-
3
-
-
73249142867
-
-
10.1021/jm901390p 1:CAS:528:DC%2BD1MXhsVSgtL%2FE
-
R Pellicciari A Gioiello A Macchiarulo C Thomas E Rosatelli B Natalini R Sardella M Pruzanski A Roda E Pastorini K Schoonjans J Auwerx 2009 J Med Chem 52 7958 7961 10.1021/jm901390p 1:CAS:528:DC%2BD1MXhsVSgtL%2FE
-
(2009)
J Med Chem
, vol.52
, pp. 7958-7961
-
-
Pellicciari, R.1
Gioiello, A.2
MacChiarulo, A.3
Thomas, C.4
Rosatelli, E.5
Natalini, B.6
Sardella, R.7
Pruzanski, M.8
Roda, A.9
Pastorini, E.10
Schoonjans, K.11
Auwerx, J.12
-
4
-
-
41149144697
-
Novel potent and selective bile acid derivatives as TGR5 agonists: Biological screening, structure-activity relationships, and molecular modeling studies
-
DOI 10.1021/jm7015864
-
H Sato A Macchiarulo C Thomas A Gioiello M Une AF Hofmann R Saladin K Schoonjans R Pellicciari J Auwerx 2008 J Med Chem 51 1831 1841 10.1021/jm7015864 1:CAS:528:DC%2BD1cXis1ektLo%3D (Pubitemid 351438866)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.6
, pp. 1831-1841
-
-
Sato, H.1
Macchiarulo, A.2
Thomas, C.3
Gioiello, A.4
Une, M.5
Hofmann, A.F.6
Saladin, R.7
Schoonjans, K.8
Pellicciari, R.9
Auwerx, J.10
-
5
-
-
34548508190
-
Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5
-
DOI 10.1021/jm070633p
-
R Pellicciari H Sato A Gioiello G Costantino A Macchiarulo BM Sadeghpour G Giorgi K Schoonjans J Auwerx 2007 J Med Chem 50 4265 4268 10.1021/jm070633p 1:CAS:528:DC%2BD2sXos1KktL8%3D (Pubitemid 47378826)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.18
, pp. 4265-4268
-
-
Pellicciari, R.1
Sato, H.2
Gioiello, A.3
Costantino, G.4
Macchiarulo, A.5
Sadeghpour, B.M.6
Giorgi, G.7
Schoonjans, K.8
Auwerx, J.9
-
6
-
-
33745852636
-
Back door modulation of the farnesoid X receptor: Design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives
-
DOI 10.1021/jm060294k
-
R Pellicciari A Gioiello G Costantino BM Sadeghpour G Rizzo U Meyer DJ Parks A Entrena-Guadix S Fiorucci 2006 J Med Chem 49 4208 4215 10.1021/jm060294k 1:CAS:528:DC%2BD28XmtVSjtrs%3D (Pubitemid 44036664)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.14
, pp. 4208-4215
-
-
Pellicciari, R.1
Gioiello, A.2
Costantino, G.3
Sadeghpour, B.M.4
Rizzo, G.5
Meyer, U.6
Parks, D.J.7
Entrena-Guadix, A.8
Fiorucci, S.9
-
7
-
-
4143056853
-
Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure - Activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid
-
DOI 10.1021/jm049904b
-
R Pellicciari G Costantino E Camaioni BM Sadeghpour A Entrena-Gaudix TM Willson S Fiorucci C Clerici A Gioiello 2004 J Med Chem 47 4559 4569 10.1021/jm049904b 1:CAS:528:DC%2BD2cXlvVOnt7Y%3D (Pubitemid 39096842)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.18
, pp. 4559-4569
-
-
Pellicciari, R.1
Costantino, G.2
Camaioni, E.3
Sadeghpour, B.M.4
Entrena, A.5
Willson, T.M.6
Fiorucci, S.7
Clerici, C.8
Gioiello, A.9
-
8
-
-
0037101810
-
6α-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity
-
DOI 10.1021/jm025529g
-
R Pellicciari S Fiorucci E Camaioni C Clerici G Costantino PR Maloney A Morelli DJ Parks TM Willson 2002 J Med Chem 45 3569 3572 10.1021/jm025529g 1:CAS:528:DC%2BD38XlsVSgs7s%3D (Pubitemid 34856095)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.17
, pp. 3569-3572
-
-
Pellicciari, R.1
Fiorucci, S.2
Camaioni, E.3
Clerici, C.4
Costantino, G.5
Maloney, P.R.6
Morelli, A.7
Parks, D.J.8
Willson, T.M.9
-
9
-
-
69149083245
-
-
10.1016/j.cmet.2009.08.001 1:CAS:528:DC%2BD1MXhsVChtLnM
-
C Thomas A Gioiello L Noriega A Strehle J Oury G Rizzo A Macchiarulo H Yamamoto C Mataki M Pruzanski R Pellicciari J Auwerx K Schoonjans 2009 Cell Metab 10 167 177 10.1016/j.cmet.2009.08.001 1:CAS:528:DC%2BD1MXhsVChtLnM
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
Strehle, A.4
Oury, J.5
Rizzo, G.6
MacChiarulo, A.7
Yamamoto, H.8
Mataki, C.9
Pruzanski, M.10
Pellicciari, R.11
Auwerx, J.12
Schoonjans, K.13
-
10
-
-
54249119158
-
-
10.1021/ci800196h 1:CAS:528:DC%2BD1cXpslegtbk%3D
-
A Macchiarulo A Gioiello C Thomas A Massarotti R Nuti E Rosatelli P Sabbatini K Schoonjans J Auwerx R Pellicciari 2008 J Chem Inf Model 48 1792 1801 10.1021/ci800196h 1:CAS:528:DC%2BD1cXpslegtbk%3D
-
(2008)
J Chem Inf Model
, vol.48
, pp. 1792-1801
-
-
MacChiarulo, A.1
Gioiello, A.2
Thomas, C.3
Massarotti, A.4
Nuti, R.5
Rosatelli, E.6
Sabbatini, P.7
Schoonjans, K.8
Auwerx, J.9
Pellicciari, R.10
-
11
-
-
50249180215
-
-
10.1007/s00018-008-7568-6 1:CAS:528:DC%2BD1cXhtVansrzL
-
AF Hofmann LR Hagey 2008 Cell Mol Life Sci 65 2461 2483 10.1007/s00018-008-7568-6 1:CAS:528:DC%2BD1cXhtVansrzL
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2461-2483
-
-
Hofmann, A.F.1
Hagey, L.R.2
-
12
-
-
0021146633
-
-
10.1002/hep.1840040824
-
MC Carey 1984 Hepatology 5 138S 150S 10.1002/hep.1840040824
-
(1984)
Hepatology
, vol.5
-
-
Carey, M.C.1
-
13
-
-
0024318186
-
-
1:CAS:528:DyaL1MXkvFeitrw%3D
-
DH Heuman 1989 J Lipid Res 30 719 730 1:CAS:528:DyaL1MXkvFeitrw%3D
-
(1989)
J Lipid Res
, vol.30
, pp. 719-730
-
-
Heuman, D.H.1
-
16
-
-
0022656312
-
Bile acid-induced liver toxicity: Relation to the hydrophobic-hydrophilic balance of bile acids
-
DOI 10.1016/0306-9877(86)90137-4
-
AF Attili M Angelico A Cantafora D Alvaro L Capocaccia 1986 Med Hypotheses 19 57 69 10.1016/0306-9877(86)90137-4 1:CAS:528:DyaL28XlvVymtrg%3D (Pubitemid 16147457)
-
(1986)
Medical Hypotheses
, vol.19
, Issue.1
, pp. 57-69
-
-
Attili, A.F.1
Angelico, M.2
Cantafora, A.3
-
19
-
-
0027402651
-
0) based on the slope and the intercept of the log k' versus organic phase concentration plot
-
DOI 10.1016/0021-9673(93)80506-4
-
K Valkó P Slégel 1993 J Chromatogr 631 49 61 10.1016/0021-9673(93)80506-4 (Pubitemid 23055440)
-
(1993)
Journal of Chromatography
, vol.631
, Issue.1-2
, pp. 49-61
-
-
Valko, K.1
Slegel, P.2
-
22
-
-
2342635206
-
Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution
-
DOI 10.1016/j.chroma.2003.10.084, PII S0021967303019095
-
K Valkó 2004 J Chromatogr A 1037 299 310 10.1016/j.chroma.2003.10. 084 (Pubitemid 38591346)
-
(2004)
Journal of Chromatography A
, vol.1037
, Issue.1-2
, pp. 299-310
-
-
Valko, K.1
-
24
-
-
24944554875
-
Determination of lipophilicity by reversed-phase high-performance liquid chromatography: Influence of 1-octanol in the mobile phase
-
DOI 10.1016/j.chroma.2005.07.029, PII S0021967305014573
-
X Liu H Tanaka A Yamauchi B Testa H Chuman 2005 J Chromatogr A 1091 51 59 10.1016/j.chroma.2005.07.029 1:CAS:528:DC%2BD2MXhtVWgsL7O (Pubitemid 41317565)
-
(2005)
Journal of Chromatography A
, vol.1091
, Issue.1-2
, pp. 51-59
-
-
Liu, X.1
Tanaka, H.2
Yamauchi, A.3
Testa, B.4
Chuman, H.5
-
25
-
-
3042522989
-
w′ hydrophobicity parameter
-
DOI 10.1016/j.chroma.2004.05.039, PII S0021967304007897
-
PA Tate JG Dorsey 2004 J Chromatogr A 1042 37 48 10.1016/j.chroma.2004. 05.039 1:CAS:528:DC%2BD2cXlt1antrY%3D (Pubitemid 38813350)
-
(2004)
Journal of Chromatography A
, vol.1042
, Issue.1-2
, pp. 37-48
-
-
Tate, P.A.1
Dorsey, J.G.2
-
30
-
-
35748956141
-
Determination of the chromatographic hydrophobicity index for ionisable solutes
-
DOI 10.1016/j.chroma.2007.10.012, PII S0021967307017268
-
E Fuguet C Ràfols E Bosch M Rosés 2007 J Chromatogr A 1173 110 119 10.1016/j.chroma.2007.10.012 1:CAS:528:DC%2BD2sXht12nsrzP (Pubitemid 350046583)
-
(2007)
Journal of Chromatography A
, vol.1173
, Issue.1-2
, pp. 110-119
-
-
Fuguet, E.1
Rafols, C.2
Bosch, E.3
Roses, M.4
-
31
-
-
70349845445
-
-
10.1016/j.chroma.2009.09.031 1:CAS:528:DC%2BD1MXht1ylsrvF
-
E Fuguet C Ràfols E Bosch M Rosés 2009 J Chromatog A 1216 7798 7805 10.1016/j.chroma.2009.09.031 1:CAS:528:DC%2BD1MXht1ylsrvF
-
(2009)
J Chromatog A
, vol.1216
, pp. 7798-7805
-
-
Fuguet, E.1
Ràfols, C.2
Bosch, E.3
Rosés, M.4
-
32
-
-
64349124483
-
-
10.1021/jm801291f 1:CAS:528:DC%2BD1MXisFagt7g%3D
-
SC Karcher SA Laufer 2009 J Med Chem 52 1778 1782 10.1021/jm801291f 1:CAS:528:DC%2BD1MXisFagt7g%3D
-
(2009)
J Med Chem
, vol.52
, pp. 1778-1782
-
-
Karcher, S.C.1
Laufer, S.A.2
-
33
-
-
0000334097
-
-
10.1021/ja01168a046 1:CAS:528:DyaG3MXlsFOhtg%3D%3D
-
F Fieser S Rajagopalan 1950 J Am Chem Soc 72 5530 5536 10.1021/ja01168a046 1:CAS:528:DyaG3MXlsFOhtg%3D%3D
-
(1950)
J Am Chem Soc
, vol.72
, pp. 5530-5536
-
-
Fieser, F.1
Rajagopalan, S.2
-
35
-
-
4243940928
-
-
10.1007/BF01243540 1:CAS:528:DyaK38Xks1Orsw%3D%3D
-
R Shaw WH Elliot BG Barisas 1991 Mikrochim Acta 3 137 145 10.1007/BF01243540 1:CAS:528:DyaK38Xks1Orsw%3D%3D
-
(1991)
Mikrochim Acta
, vol.3
, pp. 137-145
-
-
Shaw, R.1
Elliot, W.H.2
Barisas, B.G.3
-
36
-
-
0021216011
-
-
10.1002/hep.1840040813 1:CAS:528:DyaL2MXnvFajsg%3D%3D
-
A Roda A Fini 1984 Hepatology 4 72S 76S 10.1002/hep.1840040813 1:CAS:528:DyaL2MXnvFajsg%3D%3D
-
(1984)
Hepatology
, vol.4
-
-
Roda, A.1
Fini, A.2
-
37
-
-
0031239583
-
The evaporative light scattering detector: Some applications in pharmaceutical analysis
-
DOI 10.1016/S0165-9936(97)00072-1, PII S0165993697000721
-
M Kohler W Haerdi P Christen JL Veuthey 1997 Trends Anal Chem 16 475 484 10.1016/S0165-9936(97)00072-1 1:CAS:528:DyaK2sXmvVGmt7w%3D (Pubitemid 27451971)
-
(1997)
TrAC - Trends in Analytical Chemistry
, vol.16
, Issue.8
, pp. 475-484
-
-
Kohler, M.1
Haerdi, W.2
Christen, P.3
Veuthey, J.-L.4
-
39
-
-
34447639126
-
-
R. Lo Brutto Y. Kazakevich (eds). Wiley Hoboken
-
Lo Brutto R, Kazakevich Y (eds) (2007) HPLC for pharmaceutical scientists. Wiley, Hoboken
-
(2007)
HPLC for Pharmaceutical Scientists
-
-
-
40
-
-
0020559548
-
-
10.1016/S0021-9673(01)87961-9 1:CAS:528:DyaL3sXktlCns74%3D
-
T Braumann G Weber LH Grimme 1983 J Chromatogr 261 329 343 10.1016/S0021-9673(01)87961-9 1:CAS:528:DyaL3sXktlCns74%3D
-
(1983)
J Chromatogr
, vol.261
, pp. 329-343
-
-
Braumann, T.1
Weber, G.2
Grimme, L.H.3
-
41
-
-
50849152679
-
-
10.1016/S0021-9673(00)91610-8 1:CAS:528:DyaL2cXlslarsw%3D%3D
-
M Harnisch HJ Möckel G Schulze 1983 J Chromatogr 282 315 322 10.1016/S0021-9673(00)91610-8 1:CAS:528:DyaL2cXlslarsw%3D%3D
-
(1983)
J Chromatogr
, vol.282
, pp. 315-322
-
-
Harnisch, M.1
Möckel, H.J.2
Schulze, G.3
|