Fortification of corn masa flour with folic acid in the United States

American Journal of Public Health

Volumn 101, Issue 8, 2011, Pages 1360-1364

  Fleischman, Alan R ^a,b   Oinu, Motoko ^a  

^a March of Dimes Birth Defects Foundation   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID;

ADOLESCENT; ADULT; AFRICAN AMERICAN; ARTICLE; DIET SUPPLEMENTATION; ETHNOLOGY; FEMALE; FLOUR; HISPANIC; HUMAN; MAIZE; NEURAL TUBE DEFECT; PREGNANCY; UNITED STATES;

ADOLESCENT; ADULT; AFRICAN AMERICANS; FEMALE; FLOUR; FOLIC ACID; FOOD, FORTIFIED; HISPANIC AMERICANS; HUMANS; NEURAL TUBE DEFECTS; PREGNANCY; UNITED STATES; YOUNG ADULT; ZEA MAYS;

EID: 79960441735     PISSN: 00900036     EISSN: 15410048     Source Type: Journal    
DOI: 10.2105/AJPH.2011.300135     Document Type: Review

References (48)

1. Centers for Disease Control and Prevention. Spina bifida and anencephaly before and after folic acid mandate- United States, 1995-1996 and 1999- 2000. MMWR Morb Mortal Wkly Rep. 2004;53(17):362-365.
2. Botto LD, Moore CA, Khoury MJ, Erickson JD. Neural-tube defects. N Engl J Med. 1999;341(20):1509-1519. (Pubitemid 29526355)
3. Williams LJ, Rasmussen SA, Flores A, Kirby RS, Edmonds LD. Decline in the prevalence of spina bifida and anencephaly by race/ethnicity: 1995- 2002. Pediatrics. 2005;116(3): 580-586. (Pubitemid 44336670)
4. Sadler TW. Embryology of neural tube development. Am J Med Genet C Semin Med Genet. 2005;135C(1):2-8. (Pubitemid 40593667)
5. Finer LB, Henshaw SK. Disparities in rates of unintended pregnancy in the United States, 1994 and 2001. Perspect Sex Reprod Health. 2006;38(2): 90-96. (Pubitemid 43882311)
6. MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet. 1991;338(8760): 131-137.
7. Czeizel AE, Dudas I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med. 1992;327(26):1832-1835. (Pubitemid 23003073)
8. Centers for Disease Control and Prevention. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Recomm Rep. 1992; 41(RR-14):1-7.
9. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: National Academies Press; 1998.
10. US Food and Drug Administration. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid, final rule. 21 CFR parts 136, 137 and 139. Fed Reg. 1996:8781-8797.
11. Honein MA, Paulozzi LJ, Mathews TJ, Erickson JD, Wong LY. Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. JAMA. 2001;285(23): 2981-2986. (Pubitemid 32550116)
12. Mathews TJ. NCHS Health E-Stats 2009. Trends in spina bifida and anencephalus in the United States, 1991-2006. Available at: http://www.cdc.gov/ nchs/data/hestat/spine-anen/spine-anen.pdf. Published April 2009. Accessed April 4, 2011.
13. Williams LJ, Mai CT, Edmonds LD, et al. Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States. Teratology. 2002;66(1): 33-39. (Pubitemid 34734388)
14. McDowell MA, Lacher DA, Pfeiffer CM, et al. Blood Folate Levels: The Latest NHANES Results. Hyattsville, MD: National Center for Health Statistics; 2008. NCHS Data Brief no. 6.
15. Pfeiffer CM, Johnson CL, Jain RB, et al. Trends in blood folate and vitamin B-12 concentrations in the United States, 1988-2004. Am J Clin Nutr. 2007;86(3): 718-727. (Pubitemid 47435840)
16. Heseker HB, Mason JB, Selhub J, Rosenberg IH, Jacques PF. Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid. Br J Nutr. 2009;102(2):173-180.
17. Mosley BS, Cleves MA, Siega-Riz AM, et al. Neural tube defects and maternal folate intake among pregnancies conceived after folic acid fortification in the United States. Am J Epidemiol. 2009; 169(1):9-17.
18. Centers for Disease Control and Prevention. CDC grand rounds: additional opportunities to prevent neural tube defects with folic acid fortification. MMWR Morb Mortal Wkly Rep. 2010; 59(31):980-984.
19. Canfield MA, Ramadhani TA, Shaw GM, et al. Anencephaly and spina bifida among Hispanics: maternal, sociodemographic, and acculturation factors in the National Birth Defects Prevention Study. Birth Defects Res A Clin Mol Teratol. 2009;85(7):637-646.
20. Volcik KA, Blanton SH, Tyerman GH, et al. Methylenetetrahydrofolate reductase and spina bifida: evaluation of level of defect and maternal genotypic risk in Hispanics. Am J Med Genet. 2000; 95(1):21-27.
21. US Census Bureau. Hispanic population in the United States: 1970 to 2050. Available at: http://www.census.gov/population/www/socdemo/hispanic/Hispanic- pop-presentation.html. Accessed June 22, 2010.
22. Martin JA, Hamilton BE, Sutton PD, et al. Births: final data for 2006. Natl Vital Stat Rep. 2009;57(7):1-102.
23. Yang QH, Carter HK, Mulinare J, Berry RJ, Friedman JM, Erickson JD. Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: findings from the National Health and Nutrition Examination Survey, 2001-2002. Am J Clin Nutr. 2007;85(5):1409-1416. (Pubitemid 46740486)
24. Prue CE, Hamner HC, Flores AL. Effects of folic acid awareness on knowledge and consumption for the prevention of birth defects among Hispanic women in several US communities. J Womens Health (Larchmt). 2010;19(4): 689-698.
25. Tinker SC, Cogswell ME, Devine O, Berry RJ. Folic acid intake among US women aged 15-44 years, National Health and Nutrition Examination Survey, 2003-2006. Am J Prev Med. 2010;38(5):534-542.
26. Gallup Organization and March of Dimes Foundation. Improving Preconception Health: Women's Knowledge and Use of Folic Acid. White Plains, NY: March of Dimes Foundation; 2008.
27. Centers for Disease Control and Prevention. Trends in folic acid supplement intake among women of reproductive age-California, 2002-2006. MMWR Morb Mortal Wkly Rep. 2007; 56(42):1106-1109.
28. Mandatory food enrichment. Basel, Switzerland: Roche Vitamins Europe; 2003. Nutri View special issue 2003.
29. Chen LT, Rivera MA. The Costa Rican experience: reduction of neural tube defects following food fortification programs. Nutr Rev. 2004;62(6 pt 2): S40-S43. (Pubitemid 38916079)
30. Hamner HC, Mulinare J, Cogswell ME, et al. Predicted contribution of folic acid fortification of corn masa flour to the usual folic acid intake for the US population: National Health and Nutrition Examination Survey 2001- 2004. Am J Clin Nutr. 2009;89(1): 305-315.
31. Burton KE, Steele FM, Jefferies L, Pike OA, Dunn ML. Effect of micronutrient fortification on nutritional and other properties of nixtamal tortillas. Cereal Chem. 2008;85(1):70-75. (Pubitemid 351158462)
32. Dunn ML, Serna-Sandivar SO, Sanchez-Hernandez D, Griffin RW. Commercial evaluation of a continuous micronutrient fortification process for nixtamal tortillas. Cereal Chem. 2008; 85(6):746-752.
33. Dunn ML, Serna-Sandivar SO, Turner EH. Industrial approaches to micronutrient fortification of traditional nixtamal tortillas. Cereal Foods World. 2007;52(5):240-248.
34. Yang Q, Cogswell ME, Hamner HC, et al. Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003- 2006. Am J Clin Nutr. 2010;91(1): 64-72.
35. European Food Safety Authority Scientific Cooperation Working Group on Analysis of Risks and Benefits of Fortification of Food With Folic Acid. Appendix 2: EFSA meeting summary report. Folic acid: an update on scientific developments. In: ECSO Report on Analysis of Risks and Benefits of Fortification of Food with Folic Acid. Parma, Italy: European Food Safety Authority; 2009:94-115. Available at: http://www.efsa.europa.eu/en/supporting/doc/3e.pdf. Accessed June 22, 2010.
36. Johnston RB Jr. Will increasing folic acid in fortified grain products further reduce neural tube defects without causing harm? Consideration of the evidence. Pediatr Res. 2008;63(1):2-8.
37. Clarke R, Halsey J, Lewington S, et al. Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med. 2010;170(18):1622-1631.
38. Whitrow MJ, Moore VM, Rumbold AR, Davies MJ. Effect of supplemental folic acid in pregnancy on childhood asthma: a prospective birth cohort study. Am J Epidemiol. 2009;170(12):1486-1493.
39. Simpson JL, Bailey LB, Pietrzik K, Shane B,Holzgreve W. Micronutrients and women of reproductive potential: required dietary intake and consequences of dietary deficiency or excess. Part I-folate, vitamin B12, vitamin B6. J Matern Fetal Neonatal Med. 2010;23(12):1323-1343.
40. Mills JL, Von Kohorn I, Conley MR, et al. Low vitamin B-12 concentrations in patients without anemia: the effect of folic acid fortification of grain. Am J Clin Nutr. 2003;77(6):1474-1477. (Pubitemid 39655282)
41. Cole BF, Baron JA, Sandler RS, et al. Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA. 2007;297(21): 2351-2359. 42 (Pubitemid 46883748)
42. Mason JB, Dickstein A, Jacques PF, et al. A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev. 2007;16(7): 1325-1329. (Pubitemid 47076861)
43. Jaszewski R, Misra S, Tobi M, et al. Folic acid supplementation inhibits recurrence of colorectal adenomas: a randomized chemoprevention trial. World J Gastroenterol. 2008;14(28): 4492-4498.
44. Logan RF, Grainge MJ, Shepherd VC, Armitage NC, Muir KR. Aspirin and folic acid for the prevention of recurrent colorectal adenomas. Gastroenterology. 2008;134(1):29-38. (Pubitemid 350309319)
45. Federal Food, Drug and Cosmetic Act, Definitions and Standards for Food, 21 USC x341.
46. Food and drugs. Statement of purpose. 21 CFR x104.20.
47. Committee on Use of Dietary Reference Intakes in Nutrition Labeling. Dietary Reference Intakes: Guiding Principles for Nutrition Labeling and Fortification. Washington, DC: National Academies Press; 2003.
48. Food and drugs. Folic acid (folacin). 21 CFR x172.345.