Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus

European Journal of Immunology

Volumn 41, Issue 8, 2011, Pages 2207-2216

  Billiard, Fabienne ^a   Kirshner, Jessica R ^a   Tait, Michelle ^a   Danave, Amanda ^a   Taheri, Sean ^a   Zhang, Wen ^a   Waite, Janelle C ^a   Olson, Kara ^a   Chen, Guoying ^a   Coetzee, Sandra ^a   Hylton, Donna ^a   Murphy, Andrew J ^a   Yancopoulos, George D ^a   Thurston, Gavin ^a   Skokos, Dimitris ^a  

^a REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

Notch Dll4 signaling; T cell development; Thymic involution

Indexed keywords

DELTA LIKE LIGAND 4; DELTA LIKE LIGAND 4 ANTIBODY; HERMES ANTIGEN; MEMBRANE PROTEIN; NOTCH RECEPTOR; PROTEIN ANTIBODY; STEM CELL FACTOR; UNCLASSIFIED DRUG; VELOCIMMUNE;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CD25+ T LYMPHOCYTE; CD4 CD8 RATIO; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL MATURATION; CONTROLLED STUDY; FEMALE; HOMEOSTASIS; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE; THYMUS;

AGE FACTORS; ANIMALS; ANTIBODIES; ATROPHY; B-LYMPHOCYTES; CELL DIFFERENTIATION; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HOMEOSTASIS; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; THYMUS GLAND; TIME FACTORS;

EID: 79960723074     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201041343     Document Type: Article

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