Topical S-nitrosoglutathione-releasing hydrogel improves healing of rat ischaemic wounds

Journal of Tissue Engineering and Regenerative Medicine

Volumn 5, Issue 8, 2011, Pages 612-619

  Georgii, J L ^a   Amadeu, T P ^a,b   Seabra, A B ^c   de Oliveira, M G ^c   Monte Alto Costa, A ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Ischaemia; Nitric oxide; Skin; Wound healing

Indexed keywords

ANIMALS; NITRIC OXIDE; TISSUE REGENERATION;

BENEFICIAL EFFECTS; CONTROL GROUPS; HIGH RATE; ISCHAEMIA; ISCHEMIC CONDITIONS; NITRIC OXIDE DONOR; S-NITROSOGLUTATHIONE; TOPICAL APPLICATION; WISTAR RAT; WOUND HEALING;

HYDROGELS;

COLLAGEN FIBER; S NITROSOGLUTATHIONE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DRUG EFFECT; EXCISION; HYDROGEL; INCISION; INFLAMMATORY CELL; ISCHEMIA; ISCHEMIC WOUND; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; RAT; SKIN FLAP; SURGICAL WOUND; SUTURING METHOD; WOUND; WOUND CONTRACTION; WOUND HEALING;

EID: 79960474272     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.353     Document Type: Article

References (36)

1. Achuth HN, Moochhala SM, Mahendran R, et al. 2005; Nitrosoglutathione triggers collagen deposition in cutaneous wound repair. Wound Repair Regen 13: 383-389.
2. Amadeu T, Braune A, Mandarim-de-Lacerda C, et al. 2003; Vascularization pattern in hypertrophic scars and keloids: a stereological analysis. Pathol Res Pract 199: 469-473.
3. Amadeu TP, Costa AMA. 2006; Nitric oxide synthesis inhibition alters rat cutaneous wound healing. J Cut Pathol 33: 465-473.
4. Amadeu TP, Seabra AB, De Oliveira MG, et al. 2008; Nitric oxide donor improves healing if applied on inflammatory and proliferative phase. J Surg Res 149: 84-93.
5. Amadeu TP, Seabra AB, Ganzarolli de Oliveira M, et al. 2007; S-nitrosogluthatione accelerates rat cutaneous wound repair. J Eur Acad Dermatol Venereol 21: 629-637.
6. Attinger CE, Hoang H, Steinberg J, et al. 2008; How to make a hospital-based wound center financially viable: the Georgetown University Hospital model. Gynecol Oncol 111: S92-97.
7. Beckert S, Hierlemann H, Müschenborn N, et al. 2005; Experimental ischemic wounds: correlation of cell proliferation and insulin-like growth factor I expression and its modification by different local IGF-I release systems. Wound Repair Regen 13: 278-283.
8. Broughton G, Janis JE, Attinger CE. 2006; Wound healing: an overview. Plast Reconstr Surg 117: 1eS-32eS.
9. Cabral CA, Sampaio FJ, Cardoso LE. 2003; Analysis of the modifications in the composition of bladder glycosaminoglycan and collagen as a consequence of changes in sex hormones associated with puberty or oophorectomy in female rats. J Urol 170: 2512-2516.
10. Cooper DM, Yu EZ, Hennessey P, et al. 1994; Determination of endogenous cytokines in chronic wounds. Ann Surg 219: 688-691.
11. Desmouliere A. 1995; Factors influencing myofibroblast differentiation during wound healing and fibrosis. Cell Biol Int 19: 471-476.
12. Efron DT, Most D, Barbul A. 2000; Role of nitric oxide in wound healing. Curr Opin Clin Nutr Metab Care 3: 197-204.
13. Frank S, Stallmeyer B, Kampfer H, et al. 1999; Nitric oxide triggers enhanced induction of vascular endothelial growth factor expression in cultured keratinocytes (HaCaT) and during cutaneous wound repair. Faseb J 13: 2002-2014.
14. Gould LJ, Leong M, Sonstein J, et al. 2005; Optimization and validation of an ischemic wound model. Wound Repair Regen 13: 576-582.
15. Heck DE, Laskin DL, Gardner CR, et al. 1992; Epidermal growth factor suppresses nitric oxide and hydrogen peroxide production by keratinocytes. Potential role for nitric oxide in the regulation of wound healing. J Biol Chem 267: 21277-21280.
16. Hill YM, Corbett JA, Kwon G, et al. 1996; Nitric oxide regulates interleukin 1 bioactivity released from murine macrophages. J Biol Chem 271: 22672-22678.
17. Izadi K, Ganchi P. 2005; Chronic wounds. Clin Plast Surg 32: 209-222.
18. Kopal C, Deveci M, Öztürk S, et al. 2007; Effects of topical glutathione treatment in rat ischemic wound model. Ann Plast Surg 58: 449-455.
19. Menke NB, Ward KR, Witten TM, et al. 2007; Impaired wound healing. Clin Dermatol 25: 19-25.
20. Mustoe T. 2004; Understanding chronic wounds: a unifying hypothesis on their pathogenesis and implications for therapy. Am J Surg 187: 65S-70S.
21. Poonawala T, Levay-Young BK, Hebbel RP, et al. 2005; Opioids heal ischemic wounds in the rat. Wound Repair Regen 13: 165-174.
22. Quirinia A, Viidik A. 1992; Ischemia in wound healing. Scand J Plast Reconstr Surg Hand Surg 26: 133-139.
23. Rizk M, Witte MB, Barbul A. 2004; Nitric oxide and wound healing. World J Surg 28: 301-306.
24. Rodeberg DA, Chaet MS, Bass RC, et al. 1995; Nitric oxide: an overview. Am J Surg 170: 292-303.
25. Sadoun E, Reed MJ. 2003; Impaired angiogenesis in aging is associated with alterations in vessel density, matrix composition, inflammatory response, and growth factor expression. J Histochem Cytochem 51: 1119-1130.
26. Schwentker A, Vodovotz Y, Weller R, et al. 2002; Nitric oxide and wound repair: role of cytokines? Nitric Oxide 7: 1-10.
27. Seabra AB, Fitzpatrick A, Paul J, et al. 2004; Topically applied S-nitrosothiol-containing hydrogels as experimental and pharmacological nitric oxide donors in human skin. Br J Dermatol 151: 977-983.
28. Seabra AB, Pankotai E, Feher M, et al. 2007; S-Nitrosoglutathione-containing hydrogel increases dermal blood flow in streptozotocin-induced diabetic rats. Br J Dermatol 156: 814-818.
29. Shabani M, Pulfer SK, Bulgin JP, et al. 1996; Enhancement of wound repair with a topically applied nitric oxide-realising polymer. Wound Repair Regen 4: 309-308A.
30. Souza BR, Cardoso JF, Amadeu TP, et al. 2005; Sympathetic denervation alters wound contraction and granulation tissue formation in cutaneous wound healing. Wound Repair Regen 13: 498-505.
31. Tomasek JJ, Gabbiani G, Hinz B, et al. 2002; Myofibroblast and mechano-regulation of connective tissue remodelling. Mol Cell Biol 3: 349-363.
32. Vaalamo M, Mattila L, Johansson N, et al. 1997; Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds. J Invest Dermatol 109: 96-101.
33. Witte MB, Kiyama T, Barbul A. 2002; Nitric oxide enhances experimental wound healing in diabetes. Br J Surg 89: 1594-1601.
34. Woessner JF Jr. 1961; The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 93: 440-447.
35. Zhang Y, Hogg N. 2004; Formation and stability of S-nitrosothiols in RAW 264.7 cells. Am J Physiol Lung 287: L467-474.
36. Zhang Y, Hogg N. 2005; S-Nitrosothiols: cellular formation and transport. Free Radic Biol Med 38: 831-838.