Putative proto-oncogene pir expression is significantly up-regulated in the spleen and kidney of cytosolic superoxide dismutase-deficient mice

Redox Report

Volumn 16, Issue 3, 2011, Pages 129-133

  Brzóska, Kamil ^a   Stepkowski, Tomasz M ^a   Kruszewski, Marcin ^a,b  

^a INSTITUTE OF NUCLEAR CHEMISTRY AND TECHNOLOGY   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

NF B; NRF2; Oxidative stress; Pirin; Superoxide dismutase

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; ONCOPROTEIN; PROTEIN PIR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN; CONTROLLED STUDY; CYTOSOL; ENZYME DEFICIENCY; FEMALE; GENETIC TRANSCRIPTION; GENOTYPE; HEART; IN VIVO STUDY; KIDNEY; LIVER; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; UPREGULATION; WILD TYPE;

ANIMALS; CARRIER PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; KIDNEY; LIVER; MALE; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; MODELS, ANIMAL; NF-KAPPA B P50 SUBUNIT; NFI TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SPLEEN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; UP-REGULATION;

MUS;

EID: 79960774467     PISSN: 13510002     EISSN: 17432928     Source Type: Journal    
DOI: 10.1179/1351000211Y.0000000002     Document Type: Article

References (27)

1. Wendler WM, Kremmer E, Forster R, Winnacker EL. Identification of pirin, a novel highly conserved nuclear protein. J Biol Chem 1997;272(13):8482-9.
2. Dechend R, Hirano F, Lehmann K, Heissmeyer V, Ansieau S, Wulczyn FG, et al. The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators. Oncogene 1999;18(22):3316-23.
3. Pang H, Bartlam M, Zeng Q, Miyatake H, Hisano T, Miki K, et al. Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor. J Biol Chem 2004;279(2): 1491-8.
4. Adams M, Jia Z. Structural and biochemical analysis reveal pirins to possess quercetinase activity. J Biol Chem 2005; 280(31):28675-82.
5. Gelbman BD, Heguy A, O'Connor TP, Zabner J, Crystal RG. Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis. Respir Res 2007;8:10.
6. Orzaez D, de Jong AJ, Woltering EJ. A tomato homologue of the human protein PIRIN is induced during programmed cell death. Plant Mol Biol 2001;46(4):459-68.
7. Hihara Y, Muramatsu M, Nakamura K, Sonoike K. A cyanobacterial gene encoding an ortholog of Pirin is induced under stress conditions. FEBS Lett 2004;574(1-3):101-5.
8. Licciulli S, Cambiaghi V, Scafetta G, Gruszka AM, Alcalay M. Pirin downregulation is a feature of AML and leads to impairment of terminal myeloid differentiation. Leukemia 2010;24(2): 429-37.
9. Licciulli S, Luise C, Zanardi A, Giorgetti L, Viale G, Lanfrancone L, et al. Pirin delocalization in melanoma progression identified by high content immuno-detection based approaches. BMC Cell Biol 2010;11:5.
10. Miyazaki I, Simizu S, Okumura H, Takagi S, Osada H. A smallmolecule inhibitor shows that pirin regulates migration of melanoma cells. Nat Chem Biol 2010;6(9):667-73.
11. Yoshikawa R, Yanagi H, Hashimoto-Tamaoki T, Morinaga T, Nakano Y, Noda M, et al. Gene expression in response to anti-tumour intervention by polysaccharide-K (PSK) in colorectal carcinoma cells. Oncol Rep 2004;12(6):1287-93.
12. Hubner RH, Schwartz JD, De BP, Ferris B, Omberg L, Mezey JG, et al. Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking. Mol Med 2009;15(7-8):203-19.
13. Spira A, Beane J, Shah V, Liu G, Schembri F, Yang X, et al. Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci USA 2004;101(27):10143-8.
14. Zhang Q, Pi J, Woods CG, Andersen ME. A systems biology perspective on Nrf2-mediated antioxidant response. Toxicol Appl Pharmacol 2010;244(1):84-97.
15. Perry JJ, Shin DS, Getzoff ED, Tainer JA. The structural biochemistry of the superoxide dismutases. Biochim Biophys Acta 2010;1804(2):245-62.
16. Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson RL, Van RH, et al. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 2005;24(3):367-80.
17. Ho YS, Gargano M, Cao J, Bronson RT, Heimler I, Hutz RJ. Reduced fertility in female mice lacking copper-zinc superoxide dismutase. J Biol Chem 1998;273(13):7765-9.
18. Kessova IG, Ho YS, Thung S, Cederbaum AI. Alcohol-induced liver injury in mice lacking Cu, Zn-superoxide dismutase. Hepatology 2003;38(5):1136-45.
19. Busuttil RA, Garcia AM, Cabrera C, Rodriguez A, Suh Y, Kim WH, et al. Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice. Cancer Res 2005;65(24):11271-5.
20. Siomek A, Brzoska K, Sochanowicz B, Gackowski D, Rozalski R, Foksinski M, et al. Cu,Zn-superoxide dismutase deficiency in mice leads to organ-specific increase in oxidatively damaged DNA and NF-kappaB1 protein activity. Acta Biochim Pol 2010;57(4):577-83.
21. Hall TA. BioEdit: a user-friendly biological sequence alignment editor and analysis program forWindows 95/98/NT. Nucl Acids Symp Ser 1999;41:95-8.
22. Matzuk MM, Dionne L, Guo Q, Kumar TR, Lebovitz RM. Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinology 1998;139(9):4008-11.
23. Pfaffl MW, Horgan GW, Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 2002;30(9):e36.
24. Leeb M, Wutz A. Mechanistic concepts in X inactivation underlying dosage compensation in mammals. Heredity 2010;105(1): 64-70.
25. Bergman AC, Alaiya AA, Wendler W, Binetruy B, Shoshan M, Sakaguchi K, et al. Protein kinase-dependent overexpression of the nuclear protein pirin in c-JUN and RAS transformed fibroblasts. Cell Mol Life Sci 1999;55(3):467-71.
26. Brzóska K, Sochanowicz B, Siomek A, Oliński R, Kruszewski M. Alterations in the expression of genes related to NF-?B signaling in liver and kidney of CuZnSOD-deficient mice. Mol Cell Biochem 2011;353(1-2):151-7.
27. Morgan MJ, Liu ZG. Crosstalk of reactive oxygen species and NF-kappaB signaling. Cell Res 2011;21(1):103-15.