Poly(I:C) synergizes with Th2 cytokines to induce TARC/CCL17 in middle ear fibroblasts established from mucosa of otitis media with effusion

Acta Oto-Laryngologica

Volumn 129, Issue SUPPL. 562, 2009, Pages 57-62

  Nonaka, Manabu ^a   Ogihara, Nozomu ^a   Fukumoto, Akira ^a   Sakanushi, Atsuko ^a   Pawankar, Ruby ^a   Yagi, Toshiaki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Asthma; Eosinophilic inflammation; otitis media; virus infection

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 4; MESSENGER RNA; POLYINOSINIC ACID; THYMUS AND ACTIVATION REGULATED CHEMOKINE; CCL17 PROTEIN, HUMAN; INTERFERON INDUCING AGENT; POLYINOSINIC POLYCYTIDYLIC ACID;

ASTHMA; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; EARDRUM; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; MIDDLE EAR EFFUSION; MIDDLE EAR MUCOSA; OTITIS MEDIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH2 CELL; THYMUS; UPREGULATION; ARTICLE; CELL CULTURE; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; METABOLISM; MIDDLE EAR; MUCOSA; PATHOLOGY; POLYMERASE CHAIN REACTION; SECRETORY OTITIS MEDIA;

CELLS, CULTURED; CHEMOKINE CCL17; EAR, MIDDLE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; GENE EXPRESSION; HUMANS; INTERFERON INDUCERS; INTERLEUKIN-13; INTERLEUKIN-4; MUCOUS MEMBRANE; OTITIS MEDIA WITH EFFUSION; POLY I-C; POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 79960526313     PISSN: 00016489     EISSN: 16512553     Source Type: Journal    
DOI: 10.1080/00016480902911995     Document Type: Conference Paper

References (24)

1. Chantzi FM, Papadopoulos NG, Bairamis T, Tsiakou M, Bournousouzis N, Constantopoulos AG, et al. Human rhinoviruses in otitis media with effusion. Pediatr Allergy Immunol 2006;17:514-8. (Pubitemid 44511085)
2. Hurst DS, Venge P. The presence of eosinophil cationic protein in middle ear effusion. Otolaryngol Head Neck Surg 1993;108:711-22. (Pubitemid 23199392)
3. Iino Y, Nagamine H, Yabe T, Matsutani S. Eosinophils are activated in middle ear mucosa and middle ear effusion of patients with intractable otitis media associated with bronchial asthma. Clin Exp Allergy 2001;31:1135-43. (Pubitemid 32862845)
4. Nagamine H, Iino Y, Kojima C, Miyazawa T, Iida T. Clinical characteristics of so-called eosinophilic otitis media. Auris Nasus Larynx 2002;29:19-28. (Pubitemid 34076549)
5. Sobol SE, Taha R, Schloss MD, Mazer BD, Manoukian JJ, Tewfik TL, et al. TH2 cytokine expression in atopic children with otitis media with effusion. J Allergy Clin Immunol 2002;110:125-30. (Pubitemid 36132738)
6. Nonaka M, Fukumoto A, Ozu C, Mokuno E, Baba S, Pawankar R, et al. IL-5 and eotaxin levels in middle ear effusion and blood from asthmatics with otitis media with effusion. Acta Otolaryngol 2003;123:383-7. (Pubitemid 36520967)
7. Imai T, Baba M, Nishimura M, Kakizaki M, Takagi S, Yoshie O. The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J Biol Chem 1997;272:15036-42. (Pubitemid 27251781)
8. Fukuda K, Fujitsu Y, Seki K, Kumagai N, Nishida T. Differential expression of thymus-and activation-regulated chemokine (CCL17) and macrophage-derived chemokine (CCL22) by human fibroblasts from cornea, skin, and lung. J Allergy Clin Immunol 2003;111:520-6. (Pubitemid 36337872)
9. Vancheri C, Ohtoshi T, Cox G, Xaubet A, Abrams JS, Gauldie J, et al. Neutrophilic differentiation induced by human upper airway fibroblast-derived granulocyte/macrophage colony-stimulating factor (GM-CSF). Am J Respir Cell Mol Biol 1991;4:11-7.
10. Flolkerts G, Busse W, Nijkamp FP, Sorkness R, Gern JE. Virus-induced airway hyperresponsiveness and asthma. Am J Respir Crit Care Med 1998;157:1708-20.
11. Wright ED, Hurst D, Miotto D, Giguere C, Hamid Q. Increased expression of major basic protein (MBP) and interleukin-5 (IL-5) in middle ear biopsy specimens from atopic patients with persistent otitis media with effusion. Otolaryngol Head Neck Surg 2000;123:533-8.
12. Janssens S, Beyaert R. Role of Toll-like receptors in pathogen recognition. Clin Microbiol Rev 2003;16:637-46. (Pubitemid 37296552)
13. Sen GC. Viruses and interferons. Annu Rev Microbiol 2001;55:255-81. (Pubitemid 32978106)
14. Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001;413:732-8. (Pubitemid 33009951)
15. Xatzipsalti M, Kyrana S, Tsolia M, Psarras S, Bossios A, Laza-Stanca V, et al. Rhinovirus viremia in children with respiratory infections. Am J Respir Crit Care Med 2005;172:1037-40. (Pubitemid 41476543)
16. Papadopoulos NG, Papi A, Psarras S, Johnston SL. Mechanism of rhinovirus-induced asthma. Pediatr Respir Rev 2004;5:255-60.
17. Ghildyal R, Dagher H, Howard D, de Silva D, Li X, Freezer NJ, et al. Rhinovirus infects primary human airway fibroblasts and induces a neutrophil chemokine and a permeability factor. J Med Virol 2005;75:608-15. (Pubitemid 40293530)
18. Elias JA, Wu Y, Zheng T, Panettieri R. Cytokine-and virusstimulated airway smooth muscle cells produce IL-11 and other IL-6-type cytokines. Am J Physiol 1997;273:L648-55. (Pubitemid 27423933)
19. Takahashi N, Yamada T, Narita N, Fujieda S. Doublestranded RNA induces production of RANTES and IL-8 by human nasal fibroblasts. Clin Immunol 2006;118:51-8. (Pubitemid 43012046)
20. Oliver BG, Johnston SL, Baraket M, Burgess JK, King NJ, Roth M, et al. Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection. Respir Res 2006;7:71.
21. Wark PA, Johnston SL, Bucchieri F, Powell R, Puddicombe S, Laza-Stanca V, et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 2005;201:937-47. (Pubitemid 40524463)
22. Xatzipsalti M, Kyrana S, Tsolia M, Psarras S, Bossios A, Laza-Stanca V, et al. Rhinovirus viremia in children with respiratory infections. Am J Respir Crit Care Med 2005;172:1037-40. (Pubitemid 41476543)
23. Kawasaki S, Takizawa H, Yoneyama H, Nakayama T, Fujisawa R, Izumizaki M, et al. Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice. J Immunol 1999;29:2684-94.
24. Fukumoto A, Nonaka M, Ogihara N, Pawankar R. Induction of TARC production by lipopolysaccharide and interleukin-4 in nasal fibroblasts. Int Arch Allergy Immunol 2007;145:291-7.