Delineation of the Molecular Mechanisms of Nucleoside Recognition by Cytidine Deaminase through Virtual Screening

ChemMedChem

Volumn 6, Issue 8, 2011, Pages 1452-1458

  Costanzi, Stefano ^a   Vilar, Santiago ^a   Micozzi, Daniela ^c   Carpi, Francesco M ^c   Ferino, Giulio ^a   Vita, Alberto ^b   Vincenzetti, Silvia ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF CAMERINO   (Italy)

^c School of Biosciences and Biotechnologies   (Italy)

Author keywords

Cancer; Enzymes; Hydrolases; Inhibitors; Virtual screening

Indexed keywords

CYTIDINE DEAMINASE; IMIDAZOLE NUCLEOSIDE; PROTEIN INHIBITOR; PSEUDOISOCYTIDINE; TETRAHYDRODEOXYURIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; IN VITRO STUDY; INHIBITION KINETICS; MOLECULAR DOCKING; MOUSE; NONHUMAN; NUCLEIC ACID DATABASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BINDING SITES; CYTIDINE; CYTIDINE DEAMINASE; ENZYME INHIBITORS; HUMANS; KINETICS; MICE; MOLECULAR DYNAMICS SIMULATION; NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960686701     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100139     Document Type: Article

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