메뉴 건너뛰기




Volumn 41, Issue 4, 2011, Pages 673-683

The effects of p53 inhibition using pifithrin-α on acute necrotizing pancreatitis in rats;Pifithrin-α ile oluşturulan p53 inhibisyonunun sıçanlarda akut nekrotizan pankreatite etkileri

Author keywords

Acute pancreatitis; P53; Pifithrin

Indexed keywords

ALANINE AMINOTRANSFERASE; AMYLASE; CALCIUM; GLYCODEOXYCHOLIC ACID; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MALONALDEHYDE; MYELOPEROXIDASE; OXYGEN; PIFITHRIN ALPHA; PROTEIN P53; SODIUM CHLORIDE; UREA;

EID: 79960826259     PISSN: 13000144     EISSN: None     Source Type: Journal    
DOI: 10.3906/sag-1007-984     Document Type: Article
Times cited : (6)

References (39)
  • 1
    • 0034004844 scopus 로고    scopus 로고
    • Frequency and time course of pancreatic and extra pancreatic bacterial infection in experimental pancreatitis in rats
    • Schwarz M, Thomson J, Meyer H, Büchler MW, Beger HG. Frequency and time course of pancreatic and extra pancreatic bacterial infection in experimental pancreatitis in rats. Surgery 2000; 127: 427-32.
    • (2000) Surgery , vol.127 , pp. 427-432
    • Schwarz, M.1    Thomson, J.2    Meyer, H.3    Büchler, M.W.4    Beger, H.G.5
  • 2
    • 0032983529 scopus 로고    scopus 로고
    • Pathophysiology of pancreatitis
    • Role of cytokines and inflammatory mediators
    • Saluja AK, Steer ML. Pathophysiology of pancreatitis. Role of cytokines and inflammatory mediators. Digestion 1999; 60 (Suppl 1): 27-33.
    • (1999) Digestion , vol.60 , Issue.SUPPL. 1 , pp. 27-33
    • Saluja, A.K.1    Steer, M.L.2
  • 3
    • 0025258919 scopus 로고
    • Pancreatic ischemia in experimental acute pancreatitis: Mechanism, significance and therapy
    • Klar E, Messmer K, Warshaw, Herfarth C. Pancreatic ischemia in experimental acute pancreatitis: mechanism, significance and therapy. Br J Surg 1990; 77: 1205-10.
    • (1990) Br J Surg , vol.77 , pp. 1205-1210
    • Klar, E.1    Messmer, K.2    Warshaw3    Herfarth, C.4
  • 4
    • 0035663404 scopus 로고    scopus 로고
    • The effects of dopexamine on acute necrotizing pancreatitis in rats
    • Alhan E, Kücüktülü U, Erçin C, Deger O, Çicek R. The effects of dopexamine on acute necrotizing pancreatitis in rats. Eur J Surg 2001; 167: 761-66.
    • (2001) Eur J Surg , vol.167 , pp. 761-766
    • Alhan, E.1    Kücüktülü, U.2    Erçin, C.3    Deger, O.4    Çicek, R.5
  • 5
    • 0031984853 scopus 로고    scopus 로고
    • The role of cytokines in the pathogenesis of acute pancreatitis
    • Norman J. The role of cytokines in the pathogenesis of acute pancreatitis. Am J Surg 1998; 1175: 76-83.
    • (1998) Am J Surg , vol.1175 , pp. 76-83
    • Norman, J.1
  • 7
    • 0022643293 scopus 로고
    • Hemodynamic data pattern in patients with acute pancreatitis
    • Beger HG, Bittner R, Büchler M. Hemodynamic data pattern in patients with acute pancreatitis. Gastroenterology 1986; 90: 74-9.
    • (1986) Gastroenterology , vol.90 , pp. 74-79
    • Beger, H.G.1    Bittner, R.2    Büchler, M.3
  • 8
    • 0001275773 scopus 로고    scopus 로고
    • Does pancreatic necrosis predict severity in patients with acute necrotizing pancreatitis?
    • Banks PA, Tenner S, Noordhoek EC, Sica G, Feng S, Zinner M. Does pancreatic necrosis predict severity in patients with acute necrotizing pancreatitis? Digestion 1996; 57: 218-23.
    • (1996) Digestion , vol.57 , pp. 218-223
    • Banks, P.A.1    Tenner, S.2    Noordhoek, E.C.3    Sica, G.4    Feng, S.5    Zinner, M.6
  • 10
    • 0029965280 scopus 로고    scopus 로고
    • FADD/Mort1 is a common mediator of CD95 (Fas/APO1) and tumor necrosis factor receptor-induced apoptosis
    • Chinaiyan AM, Teper CG, Seldin MF. FADD/Mort1 is a common mediator of CD95 (Fas/APO1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem 1996; 271: 4961-65.
    • (1996) J Biol Chem , vol.271 , pp. 4961-4965
    • Chinaiyan, A.M.1    Teper, C.G.2    Seldin, M.F.3
  • 12
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 2001; 15: 2922-33.
    • (2001) Genes Dev , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 13
    • 0033396491 scopus 로고    scopus 로고
    • Fas ligand induced apoptosis
    • Nagata S. Fas ligand induced apoptosis. Annu Rev Genet 1999; 33: 29-55.
    • (1999) Annu Rev Genet , vol.33 , pp. 29-55
    • Nagata, S.1
  • 14
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanism of caspase regulation during apoptosis
    • Riedl SJ, Shi Y. Molecular mechanism of caspase regulation during apoptosis. Mol Cell Biol 2004; 5: 897-907.
    • (2004) Mol Cell Biol , vol.5 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 15
    • 0033521143 scopus 로고    scopus 로고
    • Conformational and molecular basis for induction of apoptosis by a p53 C-terminal peptide in human cancer cells
    • Kim AL, Raffo AJ, Brand-Rauf PW, Pincus MR, Monaco R, Abarzua P et al. Conformational and molecular basis for induction of apoptosis by a p53 C-terminal peptide in human cancer cells. J Biol Chem 1999; 274: 34924-31.
    • (1999) J Biol Chem , vol.274 , pp. 34924-34931
    • Kim, A.L.1    Raffo, A.J.2    Brand-Rauf, P.W.3    Pincus, M.R.4    Monaco, R.5    Abarzua, P.6
  • 16
    • 0038359753 scopus 로고    scopus 로고
    • Involvement of cytochrome c release and caspase-3 activation in the oxidative stress-induced apoptosis in human tendon fibroblasts
    • Yuan J, Murrell GA, Trickett A, Wang MX. Involvement of cytochrome c release and caspase-3 activation in the oxidative stress-induced apoptosis in human tendon fibroblasts. Biochim Biophys Acta. 2003; 1641: 35-41.
    • (2003) Biochim Biophys Acta. , vol.1641 , pp. 35-41
    • Yuan, J.1    Murrell, G.A.2    Trickett, A.3    Wang, M.X.4
  • 17
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • Karin M, Lin A. NF-kappaB at the crossroads of life and death. Nat Immunol 2002; 3: 221-27.
    • (2002) Nat Immunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 18
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: Roles in cell survival and oncogenesis
    • Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22: 8590-607.
    • (2003) Oncogene , vol.22 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.2    Adams, J.M.3
  • 20
    • 0141814999 scopus 로고    scopus 로고
    • Oxidative stress induces nuclear loss of DNA repair proteins Ku 70 and Ku 80 and apoptosis in pancreatic acinar AR42J cells
    • Song SJ, Lim JW, Kim H, Morio T, Kim KH. Oxidative stress induces nuclear loss of DNA repair proteins Ku 70 and Ku 80 and apoptosis in pancreatic acinar AR42J cells. J Biol Chem 2003; 278: 36676-87.
    • (2003) J Biol Chem , vol.278 , pp. 36676-36687
    • Song, S.J.1    Lim, J.W.2    Kim, H.3    Morio, T.4    Kim, K.H.5
  • 21
    • 0034942714 scopus 로고    scopus 로고
    • Acute pancreatitis signals activation of apoptosisassociated and survival genes in mice
    • Gomez G, Lee HM, He Q, Englander EW, Uchida T, Greeley GH Jr. Acute pancreatitis signals activation of apoptosisassociated and survival genes in mice. Exp Biol Med 2001; 226: 692-700.
    • (2001) Exp Biol Med , vol.226 , pp. 692-700
    • Gomez, G.1    Lee, H.M.2    He, Q.3    Englander, E.W.4    Uchida, T.5    Greeley Jr., G.H.6
  • 22
    • 0034856314 scopus 로고    scopus 로고
    • Lysophosphatidylcholine activates transcription factor NF-kappaB and AP-1 in AR42J cells
    • Masamune A, Sakai Y, Yoshida M, Satoh A, Satoh K, Shimosegawa T. Lysophosphatidylcholine activates transcription factor NF-kappaB and AP-1 in AR42J cells. Dig Dis Sci 2001; 46: 1871-81.
    • (2001) Dig Dis Sci , vol.46 , pp. 1871-1881
    • Masamune, A.1    Sakai, Y.2    Yoshida, M.3    Satoh, A.4    Satoh, K.5    Shimosegawa, T.6
  • 23
    • 0029841658 scopus 로고    scopus 로고
    • The role of neutrophils and plateletactivating factor in mediating experimental pancreatitis
    • Sandoval D, Gukovskaya A, Reavey P, Gukovsky S, Sisk A, Braquet P et al. The role of neutrophils and plateletactivating factor in mediating experimental pancreatitis. Gastroenterology 1996; 111: 1081-91.
    • (1996) Gastroenterology , vol.111 , pp. 1081-1091
    • Sandoval, D.1    Gukovskaya, A.2    Reavey, P.3    Gukovsky, S.4    Sisk, A.5    Braquet, P.6
  • 24
    • 0033860040 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha triggers antiapoptotic mechanisms in rat pancreatic cells through pancreatitis-associated protein I activation
    • Malka D, Vasseur S, Bödeker H, Ortiz EM, Dusetti NJ, Verrando P et al. Tumor necrosis factor alpha triggers antiapoptotic mechanisms in rat pancreatic cells through pancreatitis-associated protein I activation. Gastroenterology 2000; 119: 816-28.
    • (2000) Gastroenterology , vol.119 , pp. 816-828
    • Malka, D.1    Vasseur, S.2    Bödeker, H.3    Ortiz, E.M.4    Dusetti, N.J.5    Verrando, P.6
  • 25
    • 0033961443 scopus 로고    scopus 로고
    • Role of p53 family members in apoptosis
    • Sheikh MS, Fornace AJ. Role of p53 family members in apoptosis. J Cell Physiol 2000; 182: 171-81.
    • (2000) J Cell Physiol , vol.182 , pp. 171-181
    • Sheikh, M.S.1    Fornace, A.J.2
  • 27
    • 0037387947 scopus 로고    scopus 로고
    • Inhibition of p53 protects liver tissue against endotoxininduced apoptotic and necrotic cell death
    • Schafer T, Scheuer C, Roenerk K, Menger MD, Vollmar B. Inhibition of p53 protects liver tissue against endotoxininduced apoptotic and necrotic cell death. FASEB J 2003; 17: 660-67.
    • (2003) FASEB J , vol.17 , pp. 660-667
    • Schafer, T.1    Scheuer, C.2    Roenerk, K.3    Menger, M.D.4    Vollmar, B.5
  • 28
    • 0026528816 scopus 로고
    • A better model of acute pancreatitis for evaluating therapy
    • Schmidt J, Rattner MD, Lewandrowski K. A better model of acute pancreatitis for evaluating therapy. Ann Surg 1992; 215: 44-56.
    • (1992) Ann Surg , vol.215 , pp. 44-56
    • Schmidt, J.1    Rattner, M.D.2    Lewandrowski, K.3
  • 29
    • 0037374174 scopus 로고    scopus 로고
    • Noninvasive in vivo assessment of the pancreatic microcirculation: Orthogonal polarization spectral imaging
    • Dobschuetz E, Biberthaler P, Mussack T, Langer S, Messmer K, Hoffmann T. Noninvasive in vivo assessment of the pancreatic microcirculation: orthogonal polarization spectral imaging. Pancreas 2003; 26: 139-43.
    • (2003) Pancreas , vol.26 , pp. 139-143
    • Dobschuetz, E.1    Biberthaler, P.2    Mussack, T.3    Langer, S.4    Messmer, K.5    Hoffmann, T.6
  • 30
    • 0036154973 scopus 로고    scopus 로고
    • A novel therapeutic strategy for attenuating neutrophil-mediated lung injury in vivo
    • Sookhal S, Wang JJ, McCourt M, Kwan W, Bouchier DH, Redmond P. A novel therapeutic strategy for attenuating neutrophil-mediated lung injury in vivo. Ann Surg 2002; 235: 283-91.
    • (2002) Ann Surg , vol.235 , pp. 283-291
    • Sookhal, S.1    Wang, J.J.2    McCourt, M.3    Kwan, W.4    Bouchier, D.H.5    Redmond, P.6
  • 31
    • 0023915694 scopus 로고
    • When should treatment of acute experimental pancreatitis be started?
    • The early phase of bile-induced acute pancreatitis
    • Lankisch PG, Pohl U, Otto J, Rahlf G. When should treatment of acute experimental pancreatitis be started? The early phase of bile-induced acute pancreatitis. Res Exp Med 1988; 188: 123-29.
    • (1988) Res Exp Med , vol.188 , pp. 123-129
    • Lankisch, P.G.1    Pohl, U.2    Otto, J.3    Rahlf, G.4
  • 32
    • 0037093812 scopus 로고    scopus 로고
    • Fas (CD95/APO-1) and Fas ligand expression in normal pancreas and pancreatic tumors
    • Implications for immune privilege and immune escape
    • Bernstorff WV, Glickman JN, Odze RD, Farraye FA, Joo HG, Goedegebuure PS, Eberlein TJ. Fas (CD95/APO-1) and Fas ligand expression in normal pancreas and pancreatic tumors. Implications for immune privilege and immune escape. Cancer 2002; 94: 2552-2560.
    • (2002) Cancer , vol.94 , pp. 2552-2560
    • Bernstorff, W.V.1    Glickman, J.N.2    Odze, R.D.3    Farraye, F.A.4    Joo, H.G.5    Goedegebuure, P.S.6    Eberlein, T.J.7
  • 33
  • 34
    • 55949109674 scopus 로고    scopus 로고
    • Inhibition of p53 by pifithrin-alpha reduces myocyte apoptosis and leukocyte transmigration in aged rat hearts following 24 hours of reperfusion
    • Liu P, Xu B, Cavalieri TA, Hock CE. Inhibition of p53 by pifithrin-alpha reduces myocyte apoptosis and leukocyte transmigration in aged rat hearts following 24 hours of reperfusion. Shock 2008; 30: 545-51.
    • (2008) Shock , vol.30 , pp. 545-551
    • Liu, P.1    Xu, B.2    Cavalieri, T.A.3    Hock, C.E.4
  • 35
    • 20444417280 scopus 로고    scopus 로고
    • Apoptosis of pancreatic acinar cells in acute pancreatitis: Is it good or bad?
    • Bhatia M. Apoptosis of pancreatic acinar cells in acute pancreatitis: is it good or bad? J Cell Mol Med 2004; 8: 402-9.
    • (2004) J Cell Mol Med , vol.8 , pp. 402-409
    • Bhatia, M.1
  • 36
    • 0035719174 scopus 로고    scopus 로고
    • Effect and mechanism of somatostatin analog on apoptosis of pancreatic acinar cells in acute pancreatitis in mice
    • Yuan Y, Gong Z, Lou K, Tu S, Di Z, Xu J. Effect and mechanism of somatostatin analog on apoptosis of pancreatic acinar cells in acute pancreatitis in mice. Gastroenterol Hepatol 2001; 16: 683-88.
    • (2001) Gastroenterol Hepatol , vol.16 , pp. 683-688
    • Yuan, Y.1    Gong, Z.2    Lou, K.3    Tu, S.4    Di, Z.5    Xu, J.6
  • 37
    • 0028990714 scopus 로고
    • Detection of O2 - generation and neutrophil accumulation in rat lungs aft er acute necrotizing pancreatitis
    • Murakami H, Nakao A, Kishimoto W, Nakano M, Takagel H. Detection of O2 - generation and neutrophil accumulation in rat lungs aft er acute necrotizing pancreatitis. Surgery 1995; 118: 547-54.
    • (1995) Surgery , vol.118 , pp. 547-554
    • Murakami, H.1    Nakao, A.2    Kishimoto, W.3    Nakano, M.4    Takagel, H.5
  • 38
    • 0029093069 scopus 로고
    • Vasoactive mediators and the progression from edematous to necrotizing experimental acute pancreatitis
    • Weidenhach H, Lerch MM, Gress TM, Pfaff D, Turi S, Adler G. Vasoactive mediators and the progression from edematous to necrotizing experimental acute pancreatitis. Gut 1995; 37: 434-40.
    • (1995) Gut , vol.37 , pp. 434-440
    • Weidenhach, H.1    Lerch, M.M.2    Gress, T.M.3    Pfaff, D.4    Turi, S.5    Adler, G.6
  • 39
    • 0036183821 scopus 로고    scopus 로고
    • Role of activation peptides from pancreatic proenzymes in the diagnosis and prognosis of acute pancreatitis
    • Borgström A, Appelros S, Müller CA, Uhl W, Büchler MW. Role of activation peptides from pancreatic proenzymes in the diagnosis and prognosis of acute pancreatitis. Surgery 2002; 131: 125-28.
    • (2002) Surgery , vol.131 , pp. 125-128
    • Borgström, A.1    Appelros, S.2    Müller, C.A.3    Uhl, W.4    Büchler, M.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.