Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures

Journal of Neuroinflammation

Volumn 8, Issue , 2011, Pages

  Spradling, Kimberly D ^a   Lumley, Lucille A ^a   Robison, Christopher L ^a   Meyerhoff, James L ^b   Dillman III, James F ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b US Army Center for Environmental Health Research   (United States)

Author keywords

Chemical Warfare; Cytokine; Microarray; Nerve Agent; Neuroinflammation; Organophosphate; Piriform Cortex; Sarin; Seizure; Transcriptomics

Indexed keywords

ATROPINE; CHOLINESTERASE INHIBITOR; DIAZEPAM; INTERLEUKIN 10; INTERLEUKIN 6; ORGANOPHOSPHATE; PRALIDOXIME CHLORIDE; SARIN; ANTICONVULSIVE AGENT; CHOLINESTERASE REACTIVATOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PRALIDOXIME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCOTONIN RELATED POLYPEPTIDE ALPHA GENE; CASP8 AND FADD LIKE APOPTOSIS REGULATOR GENE; CD44 GENE; CD63 GENE; CHEMOKINE LIGAND 3 GENE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG TARGETING; EMERIN GENE; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENE STRUCTURE; GLYCOPROTEIN NMB GENE; GTP BINDING GENE; HEME OXYGENASE 1 GENE; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 3 GENE; INTERLEUKIN 1 RECEPTOR TYPE II GENE; INTERLEUKIN 6 GENE; LAMIN A GENE; LD 50; LONG TERM EXPOSURE; MALE; MATRIX METALLOPEPTIDASE 9 GENE; MICROARRAY ANALYSIS; NERVE DEGENERATION; NERVE INJURY; NEUROPEPTIDE Y GENE; NONHUMAN; PODOPLANIN GENE; PYRIFORM CORTEX; RAT; RNA PROCESSING; SEIZURE; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; TUBULIN BETA 6 GENE; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 6 GENE; ANIMAL; BRAIN; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETIC TRANSCRIPTION; HISTOLOGY; HUMAN; PHYSIOLOGY; PRINCIPAL COMPONENT ANALYSIS; SPRAGUE DAWLEY RAT;

ANIMALS; ANTICONVULSANTS; ATROPINE; BRAIN; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; DIAZEPAM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HUMANS; MALE; MICROARRAY ANALYSIS; MUSCARINIC ANTAGONISTS; PRALIDOXIME COMPOUNDS; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; SARIN; SEIZURES; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 79960565709     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-83     Document Type: Article

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