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Volumn 322, Issue 1, 2011, Pages 41-50

Toxin-antitoxin (TA) systems are prevalent and transcribed in clinical isolates of Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus

Author keywords

Antibacterial; MazEF; Plasmid addiction; RelBE

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; GENE LOCATION; GENETIC TRANSCRIPTION; HIGBA GENE; MAZEF GENE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTIPLE LOCUS VARIABLE NUMBER OF TANDEM REPEATS ANALYSIS; NONHUMAN; PARDE GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RELBE GENE; TANDEM REPEAT; TOXIN ANTITOXIN GENE;

EID: 79960625546     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2011.02330.x     Document Type: Article
Times cited : (50)

References (37)
  • 1
    • 67651103123 scopus 로고    scopus 로고
    • Bacterial toxin-antitoxin systems as targets for the development of novel antibiotics
    • Bonomo RA & Tomalsky ME, eds) American Society for Microbiology Press, Washington, DC.
    • Alonso JC, Balsa D, Cherny I, et al. (2007) Bacterial toxin-antitoxin systems as targets for the development of novel antibiotics. Enzyme-Mediated Resistance to Antibiotics: Mechanisms, Dissemination, and Prospects for Inhibition (Bonomo RA & Tomalsky ME, eds), pp. 313-329. American Society for Microbiology Press, Washington, DC.
    • (2007) Enzyme-Mediated Resistance to Antibiotics: Mechanisms, Dissemination, and Prospects for Inhibition , pp. 313-329
    • Alonso, J.C.1    Balsa, D.2    Cherny, I.3
  • 2
    • 10044283095 scopus 로고    scopus 로고
    • MazF-mediated cell death in Escherichia coli: a point of no return
    • Amitai S, Yassin Y & Engelberg-Kulka H (2004) MazF-mediated cell death in Escherichia coli: a point of no return. J Bacteriol 186: 8295-8300.
    • (2004) J Bacteriol. , vol.186 , pp. 8295-8300
    • Amitai, S.1    Yassin, Y.2    Engelberg-Kulka, H.3
  • 3
    • 33846200333 scopus 로고    scopus 로고
    • Characterization of a higBA toxin-antitoxin locus in Vibrio cholerae
    • Budde PP, Davis BM, Yuan J & Waldor MK (2007) Characterization of a higBA toxin-antitoxin locus in Vibrio cholerae. J Bacteriol 189: 491-500.
    • (2007) J Bacteriol , vol.189 , pp. 491-500
    • Budde, P.P.1    Davis, B.M.2    Yuan, J.3    Waldor, M.K.4
  • 4
    • 27944437497 scopus 로고    scopus 로고
    • Toxin-antitoxin modules as bacterial metabolic stress managers
    • Buts L, Lah J, Dao-Thi MH, Wyns L & Loris R (2005) Toxin-antitoxin modules as bacterial metabolic stress managers. Trends Biochem Sci 30: 672-679.
    • (2005) Trends Biochem Sci , vol.30 , pp. 672-679
    • Buts, L.1    Lah, J.2    Dao-Thi, M.H.3    Wyns, L.4    Loris, R.5
  • 5
    • 0035807805 scopus 로고    scopus 로고
    • RelE, a global inhibitor of translation, is activated during nutritional stress
    • Christensen SK, Mikkelsen M, Pedersen K & Gerdes K (2001) RelE, a global inhibitor of translation, is activated during nutritional stress. P Natl Acad Sci USA 98: 14328-14333.
    • (2001) P Natl Acad Sci USA , vol.98 , pp. 14328-14333
    • Christensen, S.K.1    Mikkelsen, M.2    Pedersen, K.3    Gerdes, K.4
  • 6
    • 0041825422 scopus 로고    scopus 로고
    • Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA
    • Christensen SK, Pedersen K, Hansen FG & Gerdes K (2003) Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA. J Mol Biol 332: 809-819.
    • (2003) J Mol Biol. , vol.332 , pp. 809-819
    • Christensen, S.K.1    Pedersen, K.2    Hansen, F.G.3    Gerdes, K.4
  • 7
    • 1642483754 scopus 로고    scopus 로고
    • Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system
    • Christensen SK, Maenhaut-Michel G, Mine N, Gottesman S, Gerdes K & Van Melderen L (2004) Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system. Mol Microbiol 51: 1705-1717.
    • (2004) Mol Microbiol. , vol.51 , pp. 1705-1717
    • Christensen, S.K.1    Maenhaut-Michel, G.2    Mine, N.3    Gottesman, S.4    Gerdes, K.5    Van Melderen, L.6
  • 8
    • 33749178742 scopus 로고    scopus 로고
    • Two higBA loci in the Vibrio cholerae superintegron encode mRNA cleaving enzymes and can stabilize plasmids
    • Christensen-Dalsgaard M & Gerdes K (2006) Two higBA loci in the Vibrio cholerae superintegron encode mRNA cleaving enzymes and can stabilize plasmids. Mol Microbiol 62: 397-411.
    • (2006) Mol Microbiol , vol.62 , pp. 397-411
    • Christensen-Dalsgaard, M.1    Gerdes, K.2
  • 9
    • 16244380517 scopus 로고    scopus 로고
    • Bacterial death comes full circle: targeting plasmid replication in drug-resistant bacteria
    • DeNap JC & Hergenrother PJ (2005) Bacterial death comes full circle: targeting plasmid replication in drug-resistant bacteria. Org Biomol Chem 3: 959-966.
    • (2005) Org Biomol Chem. , vol.3 , pp. 959-966
    • DeNap, J.C.1    Hergenrother, P.J.2
  • 10
    • 65249145128 scopus 로고    scopus 로고
    • Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression
    • Donegan NP & Cheung AL (2009) Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression. J Bacteriol 191: 2795-2805.
    • (2009) J Bacteriol , vol.191 , pp. 2795-2805
    • Donegan, N.P.1    Cheung, A.L.2
  • 14
    • 64049118002 scopus 로고    scopus 로고
    • Sa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage
    • Sa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage. J Bacteriol 191: 2051-2059.
    • (2009) J Bacteriol , vol.191 , pp. 2051-2059
    • Fu, Z.1    Tamber, S.2    Memmi, G.3    Donegan, N.P.4    Cheung, A.L.5
  • 15
    • 0345333119 scopus 로고
    • Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells
    • Gerdes K, Rasmussen PB & Molin S (1986) Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells. P Natl Acad Sci USA 83: 3116-3120.
    • (1986) P Natl Acad Sci USA. , vol.83 , pp. 3116-3120
    • Gerdes, K.1    Rasmussen, P.B.2    Molin, S.3
  • 17
    • 77954408888 scopus 로고    scopus 로고
    • The Yersinia pestis chromosome encodes active addiction toxins
    • Goulard C, Langrand S, Carniel E & Chauvaux S (2010) The Yersinia pestis chromosome encodes active addiction toxins. J Bacteriol 192: 3669-3677.
    • (2010) J Bacteriol , vol.192 , pp. 3669-3677
    • Goulard, C.1    Langrand, S.2    Carniel, E.3    Chauvaux, S.4
  • 18
    • 79951469344 scopus 로고    scopus 로고
    • Txe, an endoribonuclease of the enterococcal Axe-Txe toxin-antitoxin system, cleaves mRNA and inhibits protein synthesis
    • Halvorsen EM, Williams JJ, Bhimani AJ, Billings EA & Hergenrother PJ (2011) Txe, an endoribonuclease of the enterococcal Axe-Txe toxin-antitoxin system, cleaves mRNA and inhibits protein synthesis. Microbiology 157: 387-397.
    • (2011) Microbiology , vol.157 , pp. 387-397
    • Halvorsen, E.M.1    Williams, J.J.2    Bhimani, A.J.3    Billings, E.A.4    Hergenrother, P.J.5
  • 19
    • 0141707105 scopus 로고    scopus 로고
    • Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest
    • Hayes F (2003) Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest. Science 301: 1496-1499.
    • (2003) Science. , vol.301 , pp. 1496-1499
    • Hayes, F.1
  • 20
    • 67650517830 scopus 로고    scopus 로고
    • Bacterial toxin HigB associates with ribosomes and mediates translation-dependent mRNA cleavage at A-rich sites
    • Hurley JM & Woychik NA (2009) Bacterial toxin HigB associates with ribosomes and mediates translation-dependent mRNA cleavage at A-rich sites. J Biol Chem 284: 18605-18613.
    • (2009) J Biol Chem , vol.284 , pp. 18605-18613
    • Hurley, J.M.1    Woychik, N.A.2
  • 21
    • 10044266575 scopus 로고    scopus 로고
    • Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
    • Keren I, Shah D, Spoering A, Kaldalu N & Lewis K (2004) Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J Bacteriol 186: 8172-8180.
    • (2004) J Bacteriol , vol.186 , pp. 8172-8180
    • Keren, I.1    Shah, D.2    Spoering, A.3    Kaldalu, N.4    Lewis, K.5
  • 22
    • 67649933665 scopus 로고    scopus 로고
    • Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes
    • Makarova KS, Wolf YI & Koonin EV (2009) Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes. Biol Direct 4: 19.
    • (2009) Biol Direct , vol.4 , pp. 19
    • Makarova, K.S.1    Wolf, Y.I.2    Koonin, E.V.3
  • 23
    • 33846064688 scopus 로고    scopus 로고
    • Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci
    • Moritz EM & Hergenrother PJ (2007) Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci. P Natl Acad Sci USA 104: 311-316.
    • (2007) P Natl Acad Sci USA , vol.104 , pp. 311-316
    • Moritz, E.M.1    Hergenrother, P.J.2
  • 24
    • 22544441350 scopus 로고    scopus 로고
    • Iron salts perturb biofilm formation and disrupt existing biofilms of Pseudomonas aeruginosa
    • Musk DJ, Banko DA & Hergenrother PJ (2005) Iron salts perturb biofilm formation and disrupt existing biofilms of Pseudomonas aeruginosa. Chem Biol 12: 789-796.
    • (2005) Chem Biol , vol.12 , pp. 789-796
    • Musk, D.J.1    Banko, D.A.2    Hergenrother, P.J.3
  • 25
    • 37649005671 scopus 로고    scopus 로고
    • MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development
    • Nariya H & Inouye M (2008) MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development. Cell 132: 55-66.
    • (2008) Cell , vol.132 , pp. 55-66
    • Nariya, H.1    Inouye, M.2
  • 26
    • 33645072739 scopus 로고    scopus 로고
    • The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interaction
    • Nieto C, Pellicer T, Balsa D, Christensen SK, Gerdes K & Espinosa M (2006) The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interaction. Mol Microbiol 59: 1280-1296.
    • (2006) Mol Microbiol. , vol.59 , pp. 1280-1296
    • Nieto, C.1    Pellicer, T.2    Balsa, D.3    Christensen, S.K.4    Gerdes, K.5    Espinosa, M.6
  • 27
    • 14244266086 scopus 로고    scopus 로고
    • Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes
    • Pandey DP & Gerdes K (2005) Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res 33: 966-976.
    • (2005) Nucleic Acids Res , vol.33 , pp. 966-976
    • Pandey, D.P.1    Gerdes, K.2
  • 28
    • 0036067108 scopus 로고    scopus 로고
    • Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins
    • Pedersen K, Christensen SK & Gerdes K (2002) Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol Microbiol 45: 501-510.
    • (2002) Mol Microbiol , vol.45 , pp. 501-510
    • Pedersen, K.1    Christensen, S.K.2    Gerdes, K.3
  • 29
    • 0037428226 scopus 로고    scopus 로고
    • The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site
    • Pedersen K, Zavialov AV, Pavlov MY, Elf J, Gerdes K & Ehrenberg M (2003) The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell 112: 131-140.
    • (2003) Cell , vol.112 , pp. 131-140
    • Pedersen, K.1    Zavialov, A.V.2    Pavlov, M.Y.3    Elf, J.4    Gerdes, K.5    Ehrenberg, M.6
  • 30
    • 12444304190 scopus 로고    scopus 로고
    • New method for typing Staphylococcus aureus strains: multiple-locus variable-number tandem repeat analysis of polymorphism and genetic relationships of clinical isolates
    • Sabat A, Krzyszton-Russjan J, Strzalka W, Filipek R, Kosowska K, Hryniewicz W, Travis J & Potempa J (2003) New method for typing Staphylococcus aureus strains: multiple-locus variable-number tandem repeat analysis of polymorphism and genetic relationships of clinical isolates. J Clin Microbiol 41: 1801-1804.
    • (2003) J Clin Microbiol. , vol.41 , pp. 1801-1804
    • Sabat, A.1    Krzyszton-Russjan, J.2    Strzalka, W.3    Filipek, R.4    Kosowska, K.5    Hryniewicz, W.6    Travis, J.7    Potempa, J.8
  • 31
    • 33846600362 scopus 로고    scopus 로고
    • Comparative DNA analysis of two vanA plasmids from Enterococcus faecium strains isolated from poultry and a poultry farmer in Norway
    • Sletvold H, Johnsen PJ, Simonsen GS, Aasnaes B, Sundsfjord A & Nielsen KM (2007) Comparative DNA analysis of two vanA plasmids from Enterococcus faecium strains isolated from poultry and a poultry farmer in Norway. Antimicrob Agents Ch 51: 736-739.
    • (2007) Antimicrob Agents Ch , vol.51 , pp. 736-739
    • Sletvold, H.1    Johnsen, P.J.2    Simonsen, G.S.3    Aasnaes, B.4    Sundsfjord, A.5    Nielsen, K.M.6
  • 32
    • 33947330447 scopus 로고    scopus 로고
    • Chromosomal toxin-antitoxin loci can diminish large-scale genome reductions in the absence of selection
    • Szekeres S, Dauti M, Wilde C, Mazel D & Rowe-Magnus DA (2007) Chromosomal toxin-antitoxin loci can diminish large-scale genome reductions in the absence of selection. Mol Microbiol 63: 1588-1605.
    • (2007) Mol Microbiol , vol.63 , pp. 1588-1605
    • Szekeres, S.1    Dauti, M.2    Wilde, C.3    Mazel, D.4    Rowe-Magnus, D.A.5
  • 33
    • 35348921837 scopus 로고    scopus 로고
    • Multiple-locus variable-number tandem-repeat analysis for longitudinal survey of sources of Pseudomonas aeruginosa infection in cystic fibrosis patients
    • Vu-Thien H, Corbineau G, Hormigos K, Fauroux B, Corvol H, Clement A, Vergnaud G & Pourcel C (2007) Multiple-locus variable-number tandem-repeat analysis for longitudinal survey of sources of Pseudomonas aeruginosa infection in cystic fibrosis patients. J Clin Microbiol 45: 3175-3183.
    • (2007) J Clin Microbiol , vol.45 , pp. 3175-3183
    • Vu-Thien, H.1    Corbineau, G.2    Hormigos, K.3    Fauroux, B.4    Corvol, H.5    Clement, A.6    Vergnaud, G.7    Pourcel, C.8
  • 34
    • 50449110851 scopus 로고    scopus 로고
    • Exposing plasmids as the Achilles' heel of drug-resistant bacteria
    • Williams JJ & Hergenrother PJ (2008) Exposing plasmids as the Achilles' heel of drug-resistant bacteria. Curr Opin Chem Biol 12: 389-399.
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 389-399
    • Williams, J.J.1    Hergenrother, P.J.2
  • 35
    • 77956276376 scopus 로고    scopus 로고
    • Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules
    • Yang M, Gao C, Wang Y, Zhang H & He ZG (2010) Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules. PLoS One 5: e10672.
    • (2010) PLoS One , vol.5
    • Yang, M.1    Gao, C.2    Wang, Y.3    Zhang, H.4    He, Z.G.5
  • 36
    • 78751537637 scopus 로고    scopus 로고
    • The three Vibrio cholerae chromosome II-encoded ParE toxins degrade chromosome I following loss of chromosome II
    • Yuan J, Yamaichi Y & Waldor MK (2011) The three Vibrio cholerae chromosome II-encoded ParE toxins degrade chromosome I following loss of chromosome II. J Bacteriol 193: 611-619.
    • (2011) J Bacteriol , vol.193 , pp. 611-619
    • Yuan, J.1    Yamaichi, Y.2    Waldor, M.K.3
  • 37
    • 65549106453 scopus 로고    scopus 로고
    • Staphylococcus aureus MazF specifically cleaves a pentad sequence, UACAU, which is unusually abundant in the mRNA for pathogenic adhesive factor SraP
    • Zhu L, Inoue K, Yoshizumi S, Kobayashi H, Zhang Y, Ouyang M, Kato F, Sugai M & Inouye M (2009) Staphylococcus aureus MazF specifically cleaves a pentad sequence, UACAU, which is unusually abundant in the mRNA for pathogenic adhesive factor SraP. J Bacteriol 191: 3248-3255.
    • (2009) J Bacteriol , vol.191 , pp. 3248-3255
    • Zhu, L.1    Inoue, K.2    Yoshizumi, S.3    Kobayashi, H.4    Zhang, Y.5    Ouyang, M.6    Kato, F.7    Sugai, M.8    Inouye, M.9


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