Markers of inflammation are heritable and associated with subcutaneous and ectopic skeletal muscle adiposity in african ancestry families

Metabolic Syndrome and Related Disorders

Volumn 9, Issue 4, 2011, Pages 319-326

  Miljkovic, Iva ^a   Kuipers, Allison L ^a   Kammerer, Candace M ^b   Wang, Xiaojing ^c   Bunker, Clareann H ^a   Patrick, Alan L ^a,d   Wheeler, Victor W ^a,d   Kuller, Lewis H ^a   Evans, Rhobert W ^a   Zmuda, Joseph M ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d Tobago Health Studies Office   (Trinidad and Tobago)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; INSULIN; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; AGING; ARTICLE; BODY FAT DISTRIBUTION; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; FAMILY; FEMALE; HERITABILITY; HUMAN; HYPERINSULINEMIA; INFLAMMATION; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; MYOSTEATOSIS; NEGRO; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SKELETAL MUSCLE; SUBCUTANEOUS FAT;

ADIPOSITY; ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; CHORISTOMA; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MALE; MIDDLE AGED; MUSCLE, SKELETAL; RISK FACTORS; SUBCUTANEOUS FAT; TRINIDAD AND TOBAGO; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 79960790632     PISSN: 15404196     EISSN: 15578518     Source Type: Journal    
DOI: 10.1089/met.2010.0133     Document Type: Article

References (46)

1. Brancati FL, Kao WH, Folsom AR, Watson RL, Szklo M. Incident type 2 diabetes mellitus in African American and white adults: The Atherosclerosis Risk in Communities Study. JAMA 2000;283:2253-2259. (Pubitemid 30246776)
2. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002;288:1723-1727.
3. Cowie CC, Rust KF, Byrd-Holt DD, Eberhardt MS, Flegal KM, Engelgau MM, Sayday SH, Willaims DE, Geiss LS, Gregg EW. Prevalence of diabetes and impaired fasting glucose in adults in the U.S. population. Diabetes Care 2006;29:1263-1268.
4. Haffner SM, D'Agostino R, Saad MF, Rewers M, Mykkanen L, Selby J, Howard G, Savage PJ, Hamman RF, Wagenknecht LE. Increased insulin resistance and insulin secretion in nondiabetic African-Americans and Hispanics compared with non-Hispanic whites. The Insulin Resistance Atherosclerosis Study. Diabetes 1996;45:742-748.
5. Hajjar I, Kotchen TA. Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000. JAMA 2003;290:199-206. (Pubitemid 37430058)
6. Hennis A, Wu SY, Nemesure B, Li X, Leske MC. Diabetes in a Caribbean population: Epidemiological profile and implications. Int J Epidemiol 2002;31:234-239. (Pubitemid 34284932)
7. Mbanya JCN, Motala AA, Sobngwi E, Assah FK, Enoru ST. Diabetes in sub-Saharan Africa. The Lancet 2010;375:2254-2266.
8. Boyne MS. Diabetes in the Caribbean: Trouble in paradise. Insulin 2009;4:94-105.
9. Malavazos AE, Corsi MM, Ermetici F, Coman C, Sardanelli F, Rossi A, Morricone L, Ambros B. Proinflammatory cytokines and cardiac abnormalities in uncomplicated obesity: Relationship with abdominal fat deposition. Nutr Metab Cardiovasc Dis 2007;17:294-302. (Pubitemid 46551684)
10. DeClercq V, Taylor C, Zahradka P. Adipose tissue: The link between obesity and cardiovascular disease. Cardiovasc Hematol Disord Drug Targets 2008;8:228-237.
11. Despres JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature 2006;444:881-887. (Pubitemid 46024995)
12. Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 2007;56:1010-1013. (Pubitemid 46525079)
13. Albu JB, Kovera AJ, Allen L, Wainwright M, Berk E, Raja- Khan N, Janumala I, Burkey B, Heshka S, Gallagher D. Independent association of insulin resistance with larger amounts of intermuscular adipose tissue and a greater acute insulin response to glucose in African American than in white nondiabetic women. Am J Clin Nutr 2005;82:1210-1217. (Pubitemid 43779719)
14. Miljkovic I, Cauley JA, Petit MA, Ensrud KE, Strotmeyer E, Sheu Y, Gordon CL, Goodpaster BH, Bunker CH, Patrick AL, Wheeler VW, Kuller LH, Faulkner KA, Zmuda JM for the Osteroporotic Fractures in Men (MrOS) Research Group the Tobago Health Studies Research Group. Greater adipose tissue infiltration in skeletal muscle among older men of African ancestry. J Clin Endocrinol Metab 2009;94:2735-2742.
15. Miljkovic I, Zmuda JM. Epidemiology of myosteatosis. Curr Opin Clin Nutr Metab Care 2010;13:260-264.
16. Vettor R, Milan G, Franzin C, Sanna M, De Coppi P, Rizzuto R, Federspil G. The origin of intermuscular adipose tissue and its pathophysiological implications. Am J Physiol Endocrinol Metab 2009;297:E987-E998.
17. Fox ER, Benjamin EJ, Sarpong DF, Rotimi CN, Wilson JG, Steffes MW, Chen G, Adeyemo A, Taylor JK, Samdarshi TE, Taylor HA. Epidemiology, heritability, and genetic linkage of C-reactive protein in African Americans (from the Jackson Heart Study). Am J Cardiol 2008;102:835-841.
18. Lakka TA, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Bouchard C. Quantitative trait locus on chromosome 20q13 for plasma levels of C-reactive protein in healthy whites: the HERITAGE Family Study. Physiol Genomics 2006;27: 103-107. (Pubitemid 46702024)
19. Population and Housing Census. Demographic Report. Office of the prime minister, republic of Trinidad and Tobago, office of the prime minister central statistical office, 35-41 Queen Street Port of Spain, PO Box 98, Trinidad and Tobago 1993; 11.
20. Miljkovic-Gacic I, Ferrell RE, Patrick AL, Kammerer CM, Bunker CH. Estimates of African, European and Native American ancestry in Afro-Caribbean men on the island of Tobago. Human Heredity 2005;60:129-133. (Pubitemid 43130418)
21. Reiner AP, Ziv E, Lind DL, Nievergelt CM, Schork NJ, Cummings SR, et al. Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet 2005;76:463-477. (Pubitemid 40250526)
22. Parra EJ, Marcini A, Akey J, Martinson J, Batzer MA, Cooper R, et al. Estimating African American admixture proportions by use of population-specific alleles. Am J Hum Genet 1998;63:1839-1851. (Pubitemid 30415746)
23. Parra EJ, Kittles RA, Argyropoulos G, Pfaff CL, Hiester K, Bonilla C, et al. Ancestral proportions and admixture dynamics in geographically defined African Americans living in South Carolina. Am J Phys Anthropol 2001;114:18-29. (Pubitemid 32047315)
24. Bunker CH, Patrick AL, Konety BR, Dhir R, Brufsky AM, Vivas CA, et al. High prevalence of screening-detected prostate cancer among Afro-Caribbeans: the Tobago Prostate Cancer Survey. Cancer Epidemiol Biomarkers Prev 2002;11:726-729. (Pubitemid 34851906)
25. Simonsick EM, Maffeo CE, Rogers SK, Skinner EA, Davis D, Guralnik JM, Fried LP. Methodology and feasibility of a home-based examination in disabled older women: The Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci 1997;52:M264-M274. (Pubitemid 27413627)
26. Goodpaster BH, Kelley DE, Thaete FL, He J, Ross R. Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content. J Appl Physiol 2000;89:104-110. (Pubitemid 30482569)
27. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419. (Pubitemid 15018832)
28. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, Monauni T, Muggeo M. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: Studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 2000;23:57-63. (Pubitemid 30022895)
29. Almasy L, Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998;62:1198-1211. (Pubitemid 28199022)
30. Almasy L, Dyer TD, Blangero J. Bivariate quantitative trait linkage analysis: pleiotropy versus co-incident linkages. Genet Epidemiol 1997;14:953-958. (Pubitemid 28027515)
31. Zoico E, Rossi A, Di Francesco V, Sepe A, Olioso D, Pizzini F, Fantin F, Bosello O, Cominancini L, Harris TB, Zamboni M. Adipose tissue infiltration in skeletal muscle of healthy elderly men: Relationships with body composition, insulin resistance, and inflammation at the systemic and tissue level. J Gerontol A: Biol Sci Med Sci 2010;65A:295-299.
32. Beasley LE, Koster A, Newman AB, Javaid MK, Ferrucci L, Kritchevsky SB, Kuller LH, Pahor M, Schaap LA, Visser M, Rubin SM, Goodpaster BH, Harris TB, and The Health ABC Study. Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity (Silver Spring) 2009;17:1062-1069.
33. Gan SK, Samaras K, Thompson CH, Kraegen EW, Carr A, Cooper DA, Chisholm DJ. Altered myocellular and abdominal fat partitioning predict disturbance in insulin action in HIV protease inhibitor-related lipodystrophy. Diabetes 2002; 51:3163-3169. (Pubitemid 35246961)
34. Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin- 6: Depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998;83:847-850. (Pubitemid 28496456)
35. Iwasaki T, Nakajima A, Yoneda M, Terauchi Y. Relationship between the serum concentrations of C-reactive protein and parameters of adiposity and insulin resistance in patients with type 2 diabetes mellitus. Endocr J 2006;53:345-356. (Pubitemid 43988164)
36. Bruunsgaard H, Pedersen M, Pedersen BK. Aging and proinflammatory cytokines. Curr Opin Hematol 2001;8:131-136. (Pubitemid 32324632)
37. Albert MA, Ridker PM. Inflammatory biomarkers in African Americans: A potential link to accelerated atherosclerosis. Rev Cardiovasc Med 2004;5(Suppl 3):S22-S27. (Pubitemid 39199217)
38. Khera A, McGuire DK, Murphy SA, Stanek HG, Das SR, Vongpatanasin W, Wians FH, Grundy SM, de Lemos JA. Race and gender differences in C-reactive protein levels. J Am Coll Cardiol 2005;46:464-469. (Pubitemid 41040287)
39. Kelley-Hedgepeth A, Lloyd-Jones DM, Colvin A, Matthews KA, Johnston J, Sowers MR, Sternfeld B, Pasternak RC, Chae CU, for the SWAN Investigators. Ethnic differences in C-reactive protein concentrations. Clin Chem 2008;54:1027-037. (Pubitemid 351793410)
40. Carroll JF, Fulda KG, Chiapa AL, Rodriquez M, Phelps DR, Cardarelli KM, Vishwanatha JK, Cardarelli R. Impact of race/ ethnicity on the relationship between visceral fat and inflammatory biomarkers. Obesity (Silver Spring) 2009;17:1420-1427.
41. Ix JH, Allison MA, Denenberg JO, Cushman M, Criqui MH. Novel cardiovascular risk factors do not completely explain the higher prevalence of peripheral arterial disease among African Americans. The San Diego Population Study. J Am Coll Cardiol 2008;51:2347-2354. (Pubitemid 351783358)
42. Wener MH, Daum PR, McQuillan GM. The influence of age, sex, and race on the upper reference limit of serum C-reactive protein concentration. J Rheumatol 2000;27:2351-2359.
43. An J, Ribeiro RC, Webb P, Gustafsson JA, Kushner PJ, Baxter JD, Leitman DC. Estradiol repression of tumor necrosis factor-alpha transcription requires estrogen receptor activation function-2 and is enhanced by coactivators. Proc Natl Acad Sci USA 1999;96:15161-15166. (Pubitemid 30019782)
44. Stein CM, Guwatudde D, Nakakeeto M, Peters P, Elston RC, Tiwari HK, Mugerwa R, Whalen CC. Heritability analysis of cytokines as intermediate phenotypes of tuberculosis. J Infect Dis 2003;187:1679-1685. (Pubitemid 36667877)
45. Lee SJ, Janssen I, Heymsfield SB, Ross R. Relation between whole-body and regional measures of human skeletal muscle. Am J Clin Nutr 2004;80:1215-1221. (Pubitemid 41350681)
46. Larson-Meyer DE, Smith SR, Heilbronn LK, Kelley DE, Ravussin E, Newcomer BR. Muscle-associated triglyceride measured by computed tomography and magnetic resonance spectroscopy. Obesity (Silver Spring) 2006;14:73-87. (Pubitemid 46214777)