Use of a mathematical model of rodent in vitro benzene metabolism to predict human in vitro metabolism data

Carcinogenesis

Volumn 20, Issue 8, 1999, Pages 1511-1520

  Lovern, Mark R ^a,b   Maris, M Elizabeth ^a,b   Schlosser, Paul M ^a  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; BENZENE DERIVATIVE; BENZENE EPOXIDE; CARBON 14; CYTOCHROME P450 ISOENZYME; ENZYME INHIBITOR; EPOXIDE HYDROLASE; HYDROQUINONE; LIVER ENZYME; PHENOL; TRICHLOROPROPYLENE OXIDE; UNCLASSIFIED DRUG; VINYLIDENE CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; APLASTIC ANEMIA; ARTICLE; BLOOD TOXICITY; BONE MARROW TOXICITY; CANCER RISK; CONTROLLED STUDY; DRUG METABOLISM; ISOTOPE LABELING; LEUKEMIA; LIVER METABOLISM; MALE; MATHEMATICAL MODEL; MICROSOME; MOUSE; NONHUMAN; POLLUTANT; PRIORITY JOURNAL; RAT;

ANIMALS; BENZENE; CARCINOGENS; CYTOCHROME P-450 CYP2E1; ENZYME INHIBITORS; HUMANS; MALE; MICE; MICROSOMES, LIVER; MODELS, BIOLOGICAL; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, INBRED F344; TRICHLOROEPOXYPROPANE;

EID: 0032868290     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.8.1511     Document Type: Article

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