Photodynamic effects of pterin on HeLa cells

Photochemistry and Photobiology

Volumn 87, Issue 4, 2011, Pages 862-866

  Paula Denofrio, M ^a   Lorente, Carolina ^a   Breitenbach, Thomas ^b   Hatz, Sonja ^b   Cabrerizo, Franco M ^c   Thomas, Andrés H ^a   Ogilby, Peter R ^b  

^a INSTITUTO DE INVESTIGACIONES FISICOQUÍMICAS TEÓRICAS Y APLICADAS INIFTA   (Argentina)

^b AARHUS UNIVERSITY   (Denmark)

^c INSTITUTO DE INVESTIGACIONES BIOTECNOLÓGICAS   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; PHOTOSENSITIZING AGENT; PTERIN DERIVATIVE; RHODAMINE 123; TRYPAN BLUE;

ARTICLE; CELL COUNT; CELL DEATH; CHEMISTRY; DRUG EFFECT; FEMALE; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; METABOLISM; METHODOLOGY; MITOCHONDRION; PATHOLOGY; PHOTOCHEMOTHERAPY; RADIATION EXPOSURE; SYNTHESIS; ULTRAVIOLET RADIATION; UTERINE CERVIX TUMOR;

AMINES; CELL COUNT; CELL DEATH; FEMALE; HELA CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PTERINS; RHODAMINE 123; TRYPAN BLUE; ULTRAVIOLET RAYS; UTERINE CERVICAL NEOPLASMS;

EID: 79960564837     PISSN: 00318655     EISSN: 17511097     Source Type: Journal    
DOI: 10.1111/j.1751-1097.2011.00922.x     Document Type: Article

References (34)

1. Nichol, C. A., G. K. Smith, and, D. S. Duch, (1985) Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin. Annu. Rev. Biochem. 54, 729-764. (Pubitemid 15073663)
2. Blakley, R. L., (1969) The Biochemistry of Folic Acid and Related Pteridines. North-Holland Publishing Co., Amsterdam.
3. Hevel, J. M., and, M. A. Marletta, (1992) Macrophage nitric oxide synthase: Relationship between enzyme-bound tetrahydrobiopterin and synthase activity. Biochemistry 31, 7160-7165.
4. Fuchs, D., A. Hausen, G. Reibnegger, E. R. Werner, M. P. Dierich, and, H. Wachter, (1988) Neopterin as marker for activated cell-mediated immunity: Application in HIV infection. Immunol. Today 9, 150-155.
5. Lorente, C., and, A. H. Thomas, (2006) Photophysics and photochemistry of pterins in aqueous solution. Acc. Chem. Res. 39, 395-402.
6. Schallreuter, K. U., J. M. Wood, M. R. Pittelkow, M. Gütlich, K. R. Lemke, W. Rödl, N. N. Swanson, K. Hitzemann, and, I. Ziegler, (1994) Regulation of melanin biosynthesis in the human epidermis by tetrahydrobiopterin. Science, 263, 1444-1446. (Pubitemid 24137834)
7. 2 and pterin-6-carboxylic acid. Biochem. Biophys. Res. Commun. 292, 805-811. (Pubitemid 34687275)
8. van der Leun, J. C., and, F. R. Gruijl de, (2002) Climate change and skin cancer. Photochem. Photobiol. Sci. 1, 324-326.
9. Matsumura, Y., and, H. N. Ananthaswamy, (2004) Toxic effects of ultraviolet radiation on the skin. Toxicol. Appl. Pharmacol. 195, 298-308. (Pubitemid 38338650)
10. Neverov, K. V., E. A. Mironov, T. A. Lyudnikova, A. A. Krasnovsky, and, M. S. Kritsky, (1996) Phosphorescence analysis of the triplet state of pterins in connection with their photoreceptor function in biochemical systems. Biokhimiya (Moscow) 61, 1627-1636.
11. g) production by pterin derivatives in aqueous solutions. Photochem. Photobiol. Sci. 2, 245-250. (Pubitemid 41655727)
12. Briviba, K., L.-O. Klotz, and, H. Sies, (1997) Toxic and signaling effects of photochemically or chemically generated singlet oxygen in biological systems. Biol. Chem. 378, 1259-1265. (Pubitemid 27507541)
13. Kochevar, I. E., M. C. Lynch, S. Zhuang, and, C. R. Lambert, (2000) Singlet oxygen, but not oxidizing radicals, induces apoptosis in HL-60 cells. Photochem. Photobiol. 72, 548-553.
14. Weishaupt, K. R., C. J. Gomer, and, T. J. Dougherty, (1976) Identification of singlet oxygen as the cytotoxic agent in photo-inactivation of a murine tumor. Cancer Res. 36, 2326-2329.
15. Ogilby, P. R., (2010) Singlet oxygen: There is indeed something new under the sun. Chem. Soc. Rev. 39, 3181-3209.
16. Petroselli, G., R. Erra-Balsells, F. M. Cabrerizo, C. Lorente, A. L. Capparelli, A. M. Braun, E. Oliveros, and, A. H. Thomas, (2007) Photosensitization of 2′-deoxyadenosine-5′-monophosphate by pterin. Org. Biomol. Chem. 5, 2792-2799.
17. Petroselli, G., M. L. Dántola, F. M. Cabrerizo, A. L. Capparelli, C. Lorente, E. Oliveros, and, A. H. Thomas, (2008) Oxidation of 2′-deoxyguanosine 5′-monophosphate photoinduced by pterin: Type I versus type II mechanism. J. Am. Chem. Soc. 130, 3001-3011. (Pubitemid 351455971)
18. Ito, K., and, S. Kawanishi, (1997) Photoinduced hydroxylation of deoxyguanosine in DNA by pterins: Sequence specificity and mechanism. Biochemistry 36, 1774-1781. (Pubitemid 27086273)
19. Lorente, C., A. H. Thomas, L. S. Villata, D. Hozbor, A. Lagares, and, A. L. Capparelli, (2000) Título. Pteridines 11, 100-105.
20. Hirakawa, K., H. Suzuki, S. Oikawa, and, S. Kawanishi, (2003) Sequence-specific DNA damage induced by ultraviolet A-irradiated folic acid via its photolysis product. Arch. Biochem. Biophys. 410, 261-268. (Pubitemid 36259826)
21. Offer, T., B. N. Ames, S. W. Bailey, E. A. Sabens, M. Nozawa, and, J. E. Ayling, (2007) 5-Methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA. FASEB J. 21, 2101-2107. (Pubitemid 47026445)
22. Yamada, H., T. Arai, N. Endo, K. Yamashita, M. Nonogawa, K. Makino, K. Fukuda, M. Sasada, and, T. Uchiyama, (2005) Photodynamic effects of a novel pterin derivative on a pancreatic cancer cell line. Biochem. Biophys. Res. Com. 333, 763-767. (Pubitemid 40854225)
23. Miyoshi, T., T. Arai, M. Nonogawa, K. Makino, H. Mori, K. Yamashita, and, M. Sasada, (2008) Anticancer photodynamic and non-photodynamic effects of pterin derivatives on a pancreatic cancer cell line. J. Pharmacol. Sci. 107, 221-225. (Pubitemid 351931023)
24. Hatz, S., J. D. C. Lambert, and, P. R. Ogilby, (2007) Measuring the lifetime of singlet oxygen in a single cell: Addressing the issue of cell viability. Photochem. Photobiol. Sci. 6, 1106-1116. (Pubitemid 47525006)
25. Denofrio, M. P., S. Hatz, C. Lorente, F. M. Cabrerizo, P. R. Ogilby, and, A. H. Thomas, (2009) The photosensitizing activity of lumazine using 2′-deoxyguanosine 5′-monophosphate and HeLa cells as targets. Photochem. Photobiol. Sci. 8, 1539-1549.
26. Skovsen, E., J. W. Snyder, J. D. C. Lambert, and, P. R. Ogilby, (2005) Lifetime and diffusion of singlet oxygen in a cell. J. Phys. Chem. B 109, 8570-8573. (Pubitemid 40750886)
27. Snyder, J. W., E. Skovsen, J. D. C. Lambert, and, P. R. Ogilby, (2005) Subcellular, time-resolved studies of singlet oxygen in single cells. J. Am. Chem. Soc. 127, 14558-14559. (Pubitemid 41510981)
28. Thomas, A. H., C. Lorente, A. L. Capparelli, M. R. Pokhrel, A. M. Braun, and, E. Oliveros, (2002) Fluorescence of pterin, 6-formylpterin, 6-carboxypterin and folic acid in aqueous solutions: pH effects. Photochem. Photobiol. Sci. 1, 421-426. (Pubitemid 37069756)
29. Darzynkiewicz, Z., G. Juan, X. Li, W. Gorczyca, T. Murakami, and, F. Traganos, (1997) Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis). Cytometry 27, 1-20. (Pubitemid 27059777)
30. Johnson, L.V., M. L. Walsh, and, L. B. Chen, (1980) Localization of mitochondria in living cells with rhodamine 123. Proc. Natl Acad. Sci. USA 77, 990-994. (Pubitemid 10105043)
31. Breitenbach, T., M. K. Kuimova, P. Gbur, S. Hatz, N. B. Schack, B. W. Pedersen, J. D. C. Lambert, L. Poulsen, and, P. R. Ogilby, (2009) Photosensitized production of singlet oxygen: Spatially-resolved optical studies in single cells. Photochem. Photobiol. Sci. 8, 442-452.
32. Altman, S. A., L. Randers, and, G. Rao, (1993) Comparison of trypan blue dye exclusion and fluorometric assays for mammalian cell viability determinations. Biotechnol. Prog. 9, 671-674. (Pubitemid 2022153)
33. Cook, J. A., and, J. B. Mitchell, (1989) Viability measurements in mammalian cell systems. Anal. Biochem. 179, 1-7. (Pubitemid 19149618)
34. Breitenbach, T., P. R. Ogilby, and, J. D. C. Lambert, (2010) Effect of intracellular photosensitized singlet oxygen production on the electrophysiological properties of cultured rat hippocampal neurons. Photochem. Photobiol. Sci. 9, 1621-1633.