Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Ramot, Yuval ^a,b   Tiede, Stephan ^b   Bíró, Tamás ^c   Bakar, Mohd Hilmi Abu ^b,d   Sugawara, Koji ^b   Philpott, Michael P ^e   Harrison, Wesley ^e   Pietilä, Marko ^f   Paus, Ralf ^b,g  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b UNIVERSITY OF LÜBECK   (Germany)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d SCHOOL OF HEALTH SCIENCES   (Malaysia)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^f UNIVERSITY OF EASTERN FINLAND   (Finland)

^g UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 15; CYTOKERATIN 19; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA POLYPEPTIDE; ORNITHINE DECARBOXYLASE; POLYAMINE; REGULATOR PROTEIN; SOLUTE CARRIER FAMILY MEMBER 3; SPERMIDINE; SYNOVIAL APOPTOSIS INHIBITOR 1; UNCLASSIFIED DRUG; KERATIN;

ARTICLE; CELL ADHESION; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMING UNIT E; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; EPITHELIUM CELL; FEMALE; GENE; GENE TARGETING; HAIR FOLLICLE; HAIR GROWTH; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KERATINOCYTE; MITOCHONDRIAL PERMEABILITY; NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA POLYPEPTIDE GENE; ORNITHINE DECARBOXYLASE GENE; POLYAMINE SYNTHESIS; PROTEIN EXPRESSION; SOLUTE CARRIER FAMILY MEMBER 3 GENE; STEM CELL EXPANSION; SYNOVIAL APOPTOSIS INHIBITOR 1 GENE; UPREGULATION; CELL SEPARATION; CLONOGENIC ASSAY; CYTOLOGY; ENZYMOLOGY; EPIDERMIS; GENE EXPRESSION PROFILING; GENETICS; GROWTH, DEVELOPMENT AND AGING; HAIR; METABOLISM; PROMOTER REGION; STEM CELL;

CELL PROLIFERATION; CELL SEPARATION; COLONY-FORMING UNITS ASSAY; EPIDERMIS; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; HAIR; HAIR FOLLICLE; HUMANS; KERATINOCYTES; KERATINS; ORNITHINE DECARBOXYLASE; PROMOTER REGIONS, GENETIC; SPERMIDINE; STEM CELLS; UP-REGULATION;

EID: 79960822716     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022564     Document Type: Article

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