Regional fat deposition and cardiovascular risk in HIV infection: The FRAM study

AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV

Volumn 23, Issue 8, 2011, Pages 929-938

  Lake, Jordan E ^a   Wohl, David ^b   Scherzer, Rebecca ^c,d   Grunfeld, Carl ^c,d   Tien, Phyllis C ^c,d   Sidney, Stephen ^e   Currier, Judith S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e DIVISION OF RESEARCH   (United States)

Author keywords

cardiovascular risk; fat redistribution; HIV; lipoatrophy; visceral fat

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ADULT; ARM; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; FRAMINGHAM RISK SCORE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRAABDOMINAL FAT; ISCHEMIC HEART DISEASE; LEG; LIPID STORAGE; LIPOATROPHY; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SMOKING; SUBCUTANEOUS FAT; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; TRUNK; WHOLE BODY MRI;

ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BODY FAT DISTRIBUTION; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; HIV INFECTIONS; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; INTRA-ABDOMINAL FAT; LEG; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RISK FACTORS; SUBCUTANEOUS FAT; WHOLE BODY IMAGING;

EID: 79960620391     PISSN: 09540121     EISSN: 13600451     Source Type: Journal    
DOI: 10.1080/09540121.2010.543885     Document Type: Article

References (34)

1. Aboud, M., Elgalib, A., Pomeroy, L., Panayiotakopoulos, G., Skopelitis, E., Kulasegaram, R., Peters, B.S. (2010). Cardiovascular risk evaluation and antiretroviral therapy effects in an HIV cohort: Implications for clinical management: The CREATE 1 study. International Journal of Clinical Practice, 64(9), 1252-1259.
2. Anderson, K.M., Wilson, P.W., Odell, P.M., & Kannel, W.B. (1991). An updated coronary risk profile. A statement for health professionals. Circulation, 83(1), 356-362.
3. Bacchetti, P., Cofrancesco, J., Heymsfield, S., Lewis, C.E., Scherzer, R., Shlipak, M., & Tien, P.C. (2006). Fat distribution in women with HIV infection. Journal of Acquired Immune Deficiency Syndromes, 42(5), 562-571. (Pubitemid 44162424)
4. Bacchetti, P., Gripshover, B., Grunfeld, C., Heymsfield, S., McCreath, H., Osmond, D., Tien, P. (2005). Fat distribution in men with HIV infection. Journal of Acquired Immune Deficiency Syndromes, 40(2), 121-131. (Pubitemid 41395709)
5. Currier, J., Scherzer, R., Bacchetti, P., Heymsfield, S., Lee, D., Sidney, S., & Tien, P.C. (2008). Regional adipose tissue and lipid and lipoprotein levels in HIV-infected women. Journal of Acquired Immune Deficiency Syndromes, 48(1), 35-43. (Pubitemid 351600850)
6. Currier, J.S., Taylor, A., Boyd, F., Dezii, C.M., Kawabata, H., Burtcel, B., Hodder, S. (2003). Coronary heart disease in HIV-infected individuals. Journal of Acquired Immune Deficiency Syndromes, 33(4), 506-512. (Pubitemid 36886080)
7. De Socio, G.V., Parruti, G., Quirino, T., Ricci, E., Schillaci, G., Adriani, B., Bonfanti, P. (2008). Identifying HIV patients with an unfavorable cardiovascular risk profile in the clinical practice: Results from the SIMONE study. Journal of Infections, 57(1), 33-40.
8. Dolan, S.E., Hadigan, C., Killilea, K.M., Sullivan, M.P., Hemphill, L., Lees, R.S., Grinspoon, S. (2005). Increased cardiovascular disease risk indices in HIVinfected women. Journal of Acquired Immune Deficiency Syndromes, 39(1), 44-54. (Pubitemid 40617018)
9. El-Sadr, W.M., Mullin, C.M., Carr, A., Gibert, C., Rappoport, C., Visnegarwala, F., Raghavan, S.S. (2005). Effects of HIV disease on lipid, glucose and insulin levels: Results from a large antiretroviral-naive cohort. HIV Medicine, 6(2), 114-121. (Pubitemid 40425975)
10. Friedman, G.D., Cutter, G.R., Donahue, R.P., Hughes, G.H., Hulley, S.B., Jacobs, D.R., Jr., Savage, P.J. (1988). CARDIA: Study design, recruitment, and some characteristics of the examined subjects. Journal of Clinical Epidemiology, 41(11), 1105-1116. (Pubitemid 19039041)
11. Friis-Møller, N., Sabin, C.A., Weber, R., dArminio Monforte, A., El-Sadr, W.M., Reiss, P., Lundgren, J.D. (2003). Combination antiretroviral therapy and the risk of myocardial infarction. New England Journal of Medicine, 349(21), 1993-2003.
12. Friis-Møller, N., Thiebaut, R., Reiss, P., Weber, R., Monforte, A.D., De Wit, S., Law, M.G. (2010). Predicting the risk of cardiovascular disease in HIVinfected patients: The data collection on adverse effects of anti-HIV drugs study. European Journal of Cardiovascular Prevention and Rehabilitation, 17(5), 491-501.
13. Gallagher, D., Belmonte, D., Deurenberg, P., Wang, Z., Krasnow, N., Pi-Sunyer, F.X., & Heymsfield, S.B. (1998). Organ-tissue mass measurement allows modeling of REE and metabolically active tissue mass. American Journal of Physiology, 275(2, Pt. 1), E249-E258.
14. Galli, M., Veglia, F., Angarano, G., Santambrogio, S., Meneghini, E., Gritti, F., Lazzarin, A. (2003). Gender differences in antiretroviral drug-related adipose tissue alterations. Women are at higher risk than men and develop particular lipodystrophy patterns. Journal of Acquired Immune Deficiency Syndromes, 34(1), 58-61. (Pubitemid 37100112)
15. Grunfeld, C., Delaney, J.A., Wanke, C., Currier, J.S., Scherzer, R., Biggs, M.L., Kronmal, R.A. (2009). Preclinical atherosclerosis due to HIV infection: Carotid intima-medial thickness measurements from the FRAM study. AIDS, 23(14), 1841-1849.
16. Grunfeld, C., Kotler, D.P., Hamadeh, R., Tierney, A., Wang, J., & Pierson, R.N. (1989). Hypertriglyceridemia in the acquired immunodeficiency syndrome. American Journal of Medicine, 86(1), 27-31.
17. Grunfeld, C., Pang, M., Doerrler, W., Shigenaga, J.K., Jensen, P., & Feingold, K.R. (1992). Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. Journal of Clinical Endocrinology & Metabolism, 74(5), 1045-1052.
18. Grunfeld, C., Rimland, D., Gibert, C.L., Powderly, W.G., Sidney, S., Shlipak, M.G., Heymsfield, S.B. (2007). Association of upper trunk and visceral adipose tissue volume with insulin resistance in control and HIVinfected subjects in the FRAM study. Journal of Acquired Immune Deficiency Syndromes, 46(3), 283-290. (Pubitemid 350287354)
19. Hadigan, C., Meigs, J.B., Wilson, P.W., DAgostino, R.B., Davis, B., Basgoz, N., Grinspoon, S. (2003). Prediction of coronary heart disease risk in HIV-infected patients with fat redistribution. Clinical Infectious Diseases, 36(7), 909-916. (Pubitemid 36403525)
20. Kaplan, R.C., Kingsley, L.A., Sharrett, A.R., Li, X., Lazar, J., Tien, P.C., Gange, S.J. (2007). Ten-year predicted coronary heart disease risk in HIV-infected men and women. Clinical Infectious Diseases, 45(8), 1074-1081. (Pubitemid 47580361)
21. Kosmiski, L.A., Bacchetti, P., Kotler, D.P., Heymsfield, S.B., Lewis, C.E., Shlipak, M.G., Grunfeld, C. (2008). Relationship of fat distribution with adipokines in human immunodeficiency virus infection. Journal of Clinical Endocrinology & Metabolism, 93(1), 216-224.
22. Kotler, D.P. (2008). HIV and antiretroviral therapy: Lipid abnormalities and associated cardiovascular risk in HIV-infected patients. Journal of Acquired Immune Deficiency Syndromes, 49(Suppl. 2), S79-S85.
23. Lee, G.A., Seneviratne, T., Noor, M.A., Lo, J.C., Schwarz, J.M., Aweeka, F.T., Grunfeld, C. (2004). The metabolic effects of lopinavir/ritonavir in HIV-negative men. AIDS, 18(4), 641-649. (Pubitemid 38393463)
24. Mulligan, K., Parker, R.A., Komarow, L., Grinspoon, S.K., Tebas, P., Robbins, G.K., Dube, M.P. (2006). Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial. Journal of Acquired Immune Deficiency Syndromes, 41(5), 590-597.
25. Nieves, D.J., Cnop, M., Retzlaff, B., Walden, C.E., Brunzell, J.D., Knopp, R.H., Kahn, S.E. (2003). The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to intra-abdominal fat. Diabetes, 52(1), 172-179. (Pubitemid 36042123)
26. Rossi, R., Nuzzo, A., Guaraldi, G., Orlando, G., Squillace, N., Ligabue, G., Modena, M.G. (2009). The role of the Framingham risk score to predict the presence of subclinical coronary atherosclerosis in patients with HIV infection. Journal of Acquired Immune Deficiency Syndromes, 52(2), 303-304.
27. Saint-Marc, T., Partisani, M., Poizot-Martin, I., Rouviere, O., Bruno, F., Avellaneda, R., Touraine, J.L. (2000). Fat distribution evaluated by computed tomography and metabolic abnormalities in patients undergoing antiretroviral therapy: Preliminary results of the LIPOCO study. AIDS, 14(1), 37-49. (Pubitemid 30072076)
28. Snijder, M.B., Visser, M., Dekker, J.M., Goodpaster, B.H., Harris, T.B., Kritchevsky, S.B., Seidell, J.C. (2005). Low subcutaneous thigh fat is a risk factor for unfavourable glucose and lipid levels, independently of high abdominal fat. The Health ABC Study. Diabetologia, 48(2), 301-308. (Pubitemid 40543303)
29. Stein, J.H., Klein, M.A., Bellehumeur, J.L., McBride, P.E., Wiebe, D.A., Otvos, J.D., & Sosman, J.M. (2001). Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction. Circulation, 104(3), 257-262. (Pubitemid 32666944)
30. Tien, P.C., Benson, C., Zolopa, A.R., Sidney, S., Osmond, D., & Grunfeld, C. (2006). The study of fat redistribution and metabolic change in HIV infection (FRAM): Methods, design, and sample characteristics. American Journal of Epidemiology, 163(9), 860-869.
31. Tien, P.C., Cole, S.R., Williams, C.M., Li, R., Justman, J.E., Cohen, M.H., Grunfeld, C. (2003). Incidence of lipoatrophy and lipohypertrophy in the womens interagency HIV study. Journal of Acquired Immune Deficiency Syndromes, 34(5), 461-466. (Pubitemid 37500469)
32. Triant, V.A., Lee, H., Hadigan, C., & Grinspoon, S.K. (2007). Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus disease. Journal of Clinical Endocrinology & Metabolism, 92(7), 2506-2512. (Pubitemid 47037350)
33. Wohl, D., Scherzer, R., Heymsfield, S., Simberkoff, M., Sidney, S., Bacchetti, P., & Grunfeld, C. (2008). The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men. Journal of Acquired Immune Deficiency Syndromes, 48(1), 44-52. (Pubitemid 351600858)
34. Yim, J.E., Heshka, S., Albu, J.B., Heymsfield, S., & Gallagher, D. (2008). Femoral-gluteal subcutaneous and intermuscular adipose tissues have independent and opposing relationships with CVD risk. Journal of Applied Physiology, 104(3), 700-707. (Pubitemid 351468798)