메뉴 건너뛰기




Volumn 78, Issue 3, 2011, Pages 320-325

Liver-specific gene therapy of hepatocellular carcinoma by targeting human telomerase reverse transcriptase with pegylated immuno-lipopolyplexes

Author keywords

Apolipoprotein A I promoter; Hepatocellular carcinoma; hTERT; Pegylated immuno lipopolyplexes; RNA interference

Indexed keywords

APOLIPOPROTEIN A1; GREEN FLUORESCENT PROTEIN; LIPOPLEX; NUCLEOTIDYLTRANSFERASE INHIBITOR; PLASMID VECTOR; SHORT HAIRPIN RNA; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 79960581539     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.12.036     Document Type: Article
Times cited : (8)

References (26)
  • 2
    • 20344366296 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Molecular pathways and new therapeutic targets
    • DOI 10.1055/s-2005-871200
    • L.R. Roberts, and G.J. Gores Hepatocellular carcinoma: molecular pathways and new therapeutic targets Semin. Liver Dis. 12 2005 212 225 (Pubitemid 40781073)
    • (2005) Seminars in Liver Disease , vol.25 , Issue.2 , pp. 212-225
    • Roberts, L.R.1    Gores, G.J.2
  • 3
    • 0028332826 scopus 로고
    • Treatment of hepatocellular carcinoma: Too many options?
    • A.P. Venook Treatment of hepatocellular carcinoma: too many options? J. Clin. Oncol. 12 1994 1323 1334 (Pubitemid 24173950)
    • (1994) Journal of Clinical Oncology , vol.12 , Issue.6 , pp. 1323-1334
    • Venook, A.P.1
  • 5
    • 0033033694 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase mRNA expression and telomerase activity in hepatocellular carcinoma
    • DOI 10.1007/s005350050220
    • K. Nagao, M. Tomimatsu, H. Endo, H. Hisatomi, and K. Hikiji Telomerase reverse transcriptase mRNA expression and telomerase activity in hepatocellular carcinoma J. Gastroenterol. 34 1999 83 87 (Pubitemid 29112340)
    • (1999) Journal of Gastroenterology , vol.34 , Issue.1 , pp. 83-87
    • Nagao, K.1    Tomimatsu, M.2    Endo, H.3    Hisatomi, H.4    Hikiji, K.5
  • 7
    • 0037171586 scopus 로고    scopus 로고
    • Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors
    • DOI 10.1016/S0304-3835(01)00838-2, PII S0304383501008382
    • M. Akiyama, O. Yamada, N. Kanda, S. Akita, T. Kawano, T. Ohno, H. Mizoguchi, Y. Eto, K.C. Anderson, and H. Yamada Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors Cancer Lett. 178 2002 187 197 (Pubitemid 34178544)
    • (2002) Cancer Letters , vol.178 , Issue.2 , pp. 187-197
    • Akiyama, M.1    Yamada, O.2    Kanda, N.3    Akita, S.4    Kawano, T.5    Ohno, T.6    Mizoguchi, H.7    Eto, Y.8    Anderson, K.C.9    Yamada, H.10
  • 8
  • 9
    • 4344683923 scopus 로고    scopus 로고
    • Telomeres and telomerase: New targets for the treatment of liver cirrhosis and hepatocellular carcinoma
    • DOI 10.1016/j.jhep.2004.06.010, PII S0168827804002624
    • A. Lechel, M.P. Manns, and K.L. Rudolph Telomeres and telomerase: new targets for the treatment of liver cirrhosis and hepatocellular carcinoma J. Hepatol. 41 2004 491 497 (Pubitemid 39158760)
    • (2004) Journal of Hepatology , vol.41 , Issue.3 , pp. 491-497
    • Lechel, A.1    Manns, M.P.2    Rudolph, K.L.3
  • 10
    • 77950843538 scopus 로고    scopus 로고
    • The dicey role of Dicer: Implications for RNAi therapy
    • W.M. Merritt, M. Bar-Eli, and A.K. Sood The dicey role of Dicer: implications for RNAi therapy Cancer Res. 70 2010 2571 2574
    • (2010) Cancer Res. , vol.70 , pp. 2571-2574
    • Merritt, W.M.1    Bar-Eli, M.2    Sood, A.K.3
  • 11
    • 0036362266 scopus 로고    scopus 로고
    • Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
    • DOI 10.1046/j.1432-0436.2002.690412.x
    • N.R. Forsyth, W.E. Wright, and J.W. Shay Telomerase and differentiation in multicelluar organisms: turn it off, turn it on, and turn it off again Differentiation 69 2002 188 197 (Pubitemid 41701542)
    • (2002) Differentiation , vol.69 , Issue.4-5 , pp. 188-197
    • Forsyth, N.R.1    Wright, W.E.2    Shay, J.W.3
  • 12
    • 0032903984 scopus 로고    scopus 로고
    • Telomere shortening, telomerase expression, and chromosome instability in rat hepatic epithelial stem-like cells
    • DOI 10.1002/(SICI)1098-2744(199903)24:3<209::AID-MC7>3.0.CO;2-F
    • V.M. Golubovskaya, L.V. Filatov, C.I. Behe, S.C. Presnell, M.J. Hooth, G.J. Smith, and W.K. Kaufmann Telomere shortening, telomerase expression, and chromosome instability in rat hepatic epithelial stem-like cells Mol. Carcinog. 24 1999 209 217 (Pubitemid 29169861)
    • (1999) Molecular Carcinogenesis , vol.24 , Issue.3 , pp. 209-217
    • Golubovskaya, V.M.1    Filatov, L.V.2    Behe, C.I.3    Presnell, S.C.4    Hooth, M.J.5    Smith, G.J.6    Kaufmann, W.K.7
  • 13
    • 0036107320 scopus 로고    scopus 로고
    • Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers
    • DOI 10.1046/j.0106-9543.2001.01594.x
    • V. Kotoula, P. Hytiroglou, A. Pyrpasopoulou, R. Saxena, S.N. Thung, and C.S. Papadimitriou Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers Liver 22 2002 57 69 (Pubitemid 34552526)
    • (2002) Liver , vol.22 , Issue.1 , pp. 57-69
    • Kotoula, V.1    Hytiroglou, P.2    Pyrpasopoulou, A.3    Saxena, R.4    Thung, S.N.5    Papadimitriou, C.S.6
  • 14
    • 77956231793 scopus 로고    scopus 로고
    • Liver-specific expression of an exogenous gene controlled by human apolipoprotein A-I promoter
    • Y. Hu, X. Ren, H. Wang, Y. Ma, L. Wang, Y. Shen, K. Oka, Z. Zhang, and Y. Zhang Liver-specific expression of an exogenous gene controlled by human apolipoprotein A-I promoter Int. J. Pharm. 398 2010 161 164
    • (2010) Int. J. Pharm. , vol.398 , pp. 161-164
    • Hu, Y.1    Ren, X.2    Wang, H.3    Ma, Y.4    Wang, L.5    Shen, Y.6    Oka, K.7    Zhang, Z.8    Zhang, Y.9
  • 15
    • 77953808719 scopus 로고    scopus 로고
    • Pegylated immuno-lipopolyplexes: A novel non-viral gene delivery system for liver cancer therapy
    • Y. Hu, K. Li, L. Wang, S. Yin, Z. Zhang, and Y. Zhang Pegylated immuno-lipopolyplexes: a novel non-viral gene delivery system for liver cancer therapy J. Control. Release 144 2010 75 81
    • (2010) J. Control. Release , vol.144 , pp. 75-81
    • Hu, Y.1    Li, K.2    Wang, L.3    Yin, S.4    Zhang, Z.5    Zhang, Y.6
  • 16
    • 19444381236 scopus 로고    scopus 로고
    • Delivery of β-galactosidase to mouse brain via the blood-brain barrier transferrin receptor
    • DOI 10.1124/jpet.104.082974
    • Y. Zhang, and W.M. Pardridge Delivery of β-galactosidase to mouse brain via the blood-brain barrier transferring receptor J. Pharmacol. Exp. Ther. 313 2005 1075 1081 (Pubitemid 40727011)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.313 , Issue.3 , pp. 1075-1081
    • Zhang, Y.1    Pardridge, W.M.2
  • 17
    • 32444445166 scopus 로고    scopus 로고
    • RNAi-hTERT inhibition hepatocellular carcinoma cell proliferation via decreasing telomerase activity
    • DOI 10.1016/j.jss.2005.09.017, PII S0022480405005007
    • P.H. Zhang, L. Zou, and Z.G. Tu RNAi-hTERT inhibition hepatocellular carcinoma cell proliferation via decreasing telomerase activity J. Surg. Res. 131 2006 143 149 (Pubitemid 43227598)
    • (2006) Journal of Surgical Research , vol.131 , Issue.1 , pp. 143-149
    • Zhang, P.-H.1    Zou, L.2    Tu, Z.-G.3
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • -δδCT method
    • DOI 10.1006/meth.2001.1262
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C (T)) method Methods 25 2001 402 408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 0033957897 scopus 로고    scopus 로고
    • Telomeres, telomerase, and myc. An update
    • DOI 10.1016/S1383-5742(99)00091-5, PII S1383574299000915
    • C. Cerni Telomeres, telomerase, and myc. An update Mutat. Res. 462 2000 31 47 (Pubitemid 30060329)
    • (2000) Mutation Research - Reviews in Mutation Research , vol.462 , Issue.1 , pp. 31-47
    • Cerni, C.1
  • 20
    • 20444408041 scopus 로고    scopus 로고
    • Inhibition of tumor growth and metastasis with antisense oligonucleotides (Cantide) targeting hTERT in an in situ human hepatocellular carcinoma model
    • DOI 10.1111/j.1745-7254.2005.00762.x
    • R.X. Lin, C.W. Tuo, Q.J. Lu, W. Zhang, and S.Q. Wang Inhibition of tumor growth and metastasis with antisense oligonucleotides (Cantide) targeting hTERT in an in situ human hepatocellular carcinoma model Acta Pharmacol. Sin. 26 2005 762 768 (Pubitemid 40806567)
    • (2005) Acta Pharmacologica Sinica , vol.26 , Issue.6 , pp. 762-768
    • Lin, R.-X.1    Tuo, C.-W.2    Lu, Q.-J.3    Zhang, W.4    Wang, S.-Q.5
  • 21
    • 0032732516 scopus 로고    scopus 로고
    • LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth
    • DOI 10.1038/sj.gt.3301026
    • M. Whitemore, S. Li, and L. Huang LPD lipopolyplex inhibits a potent cytokine response and inhibits tumor growth Gene Ther. 6 1999 1867 1875 (Pubitemid 29531282)
    • (1999) Gene Therapy , vol.6 , Issue.11 , pp. 1867-1875
    • Whitmore, M.1    Li, S.2    Huang, L.3
  • 25
    • 0026295038 scopus 로고
    • Mechanism and clinical significance of soluble hepatic cell-surface receptors
    • Y. Kohgo, H. Kondo, Y. Mogi, and Y. Niitsu Mechanism and clinical significance of soluble hepatic cell-surface receptors Targeted Diagn. Ther. 4 1991 305 319
    • (1991) Targeted Diagn. Ther. , vol.4 , pp. 305-319
    • Kohgo, Y.1    Kondo, H.2    Mogi, Y.3    Niitsu, Y.4
  • 26
    • 0032836395 scopus 로고    scopus 로고
    • The asialoglycoprotein receptor in human hepatocellular carcinomas: Its expression on proliferating cells
    • DOI 10.1038/sj.bjc.6690708
    • D. Trere, L. Fiume, L.B. De Giorgi, G. Di Stefano, M. Migaldi, and M. Derenzini The asialoglycoprotein receptor in human hepatocellular carcinomas: its expression on proliferating cells Br. J. Cancer 81 1999 404 408 (Pubitemid 29458792)
    • (1999) British Journal of Cancer , vol.81 , Issue.3 , pp. 404-408
    • Trere, D.1    Fiume, L.2    De Giorgi, L.B.3    Di Stefano, G.4    Migaldi, M.5    Derenzini, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.