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Volumn 187, Issue 1, 2011, Pages 74-81

Forced expression of HLA-DM at the surface of dendritic cells increases loading of synthetic peptides on MHC class II molecules and modulates T cell responses

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTYLGLYCYLSERYLTHREONYLASPARTYLTYROSYLGLYCYLISOLEUCYLLEUCYLGLUTAMINYLISOLEUCYLASPARAGINYLSERYLARGININE; HLA DM ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROPYLLYSYLTYROSYLVALYLLYSYLGLUTAMINYLASPARAGINYLTHREONYLLEUCYLLYSYLALANYLTHREONINE; SYNTHETIC PEPTIDE; THREONYLGLYCYLARGINYLMETHIONYLLEUCYLGLYCYLTHREONYLHISTIDINYLTHREONYLMETHIONYLGLUTAMYLVALYLTHREONYLVALYLTYROSYLHISTIDINE; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 79960431418     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002747     Document Type: Article
Times cited : (11)

References (45)
  • 1
    • 41149130863 scopus 로고    scopus 로고
    • Multiple roles for CD4+ T cells in anti-tumor immune responses
    • Kennedy, R., and E. Celis. 2008. Multiple roles for CD4+ T cells in anti-tumor immune responses. Immunol. Rev. 222: 129-144.
    • (2008) Immunol. Rev. , vol.222 , pp. 129-144
    • Kennedy, R.1    Celis, E.2
  • 2
    • 22144439081 scopus 로고    scopus 로고
    • Tumor antigen-specific T helper cells in cancer immunity and immunotherapy
    • Knutson, K. L., and M. L. Disis. 2005. Tumor antigen-specific T helper cells in cancer immunity and immunotherapy. Cancer Immunol. Immunother. 54: 721-728.
    • (2005) Cancer Immunol. Immunother. , vol.54 , pp. 721-728
    • Knutson, K.L.1    Disis, M.L.2
  • 3
    • 63949087382 scopus 로고    scopus 로고
    • Identification of novel helper epitopes of MAGE-A4 tumour antigen: Useful tool for the propagation of Th1 cells
    • Ohkuri, T., D. Wakita, K. Chamoto, Y. Togashi, H. Kitamura, and T. Nishimura. 2009. Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells. Br. J. Cancer 100: 1135-1143.
    • (2009) Br. J. Cancer , vol.100 , pp. 1135-1143
    • Ohkuri, T.1    Wakita, D.2    Chamoto, K.3    Togashi, Y.4    Kitamura, H.5    Nishimura, T.6
  • 4
    • 7444253937 scopus 로고    scopus 로고
    • Immunization of HLA-A*0201 and/or HLA-DPbeta1*04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen
    • Khong, H. T., J. C. Yang, S. L. Topalian, R. M. Sherry, S. A. Mavroukakis, D. E. White, and S. A. Rosenberg. 2004. Immunization of HLA-A*0201 and/or HLA-DPbeta1*04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen. J. Immunother. 27: 472-477.
    • (2004) J. Immunother. , vol.27 , pp. 472-477
    • Khong, H.T.1    Yang, J.C.2    Topalian, S.L.3    Sherry, R.M.4    Mavroukakis, S.A.5    White, D.E.6    Rosenberg, S.A.7
  • 6
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II a b dimers and facilitates peptide loading
    • Denzin, L. K., and P. Cresswell. 1995. HLA-DM induces CLIP dissociation from MHC class II a b dimers and facilitates peptide loading. Cell 82: 155-165.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 7
    • 0028789975 scopus 로고
    • The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif
    • Lindstedt, R., M. Liljedahl, A. Péléraux, P. A. Peterson, and L. Karlsson. 1995. The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif. Immunity 3: 561-572.
    • (1995) Immunity , vol.3 , pp. 561-572
    • Lindstedt, R.1    Liljedahl, M.2    Péléraux, A.3    Peterson, P.A.4    Karlsson, L.5
  • 10
    • 33644550942 scopus 로고    scopus 로고
    • Amino-terminal flanking residues determine the conformation of a peptide-class II MHC complex
    • Lovitch, S. B., Z. Pu, and E. R. Unanue. 2006. Amino-terminal flanking residues determine the conformation of a peptide-class II MHC complex. J. Immunol. 176: 2958-2968.
    • (2006) J. Immunol. , vol.176 , pp. 2958-2968
    • Lovitch, S.B.1    Pu, Z.2    Unanue, E.R.3
  • 13
    • 11144230451 scopus 로고    scopus 로고
    • Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins
    • Wong, S. H., L. Santambrogio, and J. L. Strominger. 2004. Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins. Proc. Natl. Acad. Sci. USA 101: 17783-17788.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 17783-17788
    • Wong, S.H.1    Santambrogio, L.2    Strominger, J.L.3
  • 16
    • 0034711230 scopus 로고    scopus 로고
    • Functional characterization of a lysosomal sorting motif in the cytoplasmic tail of HLA-DObeta
    • Brunet, A., A. Samaan, F. Deshaies, T. J. Kindt, and J. Thibodeau. 2000. Functional characterization of a lysosomal sorting motif in the cytoplasmic tail of HLA-DObeta. J. Biol. Chem. 275: 37062-37071.
    • (2000) J. Biol. Chem. , vol.275 , pp. 37062-37071
    • Brunet, A.1    Samaan, A.2    Deshaies, F.3    Kindt, T.J.4    Thibodeau, J.5
  • 18
    • 0026517022 scopus 로고
    • Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor
    • Hewitt, C. R. A., J. R. Lamb, J. Hayball, M. Hill, M. J. Owen, and R. E. O'Hehir. 1992. Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor. J. Exp. Med. 175: 1493-1499.
    • (1992) J. Exp. Med. , vol.175 , pp. 1493-1499
    • Hewitt, C.R.A.1    Lamb, J.R.2    Hayball, J.3    Hill, M.4    Owen, M.J.5    O'Hehir, R.E.6
  • 19
    • 0036537831 scopus 로고    scopus 로고
    • A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells
    • DOI 10.1016/S0022-1759(02)00013-3, PII S0022175902000133
    • Son, Y. I., S. Egawa, T. Tatsumi, R. E. Redlinger, Jr., P. Kalinski, and T. Kanto. 2002. A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells. J. Immunol. Methods 262: 145-157. (Pubitemid 34450739)
    • (2002) Journal of Immunological Methods , vol.262 , Issue.1-2 , pp. 145-157
    • Son, Y.-I.1    Egawa, S.-I.2    Tatsumi, T.3    Redlinger Jr., R.E.4    Kalinski, P.5    Kanto, T.6
  • 21
    • 47249089545 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-peptide complexes internalize using a clathrin- And dynamin-independent endocytosis pathway
    • Walseng, E., O. Bakke, and P. A. Roche. 2008. Major histocompatibility complex class II-peptide complexes internalize using a clathrin- and dynamin-independent endocytosis pathway. J. Biol. Chem. 283: 14717-14727.
    • (2008) J. Biol. Chem. , vol.283 , pp. 14717-14727
    • Walseng, E.1    Bakke, O.2    Roche, P.A.3
  • 22
    • 0027288930 scopus 로고
    • Differential effect of polymorphism at HLA-DR1 b-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides
    • Newton-Nash, D. K., and D. D. Eckels. 1993. Differential effect of polymorphism at HLA-DR1 b-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides. J. Immunol. 150: 1813-1821.
    • (1993) J. Immunol. , vol.150 , pp. 1813-1821
    • Newton-Nash, D.K.1    Eckels, D.D.2
  • 24
    • 0028919184 scopus 로고
    • Poor loading of major histocompatibility complex class II molecules with endogenously synthesized short peptides in the absence of invariant chain
    • Busch, R., I. Y. Vturina, J. Drexler, F. Momburg, and G. J. Hämmerling. 1995. Poor loading of major histocompatibility complex class II molecules with endogenously synthesized short peptides in the absence of invariant chain. Eur. J. Immunol. 25: 48-53.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 48-53
    • Busch, R.1    Vturina, I.Y.2    Drexler, J.3    Momburg, F.4    Hämmerling, G.J.5
  • 26
    • 0037169536 scopus 로고    scopus 로고
    • Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules
    • Falk, K., J. M. Lau, L. Santambrogio, V. M. Esteban, F. Puentes, O. Rotzschke, and J. L. Strominger. 2002. Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules. J. Biol. Chem. 277: 2709-2715.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2709-2715
    • Falk, K.1    Lau, J.M.2    Santambrogio, L.3    Esteban, V.M.4    Puentes, F.5    Rotzschke, O.6    Strominger, J.L.7
  • 27
    • 10944263783 scopus 로고    scopus 로고
    • "Chemical analogues" of HLA-DM can induce a peptide-receptive state in HLA-DR molecules
    • Marin-Esteban, V., K. Falk, and O. Rötzschke. 2004. "Chemical analogues" of HLA-DM can induce a peptide-receptive state in HLA-DR molecules. J. Biol. Chem. 279: 50684-50690.
    • (2004) J. Biol. Chem. , vol.279 , pp. 50684-50690
    • Marin-Esteban, V.1    Falk, K.2    Rötzschke, O.3
  • 29
    • 0034047126 scopus 로고    scopus 로고
    • The functional role of class II-associated invariant chain peptide (CLIP) in its ability to variably modulate immune responses
    • Chaturvedi, P., R. Hengeveld, M. A. Zechel, E. Lee-Chan, and B. Singh. 2000. The functional role of class II-associated invariant chain peptide (CLIP) in its ability to variably modulate immune responses. Int. Immunol. 12: 757-765.
    • (2000) Int. Immunol. , vol.12 , pp. 757-765
    • Chaturvedi, P.1    Hengeveld, R.2    Zechel, M.A.3    Lee-Chan, E.4    Singh, B.5
  • 30
    • 0023201652 scopus 로고
    • Cytogenetics of somatic cell hybrids. II. Modal karyotypes and mosaicism in mouse mutant cell lines: LM(tk-), A9, and Rag
    • Chen, T. R. 1987. Cytogenetics of somatic cell hybrids. II. Modal karyotypes and mosaicism in mouse mutant cell lines: LM(tk-), A9, and Rag. Cancer Genet. Cytogenet. 24: 95-107.
    • (1987) Cancer Genet. Cytogenet. , vol.24 , pp. 95-107
    • Chen, T.R.1
  • 33
    • 0025370731 scopus 로고
    • Degenerate binding of immunogenic peptides to HLA-DR proteins on B cell surfaces
    • Busch, R., G. Strang, K. Howland, and J. B. Rothbard. 1990. Degenerate binding of immunogenic peptides to HLA-DR proteins on B cell surfaces. Int. Immunol. 2: 443-451.
    • (1990) Int. Immunol. , vol.2 , pp. 443-451
    • Busch, R.1    Strang, G.2    Howland, K.3    Rothbard, J.B.4
  • 34
    • 0028326785 scopus 로고
    • Peptide binding to surface class II molecules is the major pathway of formation of immunogenic class II-peptide complexes for viable antigen presenting cells
    • Nygard, N. R., K. S. Giacoletto, C. Bono, J. Gorka, S. Kompelli, and B. D. Schwartz. 1994. Peptide binding to surface class II molecules is the major pathway of formation of immunogenic class II-peptide complexes for viable antigen presenting cells. J. Immunol. 152: 1082-1093.
    • (1994) J. Immunol. , vol.152 , pp. 1082-1093
    • Nygard, N.R.1    Giacoletto, K.S.2    Bono, C.3    Gorka, J.4    Kompelli, S.5    Schwartz, B.D.6
  • 35
    • 0034232504 scopus 로고    scopus 로고
    • Endocytic recycling is required for the presentation of an exogenous peptide via MHC class II molecules
    • Pathak, S. S., and J. S. Blum. 2000. Endocytic recycling is required for the presentation of an exogenous peptide via MHC class II molecules. Traffic 1: 561-569.
    • (2000) Traffic , vol.1 , pp. 561-569
    • Pathak, S.S.1    Blum, J.S.2
  • 36
    • 40149087830 scopus 로고    scopus 로고
    • Exogenous CLIP localizes into endocytic compartment of cells upon internalization: Implications for antigen presentation by MHC class II molecules
    • Mukherjee, R., P. Chaturvedi, E. Lee-Chan, and B. Singh. 2008. Exogenous CLIP localizes into endocytic compartment of cells upon internalization: implications for antigen presentation by MHC class II molecules. Mol. Immunol. 45: 2166-2176.
    • (2008) Mol. Immunol. , vol.45 , pp. 2166-2176
    • Mukherjee, R.1    Chaturvedi, P.2    Lee-Chan, E.3    Singh, B.4
  • 37
    • 0742305009 scopus 로고    scopus 로고
    • Linking molecular and cellular events in T-cell activation and synapse formation
    • Krogsgaard, M., J. B. Huppa, M. A. Purbhoo, and M. M. Davis. 2003. Linking molecular and cellular events in T-cell activation and synapse formation. Semin. Immunol. 15: 307-315.
    • (2003) Semin. Immunol. , vol.15 , pp. 307-315
    • Krogsgaard, M.1    Huppa, J.B.2    Purbhoo, M.A.3    Davis, M.M.4
  • 39
    • 32844454744 scopus 로고    scopus 로고
    • HLA-DM expression is elevated in ETV6-AML1 translocation-positive pediatric acute lymphoblastic leukemia
    • Jastaniah, W. A., A. J. Alessandri, G. S. Reid, and K. R. Schultz. 2006. HLA-DM expression is elevated in ETV6-AML1 translocation-positive pediatric acute lymphoblastic leukemia. Leuk. Res. 30: 487-489.
    • (2006) Leuk. Res. , vol.30 , pp. 487-489
    • Jastaniah, W.A.1    Alessandri, A.J.2    Reid, G.S.3    Schultz, K.R.4
  • 40
    • 33750219785 scopus 로고    scopus 로고
    • Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients
    • Oldford, S. A., J. D. Robb, D. Codner, V. Gadag, P. H. Watson, and S. Drover. 2006. Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients. Int. Immunol. 18: 1591-1602.
    • (2006) Int. Immunol. , vol.18 , pp. 1591-1602
    • Oldford, S.A.1    Robb, J.D.2    Codner, D.3    Gadag, V.4    Watson, P.H.5    Drover, S.6
  • 41
    • 0030963614 scopus 로고    scopus 로고
    • Induction of Th1 and Th2 CD4+ T cell responses: The alternative approaches
    • Constant, S. L., and K. Bottomly. 1997. Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu. Rev. Immunol. 15: 297-322.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 297-322
    • Constant, S.L.1    Bottomly, K.2
  • 42
    • 0026440236 scopus 로고
    • HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
    • Riberdy, J. M., J. R. Newcomb, M. J. Surman, J. A. Barbosa, and P. Cresswell. 1992. HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature 360: 474-477.
    • (1992) Nature , vol.360 , pp. 474-477
    • Riberdy, J.M.1    Newcomb, J.R.2    Surman, M.J.3    Barbosa, J.A.4    Cresswell, P.5
  • 44
    • 0034212481 scopus 로고    scopus 로고
    • Increasing the potency of MHC class II-presented epitopes by linkage to Ii-Key peptide
    • PII S0264410X00000670
    • Humphreys, R. E., S. Adams, G. Koldzic, B. Nedelescu, E. von Hofe, and M. Xu. 2000. Increasing the potency of MHC class II-presented epitopes by linkage to Ii-Key peptide. Vaccine 18: 2693-2697. (Pubitemid 30211577)
    • (2000) Vaccine , vol.18 , Issue.24 , pp. 2693-2697
    • Humphreys, R.E.1    Adams, S.2    Koldzic, G.3    Nedelescu, B.4    Von Hofe, E.5    Xu, M.6


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