cancer Res 8: 629-642, 2010.
21. Kim HJ, Kim JB, Lee KM, et al: Isolation of CD24(high) and CD24(low/-) cells from MCF-7: CD24 expression is positively related with proliferation, adhesion and invasion in MCF-7. Cancer Lett 258: 98-108, 2007. (Pubitemid 47600499)
22. Ahmed MA, Jackson D, Seth R, et al: CD24 is upregulated in inflammatory bowel disease and stimulates cell motility and colony formation. Inflamm Bowel Dis 16: 795-803, 2010.
23. Ii M, Yamamoto H, Adachi Y, Maruyama Y and Shinomura Y: Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. Exp Biol Med (Maywood) 231: 20-27, 2006. (Pubitemid 43063974)
24. Noe V, Fingleton B, Jacobs K, et al: Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J Cell Sci 114: 111-118, 2001. (Pubitemid 32120080)
25. Yamashita K, Mori M, Shiraishi T, Shibuta K and Sugimachi K: Clinical significance of matrix metalloproteinase-7 expression in esophageal carcinoma. Clin Cancer Res 6: 1169-1174, 2000. (Pubitemid 30159381)
26. Jones LE, Humphreys MJ, Campbell F, Neoptolemos JP and Boyd MT: Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival. Clin Cancer Res 10: 2832-2845, 2004. (Pubitemid 38509163)
27. Itatsu K, Zen Y, Yamaguchi J, et al: Expression of matrix metalloproteinase 7 is an unfavorable postoperative prognostic factor in cholangiocarcinoma of the perihilar, hilar, and extrahepatic bile ducts. Hum Pathol 39: 710-719, 2008.
28. Leelawat K, Narong S, Wannaprasert J and Ratanashu-ek T: Prospective study of MMP7 serum levels in the diagnosis of cholangiocarcinoma. World J Gastroenterol 16: 4697-4703, 2010.