-
1
-
-
14944354802
-
+ cells and remain stable after clonal expansion
-
DOI 10.1182/blood-2004-07-2683
-
Libura, J.; Slater, D.J.; Felix, C.A.; Richardson, C. Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34(+) cells and remain stable after clonal expansion. Blood 2005, 105, 2124-2131. (Pubitemid 40731801)
-
(2005)
Blood
, vol.105
, Issue.5
, pp. 2124-2131
-
-
Libura, J.1
Slater, D.J.2
Felix, C.A.3
Richardson, C.4
-
2
-
-
20144388623
-
DNA topoisomerase II in therapy-related acute promyelocytic leukemia
-
DOI 10.1056/NEJMoa042715
-
Mistry, A.R.; Felix, C.A.; Whitmarsh, R.J.; Mason, A.; Reiter, A.; Cassinat, B.; Parry, A.; Walz, C.; Wiemels, J.L.; Segal, M.R.; et al. DNA topoisomerase II in therapy-related acute promyelocytic leukemia. New Engl. J. Med. 2005, 352, 1529-1538. (Pubitemid 40517093)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.15
, pp. 1529-1538
-
-
Mistry, A.R.1
Felix, C.A.2
Whitmarsh, R.J.3
Mason, A.4
Reiter, A.5
Cassinat, B.6
Parry, A.7
Walz, C.8
Wiemels, J.L.9
Segal, M.R.10
Ades, L.11
Blair, I.A.12
Osheroff, N.13
Peniket, A.J.14
Lafage-Pochitaloff, M.15
Cross, N.C.P.16
Chomienne, C.17
Solomon, E.18
Fenaux, P.19
Grimwade, D.20
more..
-
3
-
-
28844479353
-
Progress in studies on naturally occurring polyacetylenes
-
Nie, B.; Lu, Y.; Chen, Z. Progress in studies on naturally occurring polyacetylenes. Chin. Tradit. Herbal Drugs 2002, 33, 1050-1053.
-
(2002)
Chin. Tradit. Herbal Drugs
, vol.33
, pp. 1050-1053
-
-
Nie, B.1
Lu, Y.2
Chen, Z.3
-
4
-
-
33646402325
-
Bioactive polyacetylenes in food plants of the Apiaceae family: Occurrence, bioactivity and analysis
-
Christensen, L.P.; Brandt, K. Bioactive polyacetylenes in food plants of the Apiaceae family: Occurrence, bioactivity and analysis. J. Pharmaceut. Biomed. Anal. 2006, 41, 683-693.
-
(2006)
J. Pharmaceut. Biomed. Anal
, vol.41
, pp. 683-693
-
-
Christensen, L.P.1
Brandt, K.2
-
5
-
-
16344370733
-
Polyacetylenes from the apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities
-
DOI 10.1021/jf048041s
-
Zidorn, C.; Johrer, K.; Ganzera, M.; Schubert, B.; Sigmund, E.M.; Mader, J.; Greil, R.; Ellmerer, E.P.; Stuppner, H. Polyacetylenes from the Apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities. J. Agr. Food Chem. 2005, 53, 2518-2523. (Pubitemid 40471733)
-
(2005)
Journal of Agricultural and Food Chemistry
, vol.53
, Issue.7
, pp. 2518-2523
-
-
Zidorn, C.1
Johrer, K.2
Ganzera, M.3
Schubert, B.4
Sigmund, E.M.5
Mader, J.6
Greil, R.7
Ellmerer, E.P.8
Stuppner, H.9
-
6
-
-
2342456592
-
Health promoting compounds in vegetables and fruits: A systematic approach for identifying plant components with impact on human health
-
DOI 10.1016/j.tifs.2003.12.003, PII S092422440400007X
-
Brandt, K.; Christensen, L.P.; Hansen-Møller, J.; Hansen, S.L.; Haraldsdottir, J.; Jespersen, L.; Purup, S.; Kharazmi, A.; Barkholt, V.; Frøkiær, H.; Kobæk-Larsen, M. Health promoting compounds in vegetables and fruits: A systematic approach for identifying plant components with impact on human health. Trends Food Sci. Technol. 2004, 15, 384-393. (Pubitemid 38583554)
-
(2004)
Trends in Food Science and Technology
, vol.15
, Issue.7-8
, pp. 384-393
-
-
Brandt, K.1
Christensen, L.P.2
Hansen-Moller, J.3
Hansen, S.L.4
Haraldsdottir, J.5
Jespersen, L.6
Purup, S.7
Kharazmi, A.8
Barkholt, V.9
Frokiaer, H.10
Kobaek-Larsen, M.11
-
7
-
-
34247860914
-
Biphasic effect of falcarinol on CaCo-2 cell proliferation, DNA damage, and apoptosis
-
Young, J.F.; Duthie, S.J.; Milne, L.; Christensen, L.P.; Duthie, G.G.; Bestwick, C.S. Biphasic effect of falcarinol on CaCo-2 cell proliferation, DNA damage, and apoptosis. J. Agr. Food Chem. 2007, 55, 618-623.
-
(2007)
J. Agr. Food Chem
, vol.55
, pp. 618-623
-
-
Young, J.F.1
Duthie, S.J.2
Milne, L.3
Christensen, L.P.4
Duthie, G.G.5
Bestwick, C.S.6
-
9
-
-
67650667438
-
Panaxydol inhibits the proliferation and induces the differentiation of human hepatocarcinoma cell line HepG2
-
Guo, L.C.; Song, L.; Wang, Z.J.; Zhao, W.J.; Mao, W.W.; Yin, M. Panaxydol inhibits the proliferation and induces the differentiation of human hepatocarcinoma cell line HepG2. Chem.-Biol. Inter. 2009, 181, 138-143.
-
(2009)
Chem.-Biol. Inter
, vol.181
, pp. 138-143
-
-
Guo, L.C.1
Song, L.2
Wang, Z.J.3
Zhao, W.J.4
Mao, W.W.5
Yin, M.6
-
10
-
-
79955750108
-
Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidasedependent generation of reactive oxygen species
-
Kim, J.Y.; Yu, S.J.; Oh, H.J.; Lee, J.Y.; Kim, Y.; Sohn, J. Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidasedependent generation of reactive oxygen species. Apoptosis 2011, 16, 347-358.
-
(2011)
Apoptosis
, vol.16
, pp. 347-358
-
-
Kim, J.Y.1
Yu, S.J.2
Oh, H.J.3
Lee, J.Y.4
Kim, Y.5
Sohn, J.6
-
11
-
-
34248575092
-
Induction of apoptosis in rat C6 glioma cells by panaxydol
-
DOI 10.1016/j.cellbi.2007.01.003, PII S1065699507000054
-
Hai, J.; Lin, Q.; Lu, Y.; Zhang, H.; Yi, J. Induction of apoptosis in rat C6 glioma cells by panaxydol. Cell Biol. Int. 2007, 31, 711-715. (Pubitemid 46765127)
-
(2007)
Cell Biology International
, vol.31
, Issue.7
, pp. 711-715
-
-
Hai, J.1
Lin, Q.2
Lu, Y.3
Zhang, H.4
Yi, J.5
-
12
-
-
34249990614
-
Effect of panaxynol on differentiation of HL60 cells line in vitro induced
-
Wang, Z.J.; Wu, Y.L.; Lin, Q.; Chen, H.Z.; Lu, Y. Effect of panaxynol on differentiation of HL60 cells line in vitro induced. Chin. Tradit. Herbal Drugs 2003, 34, 736-738.
-
(2003)
Chin. Tradit. Herbal Drugs
, vol.34
, pp. 736-738
-
-
Wang, Z.J.1
Wu, Y.L.2
Lin, Q.3
Chen, H.Z.4
Lu, Y.5
-
13
-
-
0001921653
-
Early features of apoptosis detected by four different flow cytometry assays
-
Overbeeke, R.; Steffens-Nakken, H.; Vermes, I.; Reutelingsperger, C.; Haanen, C. Early features of apoptosis detected by four different flow cytometry assays. Apoptosis 1998, 3, 115-121. (Pubitemid 128512712)
-
(1998)
Apoptosis
, vol.3
, Issue.2
, pp. 115-121
-
-
Overbeeke, R.1
Steffens-Nakken, H.2
Vermes, I.3
Reutelingsperger, C.4
Haanen, C.5
-
14
-
-
0025726216
-
A rapid andsimple method for measuring thymocyte apoptosis by propidium iodide staining and flow-cytometry
-
Nicoletti, I.; Migliorati, G.; Pagliacci, M.C.; Grignani, F.; Riccardi, C. A rapid andsimple method for measuring thymocyte apoptosis by propidium iodide staining and flow-cytometry. J. Immunol. Methods 1991, 139, 271-279.
-
(1991)
J. Immunol. Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
15
-
-
0344389027
-
Caspases: The proteases of the apoptotic pathway
-
Nunez, G.; Benedict, M.A.; Hu, Y.M.; Inohara, N. Caspases: The proteases of the apoptotic pathway. Oncogene 1998, 17, 3237-3245. (Pubitemid 29043976)
-
(1998)
Oncogene
, vol.17
, Issue.25
, pp. 3237-3245
-
-
Nunez, G.1
Benedict, M.A.2
Hu, Y.3
Inohara, N.4
-
16
-
-
0032724653
-
Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation
-
Wolf, B.B.; Schuler, M.; Echeverri, F.; Green, D.R. Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation. J. Biol. Chem. 1999, 274, 30651-30656.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 30651-30656
-
-
Wolf, B.B.1
Schuler, M.2
Echeverri, F.3
Green, D.R.4
-
17
-
-
36749025313
-
Protein kinase Cdelta and apoptosis
-
Reyland, M.E. Protein kinase Cdelta and apoptosis. Biochem. Soc. Trans. 2007, 35, 1001-1004.
-
(2007)
Biochem. Soc. Trans
, vol.35
, pp. 1001-1004
-
-
Reyland, M.E.1
-
18
-
-
33646901676
-
Suppression of apoptosis in the protein kinase Cδ null mouse in vivo
-
DOI 10.1074/jbc.M507851200
-
Humphries, M.J.; Limesand, K.H.; Schneider, J.C.; Nakayama, K.I.; Anderson, S.M.; Reyland, M.E. Suppression of apoptosis in the protein kinase Cdelta null mouse in vivo. J. Biol. Chem. 2006, 281, 9728-9737. (Pubitemid 43864691)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.14
, pp. 9728-9737
-
-
Humphries, M.J.1
Limesand, K.H.2
Schneider, J.C.3
Nakayama, K.I.4
Anderson, S.M.5
Reyland, M.E.6
-
19
-
-
72249120375
-
Caspasemediated protein kinase C-delta cleavage is necessary for apoptosis of vascular smooth muscle cells
-
Kato, K.; Yamanouchi, D.; Esbona, K.; Kamiya, K.; Zhang, F.; Kent, K.C.; Liu, B. Caspasemediated protein kinase C-delta cleavage is necessary for apoptosis of vascular smooth muscle cells. Amer. J. Physiol. Heart Circ. Phy. 2009, 297, H2253-H2261.
-
(2009)
Amer. J. Physiol. Heart Circ. Phy
, vol.297
-
-
Kato, K.1
Yamanouchi, D.2
Esbona, K.3
Kamiya, K.4
Zhang, F.5
Kent, K.C.6
Liu, B.7
-
20
-
-
15744392746
-
Protein kinase Cδ is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells
-
DOI 10.1124/jpet.104.078469
-
Latchoumycandane, C.; Anantharam, V.; Kitazawa, M.; Yang, Y.; Kanthasamy, A.; Kanthasamy, A.G. Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells. J. Pharmacol. Exp. Ther. 2005, 313, 46-55. (Pubitemid 40411326)
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.313
, Issue.1
, pp. 46-55
-
-
Latchoumycandane, C.1
Anantharam, V.2
Kitazawa, M.3
Yang, Y.4
Kanthasamy, A.5
Kanthasamy, A.G.6
-
21
-
-
69549120612
-
Etoposide induces protein kinase Cδ- and Caspase-3- Dependent apoptosis in neuroblastoma cancer cells
-
Day, T.W.; Wu, C.-H.; Safa, A.R. Etoposide Induces Protein Kinase Cδ- and Caspase-3- Dependent Apoptosis in Neuroblastoma Cancer Cells. Mol. Pharmacol. 2009, 76, 632-640.
-
(2009)
Mol. Pharmacol
, vol.76
, pp. 632-640
-
-
Day, T.W.1
Wu, C.-H.2
Safa, A.R.3
-
22
-
-
57149125318
-
Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation
-
Sun, F.; Kanthasamy, A.; Song, C.; Yang, Y.; Anantharam, V.; Kanthasamy, A.G. Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation. J. Cell. Mol. Med. 2008, 12, 2467-2481.
-
(2008)
J. Cell. Mol. Med
, vol.12
, pp. 2467-2481
-
-
Sun, F.1
Kanthasamy, A.2
Song, C.3
Yang, Y.4
Anantharam, V.5
Kanthasamy, A.G.6
-
23
-
-
20944436253
-
Nanomolar concentration of NSC606985, a camptothecin analog, induces leukemic-cell apoptosis through protein kinase Cδ-dependent mechanisms
-
DOI 10.1182/blood-2004-10-4011
-
Song, M.G.; Gao, S.M.; Du, K.M.; Xu, M.; Yu, Y.; Zhou, Y.H.; Wang, Q.; Chen, Z.; Zhu, Y.S.; Chen, G.Q. Nanomolar concentration of NSC606985, a camptothecin analog, induces leukerniccell apoptosis through protein kinase C delta-dependent mechanisms. Blood 2005, 105, 3714-3721. (Pubitemid 40628221)
-
(2005)
Blood
, vol.105
, Issue.9
, pp. 3714-3721
-
-
Song, M.-G.1
Gao, S.-M.2
Du, K.-M.3
Xu, M.4
Yu, Y.5
Zhou, Y.-H.6
Wang, Q.7
Chen, Z.8
Zhu, Y.-S.9
Chen, G.-Q.10
-
24
-
-
0033233483
-
Protein kinase Cδ targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector
-
Li, L.; Lorenzo, P.S.; Bogi, K.; Blumberg, P.M.; Yuspa, S.H. Protein kinase C delta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Mol. Cell Biol. 1999, 19, 8547-8558. (Pubitemid 30414048)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.12
, pp. 8547-8558
-
-
Li, L.1
Lorenzo, P.S.2
Bogi, K.3
Blumberg, P.M.4
Yuspa, S.H.5
-
25
-
-
20344369354
-
Study on the lipophilic components of Panax notoginseng
-
Lin, Q.; Zhao, X.; Lu, Y.; Chen, Z.N. Study on the lipophilic components of Panax notoginseng. Chin. Tradit. Herbal Drugs 2002, 33, 490-492.
-
(2002)
Chin. Tradit. Herbal Drugs
, vol.33
, pp. 490-492
-
-
Lin, Q.1
Zhao, X.2
Lu, Y.3
Chen, Z.N.4
-
26
-
-
0030835144
-
The absolute stereostructures of the polyacetylenic constituents of Ginseng Radix Rubra
-
DOI 10.1016/S0040-4020(97)10026-6, PII S0040402097100266
-
Kobayashi, M.; Mahmud, T.; Umezome, T.; Wang, W.W.; Murakami, N.; Kitagawa, I. The absolute stereostructures of the polyacetylenic constituents of Ginseng Radix Rubra. Tetrahedron 1997, 53, 15691-15700. (Pubitemid 27472958)
-
(1997)
Tetrahedron
, vol.53
, Issue.46
, pp. 15691-15700
-
-
Kobayashi, M.1
Mahmud, T.2
Umezome, T.3
Wang, W.4
Murakami, N.5
Kitagawa, I.6
-
27
-
-
0031469063
-
Polyacetylene analogs, isolated from hairy roots of panax ginseng, inhibit Acyl-CoA: Cholesterol acyltransferase
-
Kwon, B.M.; Ro, S.H.; Kim, M.K.; Nam, J.Y.; Jung, H.J.; Lee, I.R.; Kim, Y.K.; Bok, S.H. Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA: Cholesterol acyltransferase. Planta Med. 1997, 63, 552-553.
-
(1997)
Planta Med
, vol.63
, pp. 552-553
-
-
Kwon, B.M.1
Ro, S.H.2
Kim, M.K.3
Nam, J.Y.4
Jung, H.J.5
Lee, I.R.6
Kim, Y.K.7
Bok, S.H.8
-
28
-
-
0032542146
-
First total synthesis of optically active panaxydol, a potential antitumor agent isolated from Panax ginseng
-
PII S0040403998022126
-
Lu, W.; Zheng, G.G.; Aisa, H.A.; Cai, J.C. First total synthesis of optically active panaxydol, a potential antitumor agent isolated from Panax ginseng. Tetrahedron Lett. 1998, 39, 9521-9522. (Pubitemid 28541834)
-
(1998)
Tetrahedron Letters
, vol.39
, Issue.51
, pp. 9521-9522
-
-
Lu, W.1
Zheng, G.2
Haji3
Aisa, A.4
Cai, J.5
-
29
-
-
0032251817
-
Total synthesis of 3 (R)-panaxynol
-
Zheng, G.R.; Lu, W.; Aisa, H.A.; Cai, J.C. Total synthesis of 3 (R)-panaxynol. Chin. Chem. Lett. 1998, 9, 1079-1080. (Pubitemid 128536738)
-
(1998)
Chinese Chemical Letters
, vol.9
, Issue.12
, pp. 1079-1080
-
-
Zheng, G.R.1
Lu, W.2
Aisa, H.A.3
Cai, J.C.4
|