-
1
-
-
0028942436
-
Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991
-
Burt VL, et al. (1995) Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991. Hypertension 25:305-313.
-
(1995)
Hypertension
, vol.25
, pp. 305-313
-
-
Burt, V.L.1
-
2
-
-
0034711753
-
Essential hypertension. Part I: Definition and etiology
-
Carretero OA, Oparil S (2000) Essential hypertension. Part I: Definition and etiology. Circulation 101:329-335.
-
(2000)
Circulation
, vol.101
, pp. 329-335
-
-
Carretero, O.A.1
Oparil, S.2
-
3
-
-
0030068024
-
Molecular genetics of human blood pressure variation
-
Lifton RP (1996) Molecular genetics of human blood pressure variation. Science 272:676-680.
-
(1996)
Science
, vol.272
, pp. 676-680
-
-
Lifton, R.P.1
-
4
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
DOI 10.1126/science.1062844
-
Wilson FH, et al. (2001) Human hypertension caused by mutations in WNK kinases. Science 293:1107-1112. (Pubitemid 32758085)
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1107-1112
-
-
Wilson, F.H.1
Disse-Nicodeme, S.2
Choate, K.A.3
Ishikawa, K.4
Nelson-Williams, C.5
Desitter, I.6
Gunel, M.7
Milford, D.V.8
Lipkin, G.W.9
Achard, J.-M.10
Feely, M.P.11
Dussol, B.12
Berland, Y.13
Unwin, R.J.14
Mayan, H.15
Simon, D.B.16
Farfel, Z.17
Jeunemaitre, X.18
Lifton, R.P.19
-
5
-
-
33749118898
-
Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule
-
DOI 10.1038/ng1877, PII NG1877
-
Lalioti MD, et al. (2006) Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nat Genet 38:1124-1132. (Pubitemid 44470357)
-
(2006)
Nature Genetics
, vol.38
, Issue.10
, pp. 1124-1132
-
-
Lalioti, M.D.1
Zhang, J.2
Volkman, H.M.3
Kahle, K.T.4
Hoffmann, K.E.5
Toka, H.R.6
Nelson-Williams, C.7
Ellison, D.H.8
Flavell, R.9
Booth, C.J.10
Lu, Y.11
Geller, D.S.12
Lifton, R.P.13
-
6
-
-
34247617951
-
Molecular pathogenesis of pseudohypoaldosteronism type II: Generation and analysis of a Wnk4(D561A/+) knockin mouse model
-
Yang SS, et al. (2007) Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model. Cell Metab 5:331-344.
-
(2007)
Cell Metab
, vol.5
, pp. 331-344
-
-
Yang, S.S.1
-
7
-
-
34147121186
-
Intersectin links WNK kinases to endocytosis of ROMK1
-
DOI 10.1172/JCI30087
-
He G, Wang HR, Huang SK, Huang CL (2007) Intersectin links WNK kinases to endocytosis of ROMK1. J Clin Invest 117:1078-1087. (Pubitemid 46556764)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.4
, pp. 1078-1087
-
-
He, G.1
Wang, H.-R.2
Huang, S.-K.3
Huang, C.-L.4
-
8
-
-
43549123915
-
Molecular physiology of the WNK kinases
-
DOI 10.1146/annurev.physiol.70.113006.100651
-
Kahle KT, Ring AM, Lifton RP (2008) Molecular physiology of the WNK kinases. Annu Rev Physiol 70:329-355. (Pubitemid 351738183)
-
(2008)
Annual Review of Physiology
, vol.70
, pp. 329-355
-
-
Kahle, K.T.1
Ring, A.M.2
Lifton, R.P.3
-
9
-
-
0345659215
-
+ secretion
-
DOI 10.1038/ng1271
-
Kahle KT, et al. (2003) WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion. Nat Genet 35:372-376. (Pubitemid 37486922)
-
(2003)
Nature Genetics
, vol.35
, Issue.4
, pp. 372-376
-
-
Kahle, K.T.1
Wilson, F.H.2
Leng, Q.3
Lalioti, M.D.4
O'Connell, A.D.5
Dong, K.6
Rapson, A.K.7
MacGregor, G.G.8
Giebisch, G.9
Hebert, S.C.10
Lifton, R.P.11
-
10
-
-
0037382813
-
Negative regulators of sodium transport in the kidney: Key factors in understanding salt-sensitive hypertension?
-
Rossier BC (2003) Negative regulators of sodium transport in the kidney: key factors in understanding salt-sensitive hypertension? J Clin Invest 111:947-950.
-
(2003)
J Clin Invest
, vol.111
, pp. 947-950
-
-
Rossier, B.C.1
-
11
-
-
1242319290
-
- flux in extrarenal epithelia
-
DOI 10.1073/pnas.0308434100
-
Kahle KT, et al. (2004) WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. Proc Natl Acad Sci USA 101:2064-2069. (Pubitemid 38229015)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.7
, pp. 2064-2069
-
-
Kahle, K.T.1
Gimenez, I.2
Hassan, H.3
Wilson, F.H.4
Wong, R.D.5
Forbush, B.6
Aronson, P.S.7
Lifton, R.P.8
-
12
-
-
33747624445
-
Transient receptor potential channels in cardiovascular function and disease
-
DOI 10.1161/01.RES.0000233356.10630.8a, PII 0000301220060721000005
-
Inoue R, et al. (2006) Transient receptor potential channels in cardiovascular function and disease. Circ Res 99:119-131. (Pubitemid 44297035)
-
(2006)
Circulation Research
, vol.99
, Issue.2
, pp. 119-131
-
-
Inoue, R.1
Jensen, L.J.2
Shi, J.3
Morita, H.4
Nishida, M.5
Honda, A.6
Ito, Y.7
-
13
-
-
44649128517
-
TRP channel and cardiovascular disease
-
Watanabe H, Murakami M, Ohba T, Takahashi Y, Ito H (2008) TRP channel and cardiovascular disease. Pharmacol Ther 118:337-351.
-
(2008)
Pharmacol Ther
, vol.118
, pp. 337-351
-
-
Watanabe, H.1
Murakami, M.2
Ohba, T.3
Takahashi, Y.4
Ito, H.5
-
14
-
-
18044397693
-
TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteries
-
DOI 10.1152/ajpheart.00861.2004
-
Reading SA, Earley S, Waldron BJ, Welsh DG, Brayden JE (2005) TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteries. Am J Physiol Heart Circ Physiol 288:H2055-H2061. (Pubitemid 40604087)
-
(2005)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.288
, Issue.5
-
-
Reading, S.A.1
Earley, S.2
Waldron, B.J.3
Welsh, D.G.4
Brayden, J.E.5
-
15
-
-
58149393175
-
Increased transient receptor potential canonical type 3 channels in vasculature from hypertensive rats
-
Liu D, et al. (2009) Increased transient receptor potential canonical type 3 channels in vasculature from hypertensive rats. Hypertension 53:70-76.
-
(2009)
Hypertension
, vol.53
, pp. 70-76
-
-
Liu, D.1
-
16
-
-
67649644420
-
Transient receptor potential canonical type 3 channels and blood pressure in humans
-
Thilo F, et al. (2009) Transient receptor potential canonical type 3 channels and blood pressure in humans. J Hypertens 27:1217-1223.
-
(2009)
J Hypertens
, vol.27
, pp. 1217-1223
-
-
Thilo, F.1
-
17
-
-
61349089794
-
Increased TRPC3 expression in vascular endothelium of patients with malignant hypertension
-
Thilo F, Loddenkemper C, Berg E, Zidek W, TepelM (2009) Increased TRPC3 expression in vascular endothelium of patients with malignant hypertension. Mod Pathol 22:426-430.
-
(2009)
Mod Pathol
, vol.22
, pp. 426-430
-
-
Thilo, F.1
Loddenkemper, C.2
Berg, E.3
Zidek, W.4
Tepel, M.5
-
18
-
-
4644290321
-
Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension
-
DOI 10.1073/pnas.0405908101
-
Yu Y, et al. (2004) Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Proc Natl Acad Sci USA 101:13861-13866. (Pubitemid 39298498)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.38
, pp. 13861-13866
-
-
Yu, Y.1
Fantozzi, I.2
Remillard, C.V.3
Landsberg, J.W.4
Kunichika, N.5
Platoshyn, O.6
Tigno, D.D.7
Thistlethwaite, P.A.8
Rubin, L.J.9
Yuan, J.X.-J.10
-
19
-
-
0033590450
-
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
-
Hofmann T, et al. (1999) Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397:259-263.
-
(1999)
Nature
, vol.397
, pp. 259-263
-
-
Hofmann, T.1
-
20
-
-
0025080602
-
Structure and function of small arteries
-
Mulvany MJ, Aalkjaer C (1990) Structure and function of small arteries. Physiol Rev 70:921-961. (Pubitemid 20364819)
-
(1990)
Physiological Reviews
, vol.70
, Issue.4
, pp. 921-961
-
-
Mulvany, M.J.1
Aalkjaer, C.2
-
21
-
-
0025924287
-
Increased Ca2+ signaling after alpha-adrenoceptor activation in vascular hypertrophy
-
Papageorgiou P, Morgan KG (1991) Increased Ca2+ signaling after alpha-adrenoceptor activation in vascular hypertrophy. Circ Res 68:1080-1084.
-
(1991)
Circ Res
, vol.68
, pp. 1080-1084
-
-
Papageorgiou, P.1
Morgan, K.G.2
-
22
-
-
51749116707
-
Roles of TRP channels in the development of cardiac hypertrophy
-
Nishida M, Kurose H (2008) Roles of TRP channels in the development of cardiac hypertrophy. Naunyn Schmiedebergs Arch Pharmacol 378:395-406.
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.378
, pp. 395-406
-
-
Nishida, M.1
Kurose, H.2
-
23
-
-
33751104984
-
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy
-
DOI 10.1038/sj.emboj.7601417, PII 7601417
-
Onohara N, et al. (2006) TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. EMBO J 25:5305-5316. (Pubitemid 44764140)
-
(2006)
EMBO Journal
, vol.25
, Issue.22
, pp. 5305-5316
-
-
Onohara, N.1
Nishida, M.2
Inoue, R.3
Kobayashi, H.4
Sumimoto, H.5
Sato, Y.6
Mori, Y.7
Nagao, T.8
Kurose, H.9
-
24
-
-
0029084080
-
Reversible permeabilization. A novel technique for the intracellular introduction of antisense oligodeoxynucleotides into intact smooth muscle
-
Lesh RE, Somlyo AP, Owens GK, Somlyo AV (1995) Reversible permeabilization. A novel technique for the intracellular introduction of antisense oligodeoxynucleotides into intact smooth muscle. Circ Res 77:220-230.
-
(1995)
Circ Res
, vol.77
, pp. 220-230
-
-
Lesh, R.E.1
Somlyo, A.P.2
Owens, G.K.3
Somlyo, A.V.4
-
25
-
-
0037477379
-
3 receptor-independent process
-
DOI 10.1074/jbc.M303890200
-
Wedel BJ, Vazquez G, McKay RR, St J Bird G, Putney JW, Jr. (2003) A calmodulin/ inositol 1,4,5-trisphosphate (IP3) receptor-binding region targets TRPC3 to the plasma membrane in a calmodulin/IP3 receptor-independent process. J Biol Chem 278:25758-25765. (Pubitemid 36835333)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.28
, pp. 25758-25765
-
-
Wedel, B.J.1
Vazquez, G.2
McKay, R.R.3
Bird, G.St.J.4
Putney Jr., J.W.5
-
26
-
-
0035936780
-
Molecular mechanisms of human hypertension
-
DOI 10.1016/S0092-8674(01)00241-0
-
Lifton RP, Gharavi AG, Geller DS (2001) Molecular mechanisms of human hypertension. Cell 104:545-556. (Pubitemid 32201949)
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 545-556
-
-
Lifton, R.P.1
Gharavi, A.G.2
Geller, D.S.3
-
28
-
-
56349151939
-
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
-
Richardson C, Alessi DR (2008) The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway. J Cell Sci 121:3293-3304.
-
(2008)
J Cell Sci
, vol.121
, pp. 3293-3304
-
-
Richardson, C.1
Alessi, D.R.2
-
29
-
-
36048938340
-
The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex
-
DOI 10.1172/JCI32033
-
Yang CL, Zhu X, Ellison DH (2007) The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex. J Clin Invest 117:3403-3411. (Pubitemid 350096996)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3403-3411
-
-
Yang, C.-L.1
Zhu, X.2
Ellison, D.H.3
-
30
-
-
77950280626
-
Mechanisms for hypercalciuria in pseudohypoaldosteronism type II-causing WNK4 knock-in mice
-
Yang SS, et al. (2010) Mechanisms for hypercalciuria in pseudohypoaldosteronism type II-causing WNK4 knock-in mice. Endocrinology 151:1829-1836.
-
(2010)
Endocrinology
, vol.151
, pp. 1829-1836
-
-
Yang, S.S.1
-
32
-
-
0037382807
-
WNK kinases regulate thiazide-sensitive Na-Cl cotransport
-
DOI 10.1172/JCI200317443
-
Yang CL, Angell J, Mitchell R, Ellison DH (2003) WNK kinases regulate thiazide-sensitive Na-Cl cotransport. J Clin Invest 111:1039-1045. (Pubitemid 36397480)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.7
, pp. 1039-1045
-
-
Yang, C.-L.1
Angell, J.2
Mitchell, R.3
Ellison, D.H.4
-
33
-
-
18244373189
-
Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport
-
DOI 10.1172/JCI200522452
-
Yang CL, Zhu X, Wang Z, Subramanya AR, Ellison DH (2005) Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport. J Clin Invest 115:1379-1387. (Pubitemid 40629058)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1379-1387
-
-
Yang, C.-L.1
Zhu, X.2
Wang, Z.3
Subramanya, A.R.4
Ellison, D.H.5
-
34
-
-
33748136477
-
STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels
-
Huang GN, et al. (2006) STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol 8:1003-1010.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1003-1010
-
-
Huang, G.N.1
-
35
-
-
33646698386
-
V1.3 neuronal L-type calcium channels: Differential targeting and signaling to pCREB
-
DOI 10.1111/j.1460-9568.2006.04734.x
-
Zhang H, et al. (2006) Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB. Eur J Neurosci 23:2297-2310. (Pubitemid 43742862)
-
(2006)
European Journal of Neuroscience
, vol.23
, Issue.9
, pp. 2297-2310
-
-
Zhang, H.1
Fu, Y.2
Altier, C.3
Platzer, J.4
Surmeier, D.J.5
Bezprozvanny, I.6
|