메뉴 건너뛰기




Volumn 8, Issue 13, 2009, Pages 3031-3035

Hepatotoxic effects of low dose oral administration of monosodium glutamate in male albino rats

Author keywords

Alanine aminotransferase; Alkaline phosphatase; Aspartate aminotransferase; Hepatotoxic effect; Malondialdehyde; Monosodium glutamate

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; GLUTAMATE SODIUM; MALONALDEHYDE;

EID: 67650492511     PISSN: None     EISSN: 16845315     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (46)

References (37)
  • 1
    • 0036218034 scopus 로고    scopus 로고
    • Investigation into the toxicological effects of Catha edulis leaves: A short term study in animals
    • DOI 10.1002/ptr.835
    • Al-Mamary M, Al-Habori M, Al-Aghbari AM, Baker MM (2002). Investigation into the toxicological effects of Catha edulis leaves: a short-term study in animals. Phytoether Res. 16: 127-132. (Pubitemid 34297454)
    • (2002) Phytotherapy Research , vol.16 , Issue.2 , pp. 127-132
    • Al-Mamary, M.1    Al-Habori, M.2    Al-Aghbari, A.M.3    Baker, M.M.4
  • 3
    • 0031766722 scopus 로고    scopus 로고
    • Hyperphagia and weight gain after gold-thioglucose: Relation to hypothalamic neuropeptide Y and proopiomelanocortin
    • DOI 10.1210/en.139.11.4483
    • Bergen HT, Mizuno TM, Taylor J (1998). Hyperphagia and weight gain after gold-thioglucose and monosodium glutamate: relation to hypothalamic neuropeptide. Y. Endocrin. 139: 4483-4488. (Pubitemid 28487763)
    • (1998) Endocrinology , vol.139 , Issue.11 , pp. 4483-4488
    • Bergen, H.T.1    Mizuno, T.M.2    Taylor, J.3    Mobbs, C.V.4
  • 6
    • 0344665686 scopus 로고    scopus 로고
    • Toxicity of hyper caloric diet and monosodium glutamate: Oxidative stress and metabolic shifting in hepatic tissue
    • Diniz YS, Fernando AA, Campos KE, Mani F, Ribas BD, Novelli EL (2004). Toxicity of hyper caloric diet and monosodium glutamate: oxidative stress and metabolic shifting in hepatic tissue. Food Chem. Toxicol. 42: 319-325.
    • (2004) Food Chem. Toxicol. , vol.42 , pp. 319-325
    • Diniz, Y.S.1    Fernando, A.A.2    Campos, K.E.3    Mani, F.4    Ribas, B.D.5    Novelli, E.L.6
  • 7
    • 0042922594 scopus 로고    scopus 로고
    • Monosodium glutamate-sensitive hypothalamic neurons contribute to the control of bone mass
    • DOI 10.1210/en.2003-0369
    • Elefteriou F, Takeda S, Liu X, Armstrong D, Gerard K (2003). Monosodium glutamate-sensitive hypothalamic neurons contribute to the control of bone mass. Endocrin. 144 (9): 3842-3847. (Pubitemid 37088737)
    • (2003) Endocrinology , vol.144 , Issue.9 , pp. 3842-3847
    • Elefteriou, F.1    Takeda, S.2    Liu, X.3    Armstrong, D.4    Karsenty, G.5
  • 8
    • 33744796808 scopus 로고    scopus 로고
    • Monosodium glutamate induced oxidative damage and genotoxicity in rat: Modulatory role of vitamin C, vitamin E and quercetin
    • Farombi EO, Onyema OO (2006). Monosodium glutamate induced oxidative damage and genotoxicity in rat: modulatory role of vitamin C, vitamin E and quercetin. Human Exptl. Toxicol. 25: 251-259.
    • (2006) Human Exptl. Toxicol. , vol.25 , pp. 251-259
    • Farombi, E.O.1    Onyema, O.O.2
  • 9
    • 0035144617 scopus 로고    scopus 로고
    • A comparison of the effect of nitroparacetamol and paracetamol on liver injury
    • Futter IE, Al-Swayeh OA, Moore PK (2001). A comparison of the effect of nitroparacetamol and paracetamol on liver injury. Br. J. Pharmacol. 132: 10-12.
    • (2001) Br. J. Pharmacol. , vol.132 , pp. 10-12
    • Futter, I.E.1    Al-Swayeh, O.A.2    Moore, P.K.3
  • 11
    • 0033551397 scopus 로고    scopus 로고
    • Hypertriaglyceridemia, insulin resistance, and the metabolic syndrome
    • Grundy SM (1999). Hypertriaglyceridemia, insulin resistance, and the metabolic syndrome. Am. J. Cardiol. 83: 25F-29F.
    • (1999) Am. J. Cardiol. , vol.83
    • Grundy, S.M.1
  • 12
    • 0031964325 scopus 로고    scopus 로고
    • Management of dyslipidemia in adults with diabetes (American Diabetes Association position statement)
    • Haffner SM (1998). Management of dyslipidemia in adults with diabetes (American Diabetes Association position statement) Diabetes Care 21: 160-178.
    • (1998) Diabetes Care , vol.21 , pp. 160-178
    • Haffner, S.M.1
  • 13
    • 67650392266 scopus 로고    scopus 로고
    • Available online at
    • Healthnotes MSG (2005). Sensitivity, Available online at: www.healthnotes.com.
    • (2005) Sensitivity
  • 14
    • 2642511931 scopus 로고
    • Ingested sodium glutamate and plasma levels of glutamic acid
    • Himwhich WA, Peterson IM (1954). Ingested sodium glutamate and plasma levels of glutamic acid. J. Appl. Physiol. 7 (2): 196-199.
    • (1954) J. Appl. Physiol. , vol.7 , Issue.2 , pp. 196-199
    • Himwhich, W.A.1    Peterson, I.M.2
  • 15
    • 0033561303 scopus 로고    scopus 로고
    • Special considerations in interpreting Liver function tests
    • Johnston DE (1999). Special considerations in interpreting Liver function tests. Am. Acad. Family Phys. Vol.59 No.8: 2223-2232.
    • (1999) Am. Acad. Family Phys. , vol.59 , Issue.8 , pp. 2223-2232
    • Johnston, D.E.1
  • 17
    • 0027165858 scopus 로고
    • Amino acids as dietary excitotoxins: A contribution to understanding neurodegenerative disorders
    • DOI 10.1016/0165-0173(93)90014-Q
    • Meldrum B (1993). Amino acids as dietary excitotoxins: a contribution to understanding of neurodegenerative disorders. Brain research. Brain research reviews 18 (3): 293-314. (Pubitemid 23219501)
    • (1993) Brain Research Reviews , vol.18 , Issue.3 , pp. 293-314
    • Meldrum, B.1
  • 18
    • 1942470580 scopus 로고    scopus 로고
    • Obesity and changes of alkaline phosphatase activity in the small intestine of 40- 80-day old subjects to early postnatal overfeeding of monosodium glutamate
    • Mozes S, Sefcikova Z, Lenharde L, Raeek L (2004). Obesity and changes of alkaline phosphatase activity in the small intestine of 40- 80-day old subjects to early postnatal overfeeding of monosodium glutamate. Physiol. Res., 53: 177-186.
    • (2004) Physiol. Res. , vol.53 , pp. 177-186
    • Mozes, S.1    Sefcikova, Z.2    Lenharde, L.3    Raeek, L.4
  • 19
    • 64749107495 scopus 로고
    • Monosodium glutamate-induced neurotoxicity: Review of the literature and call for further research
    • edited by Sanford A. Miller (U.S. Food & Drug Administration)
    • Nemeroff C (1980). Monosodium glutamate-induced neurotoxicity: Review of the literature and call for further research. Nutrition & Behavior edited by Sanford A. Miller (U.S. Food & Drug Administration): p. 177-211.
    • (1980) Nutrition & Behavior , pp. 177-211
    • Nemeroff, C.1
  • 21
    • 0014668762 scopus 로고
    • Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate
    • Olney JN (1969). Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Sci. 164: 719-721.
    • (1969) Sci. , vol.164 , pp. 719-721
    • Olney, J.N.1
  • 23
    • 66349129125 scopus 로고
    • A colorimetric method for the determination of serum glutamate oxaloacetate and pyruvate transaminase
    • Reitman S, Frankel S (1957). A colorimetric method for the determination of serum glutamate oxaloacetate and pyruvate transaminase. Am. J. Clin. Pathol., 28: 56-63.
    • (1957) Am. J. Clin. Pathol. , vol.28 , pp. 56-63
    • Reitman, S.1    Frankel, S.2
  • 24
    • 77955558553 scopus 로고    scopus 로고
    • Enzymes: Mechanism of action
    • Murray, R.K., Granner, D.K., Mayes, P.A. and Rodwell, V.W. ed Lange Medical Books/McGraw-Hill, New York. chap 7
    • Rodwell VW, Kennelly PJ (2003). Enzymes: Mechanism of action In: Murray, R.K., Granner, D.K., Mayes, P.A. and Rodwell, V.W. ed Harper's Illustrated Biochemistry 26th edn Lange Medical Books/McGraw-Hill, New York. chap 7, p. 57.
    • (2003) Harper's Illustrated Biochemistry 26th Edn , pp. 57
    • Rodwell, V.W.1    Kennelly, P.J.2
  • 25
    • 0014686294 scopus 로고
    • Monosodium L-glutamate, its pharmacology and role in the Chinese restaurant syndrome
    • Schaumberg HH, Byck R, Gerst R, Mashman JH (1969). Monosodium L-glutamate, its pharmacology and role in the Chinese restaurant syndrome. Sci. 163: 826-828.
    • (1969) Sci. , vol.163 , pp. 826-828
    • Schaumberg, H.H.1    Byck, R.2    Gerst, R.3    Mashman, J.H.4
  • 26
    • 84947410804 scopus 로고
    • An analysis of variance for paired comparisons
    • Scheffe H (1952). An analysis of variance for paired comparisons. J. Am. Statistics Assoc., 47: 38-400.
    • (1952) J. Am. Statistics Assoc. , vol.47 , pp. 38-400
    • Scheffe, H.1
  • 27
    • 67650370341 scopus 로고
    • Collecting and handling blood for laboratory study
    • Lea and Febiger, Philadelphia
    • Scholm, O. W., Tain, N. C. and Corrall E. J. (1975). Collecting and handling blood for laboratory study In: Scholm Vet. Haematol., Lea and Febiger, Philadelphia. pp. 9-25.
    • (1975) Scholm Vet. Haematol. , pp. 9-25
    • Scholm, O.W.1    Tain, N.C.2    Corrall, E.J.3
  • 28
    • 0022389262 scopus 로고
    • Plasma glutamate concentrations in adult subjects ingesting monosodium L-glutamate in consomme
    • Stegink LD, Filer Jr LJ, Baker GL (1985). Plasma glutamate concentrations in adult subjects ingesting monosodium L-glutamate in consomme. Am. J. Clin. Nutr. 42: 220-225.
    • (1985) Am. J. Clin. Nutr. , vol.42 , pp. 220-225
    • Stegink, L.D.1    Filer Jr., L.J.2    Baker, G.L.3
  • 29
    • 0023583117 scopus 로고
    • Plasma amino acid concentrations in normal adults ingesting aspartame and monosodium L-glutamate as part of a soup/beverage meal
    • Stegink LD, Filer Jr LJ, Baker GL (1987). Plasma amino acid concentrations in normal adults ingesting aspartame and monosodium L-glutamate as part of a soup/beverage meal Metabolism 36(11): 1073-1079.
    • (1987) Metabolism , vol.36 , Issue.11 , pp. 1073-1079
    • Stegink, L.D.1    Filer Jr., L.J.2    Baker, G.L.3
  • 30
    • 67650365043 scopus 로고    scopus 로고
    • (a) June, 2, Available online at
    • TILC (Truth In Labeling Campaign)(a). (June, 2, 2004). Neuroendocrine disorders. Available online at: www.truthinlabeling.org
    • (2004) Neuroendocrine Disorders
  • 31
    • 67650377229 scopus 로고    scopus 로고
    • (b) July, 3, Available online at
    • TILC (Truth In Labeling Campaign) (b). (July, 3, 2004). Learning and memory disorder. Available online at: www.truthinlabeing.org.
    • (2004) Learning and Memory Disorder
  • 32
    • 0032572572 scopus 로고    scopus 로고
    • Hepatotoxicity of non-narcotic analgesics
    • Tolman KG (1998. Hepatotoxicity of non-narcotic analgesics. Am. J. Med. 27: 13S-19S.
    • (1998) Am. J. Med. , vol.27
    • Tolman, K.G.1
  • 33
    • 0028314498 scopus 로고
    • Effect of paraquat on the malondialdehyde level in rats liver microsome (in vitro)
    • Tomita M, Okuyama T (1994). Effect of paraquat on the malondialdehyde level in rats liver microsome (in vitro). Arch. Toxicol. 68: 187-192.
    • (1994) Arch. Toxicol. , vol.68 , pp. 187-192
    • Tomita, M.1    Okuyama, T.2
  • 34
    • 0034065937 scopus 로고    scopus 로고
    • The safety evaluation of monosodium glutamate
    • Walker R, Lupien JR (2000). The safety evaluation of monosodium glutamate. J. Nutr. 130 (4S suppl): 1049-1052S.
    • (2000) J. Nutr. , vol.130 , Issue.4 S SUPPL.
    • Walker, R.1    Lupien, J.R.2
  • 35
    • 0027399578 scopus 로고
    • Lipid oxidation and measurement of thiobarbituric acid reacting substances (TBARS) formation in a single microtitre plate: Its use for evaluation of antioxidants
    • Wallin B, Rosengren B, Shetzer HG, Cameja G (1993). Lipid oxidation and measurement of thiobarbituric acid reacting substances (TBARS) formation in a single microtitre plate: its use for evaluation of antioxidants. Anal. Biochem. 208: 10-15.
    • (1993) Anal. Biochem. , vol.208 , pp. 10-15
    • Wallin, B.1    Rosengren, B.2    Shetzer, H.G.3    Cameja, G.4
  • 36
    • 0000831015 scopus 로고
    • Alkaline Phosphatase in serum (Continuous Assay Method)
    • Hans Ulrich Bergmeyer (Ed)
    • Walter K, Schutt C (1974). Alkaline Phosphatase in serum (Continuous Assay Method). In: Hans Ulrich Bergmeyer (Ed) Methods of Enzymatic Analysis. 2nd edn. Vol.2: 856-870.
    • (1974) Methods of Enzymatic Analysis. 2nd Edn. , vol.2 , pp. 856-870
    • Walter, K.1    Schutt, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.