Eosinophils are activated in middle ear mucosa and middle ear effusion of patients with intractable otitis media associated with bronchial asthma

Clinical and Experimental Allergy

Volumn 31, Issue 7, 2001, Pages 1135-1143

  Iino, Yukiko ^a   Nagamine, H ^a   Yabe, T ^b   Matsutani, S ^c  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b National Hospital Organization   (Japan)

^c Sendai Red Cross Hospital   (Japan)

Author keywords

Bronchial asthma; Chronic otitis media; Eosinophils; IgE mediated allergy; Otitis media with effusion

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY EG1; MONOCLONAL ANTIBODY EG2; TRYPTASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASTHMA; BLOOD STAIN; CELL INFILTRATION; CELL SURFACE; CHRONIC OTITIS MEDIA; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; EOSINOPHIL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY CELL; MALE; MAST CELL; MAST CELL DEGRANULATION; MIDDLE EAR EFFUSION; MIDDLE EAR MUCOSA; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBMUCOSA;

ADULT; ASTHMA; BLOOD PROTEINS; CELL DEGRANULATION; CHRONIC DISEASE; EAR, MIDDLE; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUCOUS MEMBRANE; OTITIS MEDIA WITH EFFUSION; RIBONUCLEASES;

EID: 0034819559     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2001.01134.x     Document Type: Article

References (24)

1. Intractable otitis media in cases with bronchial asthma
2. Allergic otitis media with gelatinous mucoid fluid containing eosinophils
3. Aural manifestations of allergy
4. Intractable otitis media in patients with bronchial asthma (eosinophilic otitis media)
5. The effect of processing on inflammatory markers in induced sputum
6. Nasal polyposis: Epidemiology, pathology, immunology and treatment
7. The presence of atopy does not determine the type of cellular infiltrate in nasal polyps
8. Eosinophilic inflammation in asthma
9. Eosinophilic airway inflammation in nasal polyposis
10. Cytolysis and piecemeal degranulation as distinct modes of activation of airway mucosal eosinophils
11. Neutrophils and eosinphils
12. Eosinophil inflammation of the nasal mucosa in allergic and non-allergic rhinitis measured by eosinophil cationic protein levels in native nasal fluid and serum
13. Eosinophil cationic protein in mucosal biopsies from patients with allergy and otitis media with effusion
14. Association of otitis media with effusion and allergy as demonstrated by intradermal skin testing and eosinophil cationic protein levels in both middle ear effusions and mucosal biopsies
15. Mast cell chymase and tryptase during tissue turnover: Analysis on in vitro mitogenesis of fibroblasts and keratinocytes and alterations in cutaneous scars
16. Tryptase-chymase double-positive human mastcells express the eotaxin receptor CCR3 and are attracted by CCR-binding chemokines
17. Evidence of mast cell activity in the middle ears of children with otitis media with effusion
18. Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry
19. The late phase of the immunoglobulin-E mediated reaction: A link between anaphylaxis and common allergic disease?
20. Immunoglobulin E-dependent inflammation: Eosinophils and other inflammatory cells
21. Assessment of eosinophil and neutrophil participation in atopic dermatitis: Comparison with the IgE-mediated late-phase reaction
22. Intractable otitis media associated with bronchial asthma
23. Identification of T lymphocytes, macrophages and activated eosinophils in the bronchial mucosa in intrinsic asthma: Relationship to symptoms and bronchial responsiveness
24. Local specific IgE production in nasal polyps associated with negative skin tests and serum RAST