The cyclohexane tolerance and Phe-Arg-β-naphtylamide susceptibility of multidrug-resistant Enterobacter cloacae clinical isolates, and the predominance of one PFGE clone in Hungary

Clinical Microbiology and Infection

Volumn 17, Issue 8, 2011, Pages 1254-1261

  Glatz, K ^a   Toth A ^a   Paszti J ^a  

^a NATIONAL CENTER FOR EPIDEMIOLOGY   (Hungary)

Author keywords

Cyclohexane tolerance; Enterobacter cloacae; ESBL; Molecular epidemiology; Multidrug resistance

Indexed keywords

AMIDE; CIPROFLOXACIN; CYCLOHEXANE; PHENYLALANYLARGINYL BETA NAPHTYLAMIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; BACTERIUM ISOLATION; BLOODSTREAM INFECTION; CLINICAL ARTICLE; CONTROLLED STUDY; DISK DIFFUSION; ENTEROBACTER CLOACAE; HEALTH CARE FACILITY; HUMAN; HUNGARY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; URINARY TRACT INFECTION; WOUND INFECTION;

ENTEROBACTER CLOACAE;

EID: 79960687552     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2010.03408.x     Document Type: Article

References (27)

1. Ramos JL, Duque E, Gallegos MT et al. Mechanisms of solvent tolerance in Gram-negative bacteria. Annu Rev Microbiol 2002; 56: 743-768.
2. Linde HJ, Notka F, Irtenkauf C et al. Increase in MICs of ciprofloxacin in vivo in two closely related clinical isolates of Enterobacter cloacae. J Antimicrob Chemother 2002; 49: 625-630.
3. Pitout JD, Reisbig MD, Venter EC et al. Modification of the double-disk test for detection of Enterobacteriaceae producing extended spectrum and AmpC β-lactamases. J Clin Microbiol 2003; 41: 3933-3935.
4. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: Seventeenth Informational Supplement M100-S17. Wayne, PA, USA: CLSI, 2007.
5. Versalovic J, Koeuth T, Lupski JR. Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes. Nucleic Acids Res 1991; 19: 6823-6831.
6. De Gheldre Y, Maes N, Rost F et al. Molecular epidemiology of an outbreak of multidrug-resistant Enterobacter aerogenes infections and in vivo emergence of imipenem resistance. J Clin Microbiol 1997; 35: 152-160.
7. Tóth A, Gacs M, Márialigeti K, Cech G, Füzi M. Occurrence and regional distribution of SHV-type extended-spectrum beta-lacatamases in Hungary. Eur J Clin Microbiol Infect Dis 2005; 24: 284-287.
8. Damjanova I, Tóth A, Pászti J, Bauerfeind A, Füzi M. Nationwide spread of clonally related CTX-M-15-producing multidrug-resistant Klebsiella pneumoniae strains in Hungary. Eur J Clin Microbiol Infect Dis 2006; 25: 275-278.
9. Glatz K, Tóth A, Pászti J. Emergence of SHV-2a producing Enterobacter cloacae in Hungary. Acta Microbiol Immunol Hung 2007; 54: 151-158.
10. Gautom RK. Rapid pulsed-field gel electrophoresis protocol for typing of Escherichia coli O157:H7 and other gram-negative organisms in 1day. J Clin Microbiol 1997; 35: 2977-2980.
11. Haertl R, Bandlow G. Epidemiological fingerprinting of Enterobacter cloacae by small-fragment restriction endonuclease analysis and pulsed-field gel electrophoresis of genomic restriction fragments. J Clin Microbiol 1993; 31: 128-133.
12. Edberg SC, Patterson JE, Smith DB. Differentiation of distribution systems, source water, and clinical coliforms by DNA analysis. J Clin Microbiol 1994; 32: 139-142.
13. Power EG. RAPD typing in microbiology. A technical review. J Hosp Infect 1996; 34: 247-265.
14. Struelens MJ, De Ryck R, Deplano A. Analysis of microbial genomic macrorestriction patterns by pulsed-field gel electrophoresis (PFGE) typing. In: Dijkshoorn L, Towner KJ, Struelens MJ, eds. New approaches for the generation and analysis of microbial typing dat. Amsterdam: Elsevier Science, 2001; 159-176.
15. White DG, Goldman JD, Demple B, Levy SB. Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli. J Bacteriol 1997; 179: 6122-6126.
16. Lomovskaya O, Warren MS, Lee A et al. Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Chemother 2001; 45: 105-116.
17. Kriengkauykiat J, Porter E, Lomovskaya O, Wong-Beringer A. Use of an efflux pump inhibitor to determine the prevalence of efflux pump-mediated fluoroquinolone resistance and multidrug resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 2005; 49: 565-570.
18. Schumacher A, Steinke P, Bohnert JA, Akova M, Jonas D, Kern WV. Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli. J Antimicrob Chemother 2006; 57: 344-348.
19. Piddock LJ. Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin Microbiol Rev 2006; 19: 382-402.
20. van Belkum A, Scherer S, van Alphen L, Verbrugh H. Short-sequence DNA repeats in prokaryotic genomes. Microbiol Mol Biol Rev 1998; 62: 275-293.
21. Deguchi T, Yasuda M, Nakano M et al. Detection of mutations in the gyrA and parC genes in quinolone-resistant clinical isolates of Enterobacter cloacae. J Antimicrob Chemother 1997; 40: 543-549.
22. Pérez A, Canle D, Latasa C et al. Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. Antimicrob Agents Chemother 2007; 51: 3247-3253.
23. Zheng J, Cui S, Meng J. Effect of transcriptional activators RamA and SoxS on expression of multidrug efflux pumps AcrAB and AcrEF in fluoroquinolone-resistant Salmonella Typhimurium. J Antimicrob Chemother 2009; 63: 95-102.
24. Ricci V, Piddock LJ. Ciprofloxacin selects for multidrug resistance in Salmonella enterica serovar Typhimurium mediated by at least two different pathways. J Antimicrob Chemother 2009; 63: 909-916.
25. Keeney D, Ruzin A, Bradford PA. RamA, a transcriptional regulator, and AcrAB, an RND-type efflux pump, are associated with decreased susceptibility to tigecycline in Enterobacter cloacae. Microb Drug Resist 2007; 13: 1-6.
26. Randall LP, Cooles SW, Sayers AR et al. Association between cyclohexane resistance in Salmonella of different serovars and increased resistance to multiple antibiotics, disinfectants and dyes. J Med Microbiol 2001; 50: 919-924.
27. Randall LP, Cooles SW, Piddock LJ, Woodward MJ. Effect of triclosan or a phenolic farm disinfectant on the selection of antibiotic-resistant Salmonella enterica. J Antimicrob Chemother 2004; 54: 621-627.