Inactivation of a non-enveloped RNA virus by artificial ribonucleases: Honey bees and Acute bee paralysis virus as a new experimental model for in vivo antiviral activity assessment

Antiviral Research

Volumn 91, Issue 3, 2011, Pages 267-277

  Fedorova, Antonina A ^a   Azzami, Klara ^b   Ryabchikova, Elena I ^a   Spitsyna, Yulia E ^a   Silnikov, Vladimir N ^a   Ritter, Wolfgang ^c   Gross, Hans J ^b   Tautz, Jürgen ^b   Vlassov, Valentin V ^a   Beier, Hildburg ^b   Zenkova, Marina A ^a  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c CVUA Animal Health ^*  (Germany)

Author keywords

Acute bee paralysis virus; Antiviral activity; Artificial ribonucleases; Bee larvae; Killed virus vaccine; Virus inactivation

Indexed keywords

GENOMIC RNA; PHOSPHODIESTERASE; RIBONUCLEASE;

ADULT; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DICISTROVIRIDAE; ELECTRON MICROSCOPY; EMERGENCY TREATMENT; EXPERIMENTAL MODEL; GENOME; GENOMICS; HONEYBEE; HUMAN; IN VIVO STUDY; LARVA; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA VIRUS; SURVIVAL RATE; SUSPENSION; VIRUS INACTIVATION; VIRUS PARTICLE;

ANIMALS; ANTIVIRAL AGENTS; BEES; BIOLOGICAL ASSAY; CELL LINE, TUMOR; DICISTROVIRIDAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LARVA; MICROSCOPY, ELECTRON; PROTEIN ENGINEERING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASES; RNA, VIRAL; VIRUS INACTIVATION;

ACUTE BEE PARALYSIS VIRUS; ANIMALIA; APIS MELLIFERA; APOIDEA; RNA VIRUSES;

EID: 79960471647     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2011.06.011     Document Type: Article

References (30)

1. Aupinel P., Fortini D., Dufour H., Tasei J.-N., Michaud B., Odoux J.-F., Pham-Delègue M.-H. Improvement of artificial feeding in a standard in vitro method for rearing Apis mellifera larvae. Bull. Insectol. 2005, 58:107-111.
2. Bailey L., Gibbs A.J., Woods R.D. Two viruses from adult honey bees (Apis mellifera Linnaeus). Virology 1963, 21:390-395.
3. Bakonyi T., Grabensteiner E., Kolodziejek J., Rusvai M., Topolska G., Ritter W., Nowotny N. Phylogenetic analysis of Acute bee paralysis virus strains. Appl. Environ. Microbiol. 2002, 68:6446-6450.
4. Ball B.V. Acute bee paralysis virus isolates from honeybee colonies infested with Varroa jacobsoni. J. Apic. Res. 1985, 24:115-119.
5. Broo K., Wei J., Marshall D., Brown F., Smith T.J., Johnson J.E., Schneemann A., Siuzdak G. Viral capsid mobility: a dynamic conduit for inactivation. Proc. Natl. Acad. Sci. USA 2001, 98:2274-2277.
6. Davis M., Sagan S.M., Pezacki J.P., Evans D.J., Simmonds P. Bioinformatic and physical characterizations of genome-scale ordered RNA structure in mammalian RNA viruses. J. Virol. 2008, 82:11824-11836.
7. Genersch E., Ashiralieva A., Fries I. Strain- and genotype-specific differences in virulence of Paenibacillus larvae subsp. larvae, a bacterial pathogen causing American foulbrood disease in honeybees. Appl. Environ. Microbiol. 2005, 71:7551-7555.
8. Genersch E., Aubert M. Emerging and re-emerging viruses of the honey bee (Apis mellifera L.). Vet. Res. 2010, 41:54.
9. Goncharova E.P., Kovpak M.P., Ryabchikova E.I., Konevets D.A., Sil'nikov V.N., Zenkova M.A., Vlassov V.V. Viral genome cleavage with artificial ribonucleases: a new method to inactivate RNA-containing viruses. Dokl. Biochem. Biophys. 2009, 427:221-224.
10. Govan V.A., Leat N., Allsopp M., Davison S. Analysis of the complete genome sequence of Acute bee paralysis virus shows that it belongs to the novel group of insect-infecting RNA viruses. Virology 2000, 277:457-463.
11. Hendley J.O., Wenzel R.P., Gwaltney J.M. Transmission of rhinovirus colds by self-inoculation. N. Engl. J. Med. 1973, 288:1361-1364.
12. Konevets D.A., Beck I.E., Beloglazova N.G., Sulimenkov I.V., Sil'nikov V.N., Zenkova M.A., Shishkin G.V., Vlassov V.V. Artificial ribonucleases: synthesis and RNA cleaving properties of cationic conjugates bearing imidazole residues. Tetrahedron 1999, 55:503-512.
13. Kostenko E.V., Laktionov P.P., Vlassov V.V., Zenkova M.A. Downregulation of PGY/MDR1 mRNA level in human KB cells by antisense oligonucleotide conjugates. RNA accessibility in vitro and intracellular antisense activity. Biochim. Biophys. Acta 2002, 1576:143-147.
14. Kovalev N., Burakova E., Silnikov V., Zenkova M., Vlassov V. Artificial ribonucleases: from combinatorial libraries to efficient catalysts of RNA cleavage. Bioorg. Chem. 2006, 34:274-286.
15. Kovalev N.A., Medvedeva D.A., Zenkova M.A., Vlassov V.V. Cleavage of RNA by an amphiphylic compound lacking traditional catalytic groups. Bioorg. Chem. 2008, 36:33-45.
16. Kuznetsova I., Silnikov V.N. Small ribonuclease mimics. Artificial Nucleases 2004, 111-128. Springer-Verlag, Berlin, Heidelberg. M.A. Zenkova (Ed.).
17. Kuznetsova I.L., Zenkova M.A., Gross H.J., Vlassov V.V. Enhanced RNA cleavage within bulge-loops by an artificial ribonuclease. Nucleic Acids Res. 2005, 33:1201-1212.
18. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
19. Mittereder N., March K.L., Trapnell B.C. Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J. Virol. 1996, 70:7498-7509.
20. Newman J.F.E., Brown F., Bailey L., Gibbs A.J. Some physico-chemical properties of two honey-bee picornaviruses. J. Gen. Virol. 1973, 19:405-409.
21. Oliveira A.C., Ishimaru D., Gonçalves R.B., Smith T.J., Mason P., Sá-Carvalho D., Silva J.L. Low temperature and pressure stability of picornaviruses: implications for virus uncoating. Biophys. J. 1999, 76:1270-1279.
22. Peng Y.-S.C., Mussen E., Fong A., Montague M.A., Tyler T. Effects of chlortetracycline of honey bee worker larvae reared in vitro. J. Invertebr. Pathol. 1992, 60:127-133.
23. Randolt K., Gimple O., Geissendörfer J., Reinders J., Prusko C., Mueller M.J., Albert S., Tautz J., Beier H. Immune-related proteins induced in the hemolymph after aseptic and septic injury differ in honey bee worker larvae and adults. Arch. Insect Biochem. Physiol. 2008, 69:155-167.
24. Rogoza, A.V., 1998. Superlipophilicity (xenophilicity) and microlipophilicity of perfluorinated saturated groups. Part 1. Qualitative selection criteria for biologically active substances containing perfluorinated fragments, International Conference on Natural Products and Physiologically Active Substances (ICNPAS-98), November 30-December 6, 1998, Novosibirsk, Russia.
25. Sabatier L., Jouanguy E., Dostert C., Zachary D., Dimarcq J.-L., Bulet P., Imler J.-L. Pherokine-2 and -3. Two Drosophila molecules related to pheromone/odor-binding proteins induced by viral and bacterial infections. Eur. J. Biochem. 2003, 270:3398-3407.
26. Singer B., Fraenkel-Conrat H. Chemical modification of viral ribonucleic acid. VIII. The chemical and biological effects of methylating agents and nitrosoguanidine on tobacco mosaic virus. Biochemistry 1969, 8:3266-3269.
27. Tate J., Liljas L., Scotti P., Christian P., Lin T., Johnson J.E. The crystal structure of cricket paralysis virus: the first view of a new virus family. Nat. Struct. Biol. 1999, 6:765-774.
28. Tamkovich N.V., Malyshev A.V., Konevets D.A., Sil'nikov V.N., Zenkova M.A., Vlassov V.V. Chemical ribonucleases: VII. Effect of positively charged RNA-binding domains and hydrophobic fragments of the conjugates based on 1, 4-diazabicyclo[2.2.2]octane and imidazol on their ribonuclease activity. Bioorg. Khim. 2007, 33:251-260.
29. Tamkovich N.V., Zenkov A.N., Vlassov V.V., Zenkova M.A. An RNA sequence determines the speed of its splitting by artificial ribonucleases. Bioorg. Khim. 2010, 36:223-235.
30. Zenkova M., Beloglazova N., Sil'nikov V., Vlassov V., Giegé R. RNA cleavage by 1,4-diazabicyclo[2.2.2]octane-imidazole conjugates. Methods Enzymol. 2001, 341:468-490.