TGF-β1, EGF and FGF4 synergistically induce differentiation of the seminoma cell line TCam-2 into a cell type resembling mixed non-seminoma

International Journal of Andrology

Volumn 34, Issue 4 PART 2, 2011, Pages

  Nettersheim, D ^a   Gillis, A J M ^b   Looijenga, L H J ^b   Schorle, H ^a  

^a UNIVERSITY OF BONN   (Germany)

^b JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

Author keywords

Cancer; Carcinoma in situ testis; Cell cycle; Cell differentiation; CIS testis; Gene expression; Germ cells

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; BONE MORPHOGENETIC PROTEIN; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 4; SMAD PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TEAD4; TRANSCRIPTION FACTOR YAP1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CARCINOMA IN SITU; CELL DIFFERENTIATION; CELL TYPE; CHORIOCARCINOMA; CONTROLLED STUDY; DOWN REGULATION; EMBRYONAL CARCINOMA; GENETIC MARKER; GERM CELL TUMOR; GIANT CELL; HISTONE MODIFICATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; MALE; MALIGNANT TRANSFORMATION; NONSEMINOMA; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEMINOMA; SIGNAL TRANSDUCTION; TERATOMA; TESTIS TUMOR; YOLK SAC TUMOR;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BIOLOGICAL MARKERS; BONE MORPHOGENETIC PROTEIN RECEPTORS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHORIOCARCINOMA; DNA-BINDING PROTEINS; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 4; GIANT CELLS; HISTONES; HUMANS; MALE; MUSCLE PROTEINS; NEOPLASMS, GERM CELL AND EMBRYONAL; POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; SEMINOMA; SIGNAL TRANSDUCTION; SMAD PROTEINS; TESTICULAR NEOPLASMS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MICROENVIRONMENT;

EID: 79960859328     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2011.01172.x     Document Type: Article

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