Antiproliferative activity of dmoPTA-Ru(II) complexes against human solid tumor cells

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 15, 2011, Pages 4568-4571

  Ríos Luci, Carla ^a   León, Leticia G ^a   Mena Cruz, Adrián ^a   Pérez Roth, Eduardo ^a   Lorenzo Luis, Pablo ^a   Romerosa, Antonio ^b   Padrón, José M ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b UNIVERSITY OF ALMERÍA   (Spain)

Author keywords

Antitumor drugs; Cell cycle arrest; Hydrosoluble phosphines; Organometallic drugs; Ruthenium complexes

Indexed keywords

3,7 DIMETHYL 1,3,7 TRIAZA 5 PHOSPHABICYCLO[3.3.1]NONANE RUTHENIUM COMPLEX; ANTINEOPLASTIC AGENT; CISPLATIN; ORGANOMETALLIC COMPOUND; RUTHENIUM COMPLEX; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; COLON CANCER; CONTROLLED STUDY; DRUG DNA BINDING; DRUG SYNTHESIS; FEMALE; HELA CELL; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; SOLID TUMOR;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COORDINATION COMPLEXES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; NEOPLASMS; RUTHENIUM;

EID: 79960352000     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.05.116     Document Type: Article

References (30)

1. A.W. Prestayko, J.C. D'Aoust, B.F. Issell, and S.T. Crooke Cancer Treat. Rev. 6 1979 17
2. B. Stordal, and M. Davey IUBMB Life 59 2007 696
3. N. Pabla, and Z. Dong Kidney Int. 73 2008 994
4. L. Messori, A. Casini, C. Gabbiani, E. Michelucci, L. Cubo, C. Rios-Luci, J.M. Padrón, C. Navarro-Ranninger, and A.G. Quiroga ACS Med. Chem. Lett. 1 2010 381
5. A.M. Montaña, and C. Batalla Curr. Med. Chem. 16 2009 2235
6. Y.P. Ho, S.C. Au-Yeung, and K.K. To Med. Res. Rev. 23 2003 633
7. T. Gianferrara, I. Bratsos, and E. Alessio Dalton Trans. 2009 7588
8. P.C. Bruijnincx, and P.J. Sadler Curr. Opin. Chem. Biol. 12 2008 197
9. C.S. Allardyce, and P.J. Dyson Platinum Met. Rev. 45 2001 62
10. E.S. Antonarakis, and A. Emadi Cancer Chemother. Pharmacol. 66 2010 1
11. G. Süss-Fink Dalton Trans. 2010 1673
12. S.J. Dougan, and P.J. Sadler Chimia 61 2007 704
13. P.J. Dyson Chimia 61 2007 698
14. A. Romerosa, T. Campos-Malpartida, C. Lidrissi, M. Saoud, M. Serrano-Ruiz, P. Peruzzini, J.A. Garrido-Cárdenas, and F. García-Maroto Inorg. Chem. 45 2006 1289
15. A. Romerosa, M. Saoud, T. Campos-Malpartida, C. Lidrissi, M. Serrano-Ruiz, P. Peruzzini, J.A. Garrido-Cárdenas, and F. García-Maroto Eur. J. Inorg. Chem. 2007 2803
16. A. Mena-Cruz, P. Lorenzo-Luis, A. Romerosa, M. Saoud, and M. Serrano-Ruiz Inorg. Chem. 46 2007 6120
17. A. Mena-Cruz, P. Lorenzo-Luis, A. Romerosa, and M. Serrano-Ruiz Inorg. Chem. 47 2008 2246
18. A. Mena-Cruz, P. Lorenzo-Luis, V. Pasarelli, A. Romerosa, and M. Serrano-Ruiz Dalton Trans. 40 2011 3237
19. P.O. Miranda, J.M. Padrón, J.I. Padrón, J. Villar, and V.S. Martín ChemMedChem 1 2006 323
20. A. Monks, D.A. Scudiero, P. Skehan, R.H. Shoemaker, K.D. Paull, D.T. Vistica, C. Hose, J. Langley, P. Cronice, M. Vaigro-Wolf, M. Gray-Goodrich, H. Campbell, and M.R. Mayo J. Natl. Cancer Inst. 83 1991 757
21. P.E. Pizao, G.J. Peters, J. van Ark-Otte, L.A. Smets, E. Smitskamp-Wilms, B. Winograd, H.M. Pinedo, and G. Giaccone Eur. J. Cancer 29A 1993 1566
22. C. Scolaro, A. Bergamo, L. Brescacin, R. Delfino, M. Cocchietto, G. Laurenczy, T.J. Geldbach, G. Sava, and P.J. Dyson J. Med. Chem. 48 2005 4161
23. L.G. León, R.M. Carballo, M.C. Vega-Hernández, P.O. Miranda, V.S. Martín, J.I. Padrón, and J.M. Padrón ChemMedChem 3 2008 1740
24. J.M. Padrón, and G.J. Peters Invest. New Drugs 24 2006 195
25. C. Gaiddon, P. Jeannequin, P. Bischoff, M. Pfeffer, C. Sirlin, and J.P. Loeffler J. Pharmacol. Exp. Ther. 315 2005 1403
26. C. Tan, S. Hu, J. Liu, and L. Ji Eur. J. Med. Chem. 46 2011 1555
27. S. Chatterjee, S. Kundu, A. Bhattacharyya, C.G. Hartinger, and P.J. Dyson J. Biol. Inorg. Chem. 13 2008 1149
28. R.E. Aird, J. Cummings, A.A. Ritchie, M. Muir, R.E. Morris, H. Chen, P.J. Sadler, and D.I. Jodrell Br. J. Cancer 86 2002 1652
29. A. Bergamo, R. Gagliardi, V. Scarcia, A. Furlani, E. Alessio, G. Mestroni, and G. Sava J. Pharmacol. Exp. Ther. 289 1999 559
30. S. Zorzet, A. Bergamo, M. Cocchietto, A. Sorc, B. Gava, E. Alessio, E. Iengo, and G. Sava J. Pharmacol. Exp. Ther. 295 2000 927