Nuclear receptor retinoid-related orphan receptor α1 modulates the metabolic activity of human osteoblasts

Journal of Cellular Biochemistry

Volumn 112, Issue 8, 2011, Pages 2160-2169

  Benderdour, Mohamed ^a   Fahmi, Hassan ^b   Beaudet, François ^a   Fernandes, Julio C ^a   Shi, Qin ^a  

^a HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

Author keywords

inflammatory responses; osteoblast metabolism markers; ROR 1

Indexed keywords

ALKALINE PHOSPHATASE; CELL MARKER; CYCLOOXYGENASE 2; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOCALCIN; PROSTAGLANDIN E2; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RNA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL METABOLISM; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; INFLAMMATION; MINERALIZATION; MONOCYTE; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ALKALINE PHOSPHATASE; ANTIGENS, DIFFERENTIATION; CALCIFICATION, PHYSIOLOGIC; CELL LINE, TUMOR; COLLAGEN TYPE I; CYCLOOXYGENASE 2; DINOPROSTONE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1; OSTEOBLASTS; OSTEOCALCIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79960358205     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23141     Document Type: Article

References (35)

1. Ahn KS, Aggarwal BB,. 2005. Transcription factor NF-kappaB: A sensor for smoke and stress signals. Ann NY Acad Sci 1056: 218-233. (Pubitemid 43030980)
2. Bordji K, Grillasca JP, Gouze JN, Magdalou J, Schohn H, Keller JM, Bianchi A, Dauca M, Netter P, Terlain B,. 2000. Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes. J Biol Chem 275: 12243-12250. (Pubitemid 30237804)
3. Crofford LJ, Tan B, McCarthy CJ, Hla T,. 1997. Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes. Arthritis Rheum 40: 226-236. (Pubitemid 27114086)
4. Cunnane G, FitzGerald O, Hummel KM, Youssef PP, Gay RE, Gay S, Bresnihan B,. 2001. Synovial tissue protease gene expression and joint erosions in early rheumatoid arthritis. Arthritis Rheum 44: 1744-1753. (Pubitemid 32758219)
5. Delerive P, Monte D, Dubois G, Trottein F, Fruchart-Najib J, Mariani J, Fruchart JC, Staels B,. 2001. The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response. EMBO Rep 2: 42-48. (Pubitemid 32229720)
6. Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G,. 1997. Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89: 747-754. (Pubitemid 27516177)
7. Enmark E, Gustafsson JA,. 1996. Orphan nuclear receptors-The first eight years. Mol Endocrinol 10: 1293-1307. (Pubitemid 26423220)
8. Giguere V,. 1999. Orphan nuclear receptors: From gene to function. Endocr Rev 20: 689-725. (Pubitemid 30654814)
9. Giguere V, Tini M, Flock G, Ong E, Evans RM, Otulakowski G,. 1994. Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors. Genes Dev 8: 538-553.
10. Gregory CA, Gunn WG, Peister A, Prockop DJ,. 2004. An Alizarin red-based assay of mineralization by adherent cells in culture: Comparison with cetylpyridinium chloride extraction. Anal Biochem 329: 77-84. (Pubitemid 38596903)
11. Iqbal J, Zaidi M,. 2005. Molecular regulation of mechanotransduction. Biochem Biophys Res Commun 328: 751-755. (Pubitemid 40208313)
12. Jetten AM, Ueda E,. 2002. Retinoid-related orphan receptors (RORs): Roles in cell survival, differentiation and disease. Cell Death Differ 9: 1167-1171. (Pubitemid 35331763)
13. Jimi E, Ghosh S,. 2005. Role of nuclear factor-kappaB in the immune system and bone. Immunol Rev 208: 80-87. (Pubitemid 41746386)
14. Kaneko M, Tomita T, Nakase T, Ohsawa Y, Seki H, Takeuchi E, Takano H, Shi K, Takahi K, Kominami E, Uchiyama Y, Yoshikawa H, Ochi T,. 2001. Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis. Rheumatology (Oxford) 40: 247-255.
15. Karsenty G,. 1999. The genetic transformation of bone biology. Genes Dev 13: 3037-3051. (Pubitemid 30016104)
16. Kopmels B, Mariani J, haye-Bouchaud N, Audibert F, Fradelizi D, Wollman EE,. 1992. Evidence for a hyperexcitability state of staggerer mutant mice macrophages. J Neurochem 58: 192-199.
17. Lau P, Bailey P, Dowhan DH, Muscat GE,. 1999. Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD. Nucleic Acids Res 27: 411-420. (Pubitemid 29210002)
18. Lu M, Rabie AB,. 2006. Matrix metalloproteinase-9 regulates graft bone resorption. Angle Orthod 76: 598-604. (Pubitemid 44066014)
19. Lyashenko N, Weissenbock M, Sharir A, Erben RG, Minami Y, Hartmann C,. 2010. Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded. Dev Dyn 239: 2266-2277.
20. McBroom LD, Flock G, Giguere V,. 1995. The nonconserved hinge region and distinct amino-terminal domains of the ROR alpha orphan nuclear receptor isoforms are required for proper DNA bending and ROR alpha-DNA interactions. Mol Cell Biol 15: 796-808.
21. Meyer T, Kneissel M, Mariani J, Fournier B,. 2000. In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism. Proc Natl Acad Sci USA 97: 9197-9202. (Pubitemid 30626697)
22. Migita H, Satozawa N, Lin JH, Morser J, Kawai K,. 2004. RORalpha1 and RORalpha4 suppress TNF-alpha-induced VCAM-1 and ICAM-1 expression in human endothelial cells. FEBS Lett 557: 269-274. (Pubitemid 38115908)
23. Morsczeck C,. 2006. Gene expression of runx2, Osterix, c-fos, DLX-3, DLX-5, and MSX-2 in dental follicle cells during osteogenic differentiation in vitro. Calcif Tissue Int 78: 98-102. (Pubitemid 43228089)
24. Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de CB,. 2002. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108: 17-29. (Pubitemid 34137009)
25. Pozo D, Garcia-Maurino S, Guerrero JM, Calvo JR,. 2004. mRNA expression of nuclear receptor RZR/RORalpha, melatonin membrane receptor MT, and hydroxindole-O-methyltransferase in different populations of human immune cells. J Pineal Res 37: 48-54. (Pubitemid 38969020)
26. Raisz LG, Pilbeam CC, Fall PM,. 1993. Prostaglandins: Mechanisms of action and regulation of production in bone. Osteoporos Int 3 (Suppl 1): 136-140. (Pubitemid 23099913)
27. Ram M, Sherer Y, Shoenfeld Y,. 2006. Matrix metalloproteinase-9 and autoimmune diseases. J Clin Immunol 26: 299-307. (Pubitemid 44051377)
28. Schrader M, Danielsson C, Wiesenberg I, Carlberg C,. 1996. Identification of natural monomeric response elements of the nuclear receptor RZR/ROR. They also bind COUP-TF homodimers. J Biol Chem 271: 19732-19736.
29. Shi Q, Vaillancourt F, Cote V, Fahmi H, Lavigne P, Afif H, Di Battista JA, Fernandes JC, Benderdour M,. 2006. Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal. Arthritis Res Ther 8: R159.
30. Shi Q, Benderdour M, Lavigne P, Ranger P, Fernandes JC,. 2007. Evidence for two distinct pathways in TNFalpha-induced membrane and soluble forms of ICAM-1 in human osteoblast-like cells isolated from osteoarthritic patients. Osteoarthritis Cartilage 15: 300-308. (Pubitemid 46238245)
31. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC,. 1985. Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85. (Pubitemid 16258399)
32. Steinhilber D, Brungs M, Werz O, Wiesenberg I, Danielsson C, Kahlen JP, Nayeri S, Schrader M, Carlberg C,. 1995. The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human B lymphocytes. J Biol Chem 270: 7037-7040.
33. Sundvold H, Lien S,. 2001. Identification of a novel peroxisome proliferator-activated receptor (PPAR) gamma promoter in man and transactivation by the nuclear receptor RORalpha1. Biochem Biophys Res Commun 287: 383-390. (Pubitemid 32917609)
34. Yan C, Wang H, Aggarwal B, Boyd DD,. 2004. A novel homologous recombination system to study 92kDa type IV collagenase transcription demonstrates that the NF-kappaB motif drives the transition from a repressed to an activated state of gene expression. FASEB J 18: 540-541.
35. Yang X, Karsenty G,. 2002. Transcription factors in bone: Developmental and pathological aspects. Trends Mol Med 8: 340-345. (Pubitemid 34733388)