Comprehensive Analysis of Single- and Multi-Target Activity Cliffs Formed by Currently Available Bioactive Compounds

Chemical Biology and Drug Design

Volumn 78, Issue 2, 2011, Pages 224-228

  Wassermann, Anne M ^a   Dimova, Dilyana ^a   Bajorath, Jürgen ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Activity cliffs; Activity landscapes; Compound potency; Data mining; Polypharmacology; Structure activity relationships; Target families

Indexed keywords

ACTIVITY CLIFF; CHEMICAL COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENANTIOSELECTIVITY; HUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; STRUCTURE ACTIVITY RELATION;

DATABASES AS TOPIC; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960362109     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01150.x     Document Type: Article

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