Chiral counter-current chromatography of gemifloxacin guided by capillary electrophoresis using (+)-(18-crown-6)-tetracarboxylic acid as a chiral selector

Journal of Chromatography A

Volumn 1045, Issue 1-2, 2004, Pages 119-124

  Kim, Eunsook ^a   Koo, Yoon Mo ^b   Chung, Doo Soo ^a  

^a Seoul National University   (South Korea)

^b Inha University   (South Korea)

Author keywords

Antibiotics; Counter current chromatography; Crown ethers; Enantiomer separation; Fluoroquinolones; Gemifloxacin

Indexed keywords

CARBOXYLIC ACIDS; ELECTROPHORESIS; HYDROPHOBICITY; PH EFFECTS; STEREOCHEMISTRY;

CAPILLARY ELECTROPHORESIS (CE); CHIRAL COUNTER CURRENT CHROMATOGRAPHY;

CHROMATOGRAPHIC ANALYSIS;

(18 CROWN 6)TETRACARBOXYLIC ACID; 1 BUTANOL ETHYLACETATE BIS(2 HYDROXYETHYL)AMINOTRIS(HYDROXYMETHYL)METHANE ACETATE; ACETIC ACID DERIVATIVE; BUFFER; CARBOXYLIC ACID DERIVATIVE; GEMIFLOXACIN; SOLVENT; UNCLASSIFIED DRUG; 18 CROWN 6 2,3,11,12 TETRACARBOXYLIC ACID; 18-CROWN-6 2,3,11,12-TETRACARBOXYLIC ACID; CROWN ETHER; NAPHTHYRIDINE DERIVATIVE; QUINOLONE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CAPILLARY ELECTROPHORESIS; CHIRAL CHROMATOGRAPHY; CHIRAL COUNTER CURRENT CHROMATOGRAPHY; CHIRALITY; CONCENTRATION (PARAMETERS); DRUG BINDING; ENANTIOMER; HYDROPHOBICITY; PH; PRIORITY JOURNAL; SEPARATION TECHNIQUE; CHEMISTRY; COUNTER CURRENT CHROMATOGRAPHY; METHODOLOGY;

BUFFERS; COUNTERCURRENT DISTRIBUTION; CROWN ETHERS; ELECTROPHORESIS, CAPILLARY; FLUOROQUINOLONES; HYDROGEN-ION CONCENTRATION; NAPHTHYRIDINES;

EID: 3843105593     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2004.06.006     Document Type: Article

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