The effect of injection volume on disc degeneration in a rat tail model

Spine

Volumn 36, Issue 16, 2011, Pages

  Mao, Hua Jie ^a   Chen, Qi Xin ^a   Han, Bin ^a   Li, Fang Cai ^a   Feng, Jie ^a   Shi, Zhong Li ^a   Lin, Min ^a   Wang, Jun ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

disc degeneration; injection dose volume; rat tail model

Indexed keywords

GLYCOSAMINOGLYCAN POLYSULFATE; HYDROXYPROLINE; PHOSPHATE BUFFERED SALINE; PROTEOGLYCAN; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CARTILAGE CELL; COCCYGEAL BONE; CONTROLLED STUDY; DRUG INJECTION VOLUME; HISTOPATHOLOGY; IMAGE ANALYSIS; INTERVERTEBRAL DISK DEGENERATION; MALE; MORPHOLOGY; NERVE ENDING; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIOGRAPHY; RAT; TAIL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOSAMINOGLYCANS; HYDROXYPROLINE; INJECTIONS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MALE; NEEDLES; PHOSPHATES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE; TIME FACTORS; WATER;

EID: 79960700508     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3182027d42     Document Type: Article

References (38)

1. Luoma K, Riihimaki H, Luukkonen R, et al. Low back pain in relation to lumbar disc degeneration . Spine 2000;25: 487-92. (Pubitemid 30115569)
2. Carragee EJ, Don AS, Hurwitz EL, et al. 2009 ISSLS Prize Winner: Does discography cause accelerated progression of degeneration changes in the lumbar disc: a ten-year matched cohort study . Spine 2009;34: 2338-45.
3. Nishida K, Kang JD, Suh JK, et al. Adenovirus-mediated gene transfer to nucleus pulposus cells. Implications for the treatment of intervertebral disc degeneration . Spine 1998;23: 2437-42.
4. Masuda K, Oegema TR Jr, An HS . Growth factors and treatment of intervertebral disc degeneration . Spine 2004;29: 2757-69. (Pubitemid 40353262)
5. An HS, Takegami K, Kamada H, et al. Intradiscal administration of osteogenic protein-1 increases intervertebral disc height and proteoglycan content in the nucleus pulposus in normal adolescent rabbits . Spine 2005;30: 25-31. (Pubitemid 40209272)
6. Sakai D, Mochida J, Iwashina T, et al. Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration . Spine 2005;30: 2379-87. (Pubitemid 41567599)
7. Li RH, Bouxsein ML, Blake CA, et al. rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model . J Orthop Res 2003;21: 997-1004. (Pubitemid 37322380)
8. Matsuo T, Sugita T, Kubo T, et al. Injectable magnetic liposomes as a novel carrier of recombinant human BMP-2 for bone formation in a rat bone-defect model . J Biomed Mater Res A 2003;66: 747-54. (Pubitemid 37521398)
9. Han B, Zhu K, Li FC, et al. A simple disc degeneration model induced by percutaneous needle puncture in the rat tail . Spine 2008;33: 1925-34.
10. Elliott DM, Yerramalli CS, Beckstein JC, et al. The effect of relative needle diameter in puncture and sham injection animal models of degeneration . Spine 2008;33: 588-96. (Pubitemid 351451719)
11. O'Connell GD, Vresilovic EJ, Elliott DM . Comparison of animals used in disc research to human lumbar disc geometry . Spine 2007;32: 328-33. (Pubitemid 46197472)
12. Hughes PC, Tanner JM . The assessment of skeletal maturity in the growing rat . J Anat 1970;106: 371-402.
13. Norcross JP, Lester GE, Weinhold P, et al. An in vivo model of degenerative disc disease . J Orthop Res 2003;21: 183-8. (Pubitemid 36157636)
14. Masuda K, Aota Y, Muehleman C, et al. A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration . Spine 2005;30: 5-14. (Pubitemid 40209270)
15. Bland JM, Altman DG . Measurement error . BMJ 1996;313: 744.
16. Lipson SJ, Muir H . Experimental intervertebral disc degeneration: morphologic and proteoglycan changes over time . Arthritis Rheum 1981;24: 12-21. (Pubitemid 11163035)
17. Hunter CJ, Matyas JR, Duncan NA . Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison . J Anat 2004;205: 357-62. (Pubitemid 39642429)
18. Thompson JP, Pearce RH, Schechter MT, et al. Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc . Spine 1990;15: 411-5. (Pubitemid 20188043)
19. Urban JP, McMullin JF . Swelling pressure of the lumbar intervertebral discs: infl uence of age, spinal level, composition, and degeneration . Spine 1988;13: 179-87.
20. Johannessen W, Elliott DM . Effects of degeneration on the biphasic material properties of human nucleus pulposus in confi ned compression . Spine 2005;30: E724-9.
21. Buckwalter JA. Aging and degeneration of the human intervertebral disc . Spine 1995;20: 1307-14.
22. Schechtman H, Robertson PA, Broom ND . Failure strength of the bovine caudal disc under internal hydrostatic pressure . J Biomech 2006;39: 1401-9.
23. Lotz JC, Colliou OK, Chin JR, et al. Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and fi niteelement study . Spine 1998;23: 2493-506. (Pubitemid 29003523)
24. MacLean JJ, Lee CR, Alini M, et al. Anabolic and catabolic mRNA levels of the intervertebral disc vary with the magnitude and frequency of in vivo dynamic compression . J Orthop Res 2004;22: 1193-200. (Pubitemid 39317907)
25. Chen J, Yan W, Setton LA . Static compression induces zonal-specifi c changes in gene expression for extracellular matrix and cytoskeletal proteins in intervertebral disc cells in vitro . Matrix Biol 2004;22: 573-83. (Pubitemid 38283781)
26. Lotz JC, Chin JR . Intervertebral disc cell death is dependent on the magnitude and duration of spinal loading . Spine 2000;25: 1477-82.
27. Handa T, Ishihara H, Ohshima H, et al. Effects of hydrostatic pressure on matrix synthesis and matrix metalloproteinase production in the human lumbar intervertebral disc . Spine 1997;22: 1085-91. (Pubitemid 27209349)
28. Hutton WC, Elmer WA, Boden SD, et al. The effect of hydrostatic pressure on intervertebral disc metabolism . Spine 1999;24: 1507-15. (Pubitemid 29379851)
29. Hutton WC, Elmer WA, Bryce LM, et al. Do the intervertebral disc cells respond to different levels of hydrostatic pressure? Clin Biomech (Bristol, Avon) 2001;16: 728-34. (Pubitemid 33034998)
30. Chen J, Baer AE, Paik PY, et al. Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity . Biochem Biophys Res Commun 2002;293: 932-8. (Pubitemid 34694130)
31. Adams MA, Freeman BJ, Morrison HP, et al. Mechanical initiation of intervertebral disc degeneration . Spine 2000;25: 1625-36. (Pubitemid 30460463)
32. Cinotti G, Della Rocca C, Romeo S, et al. Degenerative changes of porcine intervertebral disc induced by vertebral endplate injuries . Spine 2005;30: 174-80. (Pubitemid 40348205)
33. Holm S, Holm AK, Ekstrom L, et al. Experimental disc degeneration due to endplate injury . J Spinal Disord Tech 2004;17: 64-71.
34. Rajasekaran S, Babu JN, Arun R, et al. ISSLS prize winner: A study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the infl uence of the endplate on diffusion in normal and degenerate discs . Spine 2004;29: 2654-67. (Pubitemid 40353251)
35. Roberts S, Menage J, Eisenstein SM . The cartilage end-plate and intervertebral disc in scoliosis: calcifi cation and other sequelae . J Orthop Res 1993;11: 747-57. (Pubitemid 23320924)
36. Roberts S, Urban JP, Evans H, et al. Transport properties of the human cartilage endplate in relation to its composition and calcifi cation . Spine 1996;21: 415-20. (Pubitemid 26067848)
37. Stokes IA, Iatridis JC . Mechanical conditions that accelerate intervertebral disc degeneration: overload versus immobilization . Spine 2004;29: 2724-32. (Pubitemid 40353258)
38. Butler WF. Comparative anatomy and development of the mammalian disc . In: Ghosh P, ed. The Biology of the Intervertebral Disc . Boca Raton, FL: CRC Press;1989: 84-108.