Glutamine stimulates the gene expression and processing of sterol regulatory element binding proteins, thereby increasing the expression of their target genes

FEBS Journal

Volumn 278, Issue 15, 2011, Pages 2739-2750

  Inoue, Jun ^a   Ito, Yuka ^a   Shimada, Satoko ^a   Satoh, Shin Ich ^a   Sasaki, Takashi ^a   Hashidume, Tsutomu ^a   Kamoshida, Yuki ^a   Shimizu, Makoto ^a   Sato, Ryuichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

glutamine; processing; Sp1; SREBP; transcriptional regulation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CELL PROTEIN; GLUTAMINE; LIPID; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROL REGULATORY ELEMENT BINDING PROTEIN CLEAVAGE ACTIVATING PROTEIN; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

CELL STIMULATION; CELL STRAIN HEK293; CELL STRAIN HEPG2; COMPLEX FORMATION; CONTROLLED STUDY; CULTURE MEDIUM; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE TARGETING; GOLGI COMPLEX; HOMEOSTASIS; HUMAN; HUMAN CELL; LIPID METABOLISM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROCESSING; PROTEIN TRANSPORT; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ENDOPLASMIC RETICULUM; GENE EXPRESSION; GLUTAMINE; GOLGI APPARATUS; HEP G2 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROL REGULATORY ELEMENT BINDING PROTEINS;

EID: 79960576405     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08204.x     Document Type: Review

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