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Volumn 28, Issue 4, 2011, Pages 549-556

Expression, purification, refolding, and characterization of octreotide-interleukin-2: A chimeric tumor-targeting protein

Author keywords

Bioactivity; Expression; Interleukin 2; Octreotide; Purification; Refolding; Somatostatin receptor; Tumor target

Indexed keywords

HYBRID PROTEIN; SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR TARGETED INTERLEUKIN 2; UNCLASSIFIED DRUG;

EID: 79960760647     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.723     Document Type: Article
Times cited : (5)

References (31)
  • 1
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • DOI 10.1126/science.279.5349.377
    • Arap W, Pasqualini R and Ruoslahti E: Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279: 377-380, 1998. (Pubitemid 28063372)
    • (1998) Science , vol.279 , Issue.5349 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 4
    • 33646352962 scopus 로고    scopus 로고
    • Potent antibody therapeutics by design
    • Carter PJ: Potent antibody therapeutics by design. Nat Rev Immunol 6: 343-357, 2006.
    • (2006) Nat Rev Immunol , vol.6 , pp. 343-357
    • Carter, P.J.1
  • 5
    • 0033764170 scopus 로고    scopus 로고
    • Enhancement of tumor necrosis factor alpha Anti-tumor immunotherapeutic properties by targeted delivery aminopeptidase N(CD13)
    • Curnis F, Sacchi A, Borgna L, et al: Enhancement of tumor necrosis factor alpha Anti-tumor immunotherapeutic properties by targeted delivery aminopeptidase N(CD13). Nat Biotechnol 18: 1185-1190, 2000.
    • (2000) Nat Biotechnol , vol.18 , pp. 1185-1190
    • Curnis, F.1    Sacchi, A.2    Borgna, L.3
  • 6
    • 63849274108 scopus 로고    scopus 로고
    • Complete eradicationof human B-cell lymphoma xenografts using rituximab in combination with the immunocytokine L19-IL2
    • Schliemann C, Palumbo A, Zuberbuhler K, et al: Complete eradicationof human B-cell lymphoma xenografts using rituximab in combination with the immunocytokine L19-IL2. Blood 113: 2275-2283, 2009.
    • (2009) Blood , vol.113 , pp. 2275-2283
    • Schliemann, C.1    Palumbo, A.2    Zuberbuhler, K.3
  • 7
    • 0036194917 scopus 로고    scopus 로고
    • Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature
    • DOI 10.1038/nbt0302-264
    • Halin C, Rondini S, Nilsson F, et al: Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature. Nat Biotechnol 20: 264-269, 2002. (Pubitemid 34205419)
    • (2002) Nature Biotechnology , vol.20 , Issue.3 , pp. 264-269
    • Halin, C.1    Rondini, S.2    Nilsson, F.3    Berndt, A.4    Kosmehl, H.5    Zardi, L.6    Neri, D.7
  • 9
    • 0037731516 scopus 로고    scopus 로고
    • Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to Tumor Necrosis Factor alpha
    • Halin C, Gafner V, Villani ME, et al: Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to tumor necrosis factor alpha. Cancer Res 63: 3202-3210, 2003. (Pubitemid 36735873)
    • (2003) Cancer Research , vol.63 , Issue.12 , pp. 3202-3210
    • Halin, C.1    Gafner, V.2    Villani, M.E.3    Borsi, L.4    Berndt, A.5    Kosmehl, H.6    Zardi, L.7    Neri, D.8
  • 10
    • 20944431599 scopus 로고    scopus 로고
    • Pharmacokinetics and in vitro and in vivo anti-tumor response of an interleukin-2-human serum albumin fusion protein in mice
    • Melder RJ, Osborn BL, Riccobene T, et al: Pharmacokinetics and in vitro and in vivo anti-tumor response of an interleukin-2-human serum albumin fusion protein in mice. Cancer Immunol Immunother 54: 535-547, 2005.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 535-547
    • Melder, R.J.1    Osborn, B.L.2    Riccobene, T.3
  • 11
    • 0022387502 scopus 로고
    • In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2
    • Lotze MT, Matory YL, Ettinghausen SE, et al: In vivo administrationof purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2. J Immunol 135: 2865-2875, 1985. (Pubitemid 16217166)
    • (1985) Journal of Immunology , vol.135 , Issue.4 , pp. 2865-2875
    • Lotze, M.T.1    Matory, Y.L.2    Ettinghausen, S.E.3
  • 13
    • 0029117871 scopus 로고
    • The use of polyethyleneglycol-modified interleukin-2 (PEG-IL-2) in the treatment of patients with metastatic renal cell carcinoma and melanoma. A phase I study and a randomized prospective study comparing IL-2 alone versus IL-2 combined with PEG-IL-2
    • Yang JC, Topalian SL, Schwartzentruber DJ, et al: The use of polyethyleneglycol-modified interleukin-2 (PEG-IL-2) in the treatment of patients with metastatic renal cell carcinoma and melanoma. A phase I study and a randomized prospective study comparing IL-2 alone versus IL-2 combined with PEG-IL-2. Cancer 76: 687-694, 1995.
    • (1995) Cancer , vol.76 , pp. 687-694
    • Yang, J.C.1    Topalian, S.L.2    Schwartzentruber, D.J.3
  • 14
    • 58149189408 scopus 로고    scopus 로고
    • Antibody-mediated delivery of interleukin-2 to the stroma of breast cancer strongly enhances the potency of chemotherapy
    • Marlind J, Kaspar M, Trachsel E, et al: Antibody-mediated delivery of interleukin-2 to the stroma of breast cancer strongly enhances the potency of chemotherapy. Clin Cancer Res 14: 6515-6524, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 6515-6524
    • Marlind, J.1    Kaspar, M.2    Trachsel, E.3
  • 16
    • 67650723700 scopus 로고    scopus 로고
    • Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells
    • Kerros C, Cavey T, Sola B, Jauzac P and Allouche S: Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells. J Exp Clin Cancer Res 28: 77, 2009.
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 77
    • Kerros, C.1    Cavey, T.2    Sola, B.3    Jauzac, P.4    Allouche, S.5
  • 18
    • 27744570118 scopus 로고    scopus 로고
    • Systemic distribution of somatostatin receptor subtypes in human: An immunohistochemical study
    • DOI 10.1507/endocrj.52.605
    • Taniyama Y, Suzuki T, Mikami Y, Moriya T, Satomi S and Sasano H: Systemic distribution of somatostatin receptor subtypes in human: an immunohistochemical study. Endocr J 52: 605-611, 2005. (Pubitemid 41609051)
    • (2005) Endocrine Journal , vol.52 , Issue.5 , pp. 605-611
    • Taniyama, Y.1    Suzuki, T.2    Mikami, Y.3    Moriya, T.4    Satomi, S.5    Sasano, H.6
  • 19
    • 43749121851 scopus 로고    scopus 로고
    • Function and expression of somatostatin receptors of the endocrine pancreas
    • Strowski MZ and Blake AD: Function and expression of somatostatin receptors of the endocrine pancreas. Mol Cell Endocrinol 286: 169-179, 2008.
    • (2008) Mol Cell Endocrinol , vol.286 , pp. 169-179
    • Strowski, M.Z.1    Blake, A.D.2
  • 20
    • 0028909323 scopus 로고
    • Multiple actions of somatostatin in neoplastic disease
    • Reubi JC and Laissue JA: Multiple actions of somatostatin in neoplastic disease. Trends Pharmacol Sci 16: 110-115, 1995.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 110-115
    • Reubi, J.C.1    Laissue, J.A.2
  • 21
    • 0034924612 scopus 로고    scopus 로고
    • Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands
    • DOI 10.1007/s002590100541
    • Reubi JC, Waser B, Schaer JC and Laissue JA: Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands. Eur J Nucl Med 28: 836-846, 2001. (Pubitemid 32662546)
    • (2001) European Journal of Nuclear Medicine , vol.28 , Issue.7 , pp. 836-846
    • Reubi, J.C.1    Waser, B.2    Schaer, J.-C.3    Laissue, J.A.4
  • 22
    • 0037233574 scopus 로고    scopus 로고
    • Expression of somatostatin receptor subtypes 1 to 5 in tumor tissue and intratumoral vessels in malignant endocrine pancreatic tumors
    • DOI 10.1385/MO:20:1:59
    • Fjallskog ML, Ludvigsen E, Stridsberg M, Oberg K, Eriksson B and Janson ET: Expression of somatostatin receptor subtypes 1 to 5 in tumor tissue and intratumoral vessels in malignant endocrine pancreatic tumors. Med Oncol 20: 59-67, 2003. (Pubitemid 36344027)
    • (2003) Medical Oncology , vol.20 , Issue.1 , pp. 59-67
    • Fjallskog, M.-L.1    Ludvigsen, E.2    Stridsberg, M.3    Oberg, K.4    Eriksson, B.5    Janson, E.T.6
  • 23
    • 0346458489 scopus 로고    scopus 로고
    • Somatostatin receptors in gastroentero-pancreatic neuroendocrine tumours
    • DOI 10.1677/erc.0.0100451
    • de Herder WW, Hofland LJ, van der Lely AJ and Lamberts SW: Somatostatin receptors in gastroentero-pancreatic neuroendocrine tumours. Endocr Relat Cancer 10: 451-458, 2003. (Pubitemid 38094881)
    • (2003) Endocrine-Related Cancer , vol.10 , Issue.4 , pp. 451-458
    • De Herder, W.W.1    Hofland, L.J.2    Van Der, L.A.J.3    Lamberts, S.W.J.4
  • 24
    • 21644450897 scopus 로고    scopus 로고
    • Somatostatin receptors in primary human breast cancer: Quantitative analysis of mRNA for subtypes 1-5 and correlation with receptor protein expression and tumor pathology
    • DOI 10.1007/s10549-005-2414-0
    • Kumar U, Grigorakis SI, Watt HL, et al: Somatostatin receptors in primary human breast cancer: quantitative analysis of mRNA for subtypes 1-5 and correlation with receptor protein expression and tumor pathology. Breast Cancer Res Treat 92: 175-186, 2005. (Pubitemid 40933583)
    • (2005) Breast Cancer Research and Treatment , vol.92 , Issue.2 , pp. 175-186
    • Kumar, U.1    Grigorakis, S.I.2    Watt, H.L.3    Sasi, R.4    Snell, L.5    Watson, P.6    Chaudhari, S.7
  • 25
    • 0035078132 scopus 로고    scopus 로고
    • Somatostatin analogs for cancer treatment and diagnosis: An overview
    • Scarpignato C and Pelosini I: Somatostatin analogs for cancer treatment and diagnosis: an overview. Chemotherapy 47 (Suppl 2): S1-S29, 2001.
    • (2001) Chemotherapy , vol.47 , Issue.SUPPL. 2
    • Scarpignato, C.1    Pelosini, I.2
  • 26
    • 78650884323 scopus 로고    scopus 로고
    • Somatostatin receptor-targeted anti-cancer therapy
    • Sun LC and Coy DH: Somatostatin receptor-targeted anti-cancer therapy. Curr Drug Deliv 8: 2-10, 2011.
    • (2011) Curr Drug Deliv , vol.8 , pp. 2-10
    • Sun, L.C.1    Coy, D.H.2
  • 29
    • 79960756738 scopus 로고    scopus 로고
    • Measurement of interleukin-2 by bioassay
    • O'Neill LAJ and Bowie A (eds). Humana Press Inc., Totowa
    • Weston L: Measurement of interleukin-2 by bioassay. In: Interleukin Protocols. O'Neill LAJ and Bowie A (eds). Humana Press Inc., Totowa, pp186-192, 2001.
    • (2001) Interleukin Protocols , pp. 186-192
    • Weston, L.1
  • 31
    • 0000893108 scopus 로고
    • Studies on the reduction and re-formation of protein disulfide bonds
    • Anfinsen CB and Haber E: Studies on the reduction and re-formation of protein disulfide bonds. J Biol Chem 236: 1361-1363, 1961.
    • (1961) J Biol Chem , vol.236 , pp. 1361-1363
    • Anfinsen, C.B.1    Haber, E.2


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