-
2
-
-
6044269157
-
Self-renewal of teratocarcinoma and embryonic stem cells
-
Chambers I., Smith A. Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 2004, 23:7150-7160.
-
(2004)
Oncogene
, vol.23
, pp. 7150-7160
-
-
Chambers, I.1
Smith, A.2
-
3
-
-
48049098134
-
Molecular basis of pluripotency
-
Chen L., Daley G.Q. Molecular basis of pluripotency. Hum Mol Genet 2008, 17:R23-R27.
-
(2008)
Hum Mol Genet
, vol.17
-
-
Chen, L.1
Daley, G.Q.2
-
4
-
-
68549133583
-
Mapping key features of transcriptional regulatory circuitry in embryonic stem cells
-
Cole M.F., Young R.A. Mapping key features of transcriptional regulatory circuitry in embryonic stem cells. Cold Spring Harb Symp Quant Biol 2008, 73:183-193.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 183-193
-
-
Cole, M.F.1
Young, R.A.2
-
5
-
-
68549104469
-
The transcriptional network controlling pluripotency in ES cells
-
Orkin S.H., Wang J., Kim J., et al. The transcriptional network controlling pluripotency in ES cells. Cold Spring Harb Symp Quant Biol 2008, 73:195-202.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 195-202
-
-
Orkin, S.H.1
Wang, J.2
Kim, J.3
-
6
-
-
33846184752
-
Nanog and transcriptional networks in embryonic stem cell pluripotency
-
Pan G., Thomson J.A. Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res 2007, 17:42-49.
-
(2007)
Cell Res
, vol.17
, pp. 42-49
-
-
Pan, G.1
Thomson, J.A.2
-
7
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., Tanabe K., Ohnuki M., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
8
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park I.H., Zhao R., West J.A., et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008, 451:141-146.
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
-
9
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J., Vodyanik M.A., Smuga-Otto K., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318:1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
10
-
-
75349088911
-
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells
-
Heng J.C., Feng B., Han J., et al. The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell 2010, 6:167-174.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.C.1
Feng, B.2
Han, J.3
-
11
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa M., Koyanagi M., Tanabe K., et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008, 26:101-106.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
-
12
-
-
28844450086
-
Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin
-
Andrews P.W., Matin M.M., Bahrami A.R., Damjanov I., Gokhale P., Draper J.S. Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin. Biochem Soc Trans 2005, 33:1526-1530.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 1526-1530
-
-
Andrews, P.W.1
Matin, M.M.2
Bahrami, A.R.3
Damjanov, I.4
Gokhale, P.5
Draper, J.S.6
-
13
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., et al. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282:1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
-
14
-
-
60149084519
-
PASTAA: identifying transcription factors associated with sets of co-regulated genes
-
Roider H.G., Manke T., O'Keeffe S., Vingron M., Haas S.A. PASTAA: identifying transcription factors associated with sets of co-regulated genes. Bioinformatics 2009, 25:435-442.
-
(2009)
Bioinformatics
, vol.25
, pp. 435-442
-
-
Roider, H.G.1
Manke, T.2
O'Keeffe, S.3
Vingron, M.4
Haas, S.A.5
-
15
-
-
34447295350
-
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
-
International Stem Cell Initiative
-
Adewumi O., Aflatoonian B., et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol 2007, 25:803-816. International Stem Cell Initiative.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 803-816
-
-
Adewumi, O.1
Aflatoonian, B.2
-
16
-
-
47949130484
-
Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells
-
O'Connor M.D., Kardel M.D., Iosfina I., et al. Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells. Stem Cells 2008, 26:1109-1116.
-
(2008)
Stem Cells
, vol.26
, pp. 1109-1116
-
-
O'Connor, M.D.1
Kardel, M.D.2
Iosfina, I.3
-
18
-
-
33846000624
-
Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines
-
Khattra J., Delaney A.D., Zhao Y., et al. Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines. Genome Res 2007, 17:108-116.
-
(2007)
Genome Res
, vol.17
, pp. 108-116
-
-
Khattra, J.1
Delaney, A.D.2
Zhao, Y.3
-
19
-
-
70349636603
-
Next-generation tag sequencing for cancer gene expression profiling
-
Morrissy A.S., Morin R.D., Delaney A., et al. Next-generation tag sequencing for cancer gene expression profiling. Genome Res 2009, 19:1825-1835.
-
(2009)
Genome Res
, vol.19
, pp. 1825-1835
-
-
Morrissy, A.S.1
Morin, R.D.2
Delaney, A.3
-
21
-
-
52649149771
-
A seriation approach for visualization-driven discovery of co-expression patterns in Serial Analysis of Gene Expression (SAGE) data
-
Morozova O., Morozov V., Hoffman B.G., Helgason C.D., Marra M.A. A seriation approach for visualization-driven discovery of co-expression patterns in Serial Analysis of Gene Expression (SAGE) data. PLoS One 2008, 3:e3205.
-
(2008)
PLoS One
, vol.3
-
-
Morozova, O.1
Morozov, V.2
Hoffman, B.G.3
Helgason, C.D.4
Marra, M.A.5
-
22
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009, 4:44-57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
23
-
-
33646361583
-
GenePattern 2.0
-
Reich M., Liefeld T., Gould J., Lerner J., Tamayo P., Mesirov J.P. GenePattern 2.0. Nat Genet 2006, 38:500-501.
-
(2006)
Nat Genet
, vol.38
, pp. 500-501
-
-
Reich, M.1
Liefeld, T.2
Gould, J.3
Lerner, J.4
Tamayo, P.5
Mesirov, J.P.6
-
24
-
-
0001677717
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 1995, 57:289-300.
-
(1995)
J R Stat Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
25
-
-
33646856541
-
-
John Wiley & Sons, Hoboken, NJ
-
Van Belle G., Fisher L.D., Heagerty P.J., Lumley T. Biostatistics: a methodology for the health sciences 2004, John Wiley & Sons, Hoboken, NJ.
-
(2004)
Biostatistics: a methodology for the health sciences
-
-
Van Belle, G.1
Fisher, L.D.2
Heagerty, P.J.3
Lumley, T.4
-
26
-
-
39549084088
-
LongSAGE profiling of nine human embryonic stem cell lines
-
Hirst M., Delaney A., Rogers S.A., et al. LongSAGE profiling of nine human embryonic stem cell lines. Genome Biol 2007, 8:R113.
-
(2007)
Genome Biol
, vol.8
-
-
Hirst, M.1
Delaney, A.2
Rogers, S.A.3
-
27
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer L.A., Lee T.I., Cole M.F., et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005, 122:947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
-
28
-
-
35949000033
-
A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members
-
Xu X., Bieda M., Jin V.X., et al. A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members. Genome Res 2007, 17:1550-1561.
-
(2007)
Genome Res
, vol.17
, pp. 1550-1561
-
-
Xu, X.1
Bieda, M.2
Jin, V.X.3
-
29
-
-
33746773659
-
Dissecting self-renewal in stem cells with RNA interference
-
Ivanova N., Dobrin R., Lu R., et al. Dissecting self-renewal in stem cells with RNA interference. Nature 2006, 442:533-538.
-
(2006)
Nature
, vol.442
, pp. 533-538
-
-
Ivanova, N.1
Dobrin, R.2
Lu, R.3
-
30
-
-
18344393150
-
The E2F transcriptional network: old acquaintances with new faces
-
Dimova D.K., Dyson N.J. The E2F transcriptional network: old acquaintances with new faces. Oncogene 2005, 24:2810-2826.
-
(2005)
Oncogene
, vol.24
, pp. 2810-2826
-
-
Dimova, D.K.1
Dyson, N.J.2
-
31
-
-
0028157458
-
Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts
-
Savatier P., Huang S., Szekely L., Wiman K.G., Samarut J. Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts. Oncogene 1994, 9:809-818.
-
(1994)
Oncogene
, vol.9
, pp. 809-818
-
-
Savatier, P.1
Huang, S.2
Szekely, L.3
Wiman, K.G.4
Samarut, J.5
-
32
-
-
33744975288
-
Cell cycle features of primate embryonic stem cells
-
Fluckiger A.C., Marcy G., Marchand M., et al. Cell cycle features of primate embryonic stem cells. Stem Cells 2006, 24:547-556.
-
(2006)
Stem Cells
, vol.24
, pp. 547-556
-
-
Fluckiger, A.C.1
Marcy, G.2
Marchand, M.3
-
33
-
-
37049022559
-
Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells
-
Filipczyk A.A., Laslett A.L., Mummery C., Pera M.F. Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells. Stem Cell Res 2007, 1:45-60.
-
(2007)
Stem Cell Res
, vol.1
, pp. 45-60
-
-
Filipczyk, A.A.1
Laslett, A.L.2
Mummery, C.3
Pera, M.F.4
-
34
-
-
68649109365
-
Regulatory circuits underlying pluripotency and reprogramming
-
Do J.T., Scholer H.R. Regulatory circuits underlying pluripotency and reprogramming. Trends Pharmacol Sci 2009, 30:296-302.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 296-302
-
-
Do, J.T.1
Scholer, H.R.2
-
35
-
-
34247264419
-
Zic3 is required for maintenance of pluripotency in embryonic stem cells
-
Lim L.S., Loh Y.H., Zhang W., et al. Zic3 is required for maintenance of pluripotency in embryonic stem cells. Mol Biol Cell 2007, 18:1348-1358.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1348-1358
-
-
Lim, L.S.1
Loh, Y.H.2
Zhang, W.3
-
36
-
-
0037070599
-
Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro
-
He W., Gong K., Zhu G., Smith D.K., Ip N.Y. Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro. FEBS Lett 2002, 514:214-218.
-
(2002)
FEBS Lett
, vol.514
, pp. 214-218
-
-
He, W.1
Gong, K.2
Zhu, G.3
Smith, D.K.4
Ip, N.Y.5
-
37
-
-
62149096747
-
The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells
-
Blum B., Bar-Nur O., Golan-Lev T., Benvenisty N. The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells. Nat Biotechnol 2009, 27:281-287.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 281-287
-
-
Blum, B.1
Bar-Nur, O.2
Golan-Lev, T.3
Benvenisty, N.4
-
38
-
-
0031870964
-
A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability
-
Woitach J.T., Zhang M., Niu C.H., Thorgeirsson S.S. A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability. Nat Genet 1998, 19:371-374.
-
(1998)
Nat Genet
, vol.19
, pp. 371-374
-
-
Woitach, J.T.1
Zhang, M.2
Niu, C.H.3
Thorgeirsson, S.S.4
-
39
-
-
33745140886
-
Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome
-
Bieda M., Xu X., Singer M.A., Green R., Farnham P.J. Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome. Genome Res 2006, 16:595-605.
-
(2006)
Genome Res
, vol.16
, pp. 595-605
-
-
Bieda, M.1
Xu, X.2
Singer, M.A.3
Green, R.4
Farnham, P.J.5
-
40
-
-
37549016756
-
Specific in vivo roles for E2Fs in differentiation and development
-
McClellan K.A., Slack R.S. Specific in vivo roles for E2Fs in differentiation and development. Cell Cycle 2007, 6:2917-2927.
-
(2007)
Cell Cycle
, vol.6
, pp. 2917-2927
-
-
McClellan, K.A.1
Slack, R.S.2
-
41
-
-
0033635597
-
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
-
Dannenberg J.H., van Rossum A., Schuijff L., te Riele H. Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev 2000, 14:3051-3064.
-
(2000)
Genes Dev
, vol.14
, pp. 3051-3064
-
-
Dannenberg, J.H.1
van Rossum, A.2
Schuijff, L.3
te Riele, H.4
-
42
-
-
79151470981
-
A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity
-
Ruiz S., Panopoulos A.D., Herrerias A., et al. A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity. Curr Biol 2011, 21:45-52.
-
(2011)
Curr Biol
, vol.21
, pp. 45-52
-
-
Ruiz, S.1
Panopoulos, A.D.2
Herrerias, A.3
-
43
-
-
0027320814
-
A retinoblastoma-binding protein related to a negative regulator of Ras in yeast
-
Qian Y.W., Wang Y.C., Hollingsworth R.E., Jones D., Ling N., Lee E.Y. A retinoblastoma-binding protein related to a negative regulator of Ras in yeast. Nature 1993, 364:648-652.
-
(1993)
Nature
, vol.364
, pp. 648-652
-
-
Qian, Y.W.1
Wang, Y.C.2
Hollingsworth, R.E.3
Jones, D.4
Ling, N.5
Lee, E.Y.6
-
44
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen X., Xu H., Yuan P., et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008, 133:1106-1117.
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
-
45
-
-
52149097555
-
Regulatory networks define phenotypic classes of human stem cell lines
-
Muller F.J., Laurent L.C., Kostka D., et al. Regulatory networks define phenotypic classes of human stem cell lines. Nature 2008, 455:401-405.
-
(2008)
Nature
, vol.455
, pp. 401-405
-
-
Muller, F.J.1
Laurent, L.C.2
Kostka, D.3
-
46
-
-
74949138014
-
Exhaustive search for over-represented DNA sequence motifs with CisFinder
-
Sharov A.A., Ko M.S. Exhaustive search for over-represented DNA sequence motifs with CisFinder. DNA Res 2009, 16:261-273.
-
(2009)
DNA Res
, vol.16
, pp. 261-273
-
-
Sharov, A.A.1
Ko, M.S.2
-
47
-
-
0026719682
-
Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription factor ATF-2
-
Kim S.J., Wagner S., Liu F., O'Reilly M.A., Robbins P.D., Green M.R. Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription factor ATF-2. Nature 1992, 358:331-334.
-
(1992)
Nature
, vol.358
, pp. 331-334
-
-
Kim, S.J.1
Wagner, S.2
Liu, F.3
O'Reilly, M.A.4
Robbins, P.D.5
Green, M.R.6
-
48
-
-
0037111831
-
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
-
Kuzmichev A., Nishioka K., Erdjument-Bromage H., Tempst P., Reinberg D. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev 2002, 16:2893-2905.
-
(2002)
Genes Dev
, vol.16
, pp. 2893-2905
-
-
Kuzmichev, A.1
Nishioka, K.2
Erdjument-Bromage, H.3
Tempst, P.4
Reinberg, D.5
-
49
-
-
0033180082
-
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
-
Zhang Y., Ng H.H., Erdjument-Bromage H., Tempst P., Bird A., Reinberg D. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev 1999, 13:1924-1935.
-
(1999)
Genes Dev
, vol.13
, pp. 1924-1935
-
-
Zhang, Y.1
Ng, H.H.2
Erdjument-Bromage, H.3
Tempst, P.4
Bird, A.5
Reinberg, D.6
-
50
-
-
33751092246
-
A protein interaction network for pluripotency of embryonic stem cells
-
Wang J., Rao S., Chu J., et al. A protein interaction network for pluripotency of embryonic stem cells. Nature 2006, 444:364-368.
-
(2006)
Nature
, vol.444
, pp. 364-368
-
-
Wang, J.1
Rao, S.2
Chu, J.3
-
51
-
-
44649086468
-
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
-
Liang J., Wan M., Zhang Y., et al. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol 2008, 10:731-739.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 731-739
-
-
Liang, J.1
Wan, M.2
Zhang, Y.3
-
52
-
-
64349085775
-
Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes
-
Bachovchin D.A., Brown S.J., Rosen H., Cravatt B.F. Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes. Nat Biotechnol 2009, 27:387-394.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 387-394
-
-
Bachovchin, D.A.1
Brown, S.J.2
Rosen, H.3
Cravatt, B.F.4
|