The use of real-time cell analyzer technology in drug discovery: Defining optimal cell culture conditions and assay reproducibility with different adherent cellular models

Journal of Biomolecular Screening

Volumn 16, Issue 6, 2011, Pages 575-587

  Atienzar, Franck A ^a   Tilmant, Karen ^a   Gerets, Helga H ^a   Toussaint, Gaelle ^a   Speeckaert, Sebastien ^a   Hanon, Etienne ^a   Depelchin, Olympe ^a   Dhalluin, Stephane ^a  

^a UCB Pharma SA Non Clinical Development   (Belgium)

Author keywords

drug discovery; impedance; label free; quality control; real time cell analyzer (RTCA); reproducibility

Indexed keywords

CARBOPLATIN; CYCLOPHOSPHAMIDE; CYTOCHALASIN B; DASATINIB; DAUNORUBICIN; DIMETHYL SULFOXIDE; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUOROURACIL; IDARUBICIN; IMATINIB; IRINOTECAN; NAVELBINE; SORAFENIB; SUNITINIB; TRITON X 100; VINBLASTINE;

ANALYZER; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL DENSITY; CELL SURFACE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; FIBROBLAST; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IMPEDANCE; LIVER CELL; MOUSE; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REPRODUCIBILITY;

ANIMALS; CELL ADHESION; CELL COUNT; CELL CULTURE TECHNIQUES; CELL LINE; DRUG DISCOVERY; ELECTRIC IMPEDANCE; HEP G2 CELLS; HUMANS; MICE; REPRODUCIBILITY OF RESULTS; SURFACE PROPERTIES;

EID: 79960524769     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111402825     Document Type: Article

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