Hypertension is associated with marked alterations in sphingolipid biology: A potential role for ceramide

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Spijkers, Léon J A ^a   van den Akker, Rob F P ^a   Janssen, Ben J A ^b   Debets, Jacques J ^b   de Mey, Jo G R ^b   Stroes, Erik S G ^a   van den Born, Bert Jan H ^a   Wijesinghe, Dayanjan S ^c   Chalfant, Charles E ^c   MacAleese, Luke ^d   Eijkel, Gert B ^d   Heeren, Ron M A ^d   Alewijnse, Astrid E ^a   Peters, Stephan L M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d FOM INSTITUTE AMOLF   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM INDEPENDENT PHOSPHOLIPASE A2; CERAMIDE; CYCLOOXYGENASE 1; DIMETHYLSPHINGOSINE; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE; THROMBOXANE SYNTHASE; UNCLASSIFIED DRUG; ARACHIDONIC ACID; THROMBOXANE A2;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY RESISTANCE; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE; CAROTID ARTERY FLOW; CLINICAL ARTICLE; COMMON CAROTID ARTERY; CONTROLLED STUDY; FEMALE; HEART RATE; HUMAN; HYPERTENSION; IMMUNOHISTOCHEMISTRY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MEAN ARTERIAL PRESSURE; NONHUMAN; PLASMA CERAMIDE LEVEL; PROTEIN EXPRESSION; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; VASODILATATION; WISTAR KYOTO RAT; ANESTHESIA; ANIMAL; BIOSYNTHESIS; BLOOD; CAROTID ARTERY; CORONARY BLOOD VESSEL; DRUG EFFECT; IN VITRO STUDY; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; RAT;

RATTUS;

ADULT; ANESTHESIA; ANIMALS; ARACHIDONIC ACID; BLOOD PRESSURE; CAROTID ARTERIES; CERAMIDES; CHROMATOGRAPHY, LIQUID; CORONARY VESSELS; CYCLOOXYGENASE 1; FEMALE; HUMANS; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; MASS SPECTROMETRY; MIDDLE AGED; PHOSPHOLIPASES A2, CALCIUM-INDEPENDENT; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE; THROMBOXANE A2; VASOCONSTRICTION;

EID: 79960449880     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021817     Document Type: Article

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