The effects of oral administration of monosodium glutamate (msg) on the testicular morphology and cauda epididymal sperm reserves of young and adult male rats;Učinci oralnog davanja mononatrijeva glutamata na morfologiju jaja i rezervu spermija u nuzjajčanom repu mladih i odraslih štakora

Veterinarski Arhiv

Volumn 81, Issue 4, 2011, Pages 525-534

  Igwebuike, Udensi M ^a   Ochiogu, Izuchukwu S ^a   Ihedinihu, Blessing C ^a   Ikokide, Joseph E ^a   Idika, Idika K ^a  

^a UNIVERSITY OF NIGERIA   (Nigeria)

Author keywords

Cauda epididymal sperm; Monosodium glutamate; Serum testosterone level; Testicular morphology

Indexed keywords

RATTUS;

EID: 79960680626     PISSN: 03725480     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. AMANN, R. P., J. O. ALMQUIST (1961): Reproductive capacity of dairy bulls. 1. Techniques for direct measurement of gonadal and extra-gonadal sperm reserves. J. Dairy sci. 44, 1537-1545.
2. BURDE, R. M., B. SCHAINKER, J. KAYES (1971): Acute effect of oral and subcutaneous administration of monosodium glutamate on the arcuate nucleus of the hypothalamus in mice and rats. Nature 233, 58-60.
3. DE GENDT K., J. V. SWINNEN, P. T. SAUNDERS, L. SCHOONJANS, M. DEWERCHIN, A. DEVOS, K. TAN, N. ATANASSOVA, F. CLAESSENS, C. LÉCUREUIL, W. HEYNS, P. CARMELIET, F. GUILLOU, R. M. SHARPE, G. VERHOEVEN (2004): A Sertoli cellselective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc. Natl. Acad. Sci. USA 101, 1327-1332.
4. EGBUONU, A. C., O. OBIDOA, C. A. EZEOKONKWO, L. U. EZEANYIKA, P. M. EJIKEME (2009): Hepatotoxic effects of low dose oral administration of monosodium glutamate in male albino rats. African J. Biotechnol. 8, 3031-3035.
5. FAROMBI, E. O., O. O. ONYEMA (2006): Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: modulatory role of vitamin C, vitamin E and guercetin. Human Experimental Toxicol. 125, 251-259.
6. FURST, P., P. STEHLE (2004): What are the essential elements needed for the determination of amino acid requirements in humans? J. Nutri. 34, 1558S-1565S.
7. IGWEBUIKE, U. M., R. I. OBIDIKE, N. U. NJOKU, S. V. O. SHOYINKA (2009): Testicular morphology and epididymal sperm reserves of male rats following the withdrawal of Nigerian Qua Iboe Brent crude oil. Vet. Arhiv 80, 121-128.
8. MCLACHLAN, R. I., N. G. WREFORD, L. O'donnell, D. M. DE KRETSER, D. M. ROBERTSON (1996): The endocrine regulation of spermatogenesis: independent roles for testosterone and FSH. J. Endocrinol. 148, 1-9.
9. NEMEROFF, C. B., C. A. LAMARTINIERE, G. A. MASON, R. E. SQUIBB, J. S. HONG, S. C. BONDY (1981): Marked reduction in gonadal steroid hormone levels in rats treated neonatally with monosodium-L-glutamate: Further evidence for disruption of hypothalamic-pituitarygonadal axis regulation. Neuroendocrinol. 33, 265-267.
10. OBIDIKE, I. R., U. M. IGWEBUIKE, S. V. O. SHOYINKA (2007): Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil. J. Vet. Sci. 8, 1-5.
11. O'shaughnessy, P. J., G. VERHOEVEN, K. DE GENDT, A. MONTEIRO, M. H. ABEL (2010): Direct action through the Sertoli cells is essential for androgen stimulation of spermatogenesis. Endocrinol. 151, 2343-2348.
12. PAKARAINEN, T., F. ZHANG, S. MÄKELÄ, M. POUTANEN, I. HUHTANIEMI (2005): Testosterone replacement therapy induces spermatogenesis and partially restores fertility in luteinizing hormone receptor knockout mice. Endocrinol. 146, 596-606.
13. SAMUELS, A. (1999): The toxicity/safety of MSG: A study in suppression of information. Accountability Res. 6, 259-310.
14. SOHRABI, D., M. ALIPOURB, A. AWSATMELLATIC (2007): Effect of metronidazole on spermatogenesis, plasma gonadotrophins and testosterone in male rats. Iranian J. Pharmaceutical Res. 6, 279-283.
15. URBAN, R. J. (1999): Effects of testosterone and growth hormone on muscle function. J. Lab. Clin. Med. 134, 7-10.
16. WANG, R., S. YEH, C. TZENG, C. CHANG (2009): Androgen receptor roles in spermatogenesis and fertility: Lessons from testicular cell-specific androgen receptor knockout mice. Endocrinol. Rev. 30, 119-132.
17. WITORSCH, R. J. (1995): Reproductive Toxicology, 2nd ed. Raven Press, New York.
18. ZHANG, F., T. PAKARAINEN, M. POUTANEN, J. TOPPARI, I. HUHTANIEMI (2003): The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis. Proc. Natl. Acad. Sci. USA. 100, 13692-13697.
19. ZIRKIN, B. R., R. SANTULLI, C. A. AWONIYI, L. L. EWING (1989): Maintenance of advanced spermatogenic cells in the adult rat testis: quantitative relationship to testosterone concentration within the testis. Endocrinol. 124, 3043-3049.