Pharmacological effect of carvacrol on d-galactosamine-induced mitochondrial enzymes and DNA damage by single-cell gel electrophoresis

Journal of Natural Medicines

Volumn 65, Issue 3-4, 2011, Pages 568-577

  Aristatile, Balakrishnan ^a,b   Al Numair, Khalid S ^c   Al Assaf, Abdullah H ^a   Pugalendi, Kodukkur Viswanathan ^d  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b BHARATHIAR UNIVERSITY   (India)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

^d ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidant; Carvacrol; d Galactosamine; DNA damage; Hepatic marker enzymes; Mitochondrial enzymes

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CARVACROL; CYTOCHROME C OXIDASE; GALACTOSAMINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; ISOCITRATE DEHYDROGENASE; MALATE DEHYDROGENASE; MITOCHONDRIAL ENZYME; OXOGLUTARATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SILYMARIN; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; DNA DAMAGE; DRUG DOSE COMPARISON; ENZYME ACTIVITY; GEL ELECTROPHORESIS; LIVER CELL; LIVER MITOCHONDRION; LIVER TOXICITY; LYMPHOCYTE; MALE; MORNING DOSAGE; NONHUMAN; RAT;

ANIMALS; ASCORBIC ACID; COMET ASSAY; DNA DAMAGE; ELECTRON TRANSPORT COMPLEX IV; GALACTOSAMINE; GLUTATHIONE; ISOCITRATE DEHYDROGENASE; KETOGLUTARATE DEHYDROGENASE COMPLEX; MALE; MITOCHONDRIA, LIVER; MONOTERPENES; NADPH DEHYDROGENASE; RATS; RATS, WISTAR; SUCCINATE DEHYDROGENASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; VITAMIN E;

EID: 79960456427     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-011-0544-8     Document Type: Article

References (50)

1. JM Hwang TH Tseng YY Tsai HJ Lee FP Chou CJ Wang CY Chu 2005 Protective effects of baicalein on tert-butyl hydroperoxide-induced hepatic toxicity in rat hepatocytes J Biomed Sci 12 389 397 15917992 10.1007/s11373-005-1572-8 1:CAS:528:DC%2BD2MXhtlajurzM (Pubitemid 40897644)
2. Decker K, Keppler D (1972) Galactosamine induced liver injury. In: Popper H, Schaffner F (eds) Progress in liver disease, vol 4. Grune and Stratton, New York, pp 183-199
3. 2+ on endotoxin- sensitivity by galactosamine challenge: lipid peroxide formation and hepatotoxicity in zymosan primed mice Pharmacol Toxicol 77 81 86 8584508 10.1111/j.1600-0773.1995.tb00993.x 1:CAS:528:DyaK2MXnvVWmu7o%3D
4. R Luft 1995 The development of mitochondrial medicine Biochim Biophys Acta 1271 1 6 7599195 1:CAS:528:DyaK2MXmvVSls7c%3D
5. R Luft BR Landau 1995 Mitochondrial medicine J Intern Med 238 405 421 7595180 10.1111/j.1365-2796.1995.tb01218.x 1:CAS:528:DyaK28XktVartw%3D%3D
6. DC Wallace 1992 Mitochondrial genetics: a paradigm for aging and degenerative diseases Science 256 628 632 1533953 10.1126/science.1533953 1:CAS:528:DyaK38XisV2msL4%3D
7. Zargari A (1990) Medicinal plants, 4th edn. Tehran University Publications, Tehran, pp 42-45
8. N Kirimer KHC Baser G Tumen 1995 Carvacrol rich plants in Turkey Chem Nat Compd 31 37 42 10.1007/BF01167568
9. V Lagouri G Bleskas M Tsimidou S Kokkini D Boskou 1993 Composition and antioxidant activity of essential oils from oregano plants grown wild in Greece Z Lebens Unter und Fors 197 20 23 10.1007/BF01202694 1:CAS:528: DyaK2cXltlWgtA%3D%3D
10. Fenaroli G (2002) Fenaroli's handbook of flavor ingredients, 4th edn. CRC Press, Boca Raton
11. B Aristatile KS Al-Numair C Veeramani KV Pugalendi 2009 Effect of carvacrol on hepatic marker enzymes and antioxidant status in d-galactosamine induced-hepatotoxicity in rats Fundam Clin Pharmacol 23 757 765 19650854 10.1111/j.1472-8206.2009.00721.x 1:CAS:528:DC%2BD1MXhsFWit7rE
12. V Hajhashemi A Ghannadi SK Pezeshkian 2002 Antinociceptive and anti-inflammatory effects of Satureja hortensis L. extracts and essential oil J Ethnopharmacol 82 83 87 12241981 10.1016/S0378-8741(02)00137-X (Pubitemid 35292035)
13. NV Yanishlieva E Marinova MH Gordon VG Reneva 1999 Antioxidant activity and mechanism of action of thymol and carvacrol in two lipid systems Food Chem 64 59 66 10.1016/S0308-8146(98)00086-7 1:CAS:528:DyaK1cXotVSnsrk%3D (Pubitemid 28532687)
14. G Evangelou KS Karkaponnas R Liasko A Nonni D Stefanou G Kallistratos 1997 Dose-related preventive and therapeutic effects of antioxidants- anticarcinogenesis on experimentally induced malignant tumors in Wistar rats Cancer Lett 115 101 105 10.1016/S0304-3835(97)04712-5 (Pubitemid 27139861)
15. LA Shelef 1983 Antimicrobial effects of spices J Food Saf 6 29 44 10.1111/j.1745-4565.1984.tb00477.x
16. N Aligiannis E Kalpoutzakis S Mitaki IB Chinou 2001 Composition and antimicrobial activity of the essential oil of two Organum species J Agric Food Chem 49 4168 4170 11559104 10.1021/jf001494m 1:CAS:528:DC%2BD3MXmtF2mu7o%3D (Pubitemid 32896404)
17. W Sokmen J Serkedjieva D Daferera M Gulluce M Polissiou B Tepe HA Akpular FA Sahin Sokmen 2004 In vitro antioxidant, antimicrobial and antiviral activities of the essential oil and various extracts from herbal parts and callus cultures of Origanum acutidens J Agric Food Chem 52 3309 3312 15161188 10.1021/jf049859g
18. JR Knowles S Roller 2001 Efficacy of chitosan, carvacrol and a hydrogen peroxide-based biocide against food borne microorganisms in suspension and adhered to stainless steel J Food Prot 64 1542 1548 11601703 1:CAS:528:DC%2BD3MXnvVGisb0%3D (Pubitemid 32972544)
19. JR Knowles S Roller DB Murray AS Naidu 2005 Antimicrobial action of carvacrol at different stages of dual-species biofilm development by Staphylococcus aureus and Salmonella typhimurium Appl Environ Microbiol 71 797 803 15691933 10.1128/AEM.71.2.797-803.2005 1:CAS:528:DC%2BD2MXhsVKgsb8%3D (Pubitemid 40223565)
20. Johnson D, Lardy H (1981) Isolation of liver or kidney mitochondria. In: Methods in enzymology. Academic Press, London, pp 94-96
21. JL Bell DN Baron 1960 A colorimetric method for determination of isocitrate dehydrogenase Clin Chem Acta 5 740 747 10.1016/0009-8981(60)90017-6 1:CAS:528:DyaF3MXjtV2r
22. Reed LJ, Mukherjee RB (1969) α-Ketoglutarate dehydrogenase complex from Escherichia coli. In: Colowick SP, Kaplon NO (eds) Methods in enzymology, vol 13. Academic Press, New York, pp 53-61
23. EC Slater WDJ Bonner 1952 The effect of fluoride on succinic oxidase system Biochemistry 52 185 195 1:CAS:528:DyaG3sXjsFyr
24. AH Mehler A Kornberg S Grisolia S Ochoa 1948 The enzymatic mechanism of oxidation-reductions between malate or isocitrate and pyruvate J Biol Chem 174 961 977 18871256 1:CAS:528:DyaH1cXjvVOgsA%3D%3D
25. W Pearl J Cascarano BW Zweifach 1963 Microdetermination of cytochrome oxidase in rat tissues by the oxidation of N-phenyl-p-phenylene diamine or ascorbic acid J Histochem Cytochem 2 102 104 10.1177/11.1.102
26. S Minakami RL Ringler TP Singer 1962 Studies on the respiratory chain-linked dihydrodiphosphopyridine nucleotide dehydrogenase. I. Assay of the enzyme in particulate and in soluble preparation J Biol Chem 237 569 576 14474263 1:CAS:528:DyaF38XmvVelsg%3D%3D
27. WG Niehaus B Samuelson 1968 Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid peroxidation Eur J Biochem 6 126 130 4387188 10.1111/j.1432-1033.1968.tb00428.x 1:CAS:528:DyaF1cXltVaqtL8%3D
28. P Kakkar B Das PN Viswanathan 1984 A modified spectrophotometric assay of superoxide dismutase (SOD) Ind J Biochem Biophys 21 130 132 1:CAS:528:DyaL2cXksFSmsL0%3D (Pubitemid 15207169)
29. JJ Rotruck AL Pope HE Ganther AB Swanson 1973 Selenium: biochemical rates as a component of glutathione peroxidase Science 179 588 590 4686466 10.1126/science.179.4073.588 1:CAS:528:DyaE3sXps1ensg%3D%3D
30. GL Ellman 1959 Tissue sulphydryl groups Arch Biochem Biophys 82 70 77 13650640 10.1016/0003-9861(59)90090-6 1:CAS:528:DyaG1MXotl2ksA%3D%3D
31. JH Roe CA Kuether 1943 The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenylhydrazine derivative of dehydroascorbic acid J Biol Chem 11 145 164
32. H Baker O Frank B De Angelis S Feingold 1980 Plasma tocopherol in man at various times after ingesting free or acetylated tocopherol Nutr Rep Int 21 531 536 1:CAS:528:DyaL3cXhvFKksb0%3D (Pubitemid 10069712)
33. A Boyum 1968 Isolation of mononuclear cells and granulocytes from human blood Sci J Clin Lab Invest 21 97 77 89 1:CAS:528:DyaF1cXktV2htLs%3D
34. A Santhosh S Mathew PR Sudhakaran 1996 Synthesis of sulphated proteoglycans by primary cultures of rat hepatocyte modulation by matrix substratum Mol Cell Biochem 165 1 1 7 8974075 10.1007/BF00229739 1:CAS:528:DyaK2sXhvVOrug%3D%3D
35. NP Singh MT McCoy EL Schneider 1988 A simple technique for quantization of low levels of DNA damage in individual cells Exp Cell Res 175 1 184 191 3345800 10.1016/0014-4827(88)90265-0 1:CAS:528:DyaL1cXhvVWmtbc%3D
36. D Keppler R Lesch W Reutter K Decker 1968 Experimental hepatitis induced by d-galactosamine Exp Mol Pathol 9 279 290 4952077 10.1016/0014-4800(68)90042-7 1:CAS:528:DyaF1cXkvFCnt7g%3D
37. Decker K, Keppler D (1972) Galactosamine-induced liver injury. In: Popper H, Schaffner F (eds) Progress in liver disease, vol 4. Grune and Stratton, New York, pp 183-196
38. Martin P, Friedman LS (1992) Assessment of liver function and diagnostic studies. In: Friedman LS, Keeffe EB (eds) Handbook of liver disease. Churchill Livingstone, Philadelphia, pp 1-14
39. SM Bailey CC Cunningham 2002 Contribution of mitochondria to oxidative stress associated with alcoholic liver disease Free Radic Biol Med 32 1 11 16 11755312 10.1016/S0891-5849(01)00769-9 1:CAS:528:DC%2BD38XitlOn (Pubitemid 34045132)
40. L Puzziferri A Signorile F Guerrieri S Papa V Cuomo L Steardo 2000 Chronic low dose ethanol intake: biochemical characterization of liver mitochondria in rats Life Sci 66 6 477 484 10794064 10.1016/S0024-3205(99)00617- 7 1:CAS:528:DC%2BD3cXlsFKqtQ%3D%3D (Pubitemid 30062920)
41. P Schrauwen MKC Hesselink 2004 Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes Diabetes 53 1412 1417 15161742 10.2337/diabetes.53.6.1412 1:CAS:528:DC%2BD2cXkslCgsr8%3D (Pubitemid 38697650)
42. GM Enns 2003 The contribution of mitochondria to common disorders Mol Genet Metab 80 11 26 14567954 10.1016/j.ymgme.2003.08.009 1:CAS:528: DC%2BD3sXotVChsbw%3D (Pubitemid 37272232)
43. MK Shigenaga TM Hagen BN Ames 1994 Oxidative damage and mitochondrial decay in aging Proc Natl Acad Sci USA 91 23 10771 10778 7971961 10.1073/pnas.91.23.10771 1:CAS:528:DyaK2cXmvFyjtL4%3D (Pubitemid 24349567)
44. J Gao X Tang H Dou Y Fan X Zhao Q Xu 2004 Hepatoprotective activity of Terminalia catappa L. leaves and its two triterpenoids J Pharm Pharmacol 56 11 1449 1455 15525453 10.1211/0022357044733 1:CAS:528:DC%2BD2cXpvFOltbY%3D (Pubitemid 39472075)
45. JC Fernandez-Checa N Kaplowitz C Garcia Ruiz A Colell M Miranda M Mari E Ardite A Morales 1997 GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect Am J Physiol 273 G7 G17 9252504 1:CAS:528:DyaK2sXlt1SrtrY%3D
46. BS Andersson M Rundgren SD Nelson S Harder 1990 N-Acetyl-p-benzoquinone imine-induced changes in the energy metabolism in hepatocytes Chem Biol Interact 75 201 211 2369786 10.1016/0009-2797(90)90118-7 1:CAS:528:DyaK3cXltVyqsb8%3D (Pubitemid 20207275)
47. R Aeschbach J Loliger BC Scott A Murcia J Butler B Halliwell OI Aruoma 1994 Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol Food Chem Toxicol 32 31 36 7510659 10.1016/0278-6915(84)90033-4 1:CAS:528:DyaK2cXis1ymtLg%3D (Pubitemid 24131117)
48. J Blasiak J Kowalik 2001 Protective action of vitamin C against DNA damage induced by selenium-cisplatin conjugate Acta Biochim Pol 48 233 240 11440175 1:CAS:528:DC%2BD3MXjs1Sls7g%3D (Pubitemid 33632626)
49. Aristatile B, Al-Numair KS, Veeramani C (2010) Protective effect of carvacrol on oxidative stress and cellular DNA damage induced by UVB irradiation in human peripheral lymphocytes. J Biochem Mol Toxicol (in press). DOI: 10.1002/jbt.20355
50. TW Yu D Anderson 1997 Reactive oxygen species-induced DNA damage and its modification: a chemical investigation Mutat Res 379 201 210 9357549 1:CAS:528:DyaK2sXlslentLc%3D (Pubitemid 27450540)