메뉴 건너뛰기




Volumn 105, Issue 9, 2011, Pages 1268-1274

Maintenance pharmacotherapy of mild and moderate COPD: What is the evidence?

Author keywords

Bronchodilators; Chronic obstructive pulmonary disease; Inhaled corticosteroids; Mild; Moderate; Pharmacotherapy

Indexed keywords

BRONCHODILATING AGENT; BUDESONIDE; BUDESONIDE PLUS FORMOTEROL; CORTICOSTEROID; FLUTICASONE; FLUTICASONE PROPIONATE PLUS SALMETEROL; PLACEBO; TIOTROPIUM BROMIDE; TRIAMCINOLONE;

EID: 79960457533     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2011.02.005     Document Type: Review
Times cited : (13)

References (45)
  • 2
    • 49849084275 scopus 로고    scopus 로고
    • Diagnosis of chronic obstructive pulmonary disease
    • M.B. Stephens, and K.S. Yew Diagnosis of chronic obstructive pulmonary disease Am Fam Physician 78 2008 87 92
    • (2008) Am Fam Physician , vol.78 , pp. 87-92
    • Stephens, M.B.1    Yew, K.S.2
  • 3
    • 40949124799 scopus 로고    scopus 로고
    • Mechanisms of Dyspnea during cycle exercise in symptomatic patients with GOLD stage I chronic obstructive pulmonary disease
    • DOI 10.1164/rccm.200707-1064OC
    • D. Ofir, P. Laveneziana, K.A. Webb, Y.-M. Lam, and D.E. O'Donnell Mechanisms of dyspnea during cycle exercise in symptomatic patients with GOLD stage I chronic obstructive pulmonary disease Am J Respir Crit Care Med 177 2008 622 629 (Pubitemid 351442169)
    • (2008) American Journal of Respiratory and Critical Care Medicine , vol.177 , Issue.6 , pp. 622-629
    • Ofir, D.1    Laveneziana, P.2    Webb, K.A.3    Lam, Y.-M.4    O'Donnell, D.E.5
  • 5
    • 11444256835 scopus 로고    scopus 로고
    • Prevalence of diastolic dysfunction as a possible cause of dyspnea in the elderly
    • DOI 10.1016/j.amjmed.2004.07.048, PII S0002934304006217
    • F. Pedersen, I. Raymond, J. Mehlsen, D. Atar, and P.R. Hildebrandt Prevalence of diastolic dysfunction as a possible cause of dyspnea in the elderly Am J Med 118 2005 25 31 (Pubitemid 40082455)
    • (2005) American Journal of Medicine , vol.118 , Issue.1 , pp. 25-31
    • Pedersen, F.1    Raymond, I.2    Mehlsen, J.3    Atar, D.4    Hildebrandt, P.R.5
  • 12
    • 33745239737 scopus 로고    scopus 로고
    • Misdiagnosis of COPD and asthma in primary care patients 40 years of age and over
    • D.G. Tinkelman, D.B. Price, R.J. Nordyke, and R.J. Halbert Misdiagnosis of COPD and asthma in primary care patients 40 years of age and over J Asthma 43 2006 75 80
    • (2006) J Asthma , vol.43 , pp. 75-80
    • Tinkelman, D.G.1    Price, D.B.2    Nordyke, R.J.3    Halbert, R.J.4
  • 16
    • 0017402583 scopus 로고
    • The natural history of chronic airflow obstruction
    • C. Fletcher, and R. Peto The natural history of chronic airflow obstruction Br Med J 1 1977 1645 1648 (Pubitemid 8124466)
    • (1977) British Medical Journal , vol.1 , Issue.6077 , pp. 1645-1648
    • Fletcher, C.1    Peto, R.2
  • 17
    • 38449115415 scopus 로고    scopus 로고
    • Diagnosis and management of stable chronic obstructive pulmonary disease: A clinical practice guideline from the American College of Physicians
    • A. Qaseem, V. Snow, P. Shekelle, K. Sherif, T.J. Wilt, and S. Weinberger Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline from the American College of Physicians Ann Intern Med 147 2007 633 638 (Pubitemid 351664484)
    • (2007) Annals of Internal Medicine , vol.147 , Issue.9 , pp. 633-638
    • Qaseem, A.1    Snow, V.2    Shekelle, P.3    Sherif, K.4    Wilt, T.J.5    Weinberger, S.6    Owens, D.K.7
  • 18
    • 70249107150 scopus 로고    scopus 로고
    • Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: Analysis from the randomised, placebo-controlled TORCH study
    • C. Jenkins, P. Jones, P. Calverley, B. Celli, J. Anderson, and G. Ferguson Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study Respir Res 10 2009 59
    • (2009) Respir Res , vol.10 , pp. 59
    • Jenkins, C.1    Jones, P.2    Calverley, P.3    Celli, B.4    Anderson, J.5    Ferguson, G.6
  • 19
    • 70349547108 scopus 로고    scopus 로고
    • Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): A prespecified subgroup analysis of a randomised controlled trial
    • M. Decramer, B. Celli, S. Kesten, T. Lystig, S. Mehra, and D.P. Tashkin Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial Lancet 374 2009 1171 1178
    • (2009) Lancet , vol.374 , pp. 1171-1178
    • Decramer, M.1    Celli, B.2    Kesten, S.3    Lystig, T.4    Mehra, S.5    Tashkin, D.P.6
  • 21
    • 4344675455 scopus 로고    scopus 로고
    • Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
    • DOI 10.1016/S0140-6736(04)16900-6, PII S0140673604169006
    • J.C. Hogg Pathophysiology of airflow limitation in chronic obstructive pulmonary disease Lancet 364 2004 709 721 (Pubitemid 39140629)
    • (2004) Lancet , vol.364 , Issue.9435 , pp. 709-721
    • Hogg, J.C.1
  • 23
    • 0034721232 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease
    • DOI 10.1056/NEJM200007273430407
    • P.J. Barnes Chronic obstructive pulmonary disease N Engl J Med 343 2000 269 280 (Pubitemid 30490396)
    • (2000) New England Journal of Medicine , vol.343 , Issue.4 , pp. 269-280
    • Barnes, P.J.1
  • 25
    • 51249091911 scopus 로고    scopus 로고
    • Long-term decline in lung function, utilisation of care and quality of life in modified GOLD stage 1 COPD
    • P.O. Bridevaux, M.W. Gerbase, N.M. Probst-Hensch, C. Schindler, J.M. Gaspoz, and T. Rochat Long-term decline in lung function, utilisation of care and quality of life in modified GOLD stage 1 COPD Thorax 63 2008 768 774
    • (2008) Thorax , vol.63 , pp. 768-774
    • Bridevaux, P.O.1    Gerbase, M.W.2    Probst-Hensch, N.M.3    Schindler, C.4    Gaspoz, J.M.5    Rochat, T.6
  • 26
    • 33751325576 scopus 로고    scopus 로고
    • Defining COPD exacerbations: impact on estimation of incidence and burden in primary care
    • DOI 10.1016/j.pcrj.2006.08.009, PII S147144180600301X
    • J.F. O'Reilly, A.E. Williams, K. Holt, and L. Rice Defining COPD exacerbations: impact on estimation of incidence and burden in primary care Prim Care Respir J 15 2006 346 353 (Pubitemid 44810150)
    • (2006) Primary Care Respiratory Journal , vol.15 , Issue.6 , pp. 346-353
    • O'Reilly, J.F.1    Williams, A.E.2    Holt, K.3    Rice, L.4
  • 28
    • 48949089104 scopus 로고    scopus 로고
    • COPD as a lung disease with systemic consequences-clinical impact, mechanisms, and potential for early intervention
    • M. Decramer, S. Rennard, T. Troosters, D.W. Mapel, N. Giardino, and D. Mannino COPD as a lung disease with systemic consequences-clinical impact, mechanisms, and potential for early intervention COPD 5 2008 235 256
    • (2008) COPD , vol.5 , pp. 235-256
    • Decramer, M.1    Rennard, S.2    Troosters, T.3    Mapel, D.W.4    Giardino, N.5    Mannino, D.6
  • 29
    • 1642534597 scopus 로고    scopus 로고
    • Airway Obstruction Is Common but Unsuspected in Patients Admitted to a General Medicine Service
    • DOI 10.1378/chest.125.1.106
    • D. Zaas, R. Wise, and C. Wiener Airway obstruction is common but Unsuspected in patients admitted to a general Medicine service Chest 125 2004 106 111 (Pubitemid 38114571)
    • (2004) Chest , vol.125 , Issue.1 , pp. 106-111
    • Zaas, D.1    Wise, R.2    Wiener, C.3
  • 30
    • 47849128078 scopus 로고    scopus 로고
    • Knowledge and attitudes of family physicians coming to COPD continuing medical education
    • B.P. Yawn, and P.C. Wollan Knowledge and attitudes of family physicians coming to COPD continuing medical education Int J Chron Obstruct Pulmon Dis 3 2008 June 311 318
    • (2008) Int J Chron Obstruct Pulmon Dis , vol.3 , pp. 311-318
    • Yawn, B.P.1    Wollan, P.C.2
  • 31
    • 0028318612 scopus 로고
    • In chronic obstructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone. An 85-day multicenter trial
    • Inhalation Aerosol Study Group C.
    • COMBIVENT Inhalation Aerosol Study Group In chronic obstructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone. An 85-day multicenter trial Chest 105 1994 1411 1419
    • (1994) Chest , vol.105 , pp. 1411-1419
  • 32
    • 0141558800 scopus 로고    scopus 로고
    • The efficacy and safety of fluticasone propionate (250 μg)/salmeterol (50 μg) combined in the Diskus inhaler for the treatment of COPD
    • DOI 10.1378/chest.124.3.834
    • N.A. Hanania, P. Darken, D. Horstman, C. Reisner, B. Lee, and S. Davis The efficacy and safety of fluticasone propionate (250 μg)/Salmeterol (50 μg) combined in the Diskus inhaler for the treatment of COPD Chest 124 2003 834 843 (Pubitemid 37123298)
    • (2003) Chest , vol.124 , Issue.3 , pp. 834-843
    • Hanania, N.A.1    Darken, P.2    Horstman, D.3    Reisner, C.4    Lee, B.5    Davis, S.6    Shah, T.7
  • 34
    • 0034727828 scopus 로고    scopus 로고
    • Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease
    • Lung Health Study Research Group T.
    • The Lung Health Study Research Group Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease N Engl J Med 343 2000 1902 1909
    • (2000) N Engl J Med , vol.343 , pp. 1902-1909
  • 35
    • 0034643610 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial
    • P.S. Burge, P.M.A. Calverley, P.W. Jones, S. Spencer, J.A. Anderson, and T.K. Maslen Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial BMJ 320 2000 1297 1303 (Pubitemid 30245717)
    • (2000) British Medical Journal , vol.320 , Issue.7245 , pp. 1297-1303
    • Burge, P.S.1    Calverley, P.M.A.2    Jones, P.W.3    Spencer, S.4    Anderson, J.A.5    Maslen, T.K.6
  • 36
    • 0037246565 scopus 로고    scopus 로고
    • Disease severity and the effect of fluticasone propionate on chronic obstructive pulmonary disease exacerbations
    • DOI 10.1183/09031936.03.00013303
    • P.W. Jones, L.R. Willits, P.S. Burge, and P.M.A. Calverley Disease severity and the effect of fluticasone propionate on chronic obstructive pulmonary disease exacerbations Eur Respir J 21 2003 68 73 (Pubitemid 36150303)
    • (2003) European Respiratory Journal , vol.21 , Issue.1 , pp. 68-73
    • Jones, P.W.1    Willits, L.R.2    Burge, P.S.3    Calverley, P.M.A.4
  • 38
    • 48949103222 scopus 로고    scopus 로고
    • Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: Results from the TORCH study
    • B.R. Celli, N.E. Thomas, J.A. Anderson, G.T. Ferguson, C.R. Jenkins, and P.W. Jones Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study Am J Respir Crit Care Med 178 2008 332 338
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 332-338
    • Celli, B.R.1    Thomas, N.E.2    Anderson, J.A.3    Ferguson, G.T.4    Jenkins, C.R.5    Jones, P.W.6
  • 42
    • 79960467792 scopus 로고    scopus 로고
    • US Food and Drug Administration. SPIRIVA HandiHaler label. US Food and Drug Administration. December 2009. Available from:; [accessed 22.07.10]
    • US Food and Drug Administration. SPIRIVA HandiHaler label. US Food and Drug Administration. December 2009. Available from: http://www.accessdata.fda. gov/drugsatfda-docs/label/2009/021395s029lbl.pdf; [accessed 22.07.10].
  • 43
    • 70350112427 scopus 로고    scopus 로고
    • Effect of fluticasone propionate/salmeterol (250/50) on COPD exacerbations and impact on patient outcomes
    • A. Anzueto, G.T. Ferguson, G. Feldman, K. Chinsky, A. Seibert, and A. Emmett Effect of fluticasone propionate/salmeterol (250/50) on COPD exacerbations and impact on patient outcomes COPD 6 2009 320 329
    • (2009) COPD , vol.6 , pp. 320-329
    • Anzueto, A.1    Ferguson, G.T.2    Feldman, G.3    Chinsky, K.4    Seibert, A.5    Emmett, A.6
  • 44
    • 47249103757 scopus 로고    scopus 로고
    • Effect of fluticasone propionate/salmeterol (250/50 microg) or salmeterol (50 microg) on COPD exacerbations
    • G.T. Ferguson, A. Anzueto, R. Fei, A. Emmett, K. Knobil, and C. Kalberg Effect of fluticasone propionate/salmeterol (250/50 microg) or salmeterol (50 microg) on COPD exacerbations Respir Med 102 2008 1099 1108
    • (2008) Respir Med , vol.102 , pp. 1099-1108
    • Ferguson, G.T.1    Anzueto, A.2    Fei, R.3    Emmett, A.4    Knobil, K.5    Kalberg, C.6
  • 45
    • 79960472832 scopus 로고    scopus 로고
    • US Food and Drug Administration SYMBICORT(R) label. US Food and Drug Administration. February 27, 2009. Available from:; [accessed 06.05.10]
    • US Food and Drug Administration SYMBICORT(R) label. US Food and Drug Administration. February 27, 2009. Available from: http://www.accessdata.fda. gov/drugsatfda-docs/label/2009/021929s012lbl.pdf; [accessed 06.05.10].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.