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Volumn 4, Issue 5, 2011, Pages 885-890

A novel chimeric DNA vaccine: Enhancement of preventive and therapeutic efficacy of DNA vaccine by fusion of Mucin 1 to a heat shock protein 70 gene

Author keywords

Cancer; Chimeric DNA vaccine; HSP70; Immunotherapy; Muc1

Indexed keywords

DNA VACCINE; HEAT SHOCK PROTEIN 70; HYBRID PROTEIN; MUCIN 1;

EID: 79960412308     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.525     Document Type: Article
Times cited : (19)

References (25)
  • 1
    • 7444252305 scopus 로고    scopus 로고
    • On the road to a tumor cell vaccine: 20 Years of cellular immunotherapy
    • DOI 10.1016/j.vaccine.2003.12.036, PII S0264410X04003159
    • Yannelli JR and Wroblewski JM: On the road to a tumor cell vaccine: 20 years of cellular immunotherapy. Vaccine 23: 97-113, 2004. (Pubitemid 39446365)
    • (2004) Vaccine , vol.23 , Issue.1 , pp. 97-113
    • Yannelli, J.R.1    Wroblewski, J.M.2
  • 2
    • 77951695279 scopus 로고    scopus 로고
    • DNA vaccines: Developing new strategies against cancer
    • Mar 28, E-pub ahead of print
    • Fioretti D, Iurescia S, Fazio VM and Rinaldi M: DNA vaccines: developing new strategies against cancer. J Biomed Biotechnol: Mar 28, 2010 (E-pub ahead of print).
    • (2010) J Biomed Biotechnol
    • Fioretti, D.1    Iurescia, S.2    Fazio, V.M.3    Rinaldi, M.4
  • 4
    • 78649697657 scopus 로고    scopus 로고
    • Human chemokine MIP1alpha increases efficiency of targeted DNA fusion vaccines
    • Nov 4, E-pub ahead of print
    • Ruffini PA, Grodeland G, Fredriksen AB and Bogen B: Human chemokine MIP1alpha increases efficiency of targeted DNA fusion vaccines. Vaccine: Nov 4, 2010 (E-pub ahead of print).
    • (2010) Vaccine
    • Ruffini, P.A.1    Grodeland, G.2    Fredriksen, A.B.3    Bogen, B.4
  • 5
    • 0023741252 scopus 로고
    • A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats
    • Gendler S, Taylor-Papadimitriou J, Duhig T, Rothbard J and Burchell J: A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. J Biol Chem 263: 12820-12823, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 12820-12823
    • Gendler, S.1    Taylor-Papadimitriou, J.2    Duhig, T.3    Rothbard, J.4    Burchell, J.5
  • 8
    • 0036512171 scopus 로고    scopus 로고
    • Roles of heat-shock proteins in innate and adaptive immunity
    • Srivastava P: Roles of heat-shock proteins in innate and adaptive immunity. Nat Rev Immunol 2: 185-194, 2002.
    • (2002) Nat Rev Immunol , vol.2 , pp. 185-194
    • Srivastava, P.1
  • 9
    • 0034652784 scopus 로고    scopus 로고
    • Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene
    • Chen CH, Wang TL, Hung CF, et al: Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene. Cancer Res 60: 1035-1042, 2000.
    • (2000) Cancer Res , vol.60 , pp. 1035-1042
    • Chen, C.H.1    Wang, T.L.2    Hung, C.F.3
  • 10
    • 0033695064 scopus 로고    scopus 로고
    • A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins
    • Cho BK, Palliser D, Guillen E, et al: A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins. Immunity 12: 263-272, 2000.
    • (2000) Immunity , vol.12 , pp. 263-272
    • Cho, B.K.1    Palliser, D.2    Guillen, E.3
  • 12
    • 20544433550 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1038/ni1201
    • Binder RJ and Srivastava PK: Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells. Nat Immunol 6: 593-599, 2005. (Pubitemid 41710730)
    • (2005) Nature Immunology , vol.6 , Issue.6 , pp. 593-599
    • Binder, R.J.1    Srivastava, P.K.2
  • 13
    • 51049087087 scopus 로고    scopus 로고
    • Synergistic tumoricidal effect of combined hMUC1 vaccination and hNIS radioiodine gene therapy
    • Jeon YH, Choi Y, Yoon SO, Kim CW and Chung JK: Synergistic tumoricidal effect of combined hMUC1 vaccination and hNIS radioiodine gene therapy. Mol Cancer Ther 7: 2252-2260, 2008.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2252-2260
    • Jeon, Y.H.1    Choi, Y.2    Yoon, S.O.3    Kim, C.W.4    Chung, J.K.5
  • 14
    • 14844325736 scopus 로고    scopus 로고
    • Exosomes: A new delivery system for tumor antigens in cancer immunotherapy
    • Cho JA, Yeo DJ, Son HY, et al: Exosomes: a new delivery system for tumor antigens in cancer immunotherapy. Int J Cancer 114: 613-622, 2005.
    • (2005) Int J Cancer , vol.114 , pp. 613-622
    • Cho, J.A.1    Yeo, D.J.2    Son, H.Y.3
  • 15
    • 31444451699 scopus 로고    scopus 로고
    • Intramuscular immunization with plasmid coexpressing tumour antigen and Flt-3L results in potent tumour regression
    • DOI 10.1038/sj.gt.3302639, PII 3302639
    • Fong CL, Mok CL and Hui KM: Intramuscular immunization with plasmid coexpressing tumour antigen and Flt-3L results in potent tumour regression. Gene Ther 13: 245-256, 2006. (Pubitemid 43148647)
    • (2006) Gene Therapy , vol.13 , Issue.3 , pp. 245-256
    • Fong, C.L.1    Mok, C.-L.2    Hui, K.M.3
  • 16
    • 33645521225 scopus 로고    scopus 로고
    • DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells
    • Fredriksen AB, Sandlie I and Bogen B: DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells. Mol Ther 13: 776-785, 2006.
    • (2006) Mol Ther , vol.13 , pp. 776-785
    • Fredriksen, A.B.1    Sandlie, I.2    Bogen, B.3
  • 17
    • 33947640160 scopus 로고    scopus 로고
    • Delivery of antigen to CD40 induces protective immune responses against tumors
    • Schjetne KW, Fredriksen AB and Bogen B: Delivery of antigen to CD40 induces protective immune responses against tumors. J Immunol 178: 4169-4176, 2007. (Pubitemid 46492367)
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4169-4176
    • Schjetne, K.W.1    Fredriksen, A.B.2    Bogen, B.3
  • 18
    • 34548821867 scopus 로고    scopus 로고
    • Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences
    • DOI 10.1182/blood-2006-06-032938
    • Fredriksen AB and Bogen B: Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences. Blood 110: 1797-1805, 2007. (Pubitemid 47443890)
    • (2007) Blood , vol.110 , Issue.6 , pp. 1797-1805
    • Fredriksen, A.B.1    Bogen, B.2
  • 21
    • 33645869270 scopus 로고    scopus 로고
    • Th2-dominated antitumor immunity induced by DNA immunization with the genes coding for a basal core peptide PDTRP and GM-CSF
    • Chu Y, Xia M, Lin Y, et al: Th2-dominated antitumor immunity induced by DNA immunization with the genes coding for a basal core peptide PDTRP and GM-CSF. Cancer Gene Ther 13: 510-519, 2006.
    • (2006) Cancer Gene Ther , vol.13 , pp. 510-519
    • Chu, Y.1    Xia, M.2    Lin, Y.3
  • 22
    • 33645095443 scopus 로고    scopus 로고
    • A MUC1/IL-18 DNA vaccine induces antitumor immunity and increased survival in MUC1 transgenic mice
    • Snyder LA, Goletz TJ, Gunn GR, et al: A MUC1/IL-18 DNA vaccine induces antitumor immunity and increased survival in MUC1 transgenic mice. Vaccine 24: 3340-3352, 2006.
    • (2006) Vaccine , vol.24 , pp. 3340-3352
    • Snyder, L.A.1    Goletz, T.J.2    Gunn, G.R.3
  • 23
    • 0141625683 scopus 로고    scopus 로고
    • Augmentation of DNA vaccine potency through secretory heat shock protein-mediated antigen targeting
    • DOI 10.1016/S1046-2023(03)00136-1
    • Hauser H and Chen SY: Augmentation of DNA vaccine potency through secretory heat shock protein-mediated antigen targeting. Methods 31: 225-231, 2003. (Pubitemid 37162795)
    • (2003) Methods , vol.31 , Issue.3 , pp. 225-231
    • Hauser, H.1    Chen, S.-Y.2
  • 24
    • 2942748077 scopus 로고    scopus 로고
    • Secretory heat-shock protein as a dendritic cell-targeting molecule: A new strategy to enhance the potency of genetic vaccines
    • DOI 10.1038/sj.gt.3302160
    • Hauser H, Shen L, Gu QL, Krueger S and Chen SY: Secretory heat-shock protein as a dendritic cell-targeting molecule: a new strategy to enhance the potency of genetic vaccines. Gene Ther 11: 924-932, 2004. (Pubitemid 38786607)
    • (2004) Gene Therapy , vol.11 , Issue.11 , pp. 924-932
    • Hauser, H.1    Shen, L.2    Gu, Q.-L.3    Krueger, S.4    Chen, S.-Y.5
  • 25
    • 0347122087 scopus 로고    scopus 로고
    • Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo
    • DOI 10.1038/nm962
    • Millar DG, Garza KM, Odermatt B, et al: Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo. Nat Med 9: 1469-1476, 2003. (Pubitemid 38004773)
    • (2003) Nature Medicine , vol.9 , Issue.12 , pp. 1469-1476
    • Millar, D.G.1    Garza, K.M.2    Odermatt, B.3    Elford, A.R.4    Ono, N.5    Li, Z.6    Ohashi, P.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.